chr6:169,656,289–169,657,223

chr6 : 169,656,289 – 169,657,223

934 bp 87 TFs 6 linked genes

This 934 bp open chromatin element is linked to 6 target genes and is bound by 87 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
WDR27		45.3 kb	Distal	Multiome
C6orf120		45.4 kb	Distal	Multiome
PHF10		67.8 kb	Distal	Multiome
ENSG00000227704		68.0 kb	Distal	Multiome
ERMARD		94.9 kb	Distal	Multiome
ENSG00000272848		204.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

87 transcription factors

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 239 bp overlap

CTCF 5 datasets

Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap

Motif DE_36h DE_36h-CTCF_MA0139.2 15 bp overlap

Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 190 bp overlap

ChIP THP-1_Pam3csk-020m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-020m-Flavo-000m 161 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF262VBH 356 bp overlap

ChIP BLaER1 ENCFF274GAT 245 bp overlap

DNMT3B 2 datasets

ChIP HUES-8 GSE99346.DNMT3B.HUES-8 519 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 403 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 260 bp overlap

EOMES 3 datasets

Motif DE_24h DE_24h-EOMES_MA0800.2 9 bp overlap

Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap

ChIP hESC GSE26097.EOMES.hESC 154 bp overlap

ESR1 2 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 87 bp overlap

ChIP NCI-H3396_E2 GSE32349.ESR1.NCI-H3396_E2 97 bp overlap

Motif DE_24h DE_24h-ESR2_MA0258.2 15 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 72 bp overlap

Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap

Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap

FEZF2 1 dataset

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 332 bp overlap

FOXO1::ELF1 1 dataset

Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 1 dataset

Motif DE_24h DE_24h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 1 dataset

Motif DE_24h DE_24h-FOXO1ELK3_MA1955.2 13 bp overlap

FOXO1::FLI1 1 dataset

Motif DE_24h DE_24h-FOXO1FLI1_MA1956.2 13 bp overlap

GABPA 2 datasets

Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap

Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 125 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 266 bp overlap

HIC2 2 datasets

Motif DE_24h DE_24h-HIC2_MA0738.2 6 bp overlap

Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 63 bp overlap

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 222 bp overlap

ChIP 786-O GSE86092.JUN.786-O 177 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

KLF11 2 datasets

Motif DE_24h DE_24h-KLF11_MA1512.2 10 bp overlap

Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap

KLF9 2 datasets

Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap

Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 205 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 214 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 181 bp overlap

Motif DE_24h DE_24h-MGA_MA0801.1 8 bp overlap

Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap

Motif DE_24h DE_24h-Mafg_MA0659.4 12 bp overlap

Mecom 1 dataset

Motif DE_24h DE_24h-Mecom_MA0029.2 11 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 406 bp overlap

PARP1 1 dataset

ChIP MCF-10A GSE93038.PARP1.MCF-10A 401 bp overlap

ChIP NALM-6 GSE126300.PAX5.NALM-6 237 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 597 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 150 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 209 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 277 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 798 bp overlap

PRDM9 2 datasets

Motif DE_24h DE_24h-PRDM9_MA1723.2 20 bp overlap

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 368 bp overlap

ChIP CD4 GSE49570.REST.CD4 152 bp overlap

RUNX1 1 dataset

ChIP NALM-6 GSE126300.RUNX1.NALM-6 243 bp overlap

RUNX2 1 dataset

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 167 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 672 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 188 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 402 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 776 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 159 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 131 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 287 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 713 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 649 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 372 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 616 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 916 bp overlap

ChIP HNSC GSE69479.SOX2.HNSC 396 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 183 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 271 bp overlap

