chr5 : 160,485,087 – 160,485,947

860 bp 81 TFs 1 linked gene

This 860 bp open chromatin element is linked to MIR146A and is bound by 81 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
MIR146A		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

AHR 1 dataset

ChIP GM01310_DMSO GSE116632.AHR.GM01310_DMSO 97 bp overlap

ASCL1 2 datasets

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

Motif DE_12h DE_12h-ASCL1_MA1631.2 9 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BACH1 1 dataset

ChIP GM12878 ENCSR636MKU.BACH1.GM12878 265 bp overlap

BCL3 3 datasets

ChIP GM12878 ENCFF854PAY 107 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 297 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 210 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD4 3 datasets

ChIP CHL-1 GSE95585.BRD4.CHL-1 212 bp overlap

ChIP CHL-1 GSE95585.BRD4.CHL-1 333 bp overlap

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 217 bp overlap

CEBPA 3 datasets

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

Motif ES_0h ES_0h-CEBPA_MA0102.5 10 bp overlap

CEBPD 2 datasets

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

Motif ES_0h ES_0h-CEBPD_MA0836.3 8 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 296 bp overlap

ChIP BLaER1 ENCFF274GAT 285 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 374 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 350 bp overlap

ERF::FIGLA 1 dataset

Motif DE_12h DE_12h-ERFFIGLA_MA1934.2 13 bp overlap

ETV1 2 datasets

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

Motif ES_0h ES_0h-ETV1_MA0761.3 9 bp overlap

ETV2::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_12h DE_12h-ETV5FIGLA_MA1945.2 14 bp overlap

EZH2 1 dataset

ChIP LNCaP GSE39459.EZH2.LNCaP 264 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 334 bp overlap

Erg 2 datasets

Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap

Motif ES_0h ES_0h-Erg_MA0474.4 10 bp overlap

Hand1 1 dataset

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

IKZF1 2 datasets

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

Motif ES_0h ES_0h-IKZF1_MA1508.2 8 bp overlap

JUN 2 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 293 bp overlap

JUND 1 dataset

Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap

MAX 1 dataset

ChIP WA01 ENCSR000EUP.MAX.WA01 140 bp overlap

MAZ 1 dataset

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 487 bp overlap

MYOG 1 dataset

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

NANOG 5 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 575 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 224 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 353 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 276 bp overlap

ChIP hESC GSE18292.NANOG.hESC 198 bp overlap

NFATC1 2 datasets

ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 400 bp overlap

ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 163 bp overlap

NFATC3 1 dataset

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 467 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

NHLH2 1 dataset

Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

ONECUT1 4 datasets

ChIP H9 ERP004206.ONECUT1.H9 355 bp overlap

ChIP Hep-G2 ENCSR956OSX.ONECUT1.Hep-G2 188 bp overlap

ChIP HepG2 ENCFF243FIR 341 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 510 bp overlap

ONECUT2 2 datasets

ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 217 bp overlap

ChIP PC-3_normoxia GSE106305.ONECUT2.PC-3_normoxia 294 bp overlap

OSR2 2 datasets

Motif DE_12h DE_12h-OSR2_MA1646.2 8 bp overlap

Motif ES_0h ES_0h-OSR2_MA1646.2 8 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

PAX6 1 dataset

Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap

PBX1 1 dataset

Motif DE_12h DE_12h-PBX1_MA0070.2 9 bp overlap

PHOX2B 2 datasets

Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap

Motif ES_0h ES_0h-PHOX2B_MA0681.3 12 bp overlap

PML 1 dataset

ChIP GM12878 ENCSR000BQM.PML.GM12878 558 bp overlap

POLR2A 11 datasets

ChIP GM12878 ENCFF631ERR 417 bp overlap

ChIP GM12878 ENCFF899QYP 260 bp overlap

ChIP GM12891 ENCFF012SUT 265 bp overlap

ChIP GM12891 ENCFF012SUT 481 bp overlap

ChIP GM12892 ENCFF506PGQ 229 bp overlap

ChIP GM12892 ENCFF506PGQ 457 bp overlap

ChIP GM15510 ENCFF880HVJ 192 bp overlap

ChIP GM18951 ENCFF079KKO 79 bp overlap

ChIP GM19099 ENCFF726IBN 121 bp overlap

ChIP GM19193 ENCFF599VTO 368 bp overlap

ChIP GM19193 ENCFF599VTO 102 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PPARG 1 dataset

Motif DE_12h DE_12h-PPARG_MA0066.2 19 bp overlap

Pou5f1::Sox2 2 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

RAD21 2 datasets

ChIP MDM_-dNS1 GSE103477.RAD21.MDM_-dNS1 160 bp overlap

ChIP MDM_-dNS1 GSE103477.RAD21.MDM_-dNS1 219 bp overlap

RARA 1 dataset

ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 280 bp overlap

RELB 1 dataset

ChIP GM12878 ENCSR387QUV.RELB.GM12878 500 bp overlap

SMAD1 1 dataset

ChIP GM12878 ENCSR813DCK.SMAD1.GM12878 271 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 216 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 305 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 424 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 224 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 178 bp overlap

Stat5a 1 dataset

Motif DE_12h DE_12h-Stat5a_MA1624.2 9 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 299 bp overlap

TBP 1 dataset

ChIP hESC GSE122298.TBP.hESC 161 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 657 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_12h DE_12h-TFAP4ETV1_MA1966.2 13 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

ZNF143 1 dataset

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 148 bp overlap

ZNF175 2 datasets

Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap

Motif ES_0h ES_0h-ZNF175_MA2332.1 9 bp overlap

ZNF24 1 dataset

Motif DE_12h DE_12h-ZNF24_MA1124.1 13 bp overlap

ZNF274 1 dataset

Motif DE_12h DE_12h-ZNF274_MA1592.2 12 bp overlap

ZNF317 2 datasets

Motif DE_12h DE_12h-ZNF317_MA1593.2 8 bp overlap

Motif ES_0h ES_0h-ZNF317_MA1593.2 8 bp overlap

ZNF35 2 datasets

Motif DE_12h DE_12h-ZNF35_MA2333.1 7 bp overlap

Motif ES_0h ES_0h-ZNF35_MA2333.1 7 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 391 bp overlap

ZNF510 2 datasets

ChIP HEK293 ENCFF202BSY 299 bp overlap

ChIP HEK293 ENCSR595FAO.ZNF510.HEK293 300 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF652 1 dataset

Motif DE_12h DE_12h-ZNF652_MA1657.2 9 bp overlap

ZNF687 1 dataset

ChIP GM12878 ENCSR859FDL.ZNF687.GM12878 80 bp overlap

ZNF707 2 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Motif ES_0h ES_0h-ZNF707_MA1715.1 15 bp overlap

ZNF75A 1 dataset

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap

ZNF75D 2 datasets

Motif DE_12h DE_12h-ZNF75D_MA1601.2 12 bp overlap

Motif ES_0h ES_0h-ZNF75D_MA1601.2 12 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap