chr6:3,041,670–3,042,232

chr6 : 3,041,670 – 3,042,232

562 bp 84 TFs 10 linked genes

This 562 bp open chromatin element is linked to 10 target genes and is bound by 84 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RIPK1		21.9 kb	Distal	Multiome
NQO2		53.3 kb	Distal	Multiome
SERPINB6		70.7 kb	Distal	Multiome
BPHL		76.7 kb	Distal	Multiome
TUBB2A		115.6 kb	Distal	Multiome
SERPINB9		138.7 kb	Distal	Multiome
TUBB2B		185.7 kb	Distal	Multiome
PSMG4		189.8 kb	Distal	Multiome
SERPINB1		200.1 kb	Distal	Multiome
WRNIP1		276.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

84 transcription factors

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 482 bp overlap

ASCL1 1 dataset

Motif DE_72h DE_72h-ASCL1_MA1631.2 9 bp overlap

ChIP G-401 GSE120234.BRD9.G-401 254 bp overlap

CBFA2T2 1 dataset

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 207 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 338 bp overlap

ChIP K562 ENCFF673OEZ 257 bp overlap

CEBPB 1 dataset

ChIP K-562 ENCSR000EHE.CEBPB.K-562 145 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 231 bp overlap

ChIP HUVEC-C GSE128382.ERG.HUVEC-C 146 bp overlap

ChIP aortic-endothelial-cell_D5 GSE139377.ERG.aortic-endothelial-cell_D5 147 bp overlap

ChIP T-47D ENCSR000BJS.ESR1.T-47D 114 bp overlap

Motif DE_72h DE_72h-ETV1_MA0761.3 9 bp overlap

EZH2 2 datasets

ChIP neural progenitor cell ENCFF018MKA 562 bp overlap

ChIP neural progenitor cell ENCFF018MKA 306 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 248 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 514 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 562 bp overlap

ChIP DE DE-FOXA2-2 562 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 521 bp overlap

FOXB1 1 dataset

Motif DE_72h DE_72h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_72h DE_72h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_72h DE_72h-FOXC2_MA0846.2 11 bp overlap

FOXD3 1 dataset

Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap

GATA1 2 datasets

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 207 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap

GATA1::TAL1 2 datasets

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 3 datasets

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 310 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 152 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 503 bp overlap

ChIP DE DE-GATA4-2 562 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 444 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 499 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 562 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 562 bp overlap

ChIP DE DE-GATA6-2 562 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 562 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 84 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 562 bp overlap

ChIP foregut GSE117136.GATA6.foregut 334 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 303 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 440 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC2 4 datasets

ChIP K-562 ENCSR000BMG.HDAC2.K-562 189 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 360 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 307 bp overlap

ChIP K562 ENCFF744ALD 344 bp overlap

ChIP HepG2 ENCFF854JLR 191 bp overlap

HMBOX1 1 dataset

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 181 bp overlap

HMGXB4 1 dataset

ChIP Hep-G2 ENCSR174GOO.HMGXB4.Hep-G2 160 bp overlap

HOXB13 1 dataset

ChIP G-401 GSE65381.HOXB13.G-401 141 bp overlap

Hand1 1 dataset

Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

Motif DE_72h DE_72h-IRF2_MA0051.2 16 bp overlap

Ikzf3 1 dataset

Motif DE_72h DE_72h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap

KDM1A 3 datasets

ChIP K-562 ENCSR360HRA.KDM1A.K-562 215 bp overlap

ChIP K-562 ENCSR908CMW.KDM1A.K-562 243 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 492 bp overlap

ChIP THP-1 GSE90769.MYB.THP-1 195 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 288 bp overlap

Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF788MPU 407 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 104 bp overlap

Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap

Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap

POU1F1 1 dataset

Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap

PRDM1 2 datasets

Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap

Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap

Ptf1A 1 dataset

Motif DE_72h DE_72h-Ptf1A_MA1620.2 8 bp overlap

RELA 2 datasets

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 203 bp overlap

ChIP aortic-endothelial-cell_IL1B_D6 GSE139377.RELA.aortic-endothelial-cell_IL1B_D6 177 bp overlap

SMAD2 1 dataset

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 562 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 528 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 250 bp overlap

SNAI1 1 dataset

Motif DE_72h DE_72h-SNAI1_MA1558.2 7 bp overlap

SNAI3 1 dataset

Motif DE_72h DE_72h-SNAI3_MA1559.2 9 bp overlap

SOX10 2 datasets

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 183 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 515 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 263 bp overlap

ChIP K562 ENCFF059YCJ 370 bp overlap

Motif DE_72h DE_72h-SPIC_MA0687.2 13 bp overlap

STAT1::STAT2 1 dataset

Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap

STAT3 2 datasets

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 203 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 353 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Stat2 1 dataset

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

TAL1 2 datasets

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 218 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 192 bp overlap

TCF12 1 dataset

Motif DE_72h DE_72h-TCF12_MA1648.2 7 bp overlap

Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TRPS1 1 dataset

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ZBTB18 1 dataset

Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 323 bp overlap

Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap

ZNF143 1 dataset

ChIP K-562 GSE39263.ZNF143.K-562 189 bp overlap

ZNF175 1 dataset

Motif DE_72h DE_72h-ZNF175_MA2332.1 9 bp overlap

ZNF317 1 dataset

Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap

ZNF547 1 dataset

Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap

ZNF680 1 dataset

Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap

ZNF766 1 dataset

Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap

ZSCAN21 1 dataset

Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap