chr12 : 38,898,100 – 38,898,307

207 bp 68 TFs 2 linked genes

This 207 bp open chromatin element is linked to CPNE8 and CPNE8-AS1 and is bound by 68 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
CPNE8		7.3 kb	Proximal	Proximity
CPNE8-AS1		8.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

68 transcription factors

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 207 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 207 bp overlap

BRD4 1 dataset

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 127 bp overlap

CDK9 1 dataset

ChIP HEK293T_SIBRD4 GSE51633.CDK9.HEK293T_SIBRD4 162 bp overlap

CDX2 1 dataset

ChIP Caco-2_PROLIF GSE23436.CDX2.Caco-2_PROLIF 148 bp overlap

CHD7 1 dataset

ChIP WA01 ENCSR000AVA.CHD7.WA01 133 bp overlap

CTCF 1 dataset

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 184 bp overlap

Dmrt1 1 dataset

Motif ES_0h ES_0h-Dmrt1_MA1603.2 9 bp overlap

ELL2 2 datasets

ChIP HeLa GSE40632.ELL2.HeLa 207 bp overlap

ChIP HeLa_DOX_EGF GSE40632.ELL2.HeLa_DOX_EGF 179 bp overlap

ESR1 2 datasets

ChIP T-47D ENCSR000BQD.ESR1.T-47D 115 bp overlap

ChIP T-47D ENCSR000BJS.ESR1.T-47D 138 bp overlap

ESR1_Y537S 1 dataset

ChIP T-47D_E2 GSE94493.ESR1_Y537S.T-47D_E2 89 bp overlap

FOXA1 7 datasets

ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 140 bp overlap

ChIP T-47D_E2_TAM ERP000380.FOXA1.T-47D_E2_TAM 120 bp overlap

ChIP T-47D_JC4743 GSE126004.FOXA1.T-47D_JC4743 207 bp overlap

ChIP T-47D_JC4744 GSE126004.FOXA1.T-47D_JC4744 207 bp overlap

ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 177 bp overlap

ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 207 bp overlap

ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 207 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 166 bp overlap

ChIP DE DE-FOXA2-2 152 bp overlap

FOXO1::ELF1 1 dataset

Motif ES_0h ES_0h-FOXO1ELF1_MA1953.2 13 bp overlap

GATA1 1 dataset

Motif DE_12h DE_12h-GATA1_MA0035.5 7 bp overlap

GATA3 1 dataset

ChIP T-47D ENCSR000BMX.GATA3.T-47D 133 bp overlap

GATA6 2 datasets

ChIP DE DE-GATA6-1 207 bp overlap

ChIP DE DE-GATA6-2 104 bp overlap

GRHL2 1 dataset

ChIP T-47D GSE99680.GRHL2.T-47D 189 bp overlap

HNF4A 1 dataset

Motif DE_12h DE_12h-HNF4A_MA1494.2 14 bp overlap

KDM1A 2 datasets

ChIP H1 ENCFF696SGD 77 bp overlap

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 51 bp overlap

MED1 1 dataset

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 207 bp overlap

MEN1 1 dataset

ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 78 bp overlap

MYBL2 1 dataset

Motif DE_12h DE_12h-MYBL2_MA0777.1 15 bp overlap

NANOG 4 datasets

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 119 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 207 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 207 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 207 bp overlap

NKX2-1 1 dataset

ChIP NCI-H1819 GSE39998.NKX2-1.NCI-H1819 207 bp overlap

NR2F1 1 dataset

Motif DE_12h DE_12h-NR2F1_MA1537.2 13 bp overlap

NR3C1 2 datasets

ChIP HeLa-B2_P65KD_TA_TNFA GSE24518.NR3C1.HeLa-B2_P65KD_TA_TNFA 94 bp overlap

ChIP HeLa-B2_TA GSE24518.NR3C1.HeLa-B2_TA 164 bp overlap

Nr2f6 1 dataset

Motif DE_12h DE_12h-Nr2f6_MA0677.2 13 bp overlap

PGR 2 datasets

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 207 bp overlap

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 193 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 3 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 207 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 207 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 207 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PPARA::RXRA 1 dataset

Motif DE_12h DE_12h-PPARARXRA_MA1148.2 17 bp overlap

PPARD 1 dataset

Motif DE_12h DE_12h-PPARD_MA1550.2 14 bp overlap

PRDM9 1 dataset

Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap

Prdm4 1 dataset

Motif DE_12h DE_12h-Prdm4_MA1647.3 11 bp overlap

RAD21 1 dataset

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 207 bp overlap

RARA 1 dataset

ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 203 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 206 bp overlap

RELA 1 dataset

ChIP HeLa-B2_TNFA GSE24518.RELA.HeLa-B2_TNFA 139 bp overlap

RXRB 1 dataset

Motif DE_12h DE_12h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_12h DE_12h-RXRG_MA0856.1 14 bp overlap

Rxra 1 dataset

Motif DE_12h DE_12h-Rxra_MA0512.2 14 bp overlap

SMARCA4 2 datasets

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 207 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 207 bp overlap

SMARCC1 1 dataset

ChIP G-401_Dox GSE71504.SMARCC1.G-401_Dox 174 bp overlap

SMC3 1 dataset

ChIP HeLa-Kyoto_WAPL_PDS-depleted GSE102884.SMC3.HeLa-Kyoto_WAPL_PDS-depleted 180 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 207 bp overlap

SOX8 1 dataset

Motif ES_0h ES_0h-SOX8_MA0868.3 7 bp overlap

SP1 2 datasets

ChIP H1 ENCFF263FUH 207 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 207 bp overlap

STAG1 2 datasets

ChIP HeLa GSE126990.STAG1.HeLa 207 bp overlap

ChIP HeLa-Kyoto GSE138405.STAG1.HeLa-Kyoto 207 bp overlap

STAT3 5 datasets

ChIP MDA-MB-468_EtOH GSE85579.STAT3.MDA-MB-468_EtOH 147 bp overlap

ChIP T-47D_JC4739 GSE126004.STAT3.T-47D_JC4739 168 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 207 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 193 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 207 bp overlap

Sox17 1 dataset

Motif ES_0h ES_0h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif ES_0h ES_0h-Sox5_MA0087.3 8 bp overlap

TEAD1 4 datasets

ChIP HEK293_siE1A GSE130135.TEAD1.HEK293_siE1A 207 bp overlap

ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 178 bp overlap

ChIP keratinocyte GSE138727.TEAD1.keratinocyte 207 bp overlap

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 181 bp overlap

TEAD4 13 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 207 bp overlap

ChIP H1 ENCFF778PAX 67 bp overlap

ChIP HEK293_siE1A GSE130135.TEAD4.HEK293_siE1A 180 bp overlap

ChIP MCF-7_DMSO GSE125594.TEAD4.MCF-7_DMSO 207 bp overlap

ChIP MCF-7_Veh GSE125594.TEAD4.MCF-7_Veh 207 bp overlap

ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 207 bp overlap

ChIP PC-9_1DF_DMSO GSE131687.TEAD4.PC-9_1DF_DMSO 207 bp overlap

ChIP PC-9_2DF GSE131687.TEAD4.PC-9_2DF 207 bp overlap

ChIP PC-9_2DF_DMSO GSE131687.TEAD4.PC-9_2DF_DMSO 139 bp overlap

ChIP SNU-216 GSE44416.TEAD4.SNU-216 207 bp overlap

ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 207 bp overlap

ChIP T-47D_Veh GSE125594.TEAD4.T-47D_Veh 207 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 207 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 201 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 207 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 207 bp overlap

THRB 1 dataset

Motif DE_12h DE_12h-THRB_MA1574.2 13 bp overlap

YAP1 2 datasets

ChIP MCF-7 GSE107013.YAP1.MCF-7 207 bp overlap

ChIP hiPSC GSE111930.YAP1.hiPSC 154 bp overlap

YY1AP1 5 datasets

ChIP HEK293_siCtrl GSE130135.YY1AP1.HEK293_siCtrl 205 bp overlap

ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 207 bp overlap

ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 207 bp overlap

ChIP T-47D_E2 GSE125594.YY1AP1.T-47D_E2 207 bp overlap

ChIP T-47D_Veh GSE125594.YY1AP1.T-47D_Veh 207 bp overlap

ZNF189 1 dataset

Motif ES_0h ES_0h-ZNF189_MA1725.2 9 bp overlap

ZNF384 1 dataset

Motif ES_0h ES_0h-ZNF384_MA1125.2 8 bp overlap

ZNF410 1 dataset

Motif ES_0h ES_0h-ZNF410_MA0752.2 16 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 178 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 163 bp overlap