chr2 : 222,871,322 – 222,871,781

459 bp 80 TFs 1 linked gene

This 459 bp open chromatin element is linked to ACSL3 and is bound by 80 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ACSL3		9.7 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

AKAP8 1 dataset

ChIP HepG2 ENCFF478OVI 459 bp overlap

AR 1 dataset

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 314 bp overlap

ATOH7 2 datasets

Motif DE_12h DE_12h-ATOH7_MA1468.1 10 bp overlap

Motif DE_36h DE_36h-ATOH7_MA1468.1 10 bp overlap

BHLHE22 1 dataset

Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap

BRD4 1 dataset

ChIP K-562_iBET GSE138084.BRD4.K-562_iBET 233 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 359 bp overlap

EGR1 1 dataset

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 201 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 175 bp overlap

ESR1 1 dataset

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 211 bp overlap

ESR1_pS118 1 dataset

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 459 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif DE_36h DE_36h-FEZF2_MA2341.1 8 bp overlap

FOS 1 dataset

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 459 bp overlap

FOXA2 3 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 121 bp overlap

ChIP DE DE-FOXA2-1 309 bp overlap

ChIP DE DE-FOXA2-2 337 bp overlap

FOXP1 1 dataset

ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 142 bp overlap

GATA1 1 dataset

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 55 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 390 bp overlap

ChIP DE DE-GATA4-2 343 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 259 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 388 bp overlap

ChIP DE DE-GATA6-2 368 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 273 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 362 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 332 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 398 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 324 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 183 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 124 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 398 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 189 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 193 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMSO GSE85096.HIF1A.U2OS_trough_DMSO 237 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 249 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 186 bp overlap

Hmx2 1 dataset

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 333 bp overlap

JUND 1 dataset

Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

MAX 1 dataset

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 141 bp overlap

MXI1 2 datasets

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 329 bp overlap

MYC 1 dataset

ChIP P493-6_Dpy30-shRNA GSE101853.MYC.P493-6_Dpy30-shRNA 191 bp overlap

MYOD1 1 dataset

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 154 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 233 bp overlap

NEUROG1 2 datasets

Motif DE_12h DE_12h-NEUROG1_MA0623.2 10 bp overlap

Motif DE_36h DE_36h-NEUROG1_MA0623.2 10 bp overlap

NEUROG2 2 datasets

Motif DE_12h DE_12h-NEUROG2_MA0669.1 10 bp overlap

Motif DE_36h DE_36h-NEUROG2_MA0669.1 10 bp overlap

Neurod2 1 dataset

Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap

PAF1 2 datasets

ChIP HepG2 ENCFF949UAN 377 bp overlap

ChIP HepG2 ENCFF949UAN 131 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 166 bp overlap

PCBP2 2 datasets

ChIP Hep-G2 ENCSR945NSF.PCBP2.Hep-G2 200 bp overlap

ChIP Hep-G2 GSE120104.PCBP2.Hep-G2 199 bp overlap

PLAGL2 1 dataset

Motif DE_12h DE_12h-PLAGL2_MA1548.2 8 bp overlap

PPARG 1 dataset

ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 198 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 63 bp overlap

RBM22 1 dataset

ChIP HepG2 ENCFF292RVQ 459 bp overlap

SMAD1 1 dataset

ChIP Hep-G2 ENCSR213QOZ.SMAD1.Hep-G2 221 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 246 bp overlap

SMAD3 1 dataset

ChIP Hep-G2 ENCSR005GZH.SMAD3.Hep-G2 257 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 221 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 165 bp overlap

SOX13 1 dataset

ChIP HepG2 ENCFF062VSQ 161 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 322 bp overlap

SOX5 1 dataset

ChIP HepG2 ENCFF470KZD 365 bp overlap

SOX6 2 datasets

ChIP Hep-G2 ENCSR766TSU.SOX6.Hep-G2 393 bp overlap

ChIP HepG2 ENCFF767OCK 196 bp overlap

SP4 1 dataset

ChIP HepG2 ENCFF865DSQ 459 bp overlap

SP5 2 datasets

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap

SPI1 1 dataset

ChIP primary-neutrophil_donorF GSE128834.SPI1.primary-neutrophil_donorF 106 bp overlap

SSRP1 1 dataset

ChIP Hep-G2 ENCSR571PDN.SSRP1.Hep-G2 143 bp overlap

SUPT5H 2 datasets

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 247 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 114 bp overlap

Smad4 1 dataset

Motif DE_12h DE_12h-Smad4_MA1153.2 7 bp overlap

Sox6 1 dataset

Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap

TAL1 1 dataset

ChIP ProEs GSE59087.TAL1.ProEs 191 bp overlap

TBX19 2 datasets

Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap

Motif DE_36h DE_36h-TBX19_MA0804.2 17 bp overlap

TBX2 2 datasets

ChIP Hep-G2 ENCSR410FEH.TBX2.Hep-G2 196 bp overlap

ChIP HepG2 ENCFF811TLA 459 bp overlap

TBXT 2 datasets

Motif DE_12h DE_12h-TBXT_MA0009.2 16 bp overlap

Motif DE_36h DE_36h-TBXT_MA0009.2 16 bp overlap

TFAP4 3 datasets

Motif DE_12h DE_12h-TFAP4_MA1570.1 10 bp overlap

Motif DE_36h DE_36h-TFAP4_MA1570.1 10 bp overlap

ChIP HepG2 ENCFF932XOY 397 bp overlap

Tcf12 1 dataset

Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap

YY1 1 dataset

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 212 bp overlap

ZBTB18 2 datasets

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

Motif DE_36h DE_36h-ZBTB18_MA0698.2 11 bp overlap

ZBTB24 2 datasets

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap

ZNF146 1 dataset

ChIP HepG2 ENCFF383YDA 427 bp overlap

ZNF263 1 dataset

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 133 bp overlap

ZNF324 2 datasets

Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap

Motif DE_36h DE_36h-ZNF324_MA1977.2 14 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 188 bp overlap

ZNF41 2 datasets

ChIP HEK293 GSE76494.ZNF41.HEK293 155 bp overlap

ChIP K-562 ENCSR235PYI.ZNF41.K-562 206 bp overlap

ZNF543 2 datasets

ChIP HepG2 ENCFF864SAR 53 bp overlap

ChIP HepG2 ENCFF864SAR 459 bp overlap

ZNF691 1 dataset

ChIP HepG2 ENCFF427OHT 423 bp overlap

ZNF692 1 dataset

Motif DE_12h DE_12h-ZNF692_MA1986.2 8 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 162 bp overlap

ZSCAN21 1 dataset

Motif DE_12h DE_12h-ZSCAN21_MA2336.1 7 bp overlap

ZSCAN31 1 dataset

Motif DE_36h DE_36h-ZSCAN31_MA1722.2 18 bp overlap

Zfx 2 datasets

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap

Motif DE_36h DE_36h-Zfx_MA0146.3 10 bp overlap