chr4 : 183,075,620 – 183,076,390
770 bp 86 TFs 3 linked genes
This 770 bp open chromatin element is linked to ENSG00000273180, WWC2, and DCTD and is bound by 86 transcription factors.
Linked Genes
3 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000273180 at TSS At TSS Proximity
WWC2 23.4 kb Distal Multiome+HiCAR
DCTD 158.5 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:183,070,620 – 183,081,390
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
ARID4B 1 dataset
ChIP HepG2 ENCFF519OXJ 55 bp overlap
BRF1 1 dataset
ChIP H9_Activin GSE94418.BRF1.H9_Activin 148 bp overlap
CEBPD 1 dataset
ChIP HAEC_IL1b_4h GSE89970.CEBPD.HAEC_IL1b_4h 143 bp overlap
EHF 1 dataset
Motif DE_60h DE_60h-EHF_MA0598.4 9 bp overlap
ELF1 1 dataset
Motif DE_60h DE_60h-ELF1_MA0473.4 9 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 658 bp overlap
ERG 5 datasets
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 177 bp overlap
ChIP aortic-endothelial-cell_D28 GSE139377.ERG.aortic-endothelial-cell_D28 156 bp overlap
ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 199 bp overlap
ChIP aortic-endothelial-cell_D40 GSE139377.ERG.aortic-endothelial-cell_D40 165 bp overlap
ChIP aortic-endothelial-cell_D49 GSE139377.ERG.aortic-endothelial-cell_D49 192 bp overlap
ESRRB 3 datasets
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap
ETV5::FOXO1 2 datasets
Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap
Motif DE_72h DE_72h-ETV5FOXO1_MA1947.2 10 bp overlap
EWSR1-FLI1 3 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 560 bp overlap
ChIP DE DE-FOXA2-2 495 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 754 bp overlap
ChIP DE DE-GATA4-2 770 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 425 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 333 bp overlap
GATA5 1 dataset
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 721 bp overlap
ChIP DE DE-GATA6-2 735 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 479 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 453 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 518 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 642 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 587 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 516 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 674 bp overlap
ChIP foregut GSE117136.GATA6.foregut 460 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 357 bp overlap
GLI3 3 datasets
Motif DE_48h DE_48h-GLI3_MA1491.3 15 bp overlap
Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap
Motif DE_72h DE_72h-GLI3_MA1491.3 15 bp overlap
GLIS1 4 datasets
Motif DE_48h DE_48h-GLIS1_MA0735.2 15 bp overlap
Motif DE_60h DE_60h-GLIS1_MA0735.2 15 bp overlap
Motif DE_72h DE_72h-GLIS1_MA0735.2 15 bp overlap
ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 237 bp overlap
GLIS2 3 datasets
Motif DE_48h DE_48h-GLIS2_MA0736.1 14 bp overlap
Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap
Motif DE_72h DE_72h-GLIS2_MA0736.1 14 bp overlap
GLIS3 3 datasets
Motif DE_48h DE_48h-GLIS3_MA0737.1 14 bp overlap
Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap
Motif DE_72h DE_72h-GLIS3_MA0737.1 14 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HSF1 4 datasets
Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap
Motif DE_60h DE_60h-HSF1_MA0486.2 13 bp overlap
Motif DE_60h DE_60h-HSF1_MA0486.2 13 bp overlap
Motif DE_72h DE_72h-HSF1_MA0486.2 13 bp overlap
HSF2 4 datasets
Motif DE_48h DE_48h-HSF2_MA0770.1 13 bp overlap
Motif DE_60h DE_60h-HSF2_MA0770.1 13 bp overlap
Motif DE_60h DE_60h-HSF2_MA0770.1 13 bp overlap
Motif DE_72h DE_72h-HSF2_MA0770.1 13 bp overlap
HSF4 4 datasets
Motif DE_48h DE_48h-HSF4_MA0771.1 13 bp overlap
Motif DE_60h DE_60h-HSF4_MA0771.1 13 bp overlap
Motif DE_60h DE_60h-HSF4_MA0771.1 13 bp overlap
Motif DE_72h DE_72h-HSF4_MA0771.1 13 bp overlap
Ikzf3 1 dataset
Motif DE_60h DE_60h-Ikzf3_MA1992.2 9 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 438 bp overlap
MEIS2 1 dataset
ChIP K-562 ENCSR851BNE.MEIS2.K-562 114 bp overlap
MTA2 1 dataset
ChIP K-562 ENCSR411UYA.MTA2.K-562 219 bp overlap
Mecom 4 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NANOG 2 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 252 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 372 bp overlap
NR1D1 3 datasets
Motif DE_48h DE_48h-NR1D1_MA1531.2 14 bp overlap
Motif DE_60h DE_60h-NR1D1_MA1531.2 14 bp overlap
Motif DE_72h DE_72h-NR1D1_MA1531.2 14 bp overlap
NR1D2 3 datasets
Motif DE_48h DE_48h-NR1D2_MA1532.2 15 bp overlap
Motif DE_60h DE_60h-NR1D2_MA1532.2 15 bp overlap
Motif DE_72h DE_72h-NR1D2_MA1532.2 15 bp overlap
Nfatc2 1 dataset
Motif DE_60h DE_60h-Nfatc2_MA0152.3 8 bp overlap
PBX2 1 dataset
ChIP K-562 ENCSR263DFP.PBX2.K-562 78 bp overlap
PCBP2 2 datasets
ChIP Hep-G2 ENCSR945NSF.PCBP2.Hep-G2 262 bp overlap
ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 307 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 85 bp overlap
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 208 bp overlap
PKNOX1 1 dataset
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 98 bp overlap
POU5F1 1 dataset
ChIP DE_D1 DED1-OCT4_Batch_II 252 bp overlap
PRDM9 3 datasets
Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap
Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
Prdm15 3 datasets
Motif DE_48h DE_48h-Prdm15_MA1616.2 11 bp overlap
Motif DE_60h DE_60h-Prdm15_MA1616.2 11 bp overlap
Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap
RARA 3 datasets
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
Motif DE_60h DE_60h-RARA_MA0729.1 18 bp overlap
Motif DE_72h DE_72h-RARA_MA0729.1 18 bp overlap
RELA 14 datasets
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 247 bp overlap
ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 254 bp overlap
ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 200 bp overlap
ChIP aortic-endothelial-cell_IL1B_D2 GSE139377.RELA.aortic-endothelial-cell_IL1B_D2 167 bp overlap
ChIP aortic-endothelial-cell_IL1B_D25 GSE139377.RELA.aortic-endothelial-cell_IL1B_D25 152 bp overlap
ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 246 bp overlap
ChIP aortic-endothelial-cell_IL1B_D33 GSE139377.RELA.aortic-endothelial-cell_IL1B_D33 169 bp overlap
ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 317 bp overlap
ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 311 bp overlap
ChIP aortic-endothelial-cell_IL1B_D47 GSE139377.RELA.aortic-endothelial-cell_IL1B_D47 209 bp overlap
ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 135 bp overlap
ChIP aortic-endothelial-cell_IL1B_D6 GSE139377.RELA.aortic-endothelial-cell_IL1B_D6 158 bp overlap
ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 337 bp overlap
ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 209 bp overlap
RELB 1 dataset
Motif DE_60h DE_60h-RELB_MA1117.2 7 bp overlap
RFX2 3 datasets
Motif DE_48h DE_48h-RFX2_MA0600.3 14 bp overlap
Motif DE_60h DE_60h-RFX2_MA0600.3 14 bp overlap
Motif DE_72h DE_72h-RFX2_MA0600.3 14 bp overlap
RFX3 3 datasets
Motif DE_48h DE_48h-RFX3_MA0798.3 16 bp overlap
Motif DE_60h DE_60h-RFX3_MA0798.3 16 bp overlap
Motif DE_72h DE_72h-RFX3_MA0798.3 16 bp overlap
RFX5 3 datasets
Motif DE_48h DE_48h-RFX5_MA0510.3 14 bp overlap
Motif DE_60h DE_60h-RFX5_MA0510.3 14 bp overlap
Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap
SATB1 3 datasets
Motif DE_48h DE_48h-SATB1_MA1963.2 7 bp overlap
Motif DE_60h DE_60h-SATB1_MA1963.2 7 bp overlap
Motif DE_72h DE_72h-SATB1_MA1963.2 7 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 327 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 754 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 609 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 559 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 517 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 528 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 429 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 696 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 624 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 203 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 278 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 355 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 276 bp overlap
SOX13 2 datasets
Motif DE_60h DE_60h-SOX13_MA1120.2 7 bp overlap
Motif DE_72h DE_72h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 367 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 664 bp overlap
SOX2 2 datasets
Motif DE_60h DE_60h-SOX2_MA0143.5 7 bp overlap
Motif DE_72h DE_72h-SOX2_MA0143.5 7 bp overlap
SOX21 3 datasets
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap
Motif DE_72h DE_72h-SOX21_MA0866.1 15 bp overlap
SOX4 2 datasets
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SOX8 2 datasets
Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap
Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap
SOX9 2 datasets
Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap
Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap
SP4 3 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SP5 3 datasets
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap
SRY 2 datasets
Motif DE_60h DE_60h-SRY_MA0084.2 7 bp overlap
Motif DE_72h DE_72h-SRY_MA0084.2 7 bp overlap
STAT1::STAT2 1 dataset
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Sox17 5 datasets
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox3 2 datasets
Motif DE_60h DE_60h-Sox3_MA0514.3 7 bp overlap
Motif DE_72h DE_72h-Sox3_MA0514.3 7 bp overlap
Sox5 2 datasets
Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Sox6 5 datasets
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 5 datasets
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 210 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
VEZF1 3 datasets
Motif DE_48h DE_48h-VEZF1_MA1578.2 6 bp overlap
Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap
Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap
ZBTB11 1 dataset
Motif DE_60h DE_60h-ZBTB11_MA2329.1 9 bp overlap
ZBTB18 3 datasets
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZBTB7A 1 dataset
Motif DE_60h DE_60h-ZBTB7A_MA0750.3 9 bp overlap
ZIC5 3 datasets
Motif DE_48h DE_48h-ZIC5_MA1584.2 15 bp overlap
Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap
Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap
ZKSCAN5 1 dataset
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF143 3 datasets
Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap
Motif DE_60h DE_60h-ZNF143_MA0088.2 16 bp overlap
Motif DE_72h DE_72h-ZNF143_MA0088.2 16 bp overlap
ZNF263 3 datasets
Motif DE_48h DE_48h-ZNF263_MA0528.3 7 bp overlap
Motif DE_60h DE_60h-ZNF263_MA0528.3 7 bp overlap
Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap
ZNF282 1 dataset
Motif DE_60h DE_60h-ZNF282_MA1154.2 15 bp overlap
ZNF320 1 dataset
Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap
ZNF354A 3 datasets
Motif DE_48h DE_48h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_72h DE_72h-ZNF354A_MA1978.2 20 bp overlap
ZNF652 1 dataset
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
ZNF675 2 datasets
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF701 3 datasets
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap
Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap
ZNF740 3 datasets
Motif DE_48h DE_48h-ZNF740_MA0753.3 10 bp overlap
Motif DE_60h DE_60h-ZNF740_MA0753.3 10 bp overlap
Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap
Huangfu Lab · Publications · Resources · Contact