chr1:114,037,114–114,037,804

chr1 : 114,037,114 – 114,037,804

690 bp 57 TFs 7 linked genes

This 690 bp open chromatin element is linked to 7 target genes and is bound by 57 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000282048		4.7 kb	Proximal	Proximity
OLFML3		57.8 kb	Distal	Multiome
HIPK1		107.6 kb	Distal	Multiome
SYT6		116.6 kb	Distal	Multiome+HiCAR
AP4B1		132.2 kb	Distal	Multiome
RSBN1		225.0 kb	Distal	Multiome
PHTF1		277.8 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

57 transcription factors

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 604 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 75 bp overlap

BCL6B 1 dataset

Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCFF432ZEW 247 bp overlap

ChIP H1 ENCFF785DWK 147 bp overlap

EGR1 2 datasets

Motif DE_12h DE_12h-EGR1_MA0162.5 10 bp overlap

Motif ES_0h ES_0h-EGR1_MA0162.5 10 bp overlap

EGR2 2 datasets

Motif DE_12h DE_12h-EGR2_MA0472.2 11 bp overlap

Motif ES_0h ES_0h-EGR2_MA0472.2 11 bp overlap

EGR3 2 datasets

Motif DE_12h DE_12h-EGR3_MA0732.2 11 bp overlap

Motif ES_0h ES_0h-EGR3_MA0732.2 11 bp overlap

EGR4 2 datasets

Motif DE_12h DE_12h-EGR4_MA0733.2 11 bp overlap

Motif ES_0h ES_0h-EGR4_MA0733.2 11 bp overlap

ESR1 12 datasets

ChIP MCF-7 GSE76893.ESR1.MCF-7 220 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 99 bp overlap

ChIP MCF-7_E2 GSE108883.ESR1.MCF-7_E2 52 bp overlap

ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 103 bp overlap

ChIP MCF-7_E2_45min GSE109820.ESR1.MCF-7_E2_45min 112 bp overlap

ChIP MCF-7_E2_90min GSE109820.ESR1.MCF-7_E2_90min 124 bp overlap

ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 154 bp overlap

ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 239 bp overlap

ChIP MCF-7_SHCRT_E2 ERP000380.ESR1.MCF-7_SHCRT_E2 121 bp overlap

ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 87 bp overlap

ChIP MDA-MB-134-VI_E2 GSE109103.ESR1.MDA-MB-134-VI_E2 64 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 171 bp overlap

ESR1_Y537S 1 dataset

ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 80 bp overlap

ETV6 2 datasets

ChIP GM12878 ENCSR597VGC.ETV6.GM12878 131 bp overlap

ChIP WTC11 ENCFF812SCD 213 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 124 bp overlap

FOXP4 2 datasets

ChIP WTC11 ENCFF708TAF 103 bp overlap

ChIP WTC11 ENCFF708TAF 319 bp overlap

GATA6 4 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 595 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 426 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 470 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 221 bp overlap

HOXB13 1 dataset

Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap

HOXC13 2 datasets

Motif DE_12h DE_12h-HOXC13_MA0907.2 9 bp overlap

Motif ES_0h ES_0h-HOXC13_MA0907.2 9 bp overlap

Hoxa13 1 dataset

Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 480 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 274 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 554 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 260 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 246 bp overlap

KLF11 2 datasets

Motif DE_12h DE_12h-KLF11_MA1512.2 10 bp overlap

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF13 2 datasets

Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap

Motif ES_0h ES_0h-KLF13_MA0657.2 17 bp overlap

KLF6 2 datasets

Motif DE_12h DE_12h-KLF6_MA1517.2 9 bp overlap

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

KLF9 2 datasets

Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

ChIP WTC11 ENCFF223QFY 271 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 129 bp overlap

NANOG 8 datasets

ChIP GM23338 ENCFF065NZG 103 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 441 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 103 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 183 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 126 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 127 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 120 bp overlap

NFE2L1 2 datasets

ChIP WTC11 ENCFF644BPU 125 bp overlap

ChIP WTC11 ENCFF644BPU 377 bp overlap

Nfat5 2 datasets

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Motif ES_0h ES_0h-Nfat5_MA0606.3 8 bp overlap

Nfatc2 2 datasets

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap

ONECUT2 1 dataset

ChIP A-549 GSE102599.ONECUT2.A-549 96 bp overlap

POLR2A 5 datasets

ChIP GM23338 ENCFF450WCS 273 bp overlap

ChIP GM23338 ENCFF450WCS 486 bp overlap

ChIP H1 ENCFF566JSR 190 bp overlap

ChIP H1 ENCFF566JSR 521 bp overlap

ChIP H1 ENCFF770YBQ 123 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 559 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 242 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 151 bp overlap

PPARG 2 datasets

Motif DE_12h DE_12h-PPARG_MA0066.2 19 bp overlap

Motif ES_0h ES_0h-PPARG_MA0066.2 19 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 248 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 165 bp overlap

ChIP H1 ENCFF263FUH 145 bp overlap

ChIP WTC11 ENCFF688PEU 459 bp overlap

Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP9_MA1564.2 10 bp overlap

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

Motif DE_12h DE_12h-TBP_MA0108.3 7 bp overlap

TCF12 1 dataset

ChIP H1 ENCFF203EBH 251 bp overlap

TEAD1 2 datasets

ChIP WTC11 ENCFF502QUV 165 bp overlap

ChIP WTC11 ENCFF502QUV 365 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 210 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 196 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 140 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 401 bp overlap

ZIC1 2 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZIC4 2 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif ES_0h ES_0h-ZIC4_MA0751.2 14 bp overlap

ZIC5 2 datasets

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

Motif ES_0h ES_0h-ZIC5_MA1584.2 15 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCFF631OSW 258 bp overlap

ZNF157 2 datasets

Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap

Motif ES_0h ES_0h-ZNF157_MA2331.1 21 bp overlap

ZNF184 2 datasets

ChIP WTC11 ENCFF352POG 382 bp overlap

ChIP WTC11 ENCFF352POG 497 bp overlap

ZNF324 2 datasets

Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap

Motif ES_0h ES_0h-ZNF324_MA1977.2 14 bp overlap

ZNF341 1 dataset

Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap

ZNF784 2 datasets

Motif DE_12h DE_12h-ZNF784_MA1717.2 8 bp overlap

Motif ES_0h ES_0h-ZNF784_MA1717.2 8 bp overlap

Zfp335 2 datasets

Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap

Motif ES_0h ES_0h-Zfp335_MA2002.2 7 bp overlap