chr9:111,603,576–111,604,637

chr9 : 111,603,576 – 111,604,637

1,061 bp 88 TFs 6 linked genes

This 1.1 kb open chromatin element is linked to 6 target genes and is bound by 88 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PTGR1		4.2 kb	Proximal	Proximity
DNAJC25		27.2 kb	Distal	Multiome
GNG10		57.4 kb	Distal	Multiome+HiCAR
ZNF483		78.9 kb	Distal	Multiome
ECPAS		119.8 kb	Distal	Multiome
UGCG		292.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

Arid5a 1 dataset

Motif DE_72h DE_72h-Arid5a_MA0602.2 8 bp overlap

BARX1 2 datasets

Motif DE_60h DE_60h-BARX1_MA0875.2 6 bp overlap

Motif DE_72h DE_72h-BARX1_MA0875.2 6 bp overlap

BRD4 2 datasets

ChIP COLO-205 GSE73319.BRD4.COLO-205 234 bp overlap

ChIP HT29 GSE73319.BRD4.HT29 240 bp overlap

Motif DE_60h DE_60h-BSX_MA0876.2 6 bp overlap

Motif DE_72h DE_72h-BSX_MA0876.2 6 bp overlap

ChIP K-562 ENCSR000ATU.CBX2.K-562 263 bp overlap

CBX8 2 datasets

ChIP K-562 ENCSR000ATW.CBX8.K-562 242 bp overlap

ChIP K-562 ENCSR000ATW.CBX8.K-562 244 bp overlap

ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 120 bp overlap

CEBPG 2 datasets

Motif DE_48h DE_48h-CEBPG_MA0838.1 10 bp overlap

Motif DE_72h DE_72h-CEBPG_MA0838.1 10 bp overlap

DLX1 2 datasets

Motif DE_60h DE_60h-DLX1_MA0879.3 6 bp overlap

Motif DE_72h DE_72h-DLX1_MA0879.3 6 bp overlap

DLX6 2 datasets

Motif DE_60h DE_60h-DLX6_MA0882.2 6 bp overlap

Motif DE_72h DE_72h-DLX6_MA0882.2 6 bp overlap

Dlx3 2 datasets

Motif DE_60h DE_60h-Dlx3_MA0880.2 6 bp overlap

Motif DE_72h DE_72h-Dlx3_MA0880.2 6 bp overlap

Dlx4 2 datasets

Motif DE_60h DE_60h-Dlx4_MA0881.2 6 bp overlap

Motif DE_72h DE_72h-Dlx4_MA0881.2 6 bp overlap

EOMES 1 dataset

Motif DE_72h DE_72h-EOMES_MA0800.2 9 bp overlap

ESR1 5 datasets

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 193 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 193 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 180 bp overlap

ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 200 bp overlap

ChIP primary-endometrium-cancer_E1_DSG GSE114737.ESR1.primary-endometrium-cancer_E1_DSG 440 bp overlap

ChIP ProEs_SHCTR GSE59087.EZH2.ProEs_SHCTR 175 bp overlap

FOSL2 1 dataset

ChIP MCF-7 ENCFF188KBZ 581 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 846 bp overlap

ChIP DE DE-FOXA2-2 820 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 884 bp overlap

ChIP DE DE-GATA4-2 883 bp overlap

ChIP foregut GSE117136.GATA4.foregut 261 bp overlap

ChIP foregut GSE117136.GATA4.foregut 277 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 857 bp overlap

ChIP DE DE-GATA6-2 975 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 834 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 722 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 802 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 685 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 737 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 851 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 151 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 699 bp overlap

ChIP foregut GSE117136.GATA6.foregut 262 bp overlap

GBX2 2 datasets

Motif DE_60h DE_60h-GBX2_MA0890.2 6 bp overlap

Motif DE_72h DE_72h-GBX2_MA0890.2 6 bp overlap

ChIP HepG2 ENCFF472INF 557 bp overlap

HESX1 2 datasets

Motif DE_60h DE_60h-HESX1_MA0894.2 6 bp overlap

Motif DE_72h DE_72h-HESX1_MA0894.2 6 bp overlap

HNF4A 1 dataset

ChIP liver ENCFF354NRH 405 bp overlap

HOXA7 2 datasets

Motif DE_60h DE_60h-HOXA7_MA1498.3 6 bp overlap

Motif DE_72h DE_72h-HOXA7_MA1498.3 6 bp overlap

Hnf1A 2 datasets

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

Hoxa13 1 dataset

Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 456 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 407 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 813 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 951 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 834 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 274 bp overlap

LBX2 2 datasets

Motif DE_60h DE_60h-LBX2_MA0699.2 6 bp overlap

Motif DE_72h DE_72h-LBX2_MA0699.2 6 bp overlap

LHX2 2 datasets

Motif DE_60h DE_60h-LHX2_MA0700.3 6 bp overlap

Motif DE_72h DE_72h-LHX2_MA0700.3 6 bp overlap

MAFG::NFE2L1 2 datasets

Motif DE_48h DE_48h-MAFGNFE2L1_MA0089.3 11 bp overlap

Motif DE_72h DE_72h-MAFGNFE2L1_MA0089.3 11 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 231 bp overlap

MEIS1 2 datasets

Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

Motif DE_72h DE_72h-MGA_MA0801.1 8 bp overlap

MGA::EVX1 1 dataset

Motif DE_72h DE_72h-MGAEVX1_MA1960.2 11 bp overlap

MSX1 2 datasets

Motif DE_60h DE_60h-MSX1_MA0666.3 6 bp overlap

Motif DE_72h DE_72h-MSX1_MA0666.3 6 bp overlap

MSX2 2 datasets

Motif DE_60h DE_60h-MSX2_MA0708.3 6 bp overlap

Motif DE_72h DE_72h-MSX2_MA0708.3 6 bp overlap

Msx3 2 datasets

Motif DE_60h DE_60h-Msx3_MA0709.2 6 bp overlap

Motif DE_72h DE_72h-Msx3_MA0709.2 6 bp overlap

Nobox 2 datasets

Motif DE_60h DE_60h-Nobox_MA0125.2 6 bp overlap

Motif DE_72h DE_72h-Nobox_MA0125.2 6 bp overlap

ONECUT1 1 dataset

Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 58 bp overlap

POU1F1 1 dataset

Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif DE_60h DE_60h-RAX_MA0718.2 6 bp overlap

Motif DE_72h DE_72h-RAX_MA0718.2 6 bp overlap

Motif DE_72h DE_72h-RELA_MA0107.1 10 bp overlap

Motif DE_72h DE_72h-RELB_MA1117.2 7 bp overlap

ChIP K-562 ENCSR820GND.RNF2.K-562 224 bp overlap

SATB1 1 dataset

Motif DE_48h DE_48h-SATB1_MA1963.2 7 bp overlap

SMAD2 4 datasets

Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 139 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 1022 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 896 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 939 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 939 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 845 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 771 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 895 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 1005 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 839 bp overlap

SOX14 2 datasets

Motif DE_60h DE_60h-SOX14_MA1562.2 9 bp overlap

Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap

SOX15 2 datasets

Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap

Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 516 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 645 bp overlap

SOX18 2 datasets

Motif DE_60h DE_60h-SOX18_MA1563.2 8 bp overlap

Motif DE_72h DE_72h-SOX18_MA1563.2 8 bp overlap

SOX2 2 datasets

ChIP LK2_DNp63 GSE137459.SOX2.LK2_DNp63 476 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 474 bp overlap

ChIP HepG2 ENCFF470KZD 405 bp overlap

SOX8 2 datasets

Motif DE_60h DE_60h-SOX8_MA0868.3 7 bp overlap

Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap

SOX9 2 datasets

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

Motif DE_72h DE_72h-SOX9_MA0077.2 8 bp overlap

Sox17 2 datasets

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox5 2 datasets

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

Sox7 2 datasets

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 228 bp overlap

Motif DE_72h DE_72h-TBR1_MA0802.2 9 bp overlap

Motif DE_72h DE_72h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_72h DE_72h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_72h DE_72h-TBX18_MA1565.2 9 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_72h DE_72h-TBX20_MA0689.1 11 bp overlap

TBX21 1 dataset

Motif DE_72h DE_72h-TBX21_MA0690.3 10 bp overlap

Motif DE_72h DE_72h-TBX3_MA1566.3 9 bp overlap

Motif DE_72h DE_72h-TBX5_MA0807.1 8 bp overlap

TCF7L1 2 datasets

Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap

Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 2 datasets

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TEAD4 1 dataset

ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 159 bp overlap

TERF2 1 dataset

ChIP HEK293_HHV6-GFP GSE121985.TERF2.HEK293_HHV6-GFP 206 bp overlap

Motif DE_72h DE_72h-Tbx6_MA1567.3 9 bp overlap

ZBED4 1 dataset

ChIP Hep-G2 ENCSR409PMR.ZBED4.Hep-G2 202 bp overlap

ZFP36 2 datasets

ChIP K-562 ENCSR776CYN.ZFP36.K-562 141 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 109 bp overlap

ZGPAT 1 dataset

ChIP Hep-G2 ENCSR704IGU.ZGPAT.Hep-G2 220 bp overlap

ZNF547 1 dataset

ChIP HepG2 ENCFF834XWI 651 bp overlap

ZNF701 2 datasets

Motif DE_60h DE_60h-ZNF701_MA1987.2 17 bp overlap

Motif DE_72h DE_72h-ZNF701_MA1987.2 17 bp overlap

Zic1::Zic2 3 datasets

Motif DE_48h DE_48h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_60h DE_60h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_72h DE_72h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 3 datasets

Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap

Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap

Motif DE_72h DE_72h-Zic2_MA1629.2 9 bp overlap

Zic3 3 datasets

Motif DE_48h DE_48h-Zic3_MA0697.3 7 bp overlap

Motif DE_60h DE_60h-Zic3_MA0697.3 7 bp overlap

Motif DE_72h DE_72h-Zic3_MA0697.3 7 bp overlap