chr18 : 44,706,619 – 44,707,198
579 bp 85 TFs 1 linked gene
This 579 bp open chromatin element is linked to SETBP1 and is bound by 85 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SETBP1 9.5 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:44,701,619 – 44,712,198
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
85 transcription factors
Source
Cell type
AHR 4 datasets
ChIP MCF-7_DMSO_1d GSE90550.AHR.MCF-7_DMSO_1d 167 bp overlap
ChIP MCF-7_DMSO_45min GSE90550.AHR.MCF-7_DMSO_45min 214 bp overlap
ChIP MCF-7_TCDD_1d GSE90550.AHR.MCF-7_TCDD_1d 274 bp overlap
ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 481 bp overlap
AR 4 datasets
ChIP LNCaP_ETOH GSE69043.AR.LNCaP_ETOH 159 bp overlap
ChIP LNCaP_R1881 GSE69043.AR.LNCaP_R1881 140 bp overlap
ChIP LNCaP_SHGATA2_ETOH GSE69043.AR.LNCaP_SHGATA2_ETOH 156 bp overlap
ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 197 bp overlap
ARID1A 1 dataset
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 340 bp overlap
Atf3 2 datasets
Motif DE_36h DE_36h-Atf3_MA1988.2 7 bp overlap
Motif DE_60h DE_60h-Atf3_MA1988.2 7 bp overlap
BACH1 2 datasets
Motif DE_36h DE_36h-BACH1_MA1633.2 9 bp overlap
Motif DE_60h DE_60h-BACH1_MA1633.2 9 bp overlap
BACH2 2 datasets
Motif DE_36h DE_36h-BACH2_MA1101.3 11 bp overlap
Motif DE_60h DE_60h-BACH2_MA1101.3 11 bp overlap
BATF 2 datasets
Motif DE_36h DE_36h-BATF_MA1634.2 7 bp overlap
Motif DE_60h DE_60h-BATF_MA1634.2 7 bp overlap
BATF3 2 datasets
Motif DE_36h DE_36h-BATF3_MA0835.3 7 bp overlap
Motif DE_60h DE_60h-BATF3_MA0835.3 7 bp overlap
BATF::JUN 2 datasets
Motif DE_36h DE_36h-BATFJUN_MA0462.3 7 bp overlap
Motif DE_60h DE_60h-BATFJUN_MA0462.3 7 bp overlap
BNC2 2 datasets
Motif DE_36h DE_36h-BNC2_MA1928.2 7 bp overlap
Motif DE_60h DE_60h-BNC2_MA1928.2 7 bp overlap
BRD4 1 dataset
ChIP MCF-10A ERP003925.BRD4.MCF-10A 245 bp overlap
CTBP2 1 dataset
ChIP MCF-7 GSE107013.CTBP2.MCF-7 126 bp overlap
EOMES 3 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ESR1 21 datasets
ChIP MCF-7 GSE48930.ESR1.MCF-7 204 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 248 bp overlap
ChIP MCF-7_E2 GSE102410.ESR1.MCF-7_E2 308 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 145 bp overlap
ChIP MCF-7_E2+4OHT GSE119702.ESR1.MCF-7_E2+4OHT 165 bp overlap
ChIP MCF-7_E2-80min-ERalpha GSE94023.ESR1.MCF-7_E2-80min-ERalpha 184 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 283 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 139 bp overlap
ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 183 bp overlap
ChIP MCF-7_OHT GSE119702.ESR1.MCF-7_OHT 165 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 189 bp overlap
ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 134 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 313 bp overlap
ChIP MCF-7_Tamoxifen GSE102410.ESR1.MCF-7_Tamoxifen 242 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 249 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 197 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 265 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 240 bp overlap
ChIP SUM44PE_ESR1_wildtype GSE100074.ESR1.SUM44PE_ESR1_wildtype 264 bp overlap
ChIP breast_tumor_Male_26 GSE104399.ESR1.breast_tumor_Male_26 190 bp overlap
ChIP pleural-effusion GSE86538.ESR1.pleural-effusion 143 bp overlap
ESR1_D538G 1 dataset
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 202 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 263 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 155 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 333 bp overlap
FOS 5 datasets
Motif DE_36h DE_36h-FOS_MA0476.2 8 bp overlap
Motif DE_60h DE_60h-FOS_MA0476.2 8 bp overlap
ChIP HeLa-S3 ENCSR000EZE.FOS.HeLa-S3 153 bp overlap
ChIP MCF-7 ENCFF282FWZ 401 bp overlap
ChIP MCF-7 ENCSR569XNP.FOS.MCF-7 288 bp overlap
FOS::JUN 2 datasets
Motif DE_36h DE_36h-FOSJUN_MA0099.4 9 bp overlap
Motif DE_60h DE_60h-FOSJUN_MA0099.4 9 bp overlap
FOS::JUNB 2 datasets
Motif DE_36h DE_36h-FOSJUNB_MA1134.2 9 bp overlap
Motif DE_60h DE_60h-FOSJUNB_MA1134.2 9 bp overlap
FOS::JUND 2 datasets
Motif DE_36h DE_36h-FOSJUND_MA1141.2 9 bp overlap
Motif DE_60h DE_60h-FOSJUND_MA1141.2 9 bp overlap
FOSB::JUNB 2 datasets
Motif DE_36h DE_36h-FOSBJUNB_MA1135.2 9 bp overlap
Motif DE_60h DE_60h-FOSBJUNB_MA1135.2 9 bp overlap
FOSL1 2 datasets
Motif DE_36h DE_36h-FOSL1_MA0477.3 9 bp overlap
Motif DE_60h DE_60h-FOSL1_MA0477.3 9 bp overlap
FOSL1::JUN 2 datasets
Motif DE_36h DE_36h-FOSL1JUN_MA1128.2 9 bp overlap
Motif DE_60h DE_60h-FOSL1JUN_MA1128.2 9 bp overlap
FOSL1::JUNB 2 datasets
Motif DE_36h DE_36h-FOSL1JUNB_MA1137.2 9 bp overlap
Motif DE_60h DE_60h-FOSL1JUNB_MA1137.2 9 bp overlap
FOSL1::JUND 2 datasets
Motif DE_36h DE_36h-FOSL1JUND_MA1142.2 8 bp overlap
Motif DE_60h DE_60h-FOSL1JUND_MA1142.2 8 bp overlap
FOSL2 2 datasets
Motif DE_36h DE_36h-FOSL2_MA0478.2 10 bp overlap
Motif DE_60h DE_60h-FOSL2_MA0478.2 10 bp overlap
FOSL2::JUN 2 datasets
Motif DE_36h DE_36h-FOSL2JUN_MA1130.2 9 bp overlap
Motif DE_60h DE_60h-FOSL2JUN_MA1130.2 9 bp overlap
FOSL2::JUNB 2 datasets
Motif DE_36h DE_36h-FOSL2JUNB_MA1138.2 9 bp overlap
Motif DE_60h DE_60h-FOSL2JUNB_MA1138.2 9 bp overlap
FOSL2::JUND 2 datasets
Motif DE_36h DE_36h-FOSL2JUND_MA1144.2 9 bp overlap
Motif DE_60h DE_60h-FOSL2JUND_MA1144.2 9 bp overlap
FOXA1 5 datasets
ChIP 22Rv1_Dox GSE85558.FOXA1.22Rv1_Dox 214 bp overlap
ChIP LNCaP_F266S_shFOXA1 GSE128883.FOXA1.LNCaP_F266S_shFOXA1 164 bp overlap
ChIP MCF-7_TNF GSE59530.FOXA1.MCF-7_TNF 141 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 245 bp overlap
ChIP prostate_2078_T GSE130408.FOXA1.prostate_2078_T 161 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 200 bp overlap
ChIP DE DE-FOXA2-1 579 bp overlap
ChIP DE DE-FOXA2-2 579 bp overlap
GATA1 1 dataset
ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 191 bp overlap
GATA2 6 datasets
ChIP LNCaP GSE38391.GATA2.LNCaP 240 bp overlap
ChIP LNCaP GSE52725.GATA2.LNCaP 240 bp overlap
ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 248 bp overlap
ChIP LNCaP_FBS GSE69043.GATA2.LNCaP_FBS 182 bp overlap
ChIP dermal-fibroblast GSE51025.GATA2.dermal-fibroblast 169 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 195 bp overlap
GATA3 17 datasets
ChIP MCF-7 ENCFF352QVM 191 bp overlap
ChIP MCF-7 ENCFF437NQS 93 bp overlap
ChIP MCF-7 GSE122847.GATA3.MCF-7 267 bp overlap
ChIP MCF-7 GSE51274.GATA3.MCF-7 317 bp overlap
ChIP MCF-7 ENCSR000EWS.GATA3.MCF-7 306 bp overlap
ChIP MCF-7 GSE133072.GATA3.MCF-7 228 bp overlap
ChIP MCF-7_DMSO GSE29073.GATA3.MCF-7_DMSO 128 bp overlap
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 188 bp overlap
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 264 bp overlap
ChIP MCF-7_E2 GSE60270.GATA3.MCF-7_E2 192 bp overlap
ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 162 bp overlap
ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 217 bp overlap
ChIP SK-N-SH ENCFF040SSB 280 bp overlap
ChIP T-47D GSE51274.GATA3.T-47D 256 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 146 bp overlap
ChIP T47D-A1-2_Dex GSE112491.GATA3.T47D-A1-2_Dex 160 bp overlap
ChIP thymocyte GSE71751.GATA3.thymocyte 170 bp overlap
GATA3_Nter 2 datasets
ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 228 bp overlap
ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 231 bp overlap
GATA4 3 datasets
ChIP BJ1-hTERT GSE92491.GATA4.BJ1-hTERT 265 bp overlap
ChIP DE DE-GATA4-1 569 bp overlap
ChIP DE DE-GATA4-2 579 bp overlap
GATA6 9 datasets
ChIP DE DE-GATA6-1 520 bp overlap
ChIP DE DE-GATA6-2 579 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 579 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 523 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 579 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 579 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 579 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 579 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 371 bp overlap
HOXB13 2 datasets
ChIP prostate_2484_T GSE130408.HOXB13.prostate_2484_T 250 bp overlap
ChIP prostate_P25 GSE130408.HOXB13.prostate_P25 242 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 364 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 370 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 420 bp overlap
ChIP MCF-7_Tamoxifen GSE102410.JUN.MCF-7_Tamoxifen 257 bp overlap
JUN::JUNB 2 datasets
Motif DE_36h DE_36h-JUNJUNB_MA1132.2 8 bp overlap
Motif DE_60h DE_60h-JUNJUNB_MA1132.2 8 bp overlap
JUNB 2 datasets
Motif DE_36h DE_36h-JUNB_MA0490.3 9 bp overlap
Motif DE_60h DE_60h-JUNB_MA0490.3 9 bp overlap
JUND 2 datasets
Motif DE_36h DE_36h-JUND_MA0491.3 9 bp overlap
Motif DE_60h DE_60h-JUND_MA0491.3 9 bp overlap
Jun 2 datasets
Motif DE_36h DE_36h-Jun_MA0489.3 8 bp overlap
Motif DE_60h DE_60h-Jun_MA0489.3 8 bp overlap
KLF4 1 dataset
ChIP PDAC GSE64557.KLF4.PDAC 425 bp overlap
LMO2 1 dataset
ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 188 bp overlap
MAF::NFE2 2 datasets
Motif DE_36h DE_36h-MAFNFE2_MA0501.2 11 bp overlap
Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap
MAFK 2 datasets
Motif DE_36h DE_36h-MAFK_MA0496.4 10 bp overlap
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
MAX 1 dataset
ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 151 bp overlap
MEIS1 2 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MGA 3 datasets
Motif DE_36h DE_36h-MGA_MA0801.1 8 bp overlap
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MYC 1 dataset
ChIP HeLa-S3 ENCSR000EZD.MYC.HeLa-S3 108 bp overlap
NELFE 2 datasets
ChIP HeLa GSE125534.NELFE.HeLa 216 bp overlap
ChIP HeLa GSE125534.NELFE.HeLa 128 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 146 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_36h DE_36h-Nr1h3Rxra_MA0494.2 16 bp overlap
PGR 1 dataset
ChIP breast_tumor_Male_26 GSE104399.PGR.breast_tumor_Male_26 254 bp overlap
RCOR1 1 dataset
ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 201 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 166 bp overlap
SIN3A 2 datasets
ChIP MCF-7 ENCFF521RDC 345 bp overlap
ChIP MCF-7 ENCSR000BUM.SIN3A.MCF-7 175 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 240 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 579 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 579 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 579 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 576 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 579 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 579 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 579 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 579 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 195 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 222 bp overlap
SMARCA4 1 dataset
ChIP A-549_AG15685 GSE132290.SMARCA4.A-549_AG15685 104 bp overlap
SNAI2 1 dataset
ChIP PC-9_1DF GSE131687.SNAI2.PC-9_1DF 364 bp overlap
SOX10 2 datasets
Motif DE_36h DE_36h-SOX10_MA0442.3 6 bp overlap
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 504 bp overlap
SREBF1 3 datasets
Motif DE_36h DE_36h-SREBF1_MA0595.1 10 bp overlap
Motif DE_48h DE_48h-SREBF1_MA0595.1 10 bp overlap
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
SREBF2 3 datasets
Motif DE_36h DE_36h-SREBF2_MA0596.1 10 bp overlap
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
STAT3 14 datasets
ChIP HCC70 GSE152203.STAT3.HCC70 315 bp overlap
ChIP MCF-10A ENCSR000DOQ.STAT3.MCF-10A 203 bp overlap
ChIP MCF-7_jc5834 GSE126004.STAT3.MCF-7_jc5834 241 bp overlap
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 354 bp overlap
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 419 bp overlap
ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 385 bp overlap
ChIP MCF-7_jc5844 GSE126004.STAT3.MCF-7_jc5844 325 bp overlap
ChIP MCF-7_jc5848 GSE126004.STAT3.MCF-7_jc5848 261 bp overlap
ChIP MCF10A-Er-Src_TAM GSE115597.STAT3.MCF10A-Er-Src_TAM 168 bp overlap
ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 236 bp overlap
ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 228 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 551 bp overlap
ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 195 bp overlap
ChIP breast-cancer_3487 GSE126004.STAT3.breast-cancer_3487 179 bp overlap
Spz1 2 datasets
Motif DE_36h DE_36h-Spz1_MA0111.1 11 bp overlap
Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap
TBX20 3 datasets
Motif DE_36h DE_36h-TBX20_MA0689.1 11 bp overlap
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TP53 1 dataset
ChIP H9 GSE39912.TP53.H9 207 bp overlap
Thap11 2 datasets
Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap
Motif DE_60h DE_60h-Thap11_MA1573.2 14 bp overlap
YY1AP1 2 datasets
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 466 bp overlap
ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 317 bp overlap
ZBTB32 1 dataset
Motif DE_36h DE_36h-ZBTB32_MA1580.1 10 bp overlap
ZEB1 1 dataset
ChIP NCI-H1975_resistant GSE106896.ZEB1.NCI-H1975_resistant 204 bp overlap
ZFP42 1 dataset
Motif DE_36h DE_36h-ZFP42_MA1651.2 13 bp overlap
ZNF143 1 dataset
ChIP MCF-7 GSE76454.ZNF143.MCF-7 190 bp overlap
ZNF22 1 dataset
ChIP HEK293 GSE76494.ZNF22.HEK293 240 bp overlap
ZNF317 1 dataset
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
ZNF35 1 dataset
ChIP HEK293 GSE76494.ZNF35.HEK293 139 bp overlap
ZNF362 1 dataset
ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 231 bp overlap
ZNF580 1 dataset
ChIP HEK293 ENCSR668HOP.ZNF580.HEK293 274 bp overlap
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