chr6 : 163,008,143 – 163,009,245
1,102 bp 86 TFs 1 linked gene
This 1.1 kb open chromatin element is linked to PRKN and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PRKN 281.0 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:163,003,143 – 163,014,245
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
ARNT::HIF1A 2 datasets
Motif DE_36h DE_36h-ARNTHIF1A_MA0259.2 5 bp overlap
Motif DE_60h DE_60h-ARNTHIF1A_MA0259.2 5 bp overlap
BCL3 2 datasets
ChIP GM12878 ENCFF854PAY 247 bp overlap
ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 175 bp overlap
BCL6 2 datasets
Motif DE_36h DE_36h-BCL6_MA0463.3 13 bp overlap
Motif DE_60h DE_60h-BCL6_MA0463.3 13 bp overlap
Dux 3 datasets
Motif DE_36h DE_36h-Dux_MA0611.3 11 bp overlap
Motif DE_48h DE_48h-Dux_MA0611.3 11 bp overlap
Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 333 bp overlap
ERG 2 datasets
ChIP VCaP GSE49091.ERG.VCaP 147 bp overlap
ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 149 bp overlap
ETS1 4 datasets
ChIP HUVEC-C GSE41166.ETS1.HUVEC-C 190 bp overlap
ChIP HUVEC-C GSE109625.ETS1.HUVEC-C 252 bp overlap
ChIP HUVEC-C GSE93030.ETS1.HUVEC-C 252 bp overlap
ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 233 bp overlap
EZH2_phosphoT487 1 dataset
ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 213 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 1024 bp overlap
ChIP DE DE-FOXA2-2 928 bp overlap
FOXD3 1 dataset
Motif DE_36h DE_36h-FOXD3_MA0041.3 14 bp overlap
FOXN3 4 datasets
Motif DE_36h DE_36h-FOXN3_MA1489.1 8 bp overlap
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_36h DE_36h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1FLI1_MA1956.2 13 bp overlap
Foxq1 4 datasets
Motif DE_36h DE_36h-Foxq1_MA0040.2 10 bp overlap
Motif DE_48h DE_48h-Foxq1_MA0040.2 10 bp overlap
Motif DE_60h DE_60h-Foxq1_MA0040.2 10 bp overlap
Motif DE_72h DE_72h-Foxq1_MA0040.2 10 bp overlap
GATA1 2 datasets
Motif DE_36h DE_36h-GATA1_MA0035.5 7 bp overlap
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 740 bp overlap
ChIP DE DE-GATA4-2 877 bp overlap
Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 290 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 684 bp overlap
ChIP DE DE-GATA6-2 859 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 267 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 634 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 365 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 661 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 732 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 435 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 479 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 309 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 290 bp overlap
GLIS1 2 datasets
Motif DE_36h DE_36h-GLIS1_MA0735.2 15 bp overlap
Motif DE_60h DE_60h-GLIS1_MA0735.2 15 bp overlap
Gfi1B 3 datasets
Motif DE_36h DE_36h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_48h DE_48h-Gfi1B_MA0483.2 10 bp overlap
Motif DE_60h DE_60h-Gfi1B_MA0483.2 10 bp overlap
HIF1A 1 dataset
ChIP macrophage_HYPO GSE43109.HIF1A.macrophage_HYPO 79 bp overlap
HOXA9 1 dataset
ChIP HEK293-FT GSE62586.HOXA9.HEK293-FT 84 bp overlap
Hand1::Tcf3 2 datasets
Motif DE_36h DE_36h-Hand1Tcf3_MA0092.2 9 bp overlap
Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap
Hic1 3 datasets
Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap
Motif DE_48h DE_48h-Hic1_MA0739.2 8 bp overlap
Motif DE_60h DE_60h-Hic1_MA0739.2 8 bp overlap
IRF3 6 datasets
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
Motif DE_36h DE_36h-IRF3_MA1418.2 17 bp overlap
Motif DE_48h DE_48h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Motif DE_72h DE_72h-IRF3_MA1418.2 17 bp overlap
IRF4 4 datasets
Motif DE_36h DE_36h-IRF4_MA1419.2 14 bp overlap
Motif DE_48h DE_48h-IRF4_MA1419.2 14 bp overlap
Motif DE_60h DE_60h-IRF4_MA1419.2 14 bp overlap
Motif DE_72h DE_72h-IRF4_MA1419.2 14 bp overlap
IRF7 4 datasets
Motif DE_36h DE_36h-IRF7_MA0772.2 13 bp overlap
Motif DE_48h DE_48h-IRF7_MA0772.2 13 bp overlap
Motif DE_60h DE_60h-IRF7_MA0772.2 13 bp overlap
Motif DE_72h DE_72h-IRF7_MA0772.2 13 bp overlap
IRF8 4 datasets
Motif DE_36h DE_36h-IRF8_MA0652.2 13 bp overlap
Motif DE_48h DE_48h-IRF8_MA0652.2 13 bp overlap
Motif DE_60h DE_60h-IRF8_MA0652.2 13 bp overlap
Motif DE_72h DE_72h-IRF8_MA0652.2 13 bp overlap
IRF9 4 datasets
Motif DE_36h DE_36h-IRF9_MA0653.1 15 bp overlap
Motif DE_48h DE_48h-IRF9_MA0653.1 15 bp overlap
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
Motif DE_72h DE_72h-IRF9_MA0653.1 15 bp overlap
Irf1 4 datasets
Motif DE_36h DE_36h-Irf1_MA0050.4 11 bp overlap
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
LIN54 1 dataset
Motif DE_36h DE_36h-LIN54_MA0619.2 7 bp overlap
Lef1 1 dataset
Motif DE_36h DE_36h-Lef1_MA0768.3 8 bp overlap
MEF2A 1 dataset
Motif DE_36h DE_36h-MEF2A_MA0052.5 10 bp overlap
MEF2C 1 dataset
Motif DE_36h DE_36h-MEF2C_MA0497.2 11 bp overlap
MEIS1 5 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MGA::EVX1 2 datasets
Motif DE_36h DE_36h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
MXI1 2 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_60h DE_60h-MXI1_MA1108.3 6 bp overlap
NANOG 1 dataset
ChIP hESC GSE18292.NANOG.hESC 195 bp overlap
NFATC1 1 dataset
ChIP GM12878 ENCSR000BQL.NFATC1.GM12878 225 bp overlap
NFATC3 2 datasets
Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
NFIA 3 datasets
Motif DE_36h DE_36h-NFIA_MA0670.2 6 bp overlap
Motif DE_48h DE_48h-NFIA_MA0670.2 6 bp overlap
Motif DE_60h DE_60h-NFIA_MA0670.2 6 bp overlap
NFIX 3 datasets
Motif DE_36h DE_36h-NFIX_MA0671.2 6 bp overlap
Motif DE_48h DE_48h-NFIX_MA0671.2 6 bp overlap
Motif DE_60h DE_60h-NFIX_MA0671.2 6 bp overlap
NR1H2::RXRA 4 datasets
Motif DE_36h DE_36h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap
Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap
NR2C1 5 datasets
Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap
Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 5 datasets
Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap
Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F1 5 datasets
Motif DE_36h DE_36h-NR2F1_MA0017.3 12 bp overlap
Motif DE_36h DE_36h-NR2F1_MA1537.2 13 bp overlap
Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap
Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap
Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap
NR5A1 1 dataset
Motif DE_36h DE_36h-NR5A1_MA1540.3 12 bp overlap
Nfatc1 2 datasets
Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Nr1H2 5 datasets
Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 5 datasets
Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 5 datasets
Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr2e3 3 datasets
Motif DE_36h DE_36h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_48h DE_48h-Nr2e3_MA0164.2 6 bp overlap
Motif DE_60h DE_60h-Nr2e3_MA0164.2 6 bp overlap
Nr2f6 1 dataset
Motif DE_36h DE_36h-Nr2f6_MA0677.2 13 bp overlap
PAX6 4 datasets
Motif DE_36h DE_36h-PAX6_MA0069.1 14 bp overlap
Motif DE_48h DE_48h-PAX6_MA0069.1 14 bp overlap
Motif DE_60h DE_60h-PAX6_MA0069.1 14 bp overlap
Motif DE_72h DE_72h-PAX6_MA0069.1 14 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 630 bp overlap
PHOX2B 1 dataset
Motif DE_36h DE_36h-PHOX2B_MA0681.3 12 bp overlap
PPARD 4 datasets
Motif DE_36h DE_36h-PPARD_MA1550.2 14 bp overlap
Motif DE_48h DE_48h-PPARD_MA1550.2 14 bp overlap
Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap
Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap
PROP1 4 datasets
Motif DE_36h DE_36h-PROP1_MA0715.1 11 bp overlap
Motif DE_48h DE_48h-PROP1_MA0715.1 11 bp overlap
Motif DE_60h DE_60h-PROP1_MA0715.1 11 bp overlap
Motif DE_72h DE_72h-PROP1_MA0715.1 11 bp overlap
Pgr 2 datasets
Motif DE_36h DE_36h-Pgr_MA2323.1 17 bp overlap
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
RARB 3 datasets
Motif DE_36h DE_36h-RARB_MA1552.2 13 bp overlap
Motif DE_48h DE_48h-RARB_MA1552.2 13 bp overlap
Motif DE_60h DE_60h-RARB_MA1552.2 13 bp overlap
RARG 3 datasets
Motif DE_36h DE_36h-RARG_MA1553.2 13 bp overlap
Motif DE_48h DE_48h-RARG_MA1553.2 13 bp overlap
Motif DE_60h DE_60h-RARG_MA1553.2 13 bp overlap
REST 1 dataset
Motif DE_36h DE_36h-REST_MA0138.3 20 bp overlap
RXRB 5 datasets
Motif DE_36h DE_36h-RXRB_MA0855.1 14 bp overlap
Motif DE_36h DE_36h-RXRB_MA0855.1 14 bp overlap
Motif DE_48h DE_48h-RXRB_MA0855.1 14 bp overlap
Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 5 datasets
Motif DE_36h DE_36h-RXRG_MA0856.1 14 bp overlap
Motif DE_36h DE_36h-RXRG_MA0856.1 14 bp overlap
Motif DE_48h DE_48h-RXRG_MA0856.1 14 bp overlap
Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Rxra 5 datasets
Motif DE_36h DE_36h-Rxra_MA0512.2 14 bp overlap
Motif DE_36h DE_36h-Rxra_MA0512.2 14 bp overlap
Motif DE_48h DE_48h-Rxra_MA0512.2 14 bp overlap
Motif DE_60h DE_60h-Rxra_MA0512.2 14 bp overlap
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SIX1 2 datasets
Motif DE_36h DE_36h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 525 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 531 bp overlap
SMAD2_3 1 dataset
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 430 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 231 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 287 bp overlap
SOX2 1 dataset
ChIP hESC GSE18292.SOX2.hESC 98 bp overlap
SP5 2 datasets
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap
SPIB 2 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Motif DE_60h DE_60h-SPIB_MA0081.3 13 bp overlap
STAT1::STAT2 4 datasets
Motif DE_36h DE_36h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_60h DE_60h-STAT1STAT2_MA0517.2 13 bp overlap
Motif DE_72h DE_72h-STAT1STAT2_MA0517.2 13 bp overlap
Stat2 7 datasets
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_36h DE_36h-Stat2_MA1623.2 10 bp overlap
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_72h DE_72h-Stat2_MA1623.2 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 217 bp overlap
TCF7 1 dataset
Motif DE_36h DE_36h-TCF7_MA0769.3 7 bp overlap
TP73 4 datasets
Motif DE_36h DE_36h-TP73_MA0861.2 16 bp overlap
Motif DE_36h DE_36h-TP73_MA0861.2 16 bp overlap
Motif DE_48h DE_48h-TP73_MA0861.2 16 bp overlap
Motif DE_60h DE_60h-TP73_MA0861.2 16 bp overlap
ZBTB6 4 datasets
Motif DE_36h DE_36h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_72h DE_72h-ZBTB6_MA1581.2 9 bp overlap
ZFP14 2 datasets
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_60h DE_60h-ZFP14_MA1972.1 15 bp overlap
ZIC1 4 datasets
Motif DE_36h DE_36h-ZIC1_MA0696.1 14 bp overlap
Motif DE_48h DE_48h-ZIC1_MA0696.1 14 bp overlap
Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap
Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap
ZIM3 4 datasets
Motif DE_36h DE_36h-ZIM3_MA1709.2 11 bp overlap
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
Motif DE_72h DE_72h-ZIM3_MA1709.2 11 bp overlap
ZKSCAN5 2 datasets
Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap
Motif DE_60h DE_60h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF135 4 datasets
Motif DE_36h DE_36h-ZNF135_MA1587.1 14 bp overlap
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
Motif DE_60h DE_60h-ZNF135_MA1587.1 14 bp overlap
Motif DE_72h DE_72h-ZNF135_MA1587.1 14 bp overlap
ZNF331 1 dataset
Motif DE_60h DE_60h-ZNF331_MA1726.2 10 bp overlap
ZNF354A 3 datasets
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_36h DE_36h-ZNF354A_MA1978.2 20 bp overlap
Motif DE_60h DE_60h-ZNF354A_MA1978.2 20 bp overlap
ZNF667 2 datasets
Motif DE_36h DE_36h-ZNF667_MA1984.2 11 bp overlap
Motif DE_60h DE_60h-ZNF667_MA1984.2 11 bp overlap
ZNF766 4 datasets
Motif DE_36h DE_36h-ZNF766_MA2098.1 9 bp overlap
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap
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