chr4 : 3,873,427 – 3,873,927

500 bp 50 TFs 2 linked genes

This 500 bp open chromatin element is linked to FAM86EP and ENSG00000290888 and is bound by 50 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
FAM86EP		82.0 kb	Distal	Multiome
ENSG00000290888		234.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

50 transcription factors

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 251 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 266 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 347 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 141 bp overlap

BRD4 2 datasets

ChIP SW480 GSE110473.BRD4.SW480 409 bp overlap

ChIP SW480_16h_TNF-a GSE110473.BRD4.SW480_16h_TNF-a 420 bp overlap

CTBP2 2 datasets

ChIP H1 ENCFF329MAX 458 bp overlap

ChIP WA01 ENCSR000EUO.CTBP2.WA01 251 bp overlap

ELF1 1 dataset

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 136 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 306 bp overlap

ESR1 3 datasets

ChIP Ishikawa_E2 GSE132426.ESR1.Ishikawa_E2 350 bp overlap

ChIP T-47D GSE148277.ESR1.T-47D 238 bp overlap

ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 426 bp overlap

EZH2 3 datasets

ChIP A-1847_CARM1-KO GSE95643.EZH2.A-1847_CARM1-KO 142 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 286 bp overlap

ChIP THP-1 GSE135024.EZH2.THP-1 449 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 210 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 126 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 223 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 197 bp overlap

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 172 bp overlap

HSF1 4 datasets

ChIP HCT-116_A10_43 GSE152144.HSF1.HCT-116_A10_43 79 bp overlap

ChIP HCT-116_A8_43 GSE152144.HSF1.HCT-116_A8_43 98 bp overlap

ChIP MCF-7_hyperthermia-15min GSE137558.HSF1.MCF-7_hyperthermia-15min 154 bp overlap

ChIP U2OS_HEAT_20 GSE60984.HSF1.U2OS_HEAT_20 128 bp overlap

JARID2 2 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 195 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 152 bp overlap

JUN 1 dataset

ChIP HUES-8 GSE109524.JUN.HUES-8 137 bp overlap

KLF1 3 datasets

ChIP HEK293 ENCFF159QSW 491 bp overlap

ChIP HEK293 ENCSR859BMR.KLF1.HEK293 500 bp overlap

ChIP HEK293 GSE76494.KLF1.HEK293 302 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 262 bp overlap

KLF4 1 dataset

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 112 bp overlap

KLF5 2 datasets

ChIP ESO-26 GSE132680.KLF5.ESO-26 322 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 167 bp overlap

KMT2B-D 1 dataset

ChIP SW480 GSE115985.KMT2B-D.SW480 447 bp overlap

MAX 1 dataset

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 233 bp overlap

MTF2 1 dataset

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 282 bp overlap

NFKB1 1 dataset

ChIP HEK293T GSE129618.NFKB1.HEK293T 174 bp overlap

NRF1 4 datasets

ChIP Hep-G2 ENCSR853ADA.NRF1.Hep-G2 189 bp overlap

ChIP HepG2 ENCFF694NVY 477 bp overlap

ChIP K-562 ENCSR837EYC.NRF1.K-562 118 bp overlap

ChIP K-562_Ab_R157-1-3D4 GSE97661.NRF1.K-562_Ab_R157-1-3D4 104 bp overlap

PCBP1 1 dataset

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 194 bp overlap

POU2F1 1 dataset

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 202 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 500 bp overlap

PRDM10 1 dataset

ChIP Hep-G2 ENCSR289PSX.PRDM10.Hep-G2 198 bp overlap

PTBP1 1 dataset

ChIP Hep-G2 ENCSR156APP.PTBP1.Hep-G2 170 bp overlap

RAD21 1 dataset

ChIP MCF-7_E2_SHCTCF ERP000209.RAD21.MCF-7_E2_SHCTCF 106 bp overlap

RELA 1 dataset

ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 243 bp overlap

REST 1 dataset

ChIP LNCaP GSE119385.REST.LNCaP 303 bp overlap

SMARCA4 3 datasets

ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 63 bp overlap

ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 357 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 176 bp overlap

SOX2 1 dataset

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 277 bp overlap

SOX6 1 dataset

ChIP Hep-G2 ENCSR766TSU.SOX6.Hep-G2 183 bp overlap

SP1 1 dataset

ChIP HEK293 GSE76494.SP1.HEK293 181 bp overlap

SP2 1 dataset

ChIP HEK293 GSE76494.SP2.HEK293 147 bp overlap

SP4 1 dataset

ChIP HEK293 GSE76494.SP4.HEK293 206 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 179 bp overlap

SS18-SSX 1 dataset

ChIP fibroblast_78aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_78aa-SSX-Tail 207 bp overlap

STAG1 1 dataset

ChIP MCF-7_E2_SHCTCF ERP000209.STAG1.MCF-7_E2_SHCTCF 111 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 500 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 297 bp overlap

TBP 1 dataset

ChIP K-562 GSE55306.TBP.K-562 64 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 314 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 87 bp overlap

TP53 2 datasets

ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 228 bp overlap

ChIP SW480_shp53_16h_TNF-a GSE115985.TP53.SW480_shp53_16h_TNF-a 332 bp overlap

ZMYM3 2 datasets

ChIP Hep-G2_Ab_JH39-2-2F10 GSE97661.ZMYM3.Hep-G2_Ab_JH39-2-2F10 59 bp overlap

ChIP HepG2 ENCFF408KTI 65 bp overlap

ZNF189 2 datasets

ChIP HEK293 ENCFF638TIB 454 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 404 bp overlap

ZNF48 1 dataset

ChIP HepG2 ENCFF362CDQ 439 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 500 bp overlap