chr5:126,839,262–126,839,804

chr5 : 126,839,262 – 126,839,804

542 bp 90 TFs 6 linked genes

This 542 bp open chromatin element is linked to 6 target genes and is bound by 90 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LMNB1		62.5 kb	Distal	Multiome
MARCHF3		191.0 kb	Distal	Multiome+HiCAR
C5orf63		233.9 kb	Distal	Multiome+HiCAR
PHAX		238.7 kb	Distal	Multiome
ALDH7A1		244.4 kb	Distal	Multiome
MEGF10		451.2 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BCL6B 2 datasets

Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap

Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap

CEBPD 2 datasets

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

Motif ES_0h ES_0h-CEBPD_MA0836.3 8 bp overlap

CREB1 2 datasets

Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap

ChIP GM23338 ENCFF432ZEW 305 bp overlap

DUX4 2 datasets

Motif DE_12h DE_12h-DUX4_MA0468.1 11 bp overlap

Motif ES_0h ES_0h-DUX4_MA0468.1 11 bp overlap

E2F8 2 datasets

Motif DE_12h DE_12h-E2F8_MA0865.3 9 bp overlap

Motif ES_0h ES_0h-E2F8_MA0865.3 9 bp overlap

ELK1::HOXA1 2 datasets

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

Motif ES_0h ES_0h-ELK1HOXA1_MA1931.1 14 bp overlap

ELK1::HOXB13 2 datasets

Motif DE_12h DE_12h-ELK1HOXB13_MA1932.2 15 bp overlap

Motif ES_0h ES_0h-ELK1HOXB13_MA1932.2 15 bp overlap

ETV5::HOXA2 2 datasets

Motif DE_12h DE_12h-ETV5HOXA2_MA1948.2 12 bp overlap

Motif ES_0h ES_0h-ETV5HOXA2_MA1948.2 12 bp overlap

EWSR1-FLI1 1 dataset

Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 534 bp overlap

ChIP DE DE-FOXA2-2 512 bp overlap

GATA2 1 dataset

Motif DE_12h DE_12h-GATA2_MA0036.4 7 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 542 bp overlap

ChIP DE DE-GATA4-2 542 bp overlap

Motif DE_12h DE_12h-GATA4_MA0482.3 8 bp overlap

GATA5 1 dataset

Motif DE_12h DE_12h-GATA5_MA0766.3 8 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-1 506 bp overlap

ChIP DE DE-GATA6-2 542 bp overlap

Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 369 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 460 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 265 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 249 bp overlap

GLIS1 2 datasets

Motif DE_12h DE_12h-GLIS1_MA0735.2 15 bp overlap

Motif ES_0h ES_0h-GLIS1_MA0735.2 15 bp overlap

GLIS3 2 datasets

Motif DE_12h DE_12h-GLIS3_MA0737.1 14 bp overlap

Motif ES_0h ES_0h-GLIS3_MA0737.1 14 bp overlap

Gata3 1 dataset

Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap

Gli2 3 datasets

Motif DE_12h DE_12h-Gli2_MA0734.4 9 bp overlap

Motif DE_24h DE_24h-Gli2_MA0734.4 9 bp overlap

Motif ES_0h ES_0h-Gli2_MA0734.4 9 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

HMBOX1 2 datasets

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

Motif ES_0h ES_0h-HMBOX1_MA0895.2 7 bp overlap

HOXB13 2 datasets

Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap

Motif DE_24h DE_24h-HOXB13_MA0901.3 9 bp overlap

HOXB2::ELK1 2 datasets

Motif DE_12h DE_12h-HOXB2ELK1_MA1957.1 14 bp overlap

Motif ES_0h ES_0h-HOXB2ELK1_MA1957.1 14 bp overlap

Hmx2 2 datasets

Motif DE_12h DE_12h-Hmx2_MA0897.2 15 bp overlap

Motif ES_0h ES_0h-Hmx2_MA0897.2 15 bp overlap

Hmx3 2 datasets

Motif DE_12h DE_12h-Hmx3_MA0898.2 9 bp overlap

Motif ES_0h ES_0h-Hmx3_MA0898.2 9 bp overlap

Hnf1A 1 dataset

Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap

Hoxa13 2 datasets

Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap

Motif DE_24h DE_24h-Hoxa13_MA0650.4 8 bp overlap

ISL2 2 datasets

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

Motif ES_0h ES_0h-ISL2_MA0914.2 6 bp overlap

Motif DE_12h DE_12h-JUN_MA0488.2 10 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 322 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 315 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 349 bp overlap

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_12h DE_12h-MAFF_MA0495.4 11 bp overlap

Motif DE_12h DE_12h-MAFK_MA0496.4 10 bp overlap

Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap

MEIS1 3 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

MGA::EVX1 2 datasets

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

Motif ES_0h ES_0h-MGAEVX1_MA1960.2 11 bp overlap

Motif DE_12h DE_12h-Mafb_MA0117.3 11 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 125 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 525 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 184 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 162 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 472 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 215 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NR2F1 3 datasets

Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap

Motif DE_24h DE_24h-NR2F1_MA0017.3 12 bp overlap

Motif ES_0h ES_0h-NR2F1_MA0017.3 12 bp overlap

Motif DE_12h DE_12h-NRL_MA0842.3 12 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

Nfat5 2 datasets

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap

Nfatc2 2 datasets

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap

Nkx3-2 2 datasets

Motif DE_12h DE_12h-Nkx3-2_MA0122.4 10 bp overlap

Motif ES_0h ES_0h-Nkx3-2_MA0122.4 10 bp overlap

Nr1h3::Rxra 2 datasets

Motif DE_12h DE_12h-Nr1h3Rxra_MA0494.2 16 bp overlap

Motif ES_0h ES_0h-Nr1h3Rxra_MA0494.2 16 bp overlap

Nr2F6 3 datasets

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

Motif DE_24h DE_24h-Nr2F6_MA0728.1 15 bp overlap

Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 316 bp overlap

ChIP H1 ENCFF770YBQ 413 bp overlap

ChIP H1 ENCFF833NJP 398 bp overlap

POU2F1::SOX2 2 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 368 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 139 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 369 bp overlap

PPARG 2 datasets

Motif DE_12h DE_12h-PPARG_MA0066.2 19 bp overlap

Motif DE_24h DE_24h-PPARG_MA0066.2 19 bp overlap

PROP1 2 datasets

Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap

Motif ES_0h ES_0h-PROP1_MA0715.1 11 bp overlap

Rarg 3 datasets

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

Motif DE_24h DE_24h-Rarg_MA0859.2 15 bp overlap

Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 287 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 240 bp overlap

SMARCA4 1 dataset

ChIP WA09 GSE105028.SMARCA4.WA09 53 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 410 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SPIB 2 datasets

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

Motif ES_0h ES_0h-SPIB_MA0081.3 13 bp overlap

SUPT5H 1 dataset

ChIP MOLT-4_SNS GSE89384.SUPT5H.MOLT-4_SNS 67 bp overlap

Motif DE_12h DE_12h-TBP_MA0108.3 7 bp overlap

Motif DE_24h DE_24h-TBP_MA0108.3 7 bp overlap

TEAD1 4 datasets

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

ChIP WTC11 ENCFF502QUV 384 bp overlap

TEAD2 3 datasets

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

Motif ES_0h ES_0h-TEAD2_MA1121.2 7 bp overlap

TEAD3 3 datasets

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif DE_12h DE_12h-TEAD3_MA0808.1 8 bp overlap

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 5 datasets

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

ChIP ESC S26-ESC-d0-TEAD4-exp1 353 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

THAP1 1 dataset

Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap

TRPS1 1 dataset

Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

VEZF1 3 datasets

Motif DE_12h DE_12h-VEZF1_MA1578.2 6 bp overlap

Motif DE_24h DE_24h-VEZF1_MA1578.2 6 bp overlap

Motif ES_0h ES_0h-VEZF1_MA1578.2 6 bp overlap

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZIC1 3 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif DE_24h DE_24h-ZIC1_MA0696.1 14 bp overlap

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZIC4 3 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap

Motif ES_0h ES_0h-ZIC4_MA0751.2 14 bp overlap

ZIC5 3 datasets

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap

Motif ES_0h ES_0h-ZIC5_MA1584.2 15 bp overlap

ZMAT4 1 dataset

ChIP WTC11 ENCFF608UXZ 241 bp overlap

ZNF148 1 dataset

Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap

ZNF157 2 datasets

Motif DE_12h DE_12h-ZNF157_MA2331.1 21 bp overlap

Motif DE_24h DE_24h-ZNF157_MA2331.1 21 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF449 1 dataset

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF675 3 datasets

Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap

Motif DE_24h DE_24h-ZNF675_MA1714.2 19 bp overlap

Motif ES_0h ES_0h-ZNF675_MA1714.2 19 bp overlap

ZNF684 2 datasets

Motif DE_12h DE_12h-ZNF684_MA1600.2 14 bp overlap

Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap

ZNF701 2 datasets

Motif DE_12h DE_12h-ZNF701_MA1987.2 17 bp overlap

Motif ES_0h ES_0h-ZNF701_MA1987.2 17 bp overlap

ZNF707 2 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Motif ES_0h ES_0h-ZNF707_MA1715.1 15 bp overlap

ZNF784 2 datasets

Motif DE_12h DE_12h-ZNF784_MA1717.2 8 bp overlap

Motif DE_24h DE_24h-ZNF784_MA1717.2 8 bp overlap