chr16:11,876,086–11,876,741

chr16 : 11,876,086 – 11,876,741

655 bp 80 TFs 8 linked genes

This 655 bp open chromatin element is linked to 8 target genes and is bound by 80 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RSL1D1-DT		24.8 kb	Distal	Multiome
RSL1D1		24.8 kb	Distal	Multiome
GSPT1		39.6 kb	Distal	Multiome
ZC3H7A		79.1 kb	Distal	Multiome
SNX29		100.4 kb	Distal	Multiome
TXNDC11		133.5 kb	Distal	Multiome
SNN		207.9 kb	Distal	Multiome
LITAF		240.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

80 transcription factors

AGO2 3 datasets

ChIP HepG2 ENCFF252VFI 356 bp overlap

ChIP HepG2 ENCFF252VFI 540 bp overlap

ChIP HepG2 ENCFF252VFI 339 bp overlap

ChIP 22Rv1 GSE96652.AR.22Rv1 205 bp overlap

ChIP LNCaP-95_NT GSE125552.AR.LNCaP-95_NT 232 bp overlap

ChIP VCaP GSE148358.AR.VCaP 197 bp overlap

ChIP VCaP_DHAT_2H GSE28950.AR.VCaP_DHAT_2H 217 bp overlap

ChIP VCaP_Darolutamide GSE148358.AR.VCaP_Darolutamide 134 bp overlap

ChIP VCaP_R1881 GSE32892.AR.VCaP_R1881 173 bp overlap

ChIP VCaP_R1881_1C26 GSE32892.AR.VCaP_R1881_1C26 109 bp overlap

ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 137 bp overlap

ChIP VCaP_shERG GSE110655.AR.VCaP_shERG 223 bp overlap

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

ChIP K562 ENCFF511ZZZ 69 bp overlap

EOMES 2 datasets

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 440 bp overlap

ERF::FOXI1 1 dataset

Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap

ERF::FOXO1 1 dataset

Motif DE_72h DE_72h-ERFFOXO1_MA1936.2 12 bp overlap

ChIP breast-cancer_3487 GSE126004.ESR1.breast-cancer_3487 169 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 381 bp overlap

ETV2::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap

FEZF1 1 dataset

ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 309 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap

FOXA1 7 datasets

ChIP 22Rv1 GSE96652.FOXA1.22Rv1 227 bp overlap

ChIP LNCaP-abl GSE63034.FOXA1.LNCaP-abl 188 bp overlap

ChIP LNCaP_DHT GSE28264.FOXA1.LNCaP_DHT 144 bp overlap

ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 128 bp overlap

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 96 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 286 bp overlap

ChIP prostate-cancer_PDX_189-3 GSE130408.FOXA1.prostate-cancer_PDX_189-3 106 bp overlap

FOXA2 5 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 185 bp overlap

ChIP DE DE-FOXA2-1 655 bp overlap

ChIP DE DE-FOXA2-2 655 bp overlap

ChIP PANC-1_HNF1B-OE GSE119930.FOXA2.PANC-1_HNF1B-OE 63 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 334 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 655 bp overlap

ChIP DE DE-GATA4-2 655 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 440 bp overlap

ChIP foregut GSE117136.GATA4.foregut 543 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 538 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 383 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 655 bp overlap

ChIP DE DE-GATA6-2 655 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 655 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 265 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 548 bp overlap

ChIP foregut GSE117136.GATA6.foregut 522 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 499 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 271 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 406 bp overlap

GLYR1 2 datasets

ChIP HeLa GSE20303.GLYR1.HeLa 179 bp overlap

ChIP HeLa GSE20303.GLYR1.HeLa 325 bp overlap

Gfi1B 1 dataset

Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap

HDAC1 1 dataset

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 213 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 156 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 192 bp overlap

HOXB13 1 dataset

ChIP prostate_P19_T GSE130408.HOXB13.prostate_P19_T 167 bp overlap

HOXC6 1 dataset

ChIP 22Rv1 GSE129951.HOXC6.22Rv1 326 bp overlap

Motif DE_72h DE_72h-IRF5_MA1420.1 14 bp overlap

Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 422 bp overlap

KMT2A 1 dataset

ChIP OCI-AML-3_DMSO GSE129636.KMT2A.OCI-AML-3_DMSO 558 bp overlap

Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap

MEIS2 2 datasets

ChIP K-562 ENCSR851BNE.MEIS2.K-562 276 bp overlap

ChIP K562 ENCFF320GSD 290 bp overlap

ChIP CD34 GSE85488.MYC.CD34 113 bp overlap

Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap

Mecom 1 dataset

Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap

NEUROD1 2 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 276 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 282 bp overlap

Motif DE_72h DE_72h-NFIA_MA0670.2 6 bp overlap

Motif DE_72h DE_72h-NFIC_MA0161.3 7 bp overlap

Motif DE_72h DE_72h-NFIX_MA0671.2 6 bp overlap

Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap

Motif DE_72h DE_72h-PAX3_MA1546.2 14 bp overlap

Motif DE_72h DE_72h-PAX6_MA0069.1 14 bp overlap

POLR2A 3 datasets

ChIP HepG2 ENCFF252NAR 78 bp overlap

ChIP HepG2 ENCFF252NAR 467 bp overlap

ChIP spleen ENCFF706IUS 526 bp overlap

POLR2G 2 datasets

ChIP HepG2 ENCFF241AEG 591 bp overlap

ChIP HepG2 ENCFF241AEG 439 bp overlap

POU2F1 2 datasets

ChIP 22Rv1_DHT GSE123565.POU2F1.22Rv1_DHT 223 bp overlap

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 252 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 213 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 296 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

RBM22 2 datasets

ChIP HepG2 ENCFF292RVQ 465 bp overlap

ChIP HepG2 ENCFF561IAJ 157 bp overlap

SALL2 1 dataset

ChIP HEK293 GSE145940.SALL2.HEK293 201 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 583 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 489 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 432 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 156 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 453 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 588 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

STAT3 1 dataset

ChIP breast-cancer_3487 GSE126004.STAT3.breast-cancer_3487 279 bp overlap

Stat2 1 dataset

Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap

Stat4 1 dataset

Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap

Stat5a 1 dataset

Motif DE_72h DE_72h-Stat5a_MA1624.2 9 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 325 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 336 bp overlap

TRPS1 1 dataset

ChIP MCF-7 GSE133072.TRPS1.MCF-7 265 bp overlap

Motif DE_72h DE_72h-Vdr_MA0693.4 7 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 317 bp overlap

ZBTB6 2 datasets

ChIP HEK293 ENCFF881ECZ 313 bp overlap

ChIP HEK293 ENCSR619OUC.ZBTB6.HEK293 206 bp overlap

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 147 bp overlap

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap

Motif DE_72h DE_72h-ZIC5_MA1584.2 15 bp overlap

ZNF135 1 dataset

Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap

ZNF213 1 dataset

Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap

ZNF317 1 dataset

ChIP HEK293 GSE76494.ZNF317.HEK293 207 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 226 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF460 1 dataset

Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap

ZNF680 1 dataset

Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap

ZNF770 1 dataset

Motif DE_72h DE_72h-ZNF770_MA2099.1 8 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap

Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap