Predicted to be involved in proteasome assembly. Predicted to be located in cytosol. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for PSMG4. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = PSMG4 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of PSMG4, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr6:2,931,916–2,932,749 | 299.4 kb | Distal (>10kb) Multiome | 652 | |
| chr6:2,942,573–2,943,965 | 288.7 kb | Distal (>10kb) Multiome | 222 | |
| chr6:2,952,443–2,953,210 | 279.0 kb | Distal (>10kb) Multiome | 649 | |
| chr6:2,970,836–2,972,016 | 260.5 kb | Distal (>10kb) Multiome | 817 | |
| chr6:2,985,539–2,987,671 | 245.8 kb | Distal (>10kb) Multiome | 402 | |
| chr6:2,987,802–2,990,098 | 242.0 kb | Distal (>10kb) Multiome | 1173 | |
| chr6:2,990,284–2,991,348 | 240.9 kb | Distal (>10kb) Multiome | 509 | |
| chr6:2,999,131–3,000,475 | 232.0 kb | Distal (>10kb) Multiome | 930 | |
| chr6:3,041,670–3,042,232 | 189.8 kb | Distal (>10kb) Multiome | 84 | |
| chr6:3,052,936–3,054,463 | 178.0 kb | Distal (>10kb) Multiome | 864 | |
| chr6:3,063,662–3,064,609 | 167.9 kb | Distal (>10kb) Multiome | 752 | |
| chr6:3,068,179–3,069,296 | 163.1 kb | Distal (>10kb) Multiome | 1032 | |
| chr6:3,118,061–3,119,380 | 113.2 kb | Distal (>10kb) Multiome HiCAR | 966 | |
| chr6:3,156,701–3,158,249 | 74.2 kb | Distal (>10kb) Multiome HiCAR | 859 | |
| chr6:3,162,506–3,163,526 | 68.8 kb | Distal (>10kb) Multiome HiCAR | 926 | |
| chr6:3,165,678–3,166,637 | 65.4 kb | Distal (>10kb) Multiome HiCAR | 343 | |
| chr6:3,226,566–3,229,919 | 4.0 kb | Proximal (<10kb) Multiome | 770 | |
| chr6:3,231,202–3,232,265 | 42 bp | At TSS Multiome | 593 | |
| chr6:3,239,525–3,239,709 | 7.7 kb | Proximal (<10kb) | 57 | |
| chr6:3,251,328–3,252,273 | 19.9 kb | Distal (>10kb) Multiome | 561 | |
| chr6:3,258,552–3,259,886 | 27.1 kb | Distal (>10kb) Multiome | 946 | |
| chr6:3,356,075–3,356,744 | 124.6 kb | Distal (>10kb) Multiome | 475 | |
| chr6:3,414,872–3,415,397 | 183.3 kb | Distal (>10kb) Multiome | 265 | |
| chr6:3,423,549–3,424,168 | 192.1 kb | Distal (>10kb) Multiome | 107 | |
| chr6:3,455,491–3,458,021 | 225.3 kb | Distal (>10kb) Multiome | 809 | |
| chr6:3,511,478–3,512,074 | 279.9 kb | Distal (>10kb) Multiome | 323 |
Genomic view of the PSMG4 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.