chr7 : 83,666,258 – 83,667,242
984 bp 80 TFs 1 linked gene
This 984 bp open chromatin element is linked to SEMA3E and is bound by 80 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SEMA3E 17.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr7:83,661,258 – 83,672,242
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
80 transcription factors
Source
Cell type
AR 1 dataset
ChIP VCaP_Veh GSE125245.AR.VCaP_Veh 181 bp overlap
Arid3a 5 datasets
Motif DE_48h DE_48h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap
Motif DE_72h DE_72h-Arid3a_MA0151.1 6 bp overlap
BRD4 1 dataset
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 532 bp overlap
CLOCK 1 dataset
ChIP BA40_3 GSE96659.CLOCK.BA40_3 150 bp overlap
CTCF 1 dataset
Motif DE_60h DE_60h-CTCF_MA1930.2 33 bp overlap
EGR1 3 datasets
Motif DE_48h DE_48h-EGR1_MA0162.5 10 bp overlap
Motif DE_60h DE_60h-EGR1_MA0162.5 10 bp overlap
Motif DE_72h DE_72h-EGR1_MA0162.5 10 bp overlap
EGR4 3 datasets
Motif DE_48h DE_48h-EGR4_MA0733.2 11 bp overlap
Motif DE_60h DE_60h-EGR4_MA0733.2 11 bp overlap
Motif DE_72h DE_72h-EGR4_MA0733.2 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 407 bp overlap
ERF::NHLH1 1 dataset
Motif DE_60h DE_60h-ERFNHLH1_MA1938.2 16 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 635 bp overlap
ChIP DE DE-FOXA2-2 696 bp overlap
FOXE1 2 datasets
Motif DE_48h DE_48h-FOXE1_MA1487.3 12 bp overlap
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
GATA2 4 datasets
Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 280 bp overlap
GATA4 6 datasets
ChIP DE DE-GATA4-1 678 bp overlap
ChIP DE DE-GATA4-2 800 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP foregut GSE117136.GATA4.foregut 314 bp overlap
GATA5 3 datasets
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap
GATA6 13 datasets
ChIP DE DE-GATA6-1 638 bp overlap
ChIP DE DE-GATA6-2 887 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 335 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 732 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 398 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 331 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 591 bp overlap
ChIP foregut GSE117136.GATA6.foregut 279 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 446 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 264 bp overlap
Gata3 3 datasets
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 260 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 529 bp overlap
HOXB4 1 dataset
Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap
HOXC4 1 dataset
Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap
HOXD4 1 dataset
Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap
HSF1 1 dataset
Motif DE_48h DE_48h-HSF1_MA0486.2 13 bp overlap
Hand1::Tcf3 3 datasets
Motif DE_48h DE_48h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap
IRF3 2 datasets
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
IRF4 2 datasets
Motif DE_60h DE_60h-IRF4_MA1419.2 14 bp overlap
Motif DE_72h DE_72h-IRF4_MA1419.2 14 bp overlap
IRF5 2 datasets
Motif DE_60h DE_60h-IRF5_MA1420.1 14 bp overlap
Motif DE_72h DE_72h-IRF5_MA1420.1 14 bp overlap
IRF7 2 datasets
Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap
Motif DE_72h DE_72h-IRF7_MA0772.2 13 bp overlap
IRF8 2 datasets
Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap
Motif DE_72h DE_72h-IRF8_MA0652.2 13 bp overlap
IRF9 2 datasets
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
ISL1 1 dataset
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 531 bp overlap
ISL2 1 dataset
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
Irf1 2 datasets
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
KLF16 3 datasets
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap
Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap
Lhx3 2 datasets
Motif DE_60h DE_60h-Lhx3_MA0135.2 12 bp overlap
Motif DE_72h DE_72h-Lhx3_MA0135.2 12 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MYOG 1 dataset
ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 181 bp overlap
Mecom 3 datasets
Motif DE_48h DE_48h-Mecom_MA0029.2 11 bp overlap
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
Motif DE_72h DE_72h-Mecom_MA0029.2 11 bp overlap
NKX6-1 1 dataset
Motif DE_48h DE_48h-NKX6-1_MA0674.2 7 bp overlap
NR1H4::RXRA 1 dataset
Motif DE_60h DE_60h-NR1H4RXRA_MA1146.2 13 bp overlap
NR2F2 1 dataset
ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 161 bp overlap
NR4A2::RXRA 1 dataset
Motif DE_60h DE_60h-NR4A2RXRA_MA1147.2 13 bp overlap
OLIG2 1 dataset
Motif DE_60h DE_60h-OLIG2_MA0678.1 10 bp overlap
OLIG3 1 dataset
Motif DE_60h DE_60h-OLIG3_MA0827.1 10 bp overlap
PBX3 3 datasets
Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap
Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap
Motif DE_72h DE_72h-PBX3_MA1114.2 11 bp overlap
PHOX2A 1 dataset
Motif DE_48h DE_48h-PHOX2A_MA0713.1 11 bp overlap
PHOX2B 3 datasets
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 377 bp overlap
Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 426 bp overlap
PLAG1 2 datasets
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap
PRDM1 3 datasets
Motif DE_60h DE_60h-PRDM1_MA0508.4 7 bp overlap
Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap
ChIP fetal_testis GSE100639.PRDM1.fetal_testis 155 bp overlap
PROP1 1 dataset
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Pgr 2 datasets
Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap
Motif DE_72h DE_72h-Pgr_MA2323.1 17 bp overlap
Prdm4 3 datasets
Motif DE_48h DE_48h-Prdm4_MA1647.3 11 bp overlap
Motif DE_60h DE_60h-Prdm4_MA1647.3 11 bp overlap
Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap
SIX1 3 datasets
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
Motif DE_72h DE_72h-SIX1_MA1118.2 9 bp overlap
SIX2 3 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
Motif DE_72h DE_72h-SIX2_MA1119.2 11 bp overlap
SMAD1 1 dataset
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 580 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 496 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 590 bp overlap
SMARCA4 1 dataset
ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 238 bp overlap
SOX15 2 datasets
Motif DE_60h DE_60h-SOX15_MA1152.2 7 bp overlap
Motif DE_72h DE_72h-SOX15_MA1152.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 493 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 629 bp overlap
SP8 3 datasets
Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap
Motif DE_60h DE_60h-SP8_MA0747.2 11 bp overlap
Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap
STAT1::STAT2 2 datasets
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
STAT3 1 dataset
Motif DE_48h DE_48h-STAT3_MA0144.3 9 bp overlap
Stat2 2 datasets
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 416 bp overlap
TBX2 1 dataset
ChIP SK-N-BE2-C GSE94822.TBX2.SK-N-BE2-C 178 bp overlap
TCF4 2 datasets
ChIP SK-N-SH ENCFF270OWF 437 bp overlap
ChIP SK-N-SH ENCFF270OWF 437 bp overlap
TEAD1 1 dataset
Motif DE_60h DE_60h-TEAD1_MA0090.4 9 bp overlap
TFCP2 3 datasets
Motif DE_48h DE_48h-TFCP2_MA1968.2 9 bp overlap
Motif DE_60h DE_60h-TFCP2_MA1968.2 9 bp overlap
Motif DE_72h DE_72h-TFCP2_MA1968.2 9 bp overlap
TOX2 1 dataset
ChIP SK-N-SH ENCFF415OYE 297 bp overlap
TRPS1 3 datasets
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 243 bp overlap
ZNF281 3 datasets
Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap
Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF416 2 datasets
Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap
Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap
ZNF528 4 datasets
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
Motif DE_48h DE_48h-ZNF528_MA1597.1 17 bp overlap
Motif DE_60h DE_60h-ZNF528_MA1597.1 17 bp overlap
Motif DE_72h DE_72h-ZNF528_MA1597.1 17 bp overlap
ZNF582 3 datasets
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
Motif DE_60h DE_60h-ZNF582_MA1983.2 19 bp overlap
Motif DE_72h DE_72h-ZNF582_MA1983.2 19 bp overlap
ZNF675 3 datasets
Motif DE_48h DE_48h-ZNF675_MA1714.2 19 bp overlap
Motif DE_60h DE_60h-ZNF675_MA1714.2 19 bp overlap
Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap
ZNF680 3 datasets
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF768 2 datasets
Motif DE_60h DE_60h-ZNF768_MA1731.2 9 bp overlap
Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap
ZNF770 1 dataset
Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap
ZSCAN21 3 datasets
Motif DE_48h DE_48h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_60h DE_60h-ZSCAN21_MA2336.1 7 bp overlap
Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap
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