chr1 : 221,972,131 – 221,972,883

752 bp 66 TFs 1 linked gene

This 752 bp open chromatin element is linked to LINC02474 and is bound by 66 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
LINC02474		5.8 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

66 transcription factors

ATF2 3 datasets

ChIP GM12878 ENCSR961PPA.ATF2.GM12878 104 bp overlap

ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 93 bp overlap

ChIP K-562 ENCSR869IUD.ATF2.K-562 64 bp overlap

ATF3 2 datasets

ChIP K-562 ENCSR632DCH.ATF3.K-562 95 bp overlap

ChIP K-562 ENCSR028UIU.ATF3.K-562 62 bp overlap

ATF7 2 datasets

ChIP GM12878 ENCFF037PYH 122 bp overlap

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 61 bp overlap

BRD2 2 datasets

ChIP SUM149PT_DMSO GSE131097.BRD2.SUM149PT_DMSO 95 bp overlap

ChIP SUM149PT_JQ1 GSE131097.BRD2.SUM149PT_JQ1 129 bp overlap

BRD3 1 dataset

ChIP H-1_DE GSE126661.BRD3.H-1_DE 271 bp overlap

BRD4 1 dataset

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 174 bp overlap

CREB1 1 dataset

ChIP MCF-7 ENCFF867SAS 54 bp overlap

CREBBP 1 dataset

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 119 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF346MCV 237 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 197 bp overlap

EP300 1 dataset

ChIP PC-3 GSE147455.EP300.PC-3 126 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 737 bp overlap

ChIP DE DE-FOXA2-2 645 bp overlap

Foxl2 1 dataset

Motif DE_12h DE_12h-Foxl2_MA1607.2 10 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 668 bp overlap

ChIP DE DE-GATA4-2 635 bp overlap

Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 732 bp overlap

ChIP DE DE-GATA6-2 750 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 506 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 614 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 525 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 550 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 580 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 476 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 350 bp overlap

HNF4A 1 dataset

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

HSF1 1 dataset

Motif DE_12h DE_12h-HSF1_MA0486.2 13 bp overlap

HSF2 1 dataset

Motif DE_12h DE_12h-HSF2_MA0770.1 13 bp overlap

HSF4 1 dataset

Motif DE_12h DE_12h-HSF4_MA0771.1 13 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

JUN 7 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 385 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 266 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 580 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 413 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 196 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 423 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 185 bp overlap

JUND 1 dataset

ChIP GP5D_SIRAD21 GSE51234.JUND.GP5D_SIRAD21 163 bp overlap

MED1 1 dataset

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 224 bp overlap

MED25 1 dataset

ChIP PC-3_FLAG GSE133445.MED25.PC-3_FLAG 313 bp overlap

Mecom 1 dataset

Motif DE_12h DE_12h-Mecom_MA0029.2 11 bp overlap

NANOG 4 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 242 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 581 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 597 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 189 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_12h DE_12h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

Nr2f6 1 dataset

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

PLAGL2 1 dataset

Motif DE_12h DE_12h-PLAGL2_MA1548.2 8 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 6 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 303 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 516 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 640 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 752 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 135 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PPARD 1 dataset

Motif DE_12h DE_12h-PPARD_MA1550.2 14 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_12h DE_12h-RXRG_MA0856.1 14 bp overlap

Rxra 1 dataset

Motif DE_12h DE_12h-Rxra_MA0512.2 14 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 288 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 647 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 660 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 573 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 644 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 752 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 694 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 685 bp overlap

SMAD3 2 datasets

ChIP NCI-H441 GSE51509.SMAD3.NCI-H441 221 bp overlap

ChIP NCI-H441_SIITTF1 GSE51509.SMAD3.NCI-H441_SIITTF1 194 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 186 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 193 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 170 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 752 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 165 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 313 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 632 bp overlap

SUPT5H 1 dataset

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 277 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TEAD2 1 dataset

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

TEAD4 1 dataset

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

TFAP2B 1 dataset

Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap

TFAP2C 1 dataset

Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap

TFAP4 1 dataset

ChIP DLD-1 GSE46935.TFAP4.DLD-1 196 bp overlap

TP53 1 dataset

ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 89 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 407 bp overlap

ZNF667 1 dataset

Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap