chr12 : 27,521,881 – 27,522,535
654 bp 128 TFs 1 linked gene
This 654 bp open chromatin element is linked to PPFIBP1 and is bound by 128 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PPFIBP1 1.6 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:27,516,881 – 27,527,535
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
128 transcription factors
Source
Cell type
ALX3 1 dataset
Motif DE_36h DE_36h-ALX3_MA0634.2 6 bp overlap
ARGFX 1 dataset
Motif DE_36h DE_36h-ARGFX_MA1463.2 8 bp overlap
Alx1 1 dataset
Motif DE_36h DE_36h-Alx1_MA0854.2 8 bp overlap
Alx4 1 dataset
Motif DE_36h DE_36h-Alx4_MA0853.2 12 bp overlap
Arid3a 1 dataset
Motif DE_36h DE_36h-Arid3a_MA0151.1 6 bp overlap
Arx 1 dataset
Motif DE_36h DE_36h-Arx_MA0874.2 10 bp overlap
BNC2 1 dataset
ChIP SK-N-SH ENCFF174EMC 425 bp overlap
BRD4 2 datasets
ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 305 bp overlap
ChIP SW480 GSE73319.BRD4.SW480 228 bp overlap
CEBPB 1 dataset
ChIP K-562 ENCSR000EHE.CEBPB.K-562 115 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF093OYK 271 bp overlap
DMRTA2 1 dataset
Motif DE_36h DE_36h-DMRTA2_MA1478.2 6 bp overlap
DRGX 1 dataset
Motif DE_36h DE_36h-DRGX_MA1481.2 6 bp overlap
DUX4 1 dataset
Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap
DUXA 1 dataset
Motif DE_36h DE_36h-DUXA_MA0884.2 13 bp overlap
Dux 1 dataset
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
EMX1 1 dataset
Motif DE_36h DE_36h-EMX1_MA0612.3 6 bp overlap
EMX2 1 dataset
Motif DE_36h DE_36h-EMX2_MA0886.2 6 bp overlap
EN1 1 dataset
Motif DE_36h DE_36h-EN1_MA0027.3 6 bp overlap
EN2 1 dataset
Motif DE_36h DE_36h-EN2_MA0642.3 7 bp overlap
EOMES 5 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 318 bp overlap
ERF::FOXI1 2 datasets
Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_60h DE_60h-ERFFOXI1_MA1935.2 10 bp overlap
ESX1 1 dataset
Motif DE_36h DE_36h-ESX1_MA0644.3 7 bp overlap
ETV5::FOXO1 2 datasets
Motif DE_36h DE_36h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_60h DE_60h-ETV5FOXO1_MA1947.2 10 bp overlap
EVX1 1 dataset
Motif DE_36h DE_36h-EVX1_MA0887.2 6 bp overlap
EVX2 1 dataset
Motif DE_36h DE_36h-EVX2_MA0888.2 6 bp overlap
EWSR1-FLI1 6 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_36h DE_36h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_60h DE_60h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 567 bp overlap
ChIP DE DE-FOXA2-2 539 bp overlap
GATA2 4 datasets
Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
GATA4 9 datasets
ChIP DE DE-GATA4-1 530 bp overlap
ChIP DE DE-GATA4-2 606 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 383 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 347 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 309 bp overlap
GATA5 1 dataset
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 17 datasets
ChIP DE DE-GATA6-1 568 bp overlap
ChIP DE DE-GATA6-2 559 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 579 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 408 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 494 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 519 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 561 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 591 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 499 bp overlap
ChIP foregut GSE117136.GATA6.foregut 403 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 283 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 361 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 322 bp overlap
GBX1 1 dataset
Motif DE_36h DE_36h-GBX1_MA0889.2 7 bp overlap
GRHL1 2 datasets
Motif DE_36h DE_36h-GRHL1_MA0647.2 10 bp overlap
