chr16 : 25,855,688 – 25,856,393
705 bp 77 TFs 1 linked gene
This 705 bp open chromatin element is linked to HS3ST4 and is bound by 77 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
HS3ST4 164.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr16:25,850,688 – 25,861,393
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
77 transcription factors
Source
Cell type
ASH2L 3 datasets
ChIP H1 ENCFF399KAM 642 bp overlap
ChIP H1 ENCFF399KAM 648 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 431 bp overlap
ATF2 2 datasets
ChIP WA01 ENCSR000BQU.ATF2.WA01 468 bp overlap
ChIP WA01 ENCSR000BQU.ATF2.WA01 107 bp overlap
BCL11A 2 datasets
ChIP WA01 ENCSR000BMJ.BCL11A.WA01 191 bp overlap
ChIP WA01 ENCSR000BIP.BCL11A.WA01 129 bp overlap
BCL6 2 datasets
Motif DE_48h DE_48h-BCL6_MA0463.3 13 bp overlap
Motif DE_72h DE_72h-BCL6_MA0463.3 13 bp overlap
BCL6B 2 datasets
Motif DE_48h DE_48h-BCL6B_MA0731.1 17 bp overlap
Motif DE_72h DE_72h-BCL6B_MA0731.1 17 bp overlap
BCOR 2 datasets
ChIP WA01 GSE104690.BCOR.WA01 200 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 219 bp overlap
CHD7 1 dataset
ChIP WA01 ENCSR000AVA.CHD7.WA01 132 bp overlap
CTCF 3 datasets
ChIP H9 ENCFF152GTF 461 bp overlap
ChIP endodermal cell ENCFF471YCZ 116 bp overlap
ChIP endodermal cell ENCFF471YCZ 272 bp overlap
CTNNB1 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 295 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 195 bp overlap
EBF1 2 datasets
Motif DE_48h DE_48h-EBF1_MA0154.5 11 bp overlap
Motif DE_72h DE_72h-EBF1_MA0154.5 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 515 bp overlap
EP300 2 datasets
ChIP H1 ENCFF927IYK 297 bp overlap
ChIP WA01 ENCSR000BKK.EP300.WA01 212 bp overlap
Ebf4 2 datasets
Motif DE_48h DE_48h-Ebf4_MA2122.1 11 bp overlap
Motif DE_72h DE_72h-Ebf4_MA2122.1 11 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-1 429 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 193 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 583 bp overlap
ChIP DE DE-GATA4-2 705 bp overlap
ChIP foregut GSE117136.GATA4.foregut 340 bp overlap
GATA6 10 datasets
ChIP DE DE-GATA6-1 581 bp overlap
ChIP DE DE-GATA6-2 601 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 705 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 625 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 705 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 634 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 668 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 705 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 458 bp overlap
ChIP foregut GSE117136.GATA6.foregut 332 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 338 bp overlap
HDAC2 4 datasets
ChIP H1 ENCFF353UJQ 166 bp overlap
ChIP H1 ENCFF939VKA 237 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 318 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 248 bp overlap
HIC2 2 datasets
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
Motif DE_72h DE_72h-HIC2_MA0738.2 6 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 545 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 589 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 655 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 458 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 527 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 621 bp overlap
KLF4 1 dataset
ChIP WA09 GSE105028.KLF4.WA09 210 bp overlap
LEF1 1 dataset
ChIP hESC GSE64758.LEF1.hESC 334 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 390 bp overlap
NANOG 8 datasets
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 705 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 247 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 206 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 705 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 615 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 532 bp overlap
ChIP hESC GSE18292.NANOG.hESC 148 bp overlap
NEUROG2 1 dataset
ChIP MRC-5_N_05DPT GSE75910.NEUROG2.MRC-5_N_05DPT 237 bp overlap
NFATC3 1 dataset
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NFATC4 1 dataset
Motif DE_72h DE_72h-NFATC4_MA1525.3 9 bp overlap
NIPBL 2 datasets
ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 260 bp overlap
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 201 bp overlap
Nfat5 1 dataset
Motif DE_72h DE_72h-Nfat5_MA0606.3 8 bp overlap
Nfatc1 1 dataset
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
OTX2 1 dataset
ChIP WTC11 ENCFF634NAO 245 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 165 bp overlap
PCGF1 1 dataset
ChIP WA01 GSE104690.PCGF1.WA01 305 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_72h DE_72h-POU2F1SOX2_MA1962.1 17 bp overlap
POU5F1 15 datasets
ChIP BG03 GSE21614.POU5F1.BG03 218 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 561 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP H1 ENCFF698ZAP 205 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 705 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 386 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 705 bp overlap
ChIP WA01 ENCSR000BMU.POU5F1.WA01 305 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 169 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 439 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 429 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 199 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 424 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 705 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 362 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 622 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_72h DE_72h-Pou5f1Sox2_MA0142.1 15 bp overlap
RAD21 2 datasets
ChIP WA09 GSE105028.RAD21.WA09 195 bp overlap
ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 333 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 253 bp overlap
REST 1 dataset
Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap
SMAD2 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 395 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 695 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 705 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 705 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 705 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 670 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 705 bp overlap
SMAD3 1 dataset
ChIP hESC GSE29422.SMAD3.hESC 160 bp overlap
SMARCA4 3 datasets
ChIP WA09 GSE105028.SMARCA4.WA09 445 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 538 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 705 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 604 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 705 bp overlap
SMARCC1 5 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 246 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 589 bp overlap
ChIP ESC S25-ESC-d0-BAF155-exp1 303 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 630 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 654 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 247 bp overlap
SOX10 2 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 522 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 490 bp overlap
SOX2 3 datasets
ChIP hESC GSE69479.SOX2.hESC 210 bp overlap
ChIP hESC GSE18292.SOX2.hESC 115 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 524 bp overlap
SOX4 2 datasets
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SP1 2 datasets
ChIP H1 ENCFF263FUH 321 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 395 bp overlap
SP4 1 dataset
ChIP WA01 ENCSR000BQV.SP4.WA01 168 bp overlap
Sox17 2 datasets
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox5 2 datasets
Motif DE_48h DE_48h-Sox5_MA0087.3 8 bp overlap
Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap
Sox7 2 datasets
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
Stat6 2 datasets
Motif DE_48h DE_48h-Stat6_MA0520.2 10 bp overlap
Motif DE_72h DE_72h-Stat6_MA0520.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 554 bp overlap
TAF1 3 datasets
ChIP H1 ENCFF478SZO 485 bp overlap
ChIP H1 ENCFF478SZO 385 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 162 bp overlap
TAF7 1 dataset
ChIP H1 ENCFF061XZZ 337 bp overlap
TCF12 1 dataset
ChIP WA01 ENCSR000BIT.TCF12.WA01 262 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 441 bp overlap
TEAD1 2 datasets
ChIP WTC11 ENCFF502QUV 405 bp overlap
ChIP WTC11 ENCFF502QUV 311 bp overlap
TEAD4 4 datasets
ChIP ESC S26-ESC-d0-TEAD4-exp1 660 bp overlap
ChIP H1 ENCFF778PAX 165 bp overlap
ChIP WTC11 ENCFF114TZS 341 bp overlap
ChIP hESC GSE99202.TEAD4.hESC 190 bp overlap
TFAP2C 1 dataset
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 404 bp overlap
TP53 1 dataset
ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 374 bp overlap
YY1 2 datasets
ChIP H1 ENCFF524BTL 337 bp overlap
ChIP WA01 ENCSR000BKD.YY1.WA01 223 bp overlap
ZNF114 2 datasets
ChIP GM23338 ENCFF631OSW 357 bp overlap
ChIP GM23338 ENCSR555KFE.ZNF114.GM23338 299 bp overlap
ZNF416 2 datasets
Motif DE_48h DE_48h-ZNF416_MA1979.2 10 bp overlap
Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap
ZNF423 1 dataset
ChIP WTC11 ENCFF574PBR 222 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 251 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 491 bp overlap
ZNF75D 1 dataset
Motif DE_72h DE_72h-ZNF75D_MA1601.2 12 bp overlap
ZSCAN16 2 datasets
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_72h DE_72h-ZSCAN16_MA2100.1 18 bp overlap
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