chr2:207,681,149–207,682,035

chr2 : 207,681,149 – 207,682,035

886 bp 73 TFs 7 linked genes

This 886 bp open chromatin element is linked to 7 target genes and is bound by 73 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PPP1R14BP2		at TSS	At TSS	Proximity
CCNYL1		29.9 kb	Distal	Multiome
METTL21A		56.2 kb	Distal	Multiome
ENSG00000272851		72.8 kb	Distal	Multiome
FZD5		88.3 kb	Distal	Multiome
CREB1		151.7 kb	Distal	Multiome
ENSG00000223725		151.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

73 transcription factors

ASCL1 3 datasets

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

Motif DE_24h DE_24h-ASCL1_MA1100.3 8 bp overlap

Motif DE_36h DE_36h-ASCL1_MA1100.3 8 bp overlap

Ahr::Arnt 3 datasets

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_36h DE_36h-AhrArnt_MA0006.2 5 bp overlap

Ascl2 3 datasets

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

Motif DE_24h DE_24h-Ascl2_MA0816.1 10 bp overlap

Motif DE_36h DE_36h-Ascl2_MA0816.1 10 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 391 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 409 bp overlap

BHLHE22 3 datasets

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap

BRD4 2 datasets

ChIP MCF-10A ERP003925.BRD4.MCF-10A 265 bp overlap

ChIP hESC GSE33281.BRD4.hESC 188 bp overlap

Bhlha15 3 datasets

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

Motif DE_24h DE_24h-Bhlha15_MA1472.3 8 bp overlap

Motif DE_36h DE_36h-Bhlha15_MA1472.3 8 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 148 bp overlap

Cebpa 5 datasets

ChIP BLaER1 ENCFF031ISE 251 bp overlap

ChIP BLaER1 ENCFF262VBH 275 bp overlap

ChIP BLaER1 ENCFF274GAT 65 bp overlap

ChIP BLaER1 ENCFF364PUR 472 bp overlap

ChIP BLaER1 ENCFF460KDD 230 bp overlap

ChIP WA01 GSE94322.DUX4.WA01 324 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 451 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 407 bp overlap

KDM4A 3 datasets

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 215 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 197 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 257 bp overlap

KLF1 3 datasets

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap

KLF10 3 datasets

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

Motif DE_36h DE_36h-KLF10_MA1511.2 9 bp overlap

KLF11 3 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap

Motif DE_36h DE_36h-KLF11_MA1512.2 10 bp overlap

KLF12 3 datasets

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

Motif DE_24h DE_24h-KLF12_MA0742.2 9 bp overlap

Motif DE_36h DE_36h-KLF12_MA0742.2 9 bp overlap

KLF13 3 datasets

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

Motif DE_24h DE_24h-KLF13_MA0657.2 17 bp overlap

Motif DE_36h DE_36h-KLF13_MA0657.2 17 bp overlap

KLF14 3 datasets

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_36h DE_36h-KLF14_MA0740.2 9 bp overlap

KLF16 3 datasets

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

Motif DE_36h DE_36h-KLF16_MA0741.1 11 bp overlap

KLF2 3 datasets

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap

KLF3 4 datasets

Motif DE_12h DE_12h-KLF3_MA1516.2 10 bp overlap

Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap

Motif DE_36h DE_36h-KLF3_MA1516.2 10 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 291 bp overlap

KLF5 3 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap

KLF6 3 datasets

Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap

Motif DE_24h DE_24h-KLF6_MA1517.2 9 bp overlap

Motif DE_36h DE_36h-KLF6_MA1517.2 9 bp overlap

KLF7 3 datasets

Motif DE_12h DE_12h-KLF7_MA1959.2 8 bp overlap

Motif DE_24h DE_24h-KLF7_MA1959.2 8 bp overlap

Motif DE_36h DE_36h-KLF7_MA1959.2 8 bp overlap

KLF9 3 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap

Motif DE_36h DE_36h-KLF9_MA1107.3 11 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP WTC11 ENCFF223QFY 489 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 200 bp overlap

ChIP MCF-7_SHRARS GSE60270.MED1.MCF-7_SHRARS 168 bp overlap

MYF5 3 datasets

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

Motif DE_24h DE_24h-MYF5_MA1641.2 8 bp overlap

Motif DE_36h DE_36h-MYF5_MA1641.2 8 bp overlap

MYOD1 3 datasets

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

Motif DE_24h DE_24h-MYOD1_MA0499.3 9 bp overlap

Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap

MYOG 3 datasets

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

Motif DE_24h DE_24h-MYOG_MA0500.3 8 bp overlap

Motif DE_36h DE_36h-MYOG_MA0500.3 8 bp overlap

Mecom 1 dataset

Motif ES_0h ES_0h-Mecom_MA0029.2 11 bp overlap

ChIP erythroid_R3R4 GSE43625.NFE2.erythroid_R3R4 78 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 381 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 428 bp overlap

Neurod2 3 datasets

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap

Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap

Olig2 3 datasets

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap

Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap

PLAG1 1 dataset

Motif DE_12h DE_12h-PLAG1_MA0163.1 14 bp overlap

POU5F1 3 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 106 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 885 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 208 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 690 bp overlap

Ptf1A 3 datasets

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_24h DE_24h-Ptf1A_MA1619.2 8 bp overlap

Motif DE_36h DE_36h-Ptf1A_MA1619.2 8 bp overlap

RAD21 1 dataset

ChIP hiPSC_CVI GSE106870.RAD21.hiPSC_CVI 154 bp overlap

REST 2 datasets

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

Motif DE_24h DE_24h-REST_MA0138.3 20 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 558 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 423 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 471 bp overlap

SOX21 1 dataset

Motif ES_0h ES_0h-SOX21_MA0866.1 15 bp overlap

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_36h DE_36h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

Motif DE_24h DE_24h-SP4_MA0685.2 9 bp overlap

Motif DE_36h DE_36h-SP4_MA0685.2 9 bp overlap

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

Motif DE_24h DE_24h-SP8_MA0747.2 11 bp overlap

Motif DE_36h DE_36h-SP8_MA0747.2 11 bp overlap

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif DE_24h DE_24h-SP9_MA1564.2 10 bp overlap

Motif DE_36h DE_36h-SP9_MA1564.2 10 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 482 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 471 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 266 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 266 bp overlap

THAP1 2 datasets

Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap

Motif DE_24h DE_24h-THAP1_MA0597.3 8 bp overlap

TP63 2 datasets

ChIP keratinocyte GSE33571.TP63.keratinocyte 240 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 141 bp overlap

Tcf12 3 datasets

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap

Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap

Twist2 3 datasets

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap

Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap

USF1 4 datasets

ChIP GM12878 ENCFF880HJL 257 bp overlap

ChIP GM12878 ENCSR000BGI.USF1.GM12878 129 bp overlap

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 213 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

VEZF1 2 datasets

Motif DE_12h DE_12h-VEZF1_MA1578.2 6 bp overlap

Motif DE_24h DE_24h-VEZF1_MA1578.2 6 bp overlap

ChIP GM12878 ENCFF908JTL 345 bp overlap

ChIP GM12891 ENCSR000BKJ.YY1.GM12891 196 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 174 bp overlap

Motif DE_12h DE_12h-YY2_MA0748.3 7 bp overlap

ZBTB24 5 datasets

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_24h DE_24h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_24h DE_24h-ZBTB24_MA2330.1 10 bp overlap

Motif DE_36h DE_36h-ZBTB24_MA2330.1 10 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF427SDV 505 bp overlap

ZFP36 1 dataset

ChIP GM12878 ENCSR900XDB.ZFP36.GM12878 199 bp overlap

ZIC1 3 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif DE_24h DE_24h-ZIC1_MA0696.1 14 bp overlap

Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap

ZNF213 2 datasets

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

Motif DE_24h DE_24h-ZNF213_MA2121.1 12 bp overlap

ZNF320 2 datasets

Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap

Motif DE_24h DE_24h-ZNF320_MA1976.2 20 bp overlap

ZNF331 2 datasets

Motif DE_12h DE_12h-ZNF331_MA1726.2 10 bp overlap

Motif DE_24h DE_24h-ZNF331_MA1726.2 10 bp overlap

ZNF530 3 datasets

Motif DE_12h DE_12h-ZNF530_MA1981.2 14 bp overlap

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

Motif DE_36h DE_36h-ZNF530_MA1981.2 14 bp overlap

ZNF549 3 datasets

Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap

Motif DE_24h DE_24h-ZNF549_MA1728.2 8 bp overlap

Motif DE_36h DE_36h-ZNF549_MA1728.2 8 bp overlap

ZNF682 3 datasets

Motif DE_12h DE_12h-ZNF682_MA1599.2 11 bp overlap

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap

ZNF92 1 dataset

ChIP retina_pigment GSE60024.ZNF92.retina_pigment 298 bp overlap