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
GSX1 1 dataset
Motif DE_36h DE_36h-GSX1_MA0892.2 6 bp overlap
GSX2 1 dataset
Motif DE_36h DE_36h-GSX2_MA0893.3 7 bp overlap
Gata3 4 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HLF 1 dataset
ChIP HepG2 ENCFF854JLR 70 bp overlap
HOXA1 1 dataset
Motif DE_36h DE_36h-HOXA1_MA1495.2 6 bp overlap
HOXA10 1 dataset
Motif DE_36h DE_36h-HOXA10_MA0899.2 9 bp overlap
HOXA2 1 dataset
Motif DE_36h DE_36h-HOXA2_MA0900.3 6 bp overlap
HOXA3 1 dataset
Motif DE_36h DE_36h-HOXA3_MA2119.1 7 bp overlap
HOXB1 1 dataset
Motif DE_36h DE_36h-HOXB1_MA2093.1 7 bp overlap
HOXB2 1 dataset
Motif DE_36h DE_36h-HOXB2_MA0902.3 6 bp overlap
HOXB3 1 dataset
Motif DE_36h DE_36h-HOXB3_MA0903.2 6 bp overlap
HOXB5 1 dataset
Motif DE_36h DE_36h-HOXB5_MA0904.3 6 bp overlap
HOXC8 1 dataset
Motif DE_36h DE_36h-HOXC8_MA1505.2 6 bp overlap
HOXD3 1 dataset
Motif DE_36h DE_36h-HOXD3_MA0912.2 8 bp overlap
ISX 1 dataset
Motif DE_36h DE_36h-ISX_MA0654.2 6 bp overlap
KLF5 1 dataset
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
LBX1 1 dataset
Motif DE_36h DE_36h-LBX1_MA0618.2 7 bp overlap
LHX5 1 dataset
Motif DE_36h DE_36h-LHX5_MA1519.2 7 bp overlap
LHX6 1 dataset
Motif DE_36h DE_36h-LHX6_MA0658.2 8 bp overlap
LHX9 1 dataset
Motif DE_36h DE_36h-LHX9_MA0701.3 7 bp overlap
LIN54 1 dataset
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
LMX1A 1 dataset
Motif DE_36h DE_36h-LMX1A_MA0702.3 7 bp overlap
LMX1B 1 dataset
Motif DE_36h DE_36h-LMX1B_MA0703.3 8 bp overlap
Lhx1 1 dataset
Motif DE_36h DE_36h-Lhx1_MA1518.3 10 bp overlap
Lhx3 1 dataset
Motif DE_36h DE_36h-Lhx3_MA0135.2 12 bp overlap
Lhx4 1 dataset
Motif DE_36h DE_36h-Lhx4_MA0704.2 6 bp overlap
Lhx8 1 dataset
Motif DE_36h DE_36h-Lhx8_MA0705.2 6 bp overlap
MED1 1 dataset
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 259 bp overlap
MEOX1 1 dataset
Motif DE_36h DE_36h-MEOX1_MA0661.2 7 bp overlap
MEOX2 1 dataset
Motif DE_36h DE_36h-MEOX2_MA0706.2 7 bp overlap
MIXL1 1 dataset
Motif DE_36h DE_36h-MIXL1_MA0662.2 6 bp overlap
MNX1 1 dataset
Motif DE_36h DE_36h-MNX1_MA0707.3 6 bp overlap
MZF1 3 datasets
Motif DE_36h DE_36h-MZF1_MA0056.3 8 bp overlap
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
NFIA 1 dataset
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
NFIC 1 dataset
Motif DE_36h DE_36h-NFIC_MA0161.3 7 bp overlap
NFIX 1 dataset
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
NKX6-1 1 dataset
Motif DE_36h DE_36h-NKX6-1_MA0674.2 7 bp overlap
NKX6-2 1 dataset
Motif DE_36h DE_36h-NKX6-2_MA0675.2 6 bp overlap
NOTO 1 dataset
Motif DE_36h DE_36h-NOTO_MA0710.2 7 bp overlap
PAX4 1 dataset
Motif DE_36h DE_36h-PAX4_MA0068.2 8 bp overlap
PDX1 1 dataset
Motif DE_36h DE_36h-PDX1_MA0132.3 6 bp overlap
PHOX2A 1 dataset
Motif DE_36h DE_36h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 1 dataset
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
POU1F1 1 dataset
Motif DE_36h DE_36h-POU1F1_MA0784.3 14 bp overlap
POU6F1 1 dataset
Motif DE_36h DE_36h-POU6F1_MA0628.2 6 bp overlap
POU6F2 1 dataset
Motif DE_36h DE_36h-POU6F2_MA0793.2 9 bp overlap
PPARD 4 datasets
Motif DE_36h DE_36h-PPARD_MA1550.2 14 bp overlap
Motif DE_48h DE_48h-PPARD_MA1550.2 14 bp overlap
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap
PROP1 1 dataset
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
PRRX1 1 dataset
Motif DE_36h DE_36h-PRRX1_MA0716.2 6 bp overlap
PRRX2 1 dataset
Motif DE_36h DE_36h-PRRX2_MA0075.4 7 bp overlap
Pax7 1 dataset
Motif DE_36h DE_36h-Pax7_MA0680.3 10 bp overlap
Pparg::Rxra 1 dataset
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
RAX2 1 dataset
Motif DE_36h DE_36h-RAX2_MA0717.2 6 bp overlap
RBPJ 3 datasets
Motif DE_36h DE_36h-RBPJ_MA1116.2 6 bp overlap
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap
RXRB 4 datasets
Motif DE_36h DE_36h-RXRB_MA0855.1 14 bp overlap
Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 4 datasets
Motif DE_36h DE_36h-RXRG_MA0856.1 14 bp overlap
Motif DE_48h DE_48h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Runx1 1 dataset
Motif DE_36h DE_36h-Runx1_MA0002.3 9 bp overlap
Rxra 4 datasets
Motif DE_36h DE_36h-Rxra_MA0512.2 14 bp overlap
Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SHOX 1 dataset
Motif DE_36h DE_36h-SHOX_MA0630.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 501 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 305 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 165 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 316 bp overlap
Shox2 1 dataset
Motif DE_36h DE_36h-Shox2_MA0720.2 6 bp overlap
Stat4 1 dataset
Motif DE_60h DE_60h-Stat4_MA0518.2 10 bp overlap
Stat5a::Stat5b 3 datasets
Motif DE_36h DE_36h-Stat5aStat5b_MA0519.2 9 bp overlap
Motif DE_48h DE_48h-Stat5aStat5b_MA0519.2 9 bp overlap
Motif DE_60h DE_60h-Stat5aStat5b_MA0519.2 9 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap
TBR1 4 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap
TBX18 4 datasets
Motif DE_36h DE_36h-TBX18_MA1565.2 9 bp overlap
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap
TBX2 4 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap
TBX21 4 datasets
Motif DE_36h DE_36h-TBX21_MA0690.3 10 bp overlap
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap
TBX3 4 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap
TLX2 1 dataset
Motif DE_36h DE_36h-TLX2_MA1577.2 6 bp overlap
TRPS1 4 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tbx6 4 datasets
Motif DE_36h DE_36h-Tbx6_MA1567.3 9 bp overlap
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap
UNCX 1 dataset
Motif DE_36h DE_36h-UNCX_MA0721.2 6 bp overlap
VAX1 1 dataset
Motif DE_36h DE_36h-VAX1_MA0722.2 7 bp overlap
VAX2 1 dataset
Motif DE_36h DE_36h-VAX2_MA0723.3 6 bp overlap
VSX1 1 dataset
Motif DE_36h DE_36h-VSX1_MA0725.2 7 bp overlap
VSX2 1 dataset
Motif DE_36h DE_36h-VSX2_MA0726.2 7 bp overlap
ZKSCAN2 1 dataset
ChIP HEK293T GSE78099.ZKSCAN2.HEK293T 146 bp overlap
ZNF140 3 datasets
Motif DE_36h DE_36h-ZNF140_MA1589.2 19 bp overlap
Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap
Motif DE_60h DE_60h-ZNF140_MA1589.2 19 bp overlap
ZNF175 1 dataset
ChIP HEK293 GSE76494.ZNF175.HEK293 117 bp overlap
ZNF214 1 dataset
Motif DE_36h DE_36h-ZNF214_MA1975.2 13 bp overlap
ZNF512 1 dataset
ChIP K562 ENCFF601EMZ 99 bp overlap
ZNF530 1 dataset
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
ZNF582 4 datasets
Motif DE_36h DE_36h-ZNF582_MA1983.2 19 bp overlap
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap
Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap
ZNF677 1 dataset
Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap
ZNF682 1 dataset
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
ZNF766 3 datasets
Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
ZNF768 3 datasets
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
Motif DE_48h DE_48h-ZNF768_MA1731.2 9 bp overlap
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
ZNF816 1 dataset
Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap
Zfp809 3 datasets
Motif DE_36h DE_36h-Zfp809_MA2125.1 9 bp overlap
Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap
Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap
mix-a 1 dataset
Motif DE_36h DE_36h-mix-a_MA0621.2 7 bp overlap
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