chr4 : 155,672,316 – 155,672,685
369 bp 81 TFs 1 linked gene
This 369 bp open chromatin element is linked to GUCY1A1 and is bound by 81 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GUCY1A1 5.4 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:155,667,316 – 155,677,685
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
81 transcription factors
Source
Cell type
AR 3 datasets
ChIP LNCaP-95_NT GSE125552.AR.LNCaP-95_NT 369 bp overlap
ChIP LNCaP-clone-FGC_DHT-DMSO GSE118247.AR.LNCaP-clone-FGC_DHT-DMSO 311 bp overlap
ChIP VCaP_shERG GSE110655.AR.VCaP_shERG 157 bp overlap
BAF155 2 datasets
ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 369 bp overlap
ChIP VCaP_shERG GSE110655.BAF155.VCaP_shERG 317 bp overlap
BNC2 3 datasets
ChIP SK-N-SH ENCFF174EMC 295 bp overlap
ChIP SK-N-SH ENCFF174EMC 87 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR754GYI.BNC2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 253 bp overlap
BRD4 1 dataset
ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 220 bp overlap
CDX2 1 dataset
ChIP Caco-2_DIFF GSE23436.CDX2.Caco-2_DIFF 147 bp overlap
CREB5 2 datasets
ChIP SK-N-SH ENCFF144PMI 229 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR758GOA.CREB5.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 301 bp overlap
CSDC2 2 datasets
ChIP SK-N-SH ENCFF868MXA 248 bp overlap
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR474KBG.CSDC2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 253 bp overlap
CTBP1 2 datasets
ChIP HEK293T ENCFF003PDY 198 bp overlap
ChIP HEK293T ENCSR237TFX.CTBP1.HEK293T 116 bp overlap
CTCF 1 dataset
Motif DE_60h DE_60h-CTCF_MA1929.2 31 bp overlap
DAXX 1 dataset
ChIP PC-3_DAXX GSE68647.DAXX.PC-3_DAXX 202 bp overlap
EBF3_P177L 1 dataset
ChIP SK-N-SH GSE90682.EBF3_P177L.SK-N-SH 127 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 258 bp overlap
EP300 1 dataset
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 132 bp overlap
ERG 1 dataset
ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 369 bp overlap
ESR1 8 datasets
ChIP MCF-7_E2 GSE60270.ESR1.MCF-7_E2 161 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 310 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 216 bp overlap
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 357 bp overlap
ChIP T-47D ENCSR000BKN.ESR1.T-47D 211 bp overlap
ChIP T-47D ENCSR000BJS.ESR1.T-47D 126 bp overlap
ChIP T-47D_D538G GSE148277.ESR1.T-47D_D538G 206 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 286 bp overlap
ESRRA 4 datasets
ChIP BT-474 GSE81651.ESRRA.BT-474 215 bp overlap
ChIP BT-474_AICAR GSE75876.ESRRA.BT-474_AICAR 173 bp overlap
ChIP BT-474_EGF GSE81651.ESRRA.BT-474_EGF 158 bp overlap
ChIP BT-474_HRG GSE81651.ESRRA.BT-474_HRG 330 bp overlap
ESRRG 2 datasets
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR023KKB.ESRRG.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 221 bp overlap
ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 369 bp overlap
FEZF1 2 datasets
ChIP HEK293 ENCFF528YED 254 bp overlap
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 152 bp overlap
FOXA1 5 datasets
ChIP MCF-7_TAMR_E2_TAM ERP000380.FOXA1.MCF-7_TAMR_E2_TAM 271 bp overlap
ChIP T-47D_shRNF2 GSE137579.FOXA1.T-47D_shRNF2 153 bp overlap
ChIP T-47D_shRNF2_45min GSE137579.FOXA1.T-47D_shRNF2_45min 181 bp overlap
ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 369 bp overlap
ChIP primary-prostate-cancer_P2_DSG GSE114737.FOXA1.primary-prostate-cancer_P2_DSG 369 bp overlap
FOXA2 3 datasets
ChIP Caco-2 GSE66218.FOXA2.Caco-2 129 bp overlap
ChIP DE DE-FOXA2-1 369 bp overlap
ChIP DE DE-FOXA2-2 360 bp overlap
FOXM1 1 dataset
ChIP HEK293 GSE60032.FOXM1.HEK293 155 bp overlap
GATA2 4 datasets
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP SK-N-SH ENCFF764OZD 310 bp overlap
ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 131 bp overlap
ChIP VCaP_JQ1 GSE125236.GATA2.VCaP_JQ1 140 bp overlap
GATA4 15 datasets
ChIP DE DE-GATA4-1 307 bp overlap
ChIP DE DE-GATA4-2 369 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP G296S GSE85628.GATA4.G296S 369 bp overlap
ChIP G296S_2 GSE85628.GATA4.G296S_2 369 bp overlap
ChIP G296S_4 GSE85628.GATA4.G296S_4 289 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 369 bp overlap
ChIP YCC-3 GSE51705.GATA4.YCC-3 224 bp overlap
ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 186 bp overlap
ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 188 bp overlap
ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 339 bp overlap
ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 182 bp overlap
ChIP foregut GSE117136.GATA4.foregut 276 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 301 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 271 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 18 datasets
ChIP AGS GSE51705.GATA6.AGS 227 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 183 bp overlap
ChIP DE DE-GATA6-1 328 bp overlap
ChIP DE DE-GATA6-2 369 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 353 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 357 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 304 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 313 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 369 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 353 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 254 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 319 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 225 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 320 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 338 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 261 bp overlap
GLIS3 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR507BWM.GLIS3.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 167 bp overlap
GRHL2 2 datasets
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 197 bp overlap
ChIP T-47D GSE99680.GRHL2.T-47D 197 bp overlap
Gata3 2 datasets
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 98 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 157 bp overlap
HOXB13 1 dataset
ChIP prostate_P19 GSE130408.HOXB13.prostate_P19 107 bp overlap
IKZF3 1 dataset
ChIP HEK293 ENCSR304AMN.IKZF3.HEK293 135 bp overlap
ISL1 2 datasets
ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 178 bp overlap
ChIP SK-N-SH ENCFF285GEQ 217 bp overlap
KLF3 1 dataset
ChIP HEK293 GSE69739.KLF3.HEK293 225 bp overlap
KLF5 1 dataset
ChIP HEK293_D418N GSE88976.KLF5.HEK293_D418N 204 bp overlap
KMT2A 1 dataset
ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 369 bp overlap
LIN54 1 dataset
Motif DE_60h DE_60h-LIN54_MA0619.2 7 bp overlap
MED1 2 datasets
ChIP G296S GSE85628.MED1.G296S 103 bp overlap
ChIP G296S_2 GSE85628.MED1.G296S_2 103 bp overlap
Mecom 1 dataset
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NKX2-1 1 dataset
ChIP NCI-H1819 GSE39998.NKX2-1.NCI-H1819 369 bp overlap
NKX2-4 1 dataset
Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap
NKX2-5 1 dataset
ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 141 bp overlap
NKX2-8 1 dataset
Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap
NR2C1 1 dataset
Motif DE_60h DE_60h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_60h DE_60h-NR2C2_MA1536.2 6 bp overlap
NR2F1 1 dataset
Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap
NUP98-HOXA9 1 dataset
ChIP HEK293-FT GSE62586.NUP98-HOXA9.HEK293-FT 365 bp overlap
Nr1H2 1 dataset
Motif DE_60h DE_60h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_60h DE_60h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_60h DE_60h-Nr1h3_MA2337.1 6 bp overlap
PHIP 1 dataset
ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 226 bp overlap
PHOX2B 1 dataset
ChIP SK-N-BE2-C GSE94822.PHOX2B.SK-N-BE2-C 160 bp overlap
PKNOX1 2 datasets
ChIP HEK293T ENCFF174WDB 228 bp overlap
ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 369 bp overlap
PRDM6 3 datasets
ChIP HEK293 ENCFF283AJL 369 bp overlap
ChIP HEK293 ENCFF283AJL 221 bp overlap
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 369 bp overlap
PSIP1 1 dataset
ChIP T-REx-293 GSE117155.PSIP1.T-REx-293 263 bp overlap
RARA 1 dataset
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 187 bp overlap
RCOR1 1 dataset
ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 172 bp overlap
Rarg 1 dataset
Motif DE_60h DE_60h-Rarg_MA0860.1 17 bp overlap
Rhox11 1 dataset
Motif DE_60h DE_60h-Rhox11_MA0629.2 9 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 323 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 258 bp overlap
SMAD3 2 datasets
ChIP HCC1954 GSE104760.SMAD3.HCC1954 256 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 273 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 218 bp overlap
SMARCC1 1 dataset
ChIP SYO-1_shRING1A-B GSE139053.SMARCC1.SYO-1_shRING1A-B 261 bp overlap
SNAI2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR106GVM.SNAI2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 109 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 189 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 262 bp overlap
SP5_Zebrafish 1 dataset
ChIP HEK293_Zebrafish_dDBD GSE121316.SP5_Zebrafish.HEK293_Zebrafish_dDBD 355 bp overlap
SP7 1 dataset
ChIP HEK293 ENCSR468IJT.SP7.HEK293 212 bp overlap
TBX5 3 datasets
ChIP G296S GSE85628.TBX5.G296S 369 bp overlap
ChIP G296S_2 GSE85628.TBX5.G296S_2 369 bp overlap
ChIP hiPSC GSE81585.TBX5.hiPSC 195 bp overlap
TCF4 1 dataset
ChIP SK-N-SH ENCFF270OWF 204 bp overlap
TCF7L2 3 datasets
ChIP HEK293 ENCFF513JQN 369 bp overlap
ChIP HEK293 ENCFF513JQN 250 bp overlap
ChIP HEK293 ENCSR000EUY.TCF7L2.HEK293 369 bp overlap
TEAD1 1 dataset
ChIP HEK293_siE1A GSE130135.TEAD1.HEK293_siE1A 115 bp overlap
TEAD4 5 datasets
ChIP BE2C GSE84389.TEAD4.BE2C 282 bp overlap
ChIP HEK293_siCtrl GSE130135.TEAD4.HEK293_siCtrl 369 bp overlap
ChIP SK-N-BE2 GSE84389.TEAD4.SK-N-BE2 282 bp overlap
ChIP SNU-216 GSE44416.TEAD4.SNU-216 199 bp overlap
ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 267 bp overlap
THRA 1 dataset
Motif DE_60h DE_60h-THRA_MA1969.2 18 bp overlap
THRB 1 dataset
Motif DE_60h DE_60h-THRB_MA1576.2 18 bp overlap
TRPS1 2 datasets
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 154 bp overlap
YY1AP1 2 datasets
ChIP T-47D_E2 GSE125594.YY1AP1.T-47D_E2 288 bp overlap
ChIP T-47D_Veh GSE125594.YY1AP1.T-47D_Veh 334 bp overlap
ZNF843 2 datasets
ChIP HEK293 ENCFF241QRH 151 bp overlap
ChIP HEK293 ENCSR502KPJ.ZNF843.HEK293 339 bp overlap
ZNF85 1 dataset
Motif DE_60h DE_60h-ZNF85_MA1720.2 12 bp overlap
ZXDB 1 dataset
ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 281 bp overlap
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