chr6 : 143,963,283 – 143,963,487
204 bp 59 TFs 1 linked gene
This 204 bp open chromatin element is linked to PLAGL1 and is bound by 59 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PLAGL1 1.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:143,958,283 – 143,968,487
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
59 transcription factors
Source
Cell type
ASH2L 2 datasets
ChIP H1 ENCFF399KAM 85 bp overlap
ChIP H1 ENCFF399KAM 204 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 110 bp overlap
BRD4 2 datasets
ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 138 bp overlap
ChIP hESC GSE33281.BRD4.hESC 61 bp overlap
CTCF 4 datasets
Motif DE_12h DE_12h-CTCF_MA1930.2 33 bp overlap
Motif DE_24h DE_24h-CTCF_MA1930.2 33 bp overlap
Motif ES_0h ES_0h-CTCF_MA1930.2 33 bp overlap
ChIP hESC_D5 GSE116862.CTCF.hESC_D5 103 bp overlap
ELF1 1 dataset
Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap
ESR1 2 datasets
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap
ChIP breast_tumor_Male_14 GSE104399.ESR1.breast_tumor_Male_14 81 bp overlap
ESRRA 3 datasets
Motif DE_12h DE_12h-ESRRA_MA0592.4 9 bp overlap
Motif DE_24h DE_24h-ESRRA_MA0592.4 9 bp overlap
Motif ES_0h ES_0h-ESRRA_MA0592.4 9 bp overlap
ESRRB 3 datasets
Motif DE_12h DE_12h-ESRRB_MA0141.4 10 bp overlap
Motif DE_24h DE_24h-ESRRB_MA0141.4 10 bp overlap
Motif ES_0h ES_0h-ESRRB_MA0141.4 10 bp overlap
EZH2 2 datasets
ChIP GM23338 ENCFF613YON 126 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 79 bp overlap
Erg 1 dataset
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
Esrrg 3 datasets
Motif DE_12h DE_12h-Esrrg_MA0643.2 9 bp overlap
Motif DE_24h DE_24h-Esrrg_MA0643.2 9 bp overlap
Motif ES_0h ES_0h-Esrrg_MA0643.2 9 bp overlap
GABPA 1 dataset
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
GATA4 1 dataset
ChIP DE DE-GATA4-2 148 bp overlap
GATA6 4 datasets
ChIP DE_D1 S14-DE-d1-GATA6-exp1 204 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 204 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 204 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 204 bp overlap
HDAC2 1 dataset
ChIP RH4_Entinostat-6H_bioMerck GSE116344.HDAC2.RH4_Entinostat-6H_bioMerck 142 bp overlap
Ikzf3 1 dataset
Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap
Isl1 1 dataset
Motif DE_12h DE_12h-Isl1_MA1608.2 7 bp overlap
JARID2 2 datasets
ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 198 bp overlap
ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 204 bp overlap
JUN 5 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 204 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 204 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 122 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 98 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 204 bp overlap
MAX 1 dataset
ChIP WA01 ENCSR000EUP.MAX.WA01 150 bp overlap
MITF 3 datasets
Motif DE_12h DE_12h-MITF_MA0620.4 10 bp overlap
Motif DE_24h DE_24h-MITF_MA0620.4 10 bp overlap
Motif ES_0h ES_0h-MITF_MA0620.4 10 bp overlap
MXI1 3 datasets
Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap
Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap
Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap
MYBL1 2 datasets
Motif DE_12h DE_12h-MYBL1_MA0776.1 12 bp overlap
Motif DE_24h DE_24h-MYBL1_MA0776.1 12 bp overlap
NANOG 2 datasets
ChIP WA01 ERP004238.NANOG.WA01 191 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 189 bp overlap
NFIL3 1 dataset
Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap
NR2C1 3 datasets
Motif DE_12h DE_12h-NR2C1_MA1535.2 6 bp overlap
Motif DE_24h DE_24h-NR2C1_MA1535.2 6 bp overlap
Motif ES_0h ES_0h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_12h DE_12h-NR2C2_MA1536.2 6 bp overlap
Motif DE_24h DE_24h-NR2C2_MA1536.2 6 bp overlap
Motif ES_0h ES_0h-NR2C2_MA1536.2 6 bp overlap
NR2F1 3 datasets
Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap
Motif DE_24h DE_24h-NR2F1_MA0017.3 12 bp overlap
Motif ES_0h ES_0h-NR2F1_MA0017.3 12 bp overlap
NR2F2 3 datasets
Motif DE_12h DE_12h-NR2F2_MA1111.2 7 bp overlap
Motif DE_24h DE_24h-NR2F2_MA1111.2 7 bp overlap
Motif ES_0h ES_0h-NR2F2_MA1111.2 7 bp overlap
NR5A1 3 datasets
Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap
Motif DE_24h DE_24h-NR5A1_MA1540.3 12 bp overlap
Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap
Nr1H2 3 datasets
Motif DE_12h DE_12h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_24h DE_24h-Nr1H2_MA1996.2 6 bp overlap
Motif ES_0h ES_0h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 3 datasets
Motif DE_12h DE_12h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_24h DE_24h-Nr1H4_MA1110.3 6 bp overlap
Motif ES_0h ES_0h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 3 datasets
Motif DE_12h DE_12h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_24h DE_24h-Nr1h3_MA2337.1 6 bp overlap
Motif ES_0h ES_0h-Nr1h3_MA2337.1 6 bp overlap
Nr5A2 3 datasets
Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_24h DE_24h-Nr5A2_MA0505.3 9 bp overlap
Motif ES_0h ES_0h-Nr5A2_MA0505.3 9 bp overlap
PRDM14 1 dataset
ChIP hESC GSE138674.PRDM14.hESC 204 bp overlap
Pgr 1 dataset
Motif DE_12h DE_12h-Pgr_MA2323.1 17 bp overlap
Ppara 3 datasets
Motif DE_12h DE_12h-Ppara_MA2338.1 7 bp overlap
Motif DE_24h DE_24h-Ppara_MA2338.1 7 bp overlap
Motif ES_0h ES_0h-Ppara_MA2338.1 7 bp overlap
RNF2 1 dataset
ChIP WA01 ENCSR784VUY.RNF2.WA01 204 bp overlap
RORA 3 datasets
Motif DE_12h DE_12h-RORA_MA0071.1 10 bp overlap
Motif DE_24h DE_24h-RORA_MA0071.1 10 bp overlap
Motif ES_0h ES_0h-RORA_MA0071.1 10 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 199 bp overlap
Runx1 2 datasets
Motif DE_12h DE_12h-Runx1_MA0002.3 9 bp overlap
Motif DE_24h DE_24h-Runx1_MA0002.3 9 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 204 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 204 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 204 bp overlap
SMARCA4 1 dataset
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 114 bp overlap
SMARCC1 1 dataset
ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 204 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 145 bp overlap
SS18 2 datasets
ChIP SYO-1 GSE108025.SS18.SYO-1 73 bp overlap
ChIP SYO-1_shRING1A-B GSE139053.SS18.SYO-1_shRING1A-B 204 bp overlap
SUZ12 1 dataset
ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 86 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 204 bp overlap
TFEB 3 datasets
Motif DE_12h DE_12h-TFEB_MA0692.2 8 bp overlap
Motif DE_24h DE_24h-TFEB_MA0692.2 8 bp overlap
Motif ES_0h ES_0h-TFEB_MA0692.2 8 bp overlap
TFEC 3 datasets
Motif DE_12h DE_12h-TFEC_MA0871.3 8 bp overlap
Motif DE_24h DE_24h-TFEC_MA0871.3 8 bp overlap
Motif ES_0h ES_0h-TFEC_MA0871.3 8 bp overlap
USF1 5 datasets
Motif DE_12h DE_12h-USF1_MA0093.4 10 bp overlap
Motif DE_24h DE_24h-USF1_MA0093.4 10 bp overlap
Motif ES_0h ES_0h-USF1_MA0093.4 10 bp overlap
ChIP H1 ENCFF090WVU 150 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 198 bp overlap
USF2 3 datasets
ChIP H1 ENCFF434EDF 204 bp overlap
ChIP WA01 ENCSR000ECD.USF2.WA01 123 bp overlap
ChIP WTC11 ENCFF139JAW 204 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 129 bp overlap
ZNF205 1 dataset
ChIP HEK293T GSE78099.ZNF205.HEK293T 204 bp overlap
ZNF23 1 dataset
ChIP K-562 ENCSR898IDK.ZNF23.K-562 174 bp overlap
ZNF281 1 dataset
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
ZNF331 1 dataset
Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap
ZNF449 3 datasets
Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap
Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap
Motif ES_0h ES_0h-ZNF449_MA1656.2 10 bp overlap
Huangfu Lab · Publications · Resources · Contact