chr12:8,317,343–8,317,958

chr12 : 8,317,343 – 8,317,958

615 bp 109 TFs 6 linked genes

This 615 bp open chromatin element is linked to 6 target genes and is bound by 109 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000293308		2.3 kb	Proximal	Proximity
LINC00937		73.0 kb	Distal	Multiome
ENSG00000286895		74.6 kb	Distal	Multiome
FAM66C		137.4 kb	Distal	Multiome
NECAP1		235.4 kb	Distal	Multiome
FOXJ2		284.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

109 transcription factors

ARID1B 1 dataset

ChIP K562 ENCFF938UXQ 232 bp overlap

ChIP K562 ENCFF030XBX 207 bp overlap

BARX1 1 dataset

Motif DE_48h DE_48h-BARX1_MA0875.2 6 bp overlap

Motif DE_48h DE_48h-BSX_MA0876.2 6 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 360 bp overlap

CTBP1 1 dataset

ChIP K562 ENCFF403WPG 190 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 345 bp overlap

Motif DE_48h DE_48h-DLX1_MA0879.3 6 bp overlap

Motif DE_48h DE_48h-DLX6_MA0882.2 6 bp overlap

DMBX1 1 dataset

ChIP K562 ENCFF972HXB 217 bp overlap

DMRTA2 1 dataset

Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap

Motif DE_48h DE_48h-Dlx2_MA0885.3 8 bp overlap

Motif DE_48h DE_48h-Dlx3_MA0880.2 6 bp overlap

Motif DE_48h DE_48h-Dlx4_MA0881.2 6 bp overlap

Motif DE_48h DE_48h-Dlx5_MA1476.3 8 bp overlap

ERF::FOXI1 1 dataset

Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap

FOXA1 1 dataset

Motif DE_48h DE_48h-FOXA1_MA0148.5 8 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 615 bp overlap

ChIP DE DE-FOXA2-2 615 bp overlap

Motif DE_48h DE_48h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif DE_48h DE_48h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif DE_48h DE_48h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_48h DE_48h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap

FOXD1 1 dataset

Motif DE_48h DE_48h-FOXD1_MA0031.2 7 bp overlap

FOXD2 1 dataset

Motif DE_48h DE_48h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap

FOXF2 1 dataset

Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap

FOXG1 1 dataset

Motif DE_48h DE_48h-FOXG1_MA0613.1 8 bp overlap

FOXI1 1 dataset

Motif DE_48h DE_48h-FOXI1_MA0042.2 7 bp overlap

FOXK1 1 dataset

Motif DE_48h DE_48h-FOXK1_MA0852.3 7 bp overlap

FOXK2 1 dataset

Motif DE_48h DE_48h-FOXK2_MA1103.3 7 bp overlap

FOXL1 1 dataset

Motif DE_48h DE_48h-FOXL1_MA0033.2 7 bp overlap

FOXO4 1 dataset

Motif DE_48h DE_48h-FOXO4_MA0848.1 7 bp overlap

FOXO6 1 dataset

Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap

FOXP1 1 dataset

Motif DE_48h DE_48h-FOXP1_MA0481.4 7 bp overlap

FOXP2 1 dataset

Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap

FOXP3 1 dataset

Motif DE_48h DE_48h-FOXP3_MA0850.1 7 bp overlap

FOXP4 1 dataset

Motif DE_48h DE_48h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif DE_48h DE_48h-FOXS1_MA2118.1 8 bp overlap

Foxf1 1 dataset

Motif DE_48h DE_48h-Foxf1_MA1606.2 7 bp overlap

Foxj2 1 dataset

Motif DE_48h DE_48h-Foxj2_MA0614.1 8 bp overlap

Foxj3 1 dataset

Motif DE_48h DE_48h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap

Foxo1 1 dataset

Motif DE_48h DE_48h-Foxo1_MA0480.3 7 bp overlap

Foxo3 1 dataset

Motif DE_48h DE_48h-Foxo3_MA0157.4 7 bp overlap

Foxq1 1 dataset

Motif DE_48h DE_48h-Foxq1_MA0040.2 10 bp overlap

GATA1 3 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 55 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 124 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 190 bp overlap

GATA1::TAL1 3 datasets

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 615 bp overlap

ChIP DE DE-GATA4-2 574 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

GATA5 3 datasets

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 9 datasets

ChIP AGS GSE51705.GATA6.AGS 185 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 173 bp overlap

