chr8 : 57,993,081 – 57,993,302

221 bp 90 TFs 1 linked gene

This 221 bp open chromatin element is linked to FAM110B and is bound by 90 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
FAM110B		1.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

Ahr::Arnt 1 dataset

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

Alx4 1 dataset

Motif DE_12h DE_12h-Alx4_MA0853.2 12 bp overlap

Arx 1 dataset

Motif DE_12h DE_12h-Arx_MA0874.2 10 bp overlap

Ascl2 1 dataset

Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap

BARX1 1 dataset

Motif DE_12h DE_12h-BARX1_MA0875.2 6 bp overlap

BHLHE22 1 dataset

Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap

BRD4 1 dataset

ChIP 22Rv1_DHT-DMSO GSE118247.BRD4.22Rv1_DHT-DMSO 159 bp overlap

BSX 1 dataset

Motif DE_12h DE_12h-BSX_MA0876.2 6 bp overlap

CDK6 1 dataset

ChIP KB_IL GSE52469.CDK6.KB_IL 108 bp overlap

CREB1 4 datasets

ChIP Hep-G2 ENCSR112ALD.CREB1.Hep-G2 111 bp overlap

ChIP MCF-7 ENCSR620DUQ.CREB1.MCF-7 221 bp overlap

ChIP MCF-7 ENCSR897JAS.CREB1.MCF-7 196 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 148 bp overlap

DLX1 1 dataset

Motif DE_12h DE_12h-DLX1_MA0879.3 6 bp overlap

DLX6 1 dataset

Motif DE_12h DE_12h-DLX6_MA0882.2 6 bp overlap

DPF2 1 dataset

ChIP MCF-7 ENCSR234VCE.DPF2.MCF-7 221 bp overlap

Dlx2 1 dataset

Motif DE_12h DE_12h-Dlx2_MA0885.3 8 bp overlap

Dlx3 1 dataset

Motif DE_12h DE_12h-Dlx3_MA0880.2 6 bp overlap

Dlx4 1 dataset

Motif DE_12h DE_12h-Dlx4_MA0881.2 6 bp overlap

Dlx5 1 dataset

Motif DE_12h DE_12h-Dlx5_MA1476.3 8 bp overlap

EN2 1 dataset

Motif DE_12h DE_12h-EN2_MA0642.3 7 bp overlap

ERF::NHLH1 1 dataset

Motif ES_0h ES_0h-ERFNHLH1_MA1938.2 16 bp overlap

ETV1 2 datasets

Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap

Motif ES_0h ES_0h-ETV1_MA0761.3 9 bp overlap

FOXA1 1 dataset

ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 221 bp overlap

GBX1 1 dataset

Motif DE_12h DE_12h-GBX1_MA0889.2 7 bp overlap

GBX2 1 dataset

Motif DE_12h DE_12h-GBX2_MA0890.2 6 bp overlap

HESX1 1 dataset

Motif DE_12h DE_12h-HESX1_MA0894.2 6 bp overlap

HNRNPK 1 dataset

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 156 bp overlap

HOXA7 1 dataset

Motif DE_12h DE_12h-HOXA7_MA1498.3 6 bp overlap

IKZF2 2 datasets

Motif DE_12h DE_12h-IKZF2_MA2326.1 6 bp overlap

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

IKZF3 2 datasets

ChIP HEK293 ENCFF518OXG 221 bp overlap

ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 155 bp overlap

Ikzf3 2 datasets

Motif DE_12h DE_12h-Ikzf3_MA1992.2 9 bp overlap

Motif ES_0h ES_0h-Ikzf3_MA1992.2 9 bp overlap

KLF14 1 dataset

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

KLF5 1 dataset

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

KLF9 3 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 71 bp overlap

LBX1 1 dataset

Motif DE_12h DE_12h-LBX1_MA0618.2 7 bp overlap

LBX2 1 dataset

Motif DE_12h DE_12h-LBX2_MA0699.2 6 bp overlap

LHX2 1 dataset

Motif DE_12h DE_12h-LHX2_MA0700.3 6 bp overlap

LHX9 1 dataset

Motif DE_12h DE_12h-LHX9_MA0701.3 7 bp overlap

Lhx1 1 dataset

Motif DE_12h DE_12h-Lhx1_MA1518.3 10 bp overlap

MAZ 2 datasets

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

ChIP HEK293 GSE76494.MAZ.HEK293 137 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MGA 2 datasets

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

Motif ES_0h ES_0h-MGA_MA0801.1 8 bp overlap

MSX1 1 dataset

Motif DE_12h DE_12h-MSX1_MA0666.3 6 bp overlap

MSX2 1 dataset

Motif DE_12h DE_12h-MSX2_MA0708.3 6 bp overlap

MYOG 1 dataset

Motif ES_0h ES_0h-MYOG_MA0500.3 8 bp overlap

Msx3 1 dataset

Motif DE_12h DE_12h-Msx3_MA0709.2 6 bp overlap

NFYB 2 datasets

ChIP Hep-G2 ENCSR935GZV.NFYB.Hep-G2 210 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 164 bp overlap

NFYC 1 dataset

ChIP Hep-G2 ENCSR569ARC.NFYC.Hep-G2 170 bp overlap

Neurod2 1 dataset

Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap

Nobox 1 dataset

Motif DE_12h DE_12h-Nobox_MA0125.2 6 bp overlap

Olig2 1 dataset

Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap

PBX1 2 datasets

ChIP A-549 ENCSR637RKG.PBX1.A-549 170 bp overlap

ChIP A549 ENCFF475JCE 209 bp overlap

PBX2 3 datasets

ChIP HepG2 ENCFF225AJT 221 bp overlap

ChIP K-562 ENCSR263DFP.PBX2.K-562 217 bp overlap

ChIP K562 ENCFF286KMN 221 bp overlap

PBX3 2 datasets

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 138 bp overlap

ChIP SK-N-SH ENCFF876BMC 170 bp overlap

PKNOX1 8 datasets

ChIP GM12878 ENCFF589FCY 129 bp overlap

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 221 bp overlap

ChIP HEK293T ENCFF174WDB 221 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 221 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 221 bp overlap

ChIP K562 ENCFF236IUS 221 bp overlap

ChIP MCF-7 ENCFF116OCS 221 bp overlap

ChIP MCF-7 ENCSR986XYK.PKNOX1.MCF-7 221 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 3 datasets

ChIP 22Rv1_DHT GSE123565.POU2F1.22Rv1_DHT 221 bp overlap

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 221 bp overlap

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 120 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 1 dataset

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 221 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PRDM10 1 dataset

ChIP HEK293 ENCFF145WQQ 201 bp overlap

PRRX2 1 dataset

Motif DE_12h DE_12h-PRRX2_MA0075.4 7 bp overlap

RAX 1 dataset

Motif DE_12h DE_12h-RAX_MA0718.2 6 bp overlap

REL 1 dataset

Motif DE_12h DE_12h-REL_MA0101.1 10 bp overlap

RELA 4 datasets

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 208 bp overlap

ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 172 bp overlap

ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 206 bp overlap

RNF2 1 dataset

ChIP SYO-1_shCt GSE139053.RNF2.SYO-1_shCt 221 bp overlap

RXRB 2 datasets

Motif DE_12h DE_12h-RXRB_MA1555.1 14 bp overlap

Motif ES_0h ES_0h-RXRB_MA1555.1 14 bp overlap

RXRG 2 datasets

Motif DE_12h DE_12h-RXRG_MA1556.1 14 bp overlap

Motif ES_0h ES_0h-RXRG_MA1556.1 14 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 221 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 175 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 159 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 221 bp overlap

SP2 4 datasets

ChIP HEK293 ENCFF181QXT 221 bp overlap

ChIP HEK293 ENCSR807LQP.SP2.HEK293 221 bp overlap

ChIP HEK293 GSE76494.SP2.HEK293 221 bp overlap

ChIP HEK293T ERP007114.SP2.HEK293T 221 bp overlap

SP4 2 datasets

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 221 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SP8 1 dataset

Motif DE_12h DE_12h-SP8_MA0747.2 11 bp overlap

SUZ12 1 dataset

ChIP LNCaP-abl GSE39459.SUZ12.LNCaP-abl 114 bp overlap

TBP 1 dataset

ChIP hESC_8h GSE122298.TBP.hESC_8h 187 bp overlap

TBX1 2 datasets

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap

TBX15 2 datasets

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap

TBX5 2 datasets

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap

Tcf12 1 dataset

Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap

ZKSCAN3 1 dataset

Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF18 1 dataset

ChIP HEK293 GSE76494.ZNF18.HEK293 145 bp overlap

ZNF350 1 dataset

ChIP HEK293 GSE76494.ZNF350.HEK293 169 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 221 bp overlap