chr5:126,591,477–126,591,957

chr5 : 126,591,477 – 126,591,957

480 bp 61 TFs 5 linked genes

This 480 bp open chromatin element is linked to 5 target genes and is bound by 61 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ALDH7A1		3.1 kb	Proximal	Proximity
PHAX		9.0 kb	Proximal	Proximity
ENSG00000250602		101.3 kb	Distal	Multiome
GRAMD2B		168.3 kb	Distal	Multiome
LMNB1		185.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

61 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 440 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 480 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 356 bp overlap

BARX2 1 dataset

Motif ES_0h ES_0h-BARX2_MA1471.2 9 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 318 bp overlap

CEBPB 2 datasets

ChIP H1 ENCFF871PTR 261 bp overlap

ChIP WA01 ENCSR000EBV.CEBPB.WA01 230 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 135 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 256 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 127 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 111 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 129 bp overlap

Motif ES_0h ES_0h-DUX4_MA0468.1 11 bp overlap

Motif ES_0h ES_0h-DUXA_MA0884.2 13 bp overlap

Motif ES_0h ES_0h-Dux_MA0611.3 11 bp overlap

ChIP K-562 ENCSR000EWL.E2F4.K-562 132 bp overlap

ESR2 2 datasets

Motif DE_12h DE_12h-ESR2_MA0258.2 15 bp overlap

Motif ES_0h ES_0h-ESR2_MA0258.2 15 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 162 bp overlap

FEZF1 1 dataset

ChIP HEK293 GSE76494.FEZF1.HEK293 160 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 200 bp overlap

GTF2I 1 dataset

ChIP WTC11 ENCFF255XXZ 274 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap

HNF1A 1 dataset

Motif ES_0h ES_0h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif ES_0h ES_0h-HNF1B_MA0153.2 13 bp overlap

KDM1A 1 dataset

ChIP H1 ENCFF696SGD 459 bp overlap

LIN54 1 dataset

Motif ES_0h ES_0h-LIN54_MA0619.2 7 bp overlap

Motif ES_0h ES_0h-Lhx3_MA0135.2 12 bp overlap

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

Msgn1 2 datasets

Motif DE_12h DE_12h-Msgn1_MA1524.3 10 bp overlap

Motif ES_0h ES_0h-Msgn1_MA1524.3 10 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 407 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 343 bp overlap

ChIP hESC GSE18292.NANOG.hESC 102 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 85 bp overlap

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

PARP1 1 dataset

ChIP MCF-10A GSE93038.PARP1.MCF-10A 302 bp overlap

Motif ES_0h ES_0h-PAX3_MA0780.1 10 bp overlap

POLR2A 1 dataset

ChIP H1 ENCFF566JSR 480 bp overlap

POU4F1 1 dataset

Motif ES_0h ES_0h-POU4F1_MA0790.2 12 bp overlap

POU4F3 1 dataset

Motif ES_0h ES_0h-POU4F3_MA0791.2 12 bp overlap

POU5F1 2 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 361 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 159 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

PROP1 1 dataset

Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap

Motif ES_0h ES_0h-Pax7_MA0680.3 10 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 359 bp overlap

RBPJ 3 datasets

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

SMAD2-3 1 dataset

ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 113 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 407 bp overlap

SMARCC1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 258 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 243 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 248 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 198 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 126 bp overlap

TBX18 2 datasets

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap

Motif ES_0h ES_0h-THRA_MA1969.2 18 bp overlap

ZKSCAN3 1 dataset

Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF121 1 dataset

ChIP WTC11 ENCFF291API 291 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF449 1 dataset

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 240 bp overlap

ZNF652 1 dataset

Motif ES_0h ES_0h-ZNF652_MA1657.2 9 bp overlap

ZNF664 2 datasets

ChIP HEK293 ENCFF343XSW 385 bp overlap

ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 428 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 251 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 187 bp overlap

ZSCAN21 1 dataset

Motif ES_0h ES_0h-ZSCAN21_MA2336.1 7 bp overlap