ChIP DE DE-GATA6-1 451 bp overlap

ChIP DE DE-GATA6-2 583 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 435 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 507 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 560 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 603 bp overlap

Motif DE_48h DE_48h-GBX2_MA0890.2 6 bp overlap

Gata3 1 dataset

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HESX1 1 dataset

Motif DE_48h DE_48h-HESX1_MA0894.2 6 bp overlap

HMBOX1 1 dataset

ChIP K562 ENCFF055GAZ 310 bp overlap

HOXA6 1 dataset

Motif DE_48h DE_48h-HOXA6_MA1497.2 7 bp overlap

HOXA7 1 dataset

Motif DE_48h DE_48h-HOXA7_MA1498.3 6 bp overlap

HOXB6 1 dataset

Motif DE_48h DE_48h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_48h DE_48h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_48h DE_48h-HOXB8_MA1502.2 7 bp overlap

HOXD8 1 dataset

Motif DE_48h DE_48h-HOXD8_MA0910.3 7 bp overlap

HOXD9 1 dataset

Motif DE_48h DE_48h-HOXD9_MA0913.3 9 bp overlap

Motif DE_48h DE_48h-Hmx1_MA0896.2 9 bp overlap

Motif DE_48h DE_48h-Hmx2_MA0897.2 15 bp overlap

Motif DE_48h DE_48h-Hmx3_MA0898.2 9 bp overlap

ChIP K562 ENCFF170RNI 262 bp overlap

IKZF1 1 dataset

Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 417 bp overlap

Motif DE_48h DE_48h-LBX2_MA0699.2 6 bp overlap

Motif DE_48h DE_48h-LHX2_MA0700.3 6 bp overlap

Motif DE_48h DE_48h-MSX1_MA0666.3 6 bp overlap

Motif DE_48h DE_48h-MSX2_MA0708.3 6 bp overlap

Mecom 1 dataset

Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap

Motif DE_48h DE_48h-Msx3_MA0709.2 6 bp overlap

NR3C1 1 dataset

ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 74 bp overlap

NR4A1 1 dataset

ChIP K562 ENCFF998LHF 293 bp overlap

NR5A1 1 dataset

Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap

Nobox 1 dataset

Motif DE_48h DE_48h-Nobox_MA0125.2 6 bp overlap

PHOX2A 1 dataset

Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap

Prdm15 2 datasets

Motif DE_48h DE_48h-Prdm15_MA1616.2 11 bp overlap

Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap

Motif DE_48h DE_48h-RAX_MA0718.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 135 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 409 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 585 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 597 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 615 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 615 bp overlap

SMAD3 1 dataset

ChIP K562 ENCFF885DQE 197 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 138 bp overlap

STAT1 1 dataset

Motif DE_48h DE_48h-STAT1_MA0137.4 9 bp overlap

Stat4 1 dataset

Motif DE_48h DE_48h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_48h DE_48h-Stat5a_MA1624.2 9 bp overlap

Stat6 2 datasets

Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap

Motif DE_72h DE_72h-Stat6_MA0520.2 10 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 171 bp overlap

TCF12 1 dataset

ChIP K562 ENCFF931DJY 319 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF465AQA 198 bp overlap

TFCP2 1 dataset

ChIP K562 ENCFF984WXL 238 bp overlap

TRPS1 1 dataset

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

ZBTB17 1 dataset

ChIP K562 ENCFF731UTU 288 bp overlap

ZBTB9 1 dataset

ChIP K562 ENCFF233EFX 249 bp overlap

ChIP K562 ENCFF777OLK 212 bp overlap

ZNF134 1 dataset

ChIP K562 ENCFF502NWS 185 bp overlap

ZNF136 1 dataset

Motif DE_48h DE_48h-ZNF136_MA1588.1 15 bp overlap

ZNF143 1 dataset

Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap

ZNF215 1 dataset

ChIP K562 ENCFF317MOH 145 bp overlap

ZNF257 1 dataset

ChIP K562 ENCFF849YZP 134 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 128 bp overlap

ZNF311 1 dataset

ChIP K562 ENCFF986QSP 174 bp overlap

ZNF317 1 dataset

Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap

ZNF397 1 dataset

ChIP K562 ENCFF203WSD 154 bp overlap

ZNF398 1 dataset

ChIP K562 ENCFF664RQO 167 bp overlap

ZNF583 1 dataset

ChIP K562 ENCFF879KXH 241 bp overlap

ZNF592 1 dataset

ChIP K562 ENCFF547OSS 309 bp overlap