chr4 : 32,624,515 – 32,625,882

1,367 bp 75 TFs 0 linked genes

This 1.4 kb open chromatin element has no linked target genes and is bound by 75 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

75 transcription factors

AR 1 dataset

ChIP 22Rv1 GSE85558.AR.22Rv1 216 bp overlap

ARNTL 1 dataset

ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 199 bp overlap

BRD3 1 dataset

ChIP H-1_DE GSE126661.BRD3.H-1_DE 283 bp overlap

BRD4 4 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 482 bp overlap

ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 268 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 214 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 255 bp overlap

Crx 1 dataset

Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap

E2F1 1 dataset

Motif DE_60h DE_60h-E2F1_MA0024.3 12 bp overlap

EP300 3 datasets

ChIP neural ENCSR843ZUP.EP300.neural 285 bp overlap

ChIP neural cell ENCFF442QNK 282 bp overlap

ChIP upper lobe of left lung ENCFF024QBJ 261 bp overlap

ERF::FOXO1 1 dataset

Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap

ERF::SREBF2 1 dataset

Motif DE_60h DE_60h-ERFSREBF2_MA1939.2 16 bp overlap

ERG 1 dataset

ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 144 bp overlap

FOXA1 1 dataset

ChIP LS180 GSE140533.FOXA1.LS180 68 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 472 bp overlap

ChIP DE DE-FOXA2-2 639 bp overlap

FOXC2 1 dataset

Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap

FOXE1 1 dataset

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

FOXH1 1 dataset

Motif DE_60h DE_60h-FOXH1_MA0479.2 8 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_60h DE_60h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 473 bp overlap

ChIP DE DE-GATA4-2 669 bp overlap

ChIP foregut GSE117136.GATA4.foregut 300 bp overlap

GATA6 5 datasets

ChIP DE DE-GATA6-1 442 bp overlap

ChIP DE DE-GATA6-1 238 bp overlap

ChIP DE DE-GATA6-2 595 bp overlap

ChIP DE DE-GATA6-2 251 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 320 bp overlap

GSC 1 dataset

Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap

GZF1 1 dataset

ChIP HepG2 ENCFF060TLH 585 bp overlap

HAND2 1 dataset

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

HNF1A 1 dataset

Motif DE_60h DE_60h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif DE_60h DE_60h-HNF1B_MA0153.2 13 bp overlap

HNF4A 9 datasets

Motif DE_60h DE_60h-HNF4A_MA0114.5 9 bp overlap

Motif DE_60h DE_60h-HNF4A_MA1494.2 14 bp overlap

ChIP Hep-G2 ERP000209.HNF4A.Hep-G2 159 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 154 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 274 bp overlap

ChIP LoVo_PHASES GSE51290.HNF4A.LoVo_PHASES 251 bp overlap

ChIP liver ENCFF354NRH 405 bp overlap

ChIP liver ERP002306.HNF4A.liver 130 bp overlap

HNF4G 2 datasets

Motif DE_60h DE_60h-HNF4G_MA0484.3 9 bp overlap

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 131 bp overlap

Hnf1A 1 dataset

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

NCOR2 1 dataset

ChIP LS180_125 GSE39277.NCOR2.LS180_125 197 bp overlap

NEUROG2 1 dataset

Motif DE_60h DE_60h-NEUROG2_MA1642.2 7 bp overlap

NFIA 1 dataset

Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap

NFIX 1 dataset

Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap

NFKB1 1 dataset

ChIP MCF10A-Er-Src_TAM GSE115597.NFKB1.MCF10A-Er-Src_TAM 120 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap

Nr2e3 1 dataset

Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap

Nr2f6 1 dataset

Motif DE_60h DE_60h-Nr2f6_MA0677.2 13 bp overlap

OTX1 1 dataset

Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap

PITX1 1 dataset

Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 232 bp overlap

PPARD 1 dataset

Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap

RAD21 2 datasets

ChIP neural ENCSR198ZYJ.RAD21.neural 438 bp overlap

ChIP neural cell ENCFF564MOT 182 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 292 bp overlap

ChIP neural cell ENCFF882LXX 242 bp overlap

RHOXF1 1 dataset

Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap

RXR 1 dataset

ChIP LS180 GSE31939.RXR.LS180 138 bp overlap

RXRB 1 dataset

Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap

RXRG 1 dataset

Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap

Rxra 1 dataset

Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 200 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 991 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 369 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 349 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 453 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 467 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 336 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 221 bp overlap

SMC3 2 datasets

ChIP neural ENCSR404BPV.SMC3.neural 407 bp overlap

ChIP neural cell ENCFF795YGY 276 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 218 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 230 bp overlap

SPI1 1 dataset

ChIP BDMC_donorH GSE128834.SPI1.BDMC_donorH 105 bp overlap

STAT3 2 datasets

ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 236 bp overlap

ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 221 bp overlap

Sox6 1 dataset

Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap

TCF7L1 1 dataset

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

TEAD1 1 dataset

ChIP CCLP1 GSE62272.TEAD1.CCLP1 188 bp overlap

THRB 1 dataset

Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap

VDR 1 dataset

ChIP kidney-cortex GSE129585.VDR.kidney-cortex 286 bp overlap

Yy1 1 dataset

Motif DE_60h DE_60h-Yy1_MA0095.4 8 bp overlap

ZBTB18 1 dataset

Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap

ZBTB6 1 dataset

Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap

ZFP42 1 dataset

Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap

ZNF317 2 datasets

Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap

ZNF331 1 dataset

Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap

ZNF354C 1 dataset

Motif DE_60h DE_60h-ZNF354C_MA0130.1 6 bp overlap

ZNF382 1 dataset

Motif DE_60h DE_60h-ZNF382_MA1594.1 24 bp overlap

ZNF549 1 dataset

Motif DE_60h DE_60h-ZNF549_MA1728.2 8 bp overlap

ZNF667 1 dataset

Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap

ZNF708 1 dataset

Motif DE_60h DE_60h-ZNF708_MA1730.2 9 bp overlap