chr11:117,099,458–117,100,103

chr11 : 117,099,458 – 117,100,103

645 bp 62 TFs 11 linked genes

This 645 bp open chromatin element is linked to 11 target genes and is bound by 62 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000224077		472 bp	At TSS	Proximity
SIK3		1.0 kb	Proximal	Proximity
PAFAH1B2		44.4 kb	Distal	Multiome
SIDT2		78.8 kb	Distal	Multiome
TAGLN		99.4 kb	Distal	Multiome
PCSK7		132.1 kb	Distal	Multiome
RNF214		132.8 kb	Distal	Multiome
BACE1-AS		192.2 kb	Distal	Multiome
BACE1		216.3 kb	Distal	Multiome
CEP164		227.9 kb	Distal	Multiome
BUD13		327.0 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

62 transcription factors

ARID1A 2 datasets

ChIP RMG-I GSE120058.ARID1A.RMG-I 71 bp overlap

ChIP RMG-I GSE104545.ARID1A.RMG-I 63 bp overlap

ARID2 1 dataset

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 328 bp overlap

ATF4 2 datasets

Motif DE_48h DE_48h-ATF4_MA0833.3 10 bp overlap

Motif DE_72h DE_72h-ATF4_MA0833.3 10 bp overlap

BCL11A 4 datasets

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 85 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 67 bp overlap

ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 58 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 65 bp overlap

BHLHE22 2 datasets

Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

BRD4 3 datasets

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 500 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 211 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 262 bp overlap

ChIP H1 ENCFF998XEK 107 bp overlap

ChIP 501-mel GSE134848.CHD4.501-mel 156 bp overlap

CREB1 1 dataset

ChIP KG-1_XX65023 GSE74928.CREB1.KG-1_XX65023 195 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 228 bp overlap

ChIP liver ENCFF130MBW 90 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 347 bp overlap

FOXA1 6 datasets

ChIP HepG2 ENCFF740VZW 285 bp overlap

ChIP breast-cancer_Veh-2858 GSE128018.FOXA1.breast-cancer_Veh-2858 105 bp overlap

ChIP breast-cancer_Veh-2860 GSE128018.FOXA1.breast-cancer_Veh-2860 105 bp overlap

ChIP breast_tumor_Female_2 GSE104399.FOXA1.breast_tumor_Female_2 85 bp overlap

ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 168 bp overlap

ChIP primary-breast-cancer_B2_DSG GSE114737.FOXA1.primary-breast-cancer_B2_DSG 130 bp overlap

FOXA2 6 datasets

ChIP DE DE-FOXA2-1 645 bp overlap

ChIP DE DE-FOXA2-2 645 bp overlap

ChIP HepG2 ENCFF533COJ 297 bp overlap

ChIP PANC-1 GSE119930.FOXA2.PANC-1 446 bp overlap

ChIP PANC-1_EV GSE119930.FOXA2.PANC-1_EV 208 bp overlap

ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 331 bp overlap

GATA1 4 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 201 bp overlap

ChIP erythroblast ENCFF867JAR 422 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 453 bp overlap

ChIP erythroid_Don003 GSE137982.GATA1.erythroid_Don003 236 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 562 bp overlap

ChIP DE DE-GATA4-2 645 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 522 bp overlap

ChIP DE DE-GATA6-2 645 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 454 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 442 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 472 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 436 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 594 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 482 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 416 bp overlap

ChIP foregut GSE117136.GATA6.foregut 261 bp overlap

HNF1B 1 dataset

ChIP PANC-1_HNF1B-OE GSE119930.HNF1B.PANC-1_HNF1B-OE 53 bp overlap

Hnf1A 2 datasets

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 391 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 352 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 276 bp overlap

JUND 2 datasets

Motif DE_48h DE_48h-JUND_MA0492.2 11 bp overlap

Motif DE_72h DE_72h-JUND_MA0492.2 11 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 151 bp overlap

Lef1 2 datasets

Motif DE_48h DE_48h-Lef1_MA0768.3 8 bp overlap

Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

Neurod2 2 datasets

Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Olig2 2 datasets

Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 68 bp overlap

POU5F1 1 dataset

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 169 bp overlap

PRDM10 2 datasets

ChIP HEK293 ENCFF145WQQ 312 bp overlap

ChIP K-562 ENCSR120MPG.PRDM10.K-562 160 bp overlap

PSIP1 1 dataset

ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 84 bp overlap

ChIP LTAD_EtOH GSE94577.SFPQ.LTAD_EtOH 154 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 593 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 426 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 376 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 430 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 272 bp overlap

SOX13 1 dataset

Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 248 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 348 bp overlap

SOX2 2 datasets

Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 237 bp overlap

SREBF1 2 datasets

Motif DE_48h DE_48h-SREBF1_MA0829.3 10 bp overlap

Motif DE_72h DE_72h-SREBF1_MA0829.3 10 bp overlap

SREBF2 1 dataset

Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap

SREBP2 1 dataset

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 80 bp overlap

Motif DE_72h DE_72h-Sox1_MA0870.1 15 bp overlap

Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap

ChIP CD34 GSE52924.TAL1.CD34 169 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX5 5 datasets

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

ChIP G296S GSE85628.TBX5.G296S 188 bp overlap

ChIP G296S_2 GSE85628.TBX5.G296S_2 188 bp overlap

ChIP cardiomyocyte GSE85628.TBX5.cardiomyocyte 185 bp overlap

ChIP cardiomyocyte_1 GSE85628.TBX5.cardiomyocyte_1 185 bp overlap

TCF7L1 1 dataset

Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TEAD4 2 datasets

Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

TFAP4 2 datasets

Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap

Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap

Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap

Tcf12 2 datasets

Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Twist2 2 datasets

Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP LNCaP GSE64656.VDR.LNCaP 54 bp overlap

ZNF143 1 dataset

Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap

ZNF263 1 dataset

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 156 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 429 bp overlap

ZNF410 1 dataset

Motif DE_72h DE_72h-ZNF410_MA0752.2 16 bp overlap

ZNF682 2 datasets

Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap

Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap

ZNF76 1 dataset

Motif DE_72h DE_72h-ZNF76_MA1716.2 17 bp overlap

Zfp809 2 datasets

Motif DE_48h DE_48h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap