chr3 : 184,570,404 – 184,570,842

438 bp 83 TFs 1 linked gene

This 438 bp open chromatin element is linked to EPHB3 and is bound by 83 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
EPHB3		8.6 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

AGO1 1 dataset

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 190 bp overlap

AR 1 dataset

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 360 bp overlap

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 268 bp overlap

BCOR 1 dataset

ChIP WA01 GSE104690.BCOR.WA01 401 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 291 bp overlap

BRD4 1 dataset

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 352 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 186 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 309 bp overlap

CTCF 4 datasets

ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 196 bp overlap

ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 236 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 94 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 174 bp overlap

ESR1 8 datasets

ChIP Ishikawa_DMSO GSE132426.ESR1.Ishikawa_DMSO 189 bp overlap

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 282 bp overlap

ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 186 bp overlap

ChIP U2OS_100nM-E2 GSE151039.ESR1.U2OS_100nM-E2 325 bp overlap

ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 327 bp overlap

ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 333 bp overlap

ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 307 bp overlap

ChIP VCaP_E2_ERA GSE43985.ESR1.VCaP_E2_ERA 207 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 197 bp overlap

EZH2 4 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 388 bp overlap

ChIP DND41 ENCSR000ASW.EZH2.DND41 168 bp overlap

ChIP neural progenitor cell ENCFF018MKA 438 bp overlap

ChIP neural_progenitor ENCSR069DPL.EZH2.neural_progenitor 306 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 231 bp overlap

FEZF2 1 dataset

Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap

FLI1 1 dataset

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 123 bp overlap

FOS 1 dataset

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 438 bp overlap

GATA4 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 283 bp overlap

GATA6 1 dataset

ChIP DE DE-GATA6-2 310 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 419 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 249 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 179 bp overlap

HOXB4 1 dataset

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

Hand1 1 dataset

Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap

Hnf1A 1 dataset

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

INSM1 1 dataset

Motif DE_72h DE_72h-INSM1_MA0155.1 12 bp overlap

JARID2 3 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 366 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 438 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 303 bp overlap

KDM1A 3 datasets

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 136 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 65 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 236 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 248 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 266 bp overlap

NKX6-1 1 dataset

Motif DE_72h DE_72h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_72h DE_72h-NKX6-3_MA1530.2 8 bp overlap

NR1D1 1 dataset

Motif DE_72h DE_72h-NR1D1_MA1531.2 14 bp overlap

NR1D2 1 dataset

Motif DE_72h DE_72h-NR1D2_MA1532.2 15 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 303 bp overlap

POU5F1 1 dataset

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 235 bp overlap

POU6F1 1 dataset

Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 380 bp overlap

Pparg::Rxra 1 dataset

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

RAD21 1 dataset

ChIP HAP1 GSE152721.RAD21.HAP1 305 bp overlap

RBPJ 1 dataset

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

RNF2 1 dataset

ChIP WA01 ENCSR784VUY.RNF2.WA01 271 bp overlap

RXR 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.RXR.pancreatic-progenitor_PP1 254 bp overlap

SMAD2 1 dataset

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 332 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 367 bp overlap

SOX10 2 datasets

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 341 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 370 bp overlap

SOX2 5 datasets

ChIP H9 GSE46837.SOX2.H9 317 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 281 bp overlap

ChIP hiPSC GSE67282.SOX2.hiPSC 261 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 238 bp overlap

ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 283 bp overlap

SOX21 1 dataset

ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 438 bp overlap

SOX3 1 dataset

ChIP NPC GSE122631.SOX3.NPC 213 bp overlap

SOX4 1 dataset

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

SP5 1 dataset

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 238 bp overlap

SRSF3 1 dataset

ChIP Hep-G2 GSE120104.SRSF3.Hep-G2 245 bp overlap

STAT1 1 dataset

Motif DE_72h DE_72h-STAT1_MA0137.4 9 bp overlap

STAT3 1 dataset

Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap

SUZ12 1 dataset

ChIP Karpas-422_CPI360-D8 GSE134136.SUZ12.Karpas-422_CPI360-D8 268 bp overlap

Sox11 2 datasets

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

Stat5b 1 dataset

Motif DE_72h DE_72h-Stat5b_MA1625.2 9 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 235 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 242 bp overlap

TAL1 1 dataset

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 165 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 56 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 220 bp overlap

THRA 1 dataset

Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap

ZBTB12 1 dataset

Motif DE_72h DE_72h-ZBTB12_MA1649.2 7 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 350 bp overlap

ZFX 2 datasets

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 314 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 287 bp overlap

ZNF213 1 dataset

Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap

ZNF257 2 datasets

Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap

ZNF460 1 dataset

Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap

ZNF530 1 dataset

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF682 1 dataset

Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap

ZNF708 1 dataset

Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 178 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap

Zfx 2 datasets

Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap