chr2 : 186,591,929 – 186,592,427

498 bp 77 TFs 1 linked gene

This 498 bp open chromatin element is linked to ITGAV and is bound by 77 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ITGAV		1.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

77 transcription factors

ARID1A 1 dataset

ChIP 12Z GSE129781.ARID1A.12Z 149 bp overlap

ARID2 1 dataset

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 268 bp overlap

ATF3 1 dataset

ChIP K562 ENCFF921JQW 103 bp overlap

CTBP1 1 dataset

ChIP HEK293T ENCFF003PDY 217 bp overlap

Crx 1 dataset

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

DDX5 1 dataset

ChIP NTERA2 GSE58641.DDX5.NTERA2 243 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FOSL1 1 dataset

ChIP K562 ENCFF455MKD 100 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_CDT1 GSE92491.FOXA2.BJ1-hTERT_CDT1 60 bp overlap

GATA2 6 datasets

ChIP ESF GSE108408.GATA2.ESF 182 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 139 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 129 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 171 bp overlap

ChIP primary-endometrial-stromal-cell_Veh_P1 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P1 216 bp overlap

ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 110 bp overlap

GATA3 1 dataset

ChIP MCF-7 GSE122847.GATA3.MCF-7 139 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 498 bp overlap

ChIP DE DE-GATA4-2 498 bp overlap

ChIP G296S GSE85628.GATA4.G296S 155 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 170 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 176 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 84 bp overlap

ChIP foregut GSE117136.GATA4.foregut 451 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 335 bp overlap

ChIP DE DE-GATA6-2 438 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 489 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 498 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 498 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 429 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 349 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 382 bp overlap

ChIP foregut GSE117136.GATA6.foregut 318 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 222 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 265 bp overlap

GSC 1 dataset

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 262 bp overlap

HDGF 1 dataset

ChIP K-562 ENCSR197ALX.HDGF.K-562 270 bp overlap

HOXB8 2 datasets

ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 93 bp overlap

ChIP PANC-1 GSE119930.HOXB8.PANC-1 178 bp overlap

KDM5B 1 dataset

ChIP K562 ENCFF049WWX 356 bp overlap

KMT2A 2 datasets

ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 339 bp overlap

ChIP HEK293T_N-term_shCtrl_TASP1-KO GSE90762.KMT2A.HEK293T_N-term_shCtrl_TASP1-KO 81 bp overlap

MEN1 2 datasets

ChIP MCF-7_E2 GSE85317.MEN1.MCF-7_E2 498 bp overlap

ChIP PC-3 GSE132827.MEN1.PC-3 153 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 498 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 181 bp overlap

NR2F1 1 dataset

ChIP neuron-progenitor GSE132965.NR2F1.neuron-progenitor 208 bp overlap

NRF1 2 datasets

ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 214 bp overlap

ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 135 bp overlap

OTX1 1 dataset

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

PHIP 1 dataset

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 66 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

PKNOX2 1 dataset

Motif DE_12h DE_12h-PKNOX2_MA0783.1 12 bp overlap

POU5F1 1 dataset

ChIP HUES-8 GSE109524.POU5F1.HUES-8 416 bp overlap

PRDM10 3 datasets

ChIP HEK293 ENCFF145WQQ 222 bp overlap

ChIP K-562 ENCSR120MPG.PRDM10.K-562 239 bp overlap

ChIP K562 ENCFF740YLK 417 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 189 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RBFOX2 1 dataset

ChIP HepG2 ENCFF939HTZ 296 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 429 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 255 bp overlap

SMARCA4 2 datasets

ChIP A-549_AG15685 GSE132290.SMARCA4.A-549_AG15685 66 bp overlap

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 158 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 304 bp overlap

SNAI2 1 dataset

Motif DE_12h DE_12h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

TEAD1 1 dataset

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 396 bp overlap

TGIF1 1 dataset

Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

Yy1 1 dataset

Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZBTB24 1 dataset

Motif DE_12h DE_12h-ZBTB24_MA2330.1 10 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 235 bp overlap

ZNF135 1 dataset

Motif DE_12h DE_12h-ZNF135_MA1587.1 14 bp overlap

ZNF2 1 dataset

ChIP HEK293 ENCSR011CKE.ZNF2.HEK293 162 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR695EQB.ZNF24.K-562 155 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF426 1 dataset

ChIP HEK293 ENCSR224NFP.ZNF426.HEK293 263 bp overlap

ZNF449 1 dataset

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ZNF460 2 datasets

Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap

ChIP HepG2 ENCFF007NNM 336 bp overlap

ZNF675 1 dataset

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

ZNF770 5 datasets

ChIP HEK293 ENCFF468FCG 246 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 237 bp overlap

ChIP HEK293 GSE76494.ZNF770.HEK293 113 bp overlap

ChIP Hep-G2 ENCSR510GKB.ZNF770.Hep-G2 218 bp overlap

ChIP HepG2 ENCFF233UVH 358 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap

Znf423 1 dataset

Motif DE_12h DE_12h-Znf423_MA0116.1 15 bp overlap