TBR1 2 datasets

Motif DE_24h DE_24h-TBR1_MA0802.2 9 bp overlap

Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap

TBX1 2 datasets

Motif DE_24h DE_24h-TBX1_MA0805.1 8 bp overlap

Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap

TBX15 2 datasets

Motif DE_24h DE_24h-TBX15_MA0803.1 8 bp overlap

Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap

TBX18 2 datasets

Motif DE_24h DE_24h-TBX18_MA1565.2 9 bp overlap

Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap

TBX19 2 datasets

Motif DE_24h DE_24h-TBX19_MA0804.2 17 bp overlap

Motif DE_48h DE_48h-TBX19_MA0804.2 17 bp overlap

TBX2 2 datasets

Motif DE_24h DE_24h-TBX2_MA0688.2 9 bp overlap

Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap

TBX20 2 datasets

Motif DE_24h DE_24h-TBX20_MA0689.1 11 bp overlap

Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap

TBX21 2 datasets

Motif DE_24h DE_24h-TBX21_MA0690.3 10 bp overlap

Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap

TBX3 2 datasets

Motif DE_24h DE_24h-TBX3_MA1566.3 9 bp overlap

Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap

TBX5 3 datasets

Motif DE_24h DE_24h-TBX5_MA0807.1 8 bp overlap

Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 152 bp overlap

TBXT 2 datasets

Motif DE_24h DE_24h-TBXT_MA0009.2 16 bp overlap

Motif DE_48h DE_48h-TBXT_MA0009.2 16 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 304 bp overlap

TFAP2A 2 datasets

Motif DE_24h DE_24h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_48h DE_48h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 2 datasets

Motif DE_24h DE_24h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_48h DE_48h-TFAP2B_MA0811.2 11 bp overlap

TFAP2C 2 datasets

Motif DE_24h DE_24h-TFAP2C_MA0524.3 11 bp overlap

Motif DE_48h DE_48h-TFAP2C_MA0524.3 11 bp overlap

TP63 2 datasets

ChIP breast-organoid GSE113909.TP63.breast-organoid 113 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 66 bp overlap

TRIM28 2 datasets

ChIP AF22 GSE84259.TRIM28.AF22 500 bp overlap

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 477 bp overlap

Tbx6 2 datasets

Motif DE_24h DE_24h-Tbx6_MA1567.3 9 bp overlap

Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap

Tfcp2l1 1 dataset

Motif DE_24h DE_24h-Tfcp2l1_MA0145.2 14 bp overlap

Thap11 6 datasets

Motif DE_24h DE_24h-Thap11_MA1573.2 14 bp overlap

Motif DE_24h DE_24h-Thap11_MA1573.2 14 bp overlap

Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap

Motif DE_36h DE_36h-Thap11_MA1573.2 14 bp overlap

Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap

Motif DE_48h DE_48h-Thap11_MA1573.2 14 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 97 bp overlap

ZBED4 3 datasets

Motif DE_24h DE_24h-ZBED4_MA2328.1 10 bp overlap

Motif DE_36h DE_36h-ZBED4_MA2328.1 10 bp overlap

Motif DE_48h DE_48h-ZBED4_MA2328.1 10 bp overlap

ZBTB48 2 datasets

ChIP U2OS GSE96776.ZBTB48.U2OS 305 bp overlap

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 599 bp overlap

ZFP42 2 datasets

Motif DE_24h DE_24h-ZFP42_MA1651.2 13 bp overlap

Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 502 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 104 bp overlap

ZKSCAN3 1 dataset

Motif DE_24h DE_24h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF135 1 dataset

Motif DE_24h DE_24h-ZNF135_MA1587.1 14 bp overlap

ZNF16 3 datasets

Motif DE_24h DE_24h-ZNF16_MA1654.2 21 bp overlap

Motif DE_36h DE_36h-ZNF16_MA1654.2 21 bp overlap

Motif DE_48h DE_48h-ZNF16_MA1654.2 21 bp overlap

ZNF281 1 dataset

Motif DE_24h DE_24h-ZNF281_MA1630.3 10 bp overlap

ZNF320 1 dataset

Motif DE_24h DE_24h-ZNF320_MA1976.2 20 bp overlap

ZNF460 1 dataset

Motif DE_24h DE_24h-ZNF460_MA1596.1 16 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 243 bp overlap

ZNF692 1 dataset

Motif DE_24h DE_24h-ZNF692_MA1986.2 8 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 151 bp overlap

ZNF770 1 dataset

Motif DE_24h DE_24h-ZNF770_MA2099.1 8 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 192 bp overlap

ZNF93 2 datasets

Motif DE_24h DE_24h-ZNF93_MA1721.2 14 bp overlap

Motif DE_48h DE_48h-ZNF93_MA1721.2 14 bp overlap

ZSCAN16 1 dataset

Motif DE_24h DE_24h-ZSCAN16_MA2100.1 18 bp overlap

Zfp809 2 datasets

Motif DE_24h DE_24h-Zfp809_MA2125.1 9 bp overlap

Motif DE_24h DE_24h-Zfp809_MA2125.1 9 bp overlap

Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap

Motif DE_48h DE_48h-Zfx_MA0146.3 10 bp overlap