chr7 : 148,367,810 – 148,368,682

872 bp 103 TFs 1 linked gene

This 872 bp open chromatin element is linked to CNTNAP2 and is bound by 103 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CNTNAP2		28.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ALX3 1 dataset

Motif DE_36h DE_36h-ALX3_MA0634.2 6 bp overlap

ATRX 1 dataset

ChIP metastatic-neuroblastoma_SKNMM GSE100148.ATRX.metastatic-neuroblastoma_SKNMM 707 bp overlap

BRD4 11 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 228 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 205 bp overlap

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 872 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 872 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 228 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 531 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 366 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 836 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 196 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 197 bp overlap

ChIP SK-N-BE2-C_Resistant-veh GSE107706.BRD4.SK-N-BE2-C_Resistant-veh 583 bp overlap

CDK9 2 datasets

ChIP Kelly_CYC065 GSE107126.CDK9.Kelly_CYC065 607 bp overlap

ChIP Kelly_DMSO GSE107126.CDK9.Kelly_DMSO 677 bp overlap

CREM 1 dataset

ChIP GM12878 ENCSR839XZU.CREM.GM12878 101 bp overlap

CTCF 2 datasets

Motif DE_36h DE_36h-CTCF_MA1930.2 33 bp overlap

Motif DE_48h DE_48h-CTCF_MA1929.2 31 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF031ISE 102 bp overlap

Crx 1 dataset

Motif DE_36h DE_36h-Crx_MA0467.3 6 bp overlap

DPRX 1 dataset

Motif DE_36h DE_36h-DPRX_MA1480.2 9 bp overlap

DRGX 1 dataset

Motif DE_36h DE_36h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif DE_36h DE_36h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif DE_36h DE_36h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif DE_36h DE_36h-EN1_MA0027.3 6 bp overlap

EP300 3 datasets

ChIP neural ENCSR843ZUP.EP300.neural 567 bp overlap

ChIP neural cell ENCFF442QNK 284 bp overlap

ChIP neural cell ENCFF442QNK 312 bp overlap

ERG 1 dataset

ChIP aortic-endothelial-cell_D40 GSE139377.ERG.aortic-endothelial-cell_D40 165 bp overlap

EVX1 1 dataset

Motif DE_36h DE_36h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif DE_36h DE_36h-EVX2_MA0888.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 658 bp overlap

ChIP DE DE-FOXA2-2 587 bp overlap

FOXH1 1 dataset

Motif DE_36h DE_36h-FOXH1_MA0479.2 8 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 188 bp overlap

GATA3 1 dataset

ChIP Kelly GSE94822.GATA3.Kelly 421 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 872 bp overlap

ChIP DE DE-GATA4-2 872 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 754 bp overlap

ChIP DE DE-GATA6-2 872 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 509 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 670 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 727 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 568 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 490 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 375 bp overlap

GSC 1 dataset

Motif DE_36h DE_36h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_36h DE_36h-GSC2_MA0891.2 6 bp overlap

GSX1 1 dataset

Motif DE_36h DE_36h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif DE_36h DE_36h-GSX2_MA0893.3 7 bp overlap

HAND2 4 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 546 bp overlap

Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 831 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 688 bp overlap

HOXA1 1 dataset

Motif DE_36h DE_36h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif DE_36h DE_36h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif DE_36h DE_36h-HOXA3_MA2119.1 7 bp overlap

HOXA5 1 dataset

Motif DE_36h DE_36h-HOXA5_MA0158.2 8 bp overlap

HOXA6 1 dataset

Motif DE_36h DE_36h-HOXA6_MA1497.2 7 bp overlap

HOXB1 1 dataset

Motif DE_36h DE_36h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif DE_36h DE_36h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif DE_36h DE_36h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif DE_36h DE_36h-HOXB5_MA0904.3 6 bp overlap

HOXB6 1 dataset

Motif DE_36h DE_36h-HOXB6_MA1500.2 7 bp overlap

HOXB7 1 dataset

Motif DE_36h DE_36h-HOXB7_MA1501.2 7 bp overlap

HOXB8 1 dataset

Motif DE_36h DE_36h-HOXB8_MA1502.2 7 bp overlap

HOXC8 1 dataset

Motif DE_36h DE_36h-HOXC8_MA1505.2 6 bp overlap

HOXD8 1 dataset

Motif DE_36h DE_36h-HOXD8_MA0910.3 7 bp overlap

ISL1 1 dataset

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 456 bp overlap

ISX 1 dataset

Motif DE_36h DE_36h-ISX_MA0654.2 6 bp overlap

KLF1 1 dataset

Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap

KLF14 1 dataset

Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap

KLF2 1 dataset

Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap

KLF4 1 dataset

Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap

KLF5 1 dataset

Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap

LHX5 1 dataset

Motif DE_36h DE_36h-LHX5_MA1519.2 7 bp overlap

Lhx4 1 dataset

Motif DE_36h DE_36h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif DE_36h DE_36h-Lhx8_MA0705.2 6 bp overlap

MEIS1 1 dataset

Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap

MEOX1 1 dataset

Motif DE_36h DE_36h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif DE_36h DE_36h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif DE_36h DE_36h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif DE_36h DE_36h-MNX1_MA0707.3 6 bp overlap

MYB 1 dataset

Motif DE_48h DE_48h-MYB_MA0100.4 6 bp overlap

MYC 1 dataset

ChIP Kelly GSE138295.MYC.Kelly 357 bp overlap

MYCN 2 datasets

ChIP Kelly GSE94822.MYCN.Kelly 634 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 621 bp overlap

NEUROD1 3 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 187 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 212 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 202 bp overlap

NEUROG2 1 dataset

Motif DE_48h DE_48h-NEUROG2_MA1642.2 7 bp overlap

NKX6-2 1 dataset

Motif DE_36h DE_36h-NKX6-2_MA0675.2 6 bp overlap

OTX1 1 dataset

Motif DE_36h DE_36h-OTX1_MA0711.2 6 bp overlap

PATZ1 1 dataset

Motif DE_36h DE_36h-PATZ1_MA1961.2 11 bp overlap

PDX1 1 dataset

Motif DE_36h DE_36h-PDX1_MA0132.3 6 bp overlap

PHOX2B 2 datasets

ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 360 bp overlap

ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 422 bp overlap

PITX1 1 dataset

Motif DE_36h DE_36h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_36h DE_36h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 237 bp overlap

POU1F1 1 dataset

Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap

POU2F2 1 dataset

Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 325 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 340 bp overlap

POU6F1 1 dataset

Motif DE_36h DE_36h-POU6F1_MA0628.2 6 bp overlap

PRDM10 2 datasets

ChIP K-562 ENCSR120MPG.PRDM10.K-562 281 bp overlap

ChIP K562 ENCFF740YLK 417 bp overlap

PRRX1 1 dataset

Motif DE_36h DE_36h-PRRX1_MA0716.2 6 bp overlap

RAD21 1 dataset

ChIP neural ENCSR198ZYJ.RAD21.neural 644 bp overlap

RAX2 1 dataset

Motif DE_36h DE_36h-RAX2_MA0717.2 6 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 575 bp overlap

ChIP neural cell ENCFF882LXX 315 bp overlap

RHOXF1 1 dataset

Motif DE_36h DE_36h-RHOXF1_MA0719.2 6 bp overlap

RREB1 1 dataset

Motif DE_36h DE_36h-RREB1_MA0073.2 19 bp overlap

SHOX 1 dataset

Motif DE_36h DE_36h-SHOX_MA0630.2 6 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 663 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 566 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 272 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 773 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 854 bp overlap

SMARCA4 1 dataset

ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 169 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 157 bp overlap

SMC1A-B 1 dataset

ChIP Kelly_shLUC-res GSE115248.SMC1A-B.Kelly_shLUC-res 153 bp overlap

SMC3 2 datasets

ChIP neural ENCSR404BPV.SMC3.neural 314 bp overlap

ChIP neural cell ENCFF795YGY 451 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 824 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 548 bp overlap

SOX2 1 dataset

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 332 bp overlap

SP8 1 dataset

Motif DE_36h DE_36h-SP8_MA0747.2 11 bp overlap

Shox2 1 dataset

Motif DE_36h DE_36h-Shox2_MA0720.2 6 bp overlap

TBX2 2 datasets

ChIP Kelly GSE94822.TBX2.Kelly 404 bp overlap

ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 334 bp overlap

TLX2 1 dataset

Motif DE_36h DE_36h-TLX2_MA1577.2 6 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 207 bp overlap

UNCX 1 dataset

Motif DE_36h DE_36h-UNCX_MA0721.2 6 bp overlap

VAX2 1 dataset

Motif DE_36h DE_36h-VAX2_MA0723.3 6 bp overlap

ZNF354C 1 dataset

Motif DE_36h DE_36h-ZNF354C_MA0130.1 6 bp overlap

ZNF528 1 dataset

Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap