chr16:54,938,813–54,939,012

chr16 : 54,938,813 – 54,939,012

199 bp 60 TFs 5 linked genes

This 199 bp open chromatin element is linked to 5 target genes and is bound by 60 transcription factors.

Linked Genes

5 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000259725		142 bp	At TSS	Proximity
ENSG00000259711		3.9 kb	Proximal	Proximity
IRX5		7.9 kb	Proximal	Proximity
ENSG00000289307		8.2 kb	Proximal	Proximity
CRNDE		10.0 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

60 transcription factors

ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 184 bp overlap

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 191 bp overlap

ChIP breast_tumor_Male_26 GSE104399.AR.breast_tumor_Male_26 112 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 168 bp overlap

ARID2 2 datasets

ChIP Aska-SS GSE108025.ARID2.Aska-SS 55 bp overlap

ChIP Aska-SS_shSSX GSE108025.ARID2.Aska-SS_shSSX 175 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 199 bp overlap

BRD4 3 datasets

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 162 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 199 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 199 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 195 bp overlap

CBX7 2 datasets

ChIP hESC GSE133412.CBX7.hESC 194 bp overlap

ChIP hESC_TKO GSE133412.CBX7.hESC_TKO 184 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 199 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 199 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 199 bp overlap

CTCF 43 datasets

ChIP A-673 ENCSR611JJS.CTCF.A-673 174 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 199 bp overlap

ChIP WERI-Rb-1 ENCFF349QKF 165 bp overlap

ChIP WERI-Rb-1 ENCSR000DXW.CTCF.WERI-Rb-1 134 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 168 bp overlap

ChIP ascending-aorta ENCSR846JKO.CTCF.ascending-aorta 164 bp overlap

ChIP astrocyte of the spinal cord ENCFF213GKL 199 bp overlap

ChIP astrocyte_spinal_cord ENCSR000DSU.CTCF.astrocyte_spinal_cord 141 bp overlap

ChIP bonchial_epithelial ENCSR000DXI.CTCF.bonchial_epithelial 134 bp overlap

ChIP brain microvascular endothelial cell ENCFF526VHE 171 bp overlap

ChIP breast_epithelium ENCSR661NXJ.CTCF.breast_epithelium 53 bp overlap

ChIP chondrocyte ENCFF134ORZ 181 bp overlap

ChIP choroid-plexus_epithelial ENCSR000DTL.CTCF.choroid-plexus_epithelial 113 bp overlap

ChIP cortical-interneuron_KCl-neg_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-neg 125 bp overlap

ChIP cortical-interneuron_KCl-neg_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-neg_JQ1-pos 131 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-neg 156 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-pos GSE117508.CTCF.cortical-interneuron_KCl-pos_JQ1-pos 151 bp overlap

ChIP endothelial_brain-microvascular ENCSR000DTA.CTCF.endothelial_brain-microvascular 84 bp overlap

ChIP epithelial cell of esophagus ENCFF946GGT 199 bp overlap

ChIP epithelial cell of prostate ENCFF086GTI 199 bp overlap

ChIP epithelial_esophagus ENCSR000DTR.CTCF.epithelial_esophagus 122 bp overlap

ChIP epithelial_mammary ENCSR000DUS.CTCF.epithelial_mammary 112 bp overlap

ChIP heart ENCSR232OFD.CTCF.heart 173 bp overlap

ChIP heart left ventricle ENCFF842XRG 199 bp overlap

ChIP heart_left-ventricle ENCSR791AYW.CTCF.heart_left-ventricle 59 bp overlap

ChIP hepatocyte ENCFF263BLJ 199 bp overlap

ChIP hepatocyte ENCSR252QYR.CTCF.hepatocyte 182 bp overlap

ChIP keratinocyte ENCFF046PBT 163 bp overlap

ChIP keratinocyte ENCFF291YDC 163 bp overlap

ChIP keratinocyte ENCSR000ALJ.CTCF.keratinocyte 93 bp overlap

ChIP keratinocyte ENCSR000DNC.CTCF.keratinocyte 143 bp overlap

ChIP left ventricle myocardium inferior ENCFF161DPW 199 bp overlap

ChIP leukemia_CEBPA-168h GSE142161.CTCF.leukemia_CEBPA-168h 170 bp overlap

ChIP leukemia_CEBPA-96h GSE142161.CTCF.leukemia_CEBPA-96h 138 bp overlap

ChIP neural cell ENCFF335ADI 199 bp overlap

ChIP neural progenitor cell ENCFF420RBO 199 bp overlap

ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 111 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 113 bp overlap

ChIP prostate gland ENCFF655GBO 199 bp overlap

ChIP prostate gland ENCFF979KAF 199 bp overlap

ChIP prostate_epithelial ENCSR196HOM.CTCF.prostate_epithelial 199 bp overlap

ChIP prostate_gland ENCSR720USO.CTCF.prostate_gland 199 bp overlap

ChIP prostate_gland ENCSR829HTO.CTCF.prostate_gland 199 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 199 bp overlap

ESR1 7 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 199 bp overlap

ChIP MCF-7_Veh GSE117941.ESR1.MCF-7_Veh 173 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 161 bp overlap

ChIP breast_tumor_Female_6 GSE104399.ESR1.breast_tumor_Female_6 111 bp overlap

ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 199 bp overlap

ChIP breast_tumor_Male_11 GSE104399.ESR1.breast_tumor_Male_11 162 bp overlap

ChIP breast_tumor_Male_26 GSE104399.ESR1.breast_tumor_Male_26 185 bp overlap

ESR1_pS118 2 datasets

ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 104 bp overlap

ChIP MCF-7_Veh_sc GSE117569.ESR1_pS118.MCF-7_Veh_sc 182 bp overlap

EZH2 15 datasets

ChIP GM23338 ENCFF613YON 199 bp overlap

ChIP GM23338 ENCFF886DXX 133 bp overlap

ChIP H1 ENCFF232NZA 199 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 197 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 199 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 199 bp overlap

ChIP fibroblast_DERMAL ENCSR000ASE.EZH2.fibroblast_DERMAL 137 bp overlap

ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 175 bp overlap

ChIP hESC GSE113817.EZH2.hESC 182 bp overlap

ChIP hepatocyte ENCFF552DZB 166 bp overlap

ChIP hepatocyte ENCFF552DZB 166 bp overlap

ChIP neural cell ENCFF610EPB 56 bp overlap

ChIP neural cell ENCFF610EPB 199 bp overlap

ChIP neural progenitor cell ENCFF018MKA 199 bp overlap

ChIP neural progenitor cell ENCFF472NFV 199 bp overlap

EZH2_phosphoT487 1 dataset

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 177 bp overlap

FOXA1 4 datasets

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 168 bp overlap

ChIP breast-cancer_Veh-2858 GSE128018.FOXA1.breast-cancer_Veh-2858 52 bp overlap

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 192 bp overlap

ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 155 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 199 bp overlap

GATA2 2 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 148 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 94 bp overlap

GATA3 2 datasets

ChIP MCF-7 GSE128445.GATA3.MCF-7 135 bp overlap

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 122 bp overlap

GATA3_Nter 1 dataset

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 152 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 117 bp overlap

ChIP DE DE-GATA4-2 50 bp overlap

GATA6 4 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 199 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 199 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 199 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 199 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 199 bp overlap

HNRNPLL 2 datasets

ChIP HepG2 ENCFF952XAB 74 bp overlap

ChIP HepG2 ENCFF952XAB 199 bp overlap

JARID2 3 datasets

ChIP AMIPS8 GSE48516.JARID2.AMIPS8 146 bp overlap

ChIP MRC-5_IPS25 GSE48516.JARID2.MRC-5_IPS25 199 bp overlap

ChIP UTEIPS4 GSE48516.JARID2.UTEIPS4 199 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 199 bp overlap

ChIP MDA-MB-453_DHT GSE45201.MYC.MDA-MB-453_DHT 182 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 175 bp overlap

NANOG 2 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 199 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 170 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 199 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 199 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 152 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 199 bp overlap

PCGF2 1 dataset

ChIP NT2-D1 GSE101538.PCGF2.NT2-D1 88 bp overlap

ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 97 bp overlap

ChIP breast_tumor_Male_26 GSE104399.PGR.breast_tumor_Male_26 199 bp overlap

POLR2A 2 datasets

ChIP breast epithelium ENCFF955FMX 177 bp overlap

ChIP upper lobe of left lung ENCFF640VPA 103 bp overlap

POU2F1 2 datasets

ChIP T-47D GSE148277.POU2F1.T-47D 178 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 199 bp overlap

POU5F1 4 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 199 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 199 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 199 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 199 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 199 bp overlap

RAD21 5 datasets

ChIP H1 ENCFF967OJF 116 bp overlap

ChIP HCT-116 GSE131606.RAD21.HCT-116 191 bp overlap

ChIP HUVEC-C_hypoxia GSE94872.RAD21.HUVEC-C_hypoxia 112 bp overlap

ChIP neural ENCSR198ZYJ.RAD21.neural 199 bp overlap

ChIP neural cell ENCFF564MOT 199 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 199 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 199 bp overlap

RNF2 2 datasets

ChIP HUES-64 GSE104059.RNF2.HUES-64 77 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 199 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 199 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 199 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 199 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 65 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 126 bp overlap

SMARCA4 2 datasets

ChIP MCF-7 GSE140185.SMARCA4.MCF-7 199 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 93 bp overlap

SMARCC1 1 dataset

ChIP Aska-SS_shSSX GSE108025.SMARCC1.Aska-SS_shSSX 164 bp overlap

SMC1 3 datasets

ChIP DKO GSE131606.SMC1.DKO 189 bp overlap

ChIP HCAEC GSE101921.SMC1.HCAEC 87 bp overlap

ChIP IMR-90_G GSE118494.SMC1.IMR-90_G 173 bp overlap

ChIP neural ENCSR404BPV.SMC3.neural 199 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 199 bp overlap

ChIP WTC11 ENCFF688PEU 199 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 199 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 199 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 199 bp overlap

STAG2 1 dataset

ChIP HCAEC GSE101921.STAG2.HCAEC 88 bp overlap

STAT3 1 dataset

ChIP MDA-MB-453 GSE152203.STAT3.MDA-MB-453 59 bp overlap

SUZ12 8 datasets

ChIP H1 ENCFF881NFR 199 bp overlap

ChIP HEK293T_PCGF1352fl GSE119618.SUZ12.HEK293T_PCGF1352fl 121 bp overlap

ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 199 bp overlap

ChIP HEK293T_PCGF135fl_OHT GSE119618.SUZ12.HEK293T_PCGF135fl_OHT 199 bp overlap

ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 183 bp overlap

ChIP NT2-D1 GSE101538.SUZ12.NT2-D1 199 bp overlap

ChIP NT2/D1 ENCFF574SXS 199 bp overlap

ChIP WA01 ENCSR000EUQ.SUZ12.WA01 174 bp overlap

TAF15 1 dataset

ChIP K-562 ENCSR047LSJ.TAF15.K-562 154 bp overlap

TCF7L2 1 dataset

ChIP MDA-MB-453 GSE45201.TCF7L2.MDA-MB-453 107 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 199 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 199 bp overlap

ZBTB33 1 dataset

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 199 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 199 bp overlap