chr12 : 74,541,189 – 74,541,399

210 bp 71 TFs 2 linked genes

This 210 bp open chromatin element is linked to ENSG00000257386 and ATXN7L3B and is bound by 71 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000257386		2.6 kb	Proximal	Proximity
ATXN7L3B		3.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

71 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 68 bp overlap

BCL11A 3 datasets

ChIP H1 ENCFF836SSR 177 bp overlap

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 169 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 117 bp overlap

BRD4 1 dataset

ChIP hESC GSE33281.BRD4.hESC 66 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

E2F6 2 datasets

Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 116 bp overlap

ELF1 1 dataset

Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap

EP300 2 datasets

ChIP H1 ENCFF927IYK 210 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 154 bp overlap

ESR1 1 dataset

ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 162 bp overlap

FOXD3 1 dataset

Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap

GATA1 1 dataset

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 161 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000BNR.HDAC2.WA01 119 bp overlap

HIC1 1 dataset

ChIP HEK293 ENCSR803GYT.HIC1.HEK293 87 bp overlap

HIC2 1 dataset

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HLF 1 dataset

Motif DE_12h DE_12h-HLF_MA0043.4 9 bp overlap

HNRNPK 1 dataset

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 210 bp overlap

HOXB13 1 dataset

Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap

Hmga1 1 dataset

Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap

IRF7 1 dataset

Motif DE_12h DE_12h-IRF7_MA0772.2 13 bp overlap

Ikzf3 1 dataset

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 109 bp overlap

KLF16 1 dataset

Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap

MAX 1 dataset

ChIP H1 ENCFF914VQY 210 bp overlap

MEF2A 1 dataset

Motif DE_12h DE_12h-MEF2A_MA0052.5 10 bp overlap

MEF2C 1 dataset

Motif DE_12h DE_12h-MEF2C_MA0497.2 11 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 120 bp overlap

NANOG 6 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 210 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 210 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 157 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 210 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 187 bp overlap

ChIP hESC GSE18292.NANOG.hESC 78 bp overlap

NFIL3 1 dataset

Motif DE_12h DE_12h-NFIL3_MA0025.3 9 bp overlap

NRF1 1 dataset

ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 131 bp overlap

Nrf1 1 dataset

Motif DE_12h DE_12h-Nrf1_MA0506.3 12 bp overlap

PAF1 1 dataset

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 210 bp overlap

POLR2A 1 dataset

ChIP HepG2 ENCFF350RIU 210 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 9 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP GM23338 ENCFF333SNB 210 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 210 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 210 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 164 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 128 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 210 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 210 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 123 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

RBFOX2 3 datasets

ChIP HepG2 ENCFF939HTZ 210 bp overlap

ChIP HepG2 ENCFF939HTZ 181 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 128 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

RELB 1 dataset

ChIP GM12878 ENCSR387QUV.RELB.GM12878 51 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

RUNX1 2 datasets

ChIP 697 GSE138031.RUNX1.697 124 bp overlap

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 142 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 125 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 210 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 210 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 184 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 170 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 210 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 208 bp overlap

SOX10 1 dataset

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

SOX2 1 dataset

ChIP hiPSC GSE56567.SOX2.hiPSC 201 bp overlap

SOX4 1 dataset

Motif DE_12h DE_12h-SOX4_MA0867.3 8 bp overlap

SP1 3 datasets

ChIP H1 ENCFF263FUH 210 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 210 bp overlap

ChIP WTC11 ENCFF688PEU 210 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SUPT5H 1 dataset

ChIP K562 ENCFF902PAW 210 bp overlap

Sox11 1 dataset

Motif DE_12h DE_12h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_12h DE_12h-Sox17_MA0078.3 10 bp overlap

Sox5 1 dataset

Motif DE_12h DE_12h-Sox5_MA0087.3 8 bp overlap

Sox6 1 dataset

Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_12h DE_12h-Sox7_MA2095.1 10 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 188 bp overlap

Wt1 1 dataset

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

YY1 2 datasets

ChIP H1 ENCFF524BTL 210 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 185 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF281 1 dataset

Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 152 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 132 bp overlap

ZNF558 1 dataset

Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap