chr8:38,015,136–38,015,926

chr8 : 38,015,136 – 38,015,926

790 bp 59 TFs 10 linked genes

This 790 bp open chromatin element is linked to 10 target genes and is bound by 59 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
EIF4EBP1		15.0 kb	Distal	Multiome
ASH2L		90.0 kb	Distal	Multiome
RAB11FIP1		116.0 kb	Distal	Multiome
LSM1		161.2 kb	Distal	Multiome
BAG4		161.3 kb	Distal	Multiome
BRF2		165.7 kb	Distal	Multiome
DDHD2		216.1 kb	Distal	Multiome
PLPBP		252.9 kb	Distal	Multiome
PLPP5		253.7 kb	Distal	Multiome
ERLIN2		278.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

59 transcription factors

ChIP MCF-7 ERP001226.AR.MCF-7 201 bp overlap

ARID1A 1 dataset

ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 483 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 372 bp overlap

ChIP K562 ENCFF938UXQ 324 bp overlap

ChIP K-562 ENCSR808AKZ.BCOR.K-562 247 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 211 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 335 bp overlap

ChIP K562 ENCFF963TXY 149 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 435 bp overlap

ChIP K562 ENCFF673OEZ 323 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 157 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 244 bp overlap

ChIP K562 ENCFF403WPG 545 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF031ISE 50 bp overlap

ChIP BLaER1 ENCFF364PUR 281 bp overlap

ChIP BLaER1 ENCFF460KDD 79 bp overlap

ChIP BLaER1 ENCFF460KDD 168 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 145 bp overlap

ChIP K562 ENCFF775HUO 219 bp overlap

EP300 1 dataset

ChIP K562 ENCFF226VMS 317 bp overlap

ESR1 16 datasets

ChIP MCF-7 GSE103023.ESR1.MCF-7 263 bp overlap

ChIP MCF-7 GSE41561.ESR1.MCF-7 199 bp overlap

ChIP MCF-7 GSE76893.ESR1.MCF-7 177 bp overlap

ChIP MCF-7 GSE68355.ESR1.MCF-7 253 bp overlap

ChIP MCF-7 GSE95302.ESR1.MCF-7 222 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 126 bp overlap

ChIP MCF-7_E2+4OHT GSE119702.ESR1.MCF-7_E2+4OHT 277 bp overlap

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 326 bp overlap

ChIP MCF-7_OHT GSE119702.ESR1.MCF-7_OHT 277 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 310 bp overlap

ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 286 bp overlap

ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 240 bp overlap

ChIP MCF-7_SICTR_E2 GSE40129.ESR1.MCF-7_SICTR_E2 127 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 326 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 221 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 246 bp overlap

FOXA1 6 datasets

ChIP MCF-7 ERP001226.FOXA1.MCF-7 224 bp overlap

ChIP MCF-7_1117 GSE124667.FOXA1.MCF-7_1117 158 bp overlap

ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 139 bp overlap

ChIP MCF-7_E2_TAM ERP000380.FOXA1.MCF-7_E2_TAM 198 bp overlap

ChIP MCF-7_JC4692 GSE126004.FOXA1.MCF-7_JC4692 181 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 220 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 776 bp overlap

ChIP DE DE-FOXA2-2 790 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 204 bp overlap

GATA1 6 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 55 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 229 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 128 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 147 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 304 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

GATA2 1 dataset

ChIP K562 ENCFF544PCK 251 bp overlap

GATA3 2 datasets

ChIP MCF-7 GSE133072.GATA3.MCF-7 195 bp overlap

ChIP MCF-7_E2 GSE40129.GATA3.MCF-7_E2 134 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 740 bp overlap

ChIP DE DE-GATA4-2 790 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 326 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 431 bp overlap

GATA6 12 datasets

ChIP AGS GSE51705.GATA6.AGS 143 bp overlap

ChIP DE DE-GATA6-1 630 bp overlap

ChIP DE DE-GATA6-2 760 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 591 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 582 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 617 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 691 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 524 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 589 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 480 bp overlap

ChIP foregut GSE117136.GATA6.foregut 388 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 424 bp overlap

GRHL2 1 dataset

ChIP MCF-7 GSE109820.GRHL2.MCF-7 173 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 438 bp overlap

ChIP K-562 ENCSR711VWL.HDAC1.K-562 266 bp overlap

ChIP K562 ENCFF968WBH 254 bp overlap

HDAC2 3 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 663 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 239 bp overlap

ChIP K562 ENCFF744ALD 197 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 467 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 400 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 464 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 434 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 432 bp overlap

KDM1A 5 datasets

ChIP K-562 ENCSR908CMW.KDM1A.K-562 566 bp overlap

ChIP K-562 ENCSR360HRA.KDM1A.K-562 364 bp overlap

ChIP K562 ENCFF128TYE 461 bp overlap

ChIP K562 ENCFF133OLU 461 bp overlap

ChIP K562 ENCFF133OLU 349 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 134 bp overlap

MEIS2 1 dataset

ChIP K-562 ENCSR851BNE.MEIS2.K-562 214 bp overlap

ChIP K-562 ENCSR807BGP.MTA1.K-562 203 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 442 bp overlap

NCOR1 1 dataset

ChIP K562 ENCFF866HRM 445 bp overlap

ChIP K-562 ENCSR000FCC.NFE2.K-562 145 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 222 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 120 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 548 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 495 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 204 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP K562 ENCFF653BQJ 611 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 212 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 177 bp overlap

SMAD2 3 datasets

ChIP endoderm GSE29422.SMAD2.endoderm 180 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 637 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 471 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 658 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 708 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 636 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 733 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 740 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 727 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 725 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 735 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 446 bp overlap

SMARCA5 1 dataset

ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 253 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 377 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 392 bp overlap

SMARCE1 2 datasets

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 331 bp overlap

ChIP K562 ENCFF690CFF 166 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 422 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 637 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 313 bp overlap

ChIP K562 ENCFF059YCJ 437 bp overlap

TAL1 6 datasets

ChIP K-562 ENCSR106FRG.TAL1.K-562 307 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 183 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 176 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 185 bp overlap

ChIP K562 ENCFF620GMX 238 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 257 bp overlap

ChIP K562 ENCFF931DJY 391 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 135 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 365 bp overlap

TRPS1 1 dataset

ChIP MCF-7 GSE133072.TRPS1.MCF-7 351 bp overlap

ZEB2 4 datasets

ChIP K-562 ENCSR004GKA.ZEB2.K-562 540 bp overlap

ChIP K-562 ENCSR322CFO.ZEB2.K-562 218 bp overlap

ChIP K562 ENCFF795CMH 256 bp overlap

ChIP K562 ENCFF975RXS 461 bp overlap

ChIP K562 ENCFF536AJO 308 bp overlap

ZMYM3 1 dataset

ChIP K-562_Ab_JH39-2-2F10 GSE97661.ZMYM3.K-562_Ab_JH39-2-2F10 191 bp overlap

ZNF460 1 dataset

ChIP HepG2 ENCFF007NNM 349 bp overlap