chr1 : 225,942,617 – 225,942,892
275 bp 67 TFs 2 linked genes
This 275 bp open chromatin element is linked to LEFTY2 and ENSG00000248322 and is bound by 67 transcription factors.
Linked Genes
2 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LEFTY2 1.4 kb Proximal Proximity
ENSG00000248322 5.1 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr1:225,937,617 – 225,947,892
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
67 transcription factors
Source
Cell type
ARID2 1 dataset
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.ARID2.BIN-67_lentivirus-SMARCA4-K785R 232 bp overlap
ATF1 1 dataset
ChIP WTC11 ENCFF354DFT 250 bp overlap
BACH2 2 datasets
ChIP OCI-Ly7 GSE44420.BACH2.OCI-Ly7 275 bp overlap
ChIP OCI-Ly7 GSE69558.BACH2.OCI-Ly7 263 bp overlap
BCL6 2 datasets
ChIP OCI-Ly7 GSE44420.BCL6.OCI-Ly7 261 bp overlap
ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 175 bp overlap
BHLHE22 1 dataset
ChIP CAL-1 GSE43876.BHLHE22.CAL-1 176 bp overlap
BHLHE40 6 datasets
ChIP GM12878 ENCFF010ZUU 275 bp overlap
ChIP GM12878 ENCFF521IZR 269 bp overlap
ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 275 bp overlap
ChIP GM12878 ENCSR517QHU.BHLHE40.GM12878 235 bp overlap
ChIP GM12878 ENCSR000DZJ.BHLHE40.GM12878 160 bp overlap
ChIP Hep-G2 ENCSR000EDT.BHLHE40.Hep-G2 127 bp overlap
BRD3 1 dataset
ChIP MM1-S GSE43743.BRD3.MM1-S 265 bp overlap
BRD4 7 datasets
ChIP MM1-S GSE45984.BRD4.MM1-S 275 bp overlap
ChIP MM1-S_DMSO GSE42161.BRD4.MM1-S_DMSO 260 bp overlap
ChIP MM1-S_JQ1_150NM GSE49224.BRD4.MM1-S_JQ1_150NM 275 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 275 bp overlap
ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 275 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 275 bp overlap
ChIP MM1-S_JQ1_5UM GSE42355.BRD4.MM1-S_JQ1_5UM 275 bp overlap
CDK8 1 dataset
ChIP MM1-S GSE43743.CDK8.MM1-S 275 bp overlap
CDK9 4 datasets
ChIP MM1-S_DMSO GSE42161.CDK9.MM1-S_DMSO 275 bp overlap
ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 257 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 275 bp overlap
ChIP MM1-S_JQ1_50NM GSE49224.CDK9.MM1-S_JQ1_50NM 275 bp overlap
CTCF 2 datasets
ChIP GSC23 GSE139416.CTCF.GSC23 183 bp overlap
ChIP MM1-S GSE43743.CTCF.MM1-S 193 bp overlap
DPF2 1 dataset
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.DPF2.BIN-67_lentivirus-SMARCA4-K785R 242 bp overlap
EBF1 1 dataset
ChIP GM12878 ENCFF813OXE 134 bp overlap
EED 1 dataset
ChIP GM12878 ENCFF266FYW 254 bp overlap
ERG 4 datasets
ChIP HUVEC-C GSE128382.ERG.HUVEC-C 177 bp overlap
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 171 bp overlap
ChIP aortic-endothelial-cell_D39 GSE139377.ERG.aortic-endothelial-cell_D39 216 bp overlap
ChIP aortic-endothelial-cell_D46 GSE139377.ERG.aortic-endothelial-cell_D46 218 bp overlap
ESR1 10 datasets
ChIP Ishikawa ENCSR000BIY.ESR1.Ishikawa 178 bp overlap
ChIP Ishikawa_C2-14 GSE147141.ESR1.Ishikawa_C2-14 275 bp overlap
ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 275 bp overlap
ChIP Ishikawa_E2_D538G GSE132426.ESR1.Ishikawa_E2_D538G 181 bp overlap
ChIP Ishikawa_E2_D538G_clone2 GSE132426.ESR1.Ishikawa_E2_D538G_clone2 275 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 168 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 127 bp overlap
ChIP U2OS_10nM-E2 GSE151039.ESR1.U2OS_10nM-E2 275 bp overlap
ChIP U2OS_10nM-E2-B GSE151039.ESR1.U2OS_10nM-E2-B 265 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 265 bp overlap
ETS1 2 datasets
ChIP HUVEC-C GSE41166.ETS1.HUVEC-C 132 bp overlap
ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 267 bp overlap
EZH2 1 dataset
ChIP WSU-DLCL2 GSE45982.EZH2.WSU-DLCL2 56 bp overlap
FLI1 1 dataset
ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 234 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 253 bp overlap
ChIP DE DE-GATA4-2 250 bp overlap
GATA6 2 datasets
ChIP DE DE-GATA6-1 266 bp overlap
ChIP DE DE-GATA6-2 224 bp overlap
IKZF1 1 dataset
ChIP GM12878 ENCFF753XDO 275 bp overlap
IKZF2 4 datasets
ChIP GM12878 ENCFF238LYK 275 bp overlap
ChIP GM12878 ENCFF918AID 275 bp overlap
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 233 bp overlap
ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 229 bp overlap
IRF4 3 datasets
ChIP NCI-H929 GSE142493.IRF4.NCI-H929 185 bp overlap
ChIP NCI-H929 GSE56857.IRF4.NCI-H929 185 bp overlap
ChIP U266 GSE142493.IRF4.U266 239 bp overlap
MAFK 1 dataset
ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 275 bp overlap
MAX 1 dataset
ChIP Ishikawa ENCSR000BTY.MAX.Ishikawa 140 bp overlap
MED1 7 datasets
ChIP MM1-S_BIORU GSE45984.MED1.MM1-S_BIORU 275 bp overlap
ChIP MM1-S_JQ1 GSE42161.MED1.MM1-S_JQ1 275 bp overlap
ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 275 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 275 bp overlap
ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 275 bp overlap
ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 275 bp overlap
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 151 bp overlap
MEF2B 1 dataset
ChIP OCI-Ly7 GSE69558.MEF2B.OCI-Ly7 167 bp overlap
MYC 1 dataset
ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 275 bp overlap
NANOG 4 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 266 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 265 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 268 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 275 bp overlap
NR2F1 2 datasets
ChIP GM12878 ENCFF273VKX 189 bp overlap
ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 275 bp overlap
NR2F2 3 datasets
ChIP liver ENCFF565JGD 275 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 237 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 202 bp overlap
PAX5 1 dataset
ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 129 bp overlap
PKNOX1 2 datasets
ChIP GM12878 ENCFF589FCY 258 bp overlap
ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 275 bp overlap
POLR2A 2 datasets
ChIP spleen ENCFF446ZGT 160 bp overlap
ChIP transverse colon ENCFF610RWV 275 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 275 bp overlap
RAD21 1 dataset
ChIP lymphoblast GSE155324.RAD21.lymphoblast 162 bp overlap
RBPJ 2 datasets
ChIP HCC1599 GSE116871.RBPJ.HCC1599 202 bp overlap
ChIP HCC1599_GSI GSE116871.RBPJ.HCC1599_GSI 183 bp overlap
RELA 5 datasets
ChIP HUVEC-C_TNF-30min GSE121890.RELA.HUVEC-C_TNF-30min 135 bp overlap
ChIP HUVEC-C_TNF_30M GSE34500.RELA.HUVEC-C_TNF_30M 135 bp overlap
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 232 bp overlap
ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 186 bp overlap
ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 207 bp overlap
RUNX3 1 dataset
ChIP GM12878 ENCFF395WHA 275 bp overlap
SMAD2 4 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 228 bp overlap
ChIP hESC GSE29422.SMAD2.hESC 224 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 275 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 275 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 275 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 275 bp overlap
SMAD2_3 6 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 275 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 275 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 275 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 275 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 275 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 275 bp overlap
SMAD3 1 dataset
ChIP hESC GSE29422.SMAD3.hESC 235 bp overlap
SMAD4 2 datasets
ChIP endoderm GSE29422.SMAD4.endoderm 204 bp overlap
ChIP hESC GSE29422.SMAD4.hESC 194 bp overlap
SMARCA4 2 datasets
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 275 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 239 bp overlap
SMARCC1 1 dataset
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-K785R 213 bp overlap
SOX11 1 dataset
ChIP GRANT-A519 GSE52146.SOX11.GRANT-A519 90 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 221 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 275 bp overlap
SOX2 1 dataset
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 184 bp overlap
SP1 1 dataset
ChIP GM12878 ENCSR000BHK.SP1.GM12878 119 bp overlap
SPI1 5 datasets
ChIP GM12878 ENCFF134LCP 192 bp overlap
ChIP GM12891 ENCFF563IUT 156 bp overlap
ChIP GM12891 ENCSR000BIJ.SPI1.GM12891 161 bp overlap
ChIP NCI-H929 GSE56857.SPI1.NCI-H929 217 bp overlap
ChIP OCI-Ly7 GSE69558.SPI1.OCI-Ly7 199 bp overlap
SPIB 1 dataset
ChIP OCI-Ly3 GSE56857.SPIB.OCI-Ly3 164 bp overlap
TARDBP 1 dataset
ChIP K-562 ENCSR353HEP.TARDBP.K-562 109 bp overlap
TBX21 2 datasets
ChIP GM12878 ENCFF951HUW 275 bp overlap
ChIP GM12878 ENCSR739IHN.TBX21.GM12878 254 bp overlap
TCF12 2 datasets
ChIP GM12878 ENCFF506WWB 203 bp overlap
ChIP GM12878 ENCSR000BGZ.TCF12.GM12878 169 bp overlap
TCF3 3 datasets
ChIP GM12878 ENCFF658WIO 219 bp overlap
ChIP GM12878 ENCSR000BQT.TCF3.GM12878 221 bp overlap
ChIP Ramos GSE139810.TCF3.Ramos 214 bp overlap
TCF4 2 datasets
ChIP CAL-1 GSE76147.TCF4.CAL-1 222 bp overlap
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 209 bp overlap
TERF1 1 dataset
ChIP LCL GSE55053.TERF1.LCL 217 bp overlap
TERF2 1 dataset
ChIP LCL GSE55053.TERF2.LCL 189 bp overlap
TFAP2C 2 datasets
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 230 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 174 bp overlap
ZBTB7A 1 dataset
ChIP Ishikawa ENCFF191NFH 53 bp overlap
ZEB1 1 dataset
ChIP GM12878 ENCSR000BND.ZEB1.GM12878 187 bp overlap
ZFX 1 dataset
ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 186 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 154 bp overlap
ZNF3 1 dataset
ChIP K-562 ENCSR195QFV.ZNF3.K-562 80 bp overlap
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