chr2 : 181,665,217 – 181,665,739

522 bp 81 TFs 1 linked gene

This 522 bp open chromatin element is linked to CERKL and is bound by 81 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CERKL		8.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

81 transcription factors

ATF2 1 dataset

Motif DE_12h DE_12h-ATF2_MA1632.2 10 bp overlap

ATF4 1 dataset

Motif DE_12h DE_12h-ATF4_MA0833.3 10 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

CEBPG 1 dataset

Motif DE_12h DE_12h-CEBPG_MA1636.2 10 bp overlap

CREB1 1 dataset

Motif DE_12h DE_12h-CREB1_MA0018.5 8 bp overlap

CUX2 1 dataset

Motif DE_12h DE_12h-CUX2_MA0755.2 9 bp overlap

ELK1::HOXA1 1 dataset

Motif DE_12h DE_12h-ELK1HOXA1_MA1931.1 14 bp overlap

ERF::FOXI1 1 dataset

Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap

ESR1 1 dataset

ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FLI1::FOXI1 1 dataset

Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap

FOSB::JUN 1 dataset

Motif DE_12h DE_12h-FOSBJUN_MA1127.1 11 bp overlap

FOXJ2::ELF1 1 dataset

Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXP2 1 dataset

Motif DE_12h DE_12h-FOXP2_MA0593.2 9 bp overlap

GATA6 3 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 209 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 218 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 301 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

IKZF1 1 dataset

Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap

IRF3 1 dataset

Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap

Irf1 1 dataset

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

JUN 1 dataset

Motif DE_12h DE_12h-JUN_MA0488.2 10 bp overlap

JUN::JUNB 1 dataset

Motif DE_12h DE_12h-JUNJUNB_MA1133.2 11 bp overlap

JUND 1 dataset

Motif DE_12h DE_12h-JUND_MA0492.2 11 bp overlap

MXI1 1 dataset

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

MYB 1 dataset

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

MZF1 1 dataset

Motif DE_12h DE_12h-MZF1_MA0056.3 8 bp overlap

NFATC3 1 dataset

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

NFATC4 1 dataset

Motif DE_12h DE_12h-NFATC4_MA1525.3 9 bp overlap

NHLH2 1 dataset

Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap

NR2C2 1 dataset

Motif DE_12h DE_12h-NR2C2_MA0504.2 14 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Nfat5 1 dataset

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 1 dataset

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 1 dataset

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

POU1F1 1 dataset

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F2 1 dataset

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 2 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 336 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

SMAD2 2 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 293 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 522 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 522 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 273 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 448 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 513 bp overlap

SMARCA4 1 dataset

ChIP NGP_ARID1A-mut1 GSE134626.SMARCA4.NGP_ARID1A-mut1 162 bp overlap

SP5 1 dataset

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

SPIC 1 dataset

Motif DE_12h DE_12h-SPIC_MA0687.2 13 bp overlap

Six3 1 dataset

Motif DE_12h DE_12h-Six3_MA0631.2 11 bp overlap

Spi1 1 dataset

Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap

Stat2 2 datasets

Motif DE_12h DE_12h-Stat2_MA1623.2 10 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TCF7L1 1 dataset

Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap

TEAD1 1 dataset

Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

Yy1 1 dataset

Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap

ZBTB26 1 dataset

Motif DE_12h DE_12h-ZBTB26_MA1579.2 8 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZFP14 1 dataset

Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZKSCAN1 1 dataset

Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap

ZKSCAN5 1 dataset

Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF140 1 dataset

Motif DE_12h DE_12h-ZNF140_MA1589.2 19 bp overlap

ZNF354A 1 dataset

Motif DE_12h DE_12h-ZNF354A_MA1978.2 20 bp overlap

ZNF416 1 dataset

Motif DE_12h DE_12h-ZNF416_MA1979.2 10 bp overlap

ZNF418 1 dataset

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

ZNF528 1 dataset

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

ZNF547 1 dataset

Motif DE_12h DE_12h-ZNF547_MA2334.1 13 bp overlap

ZNF558 1 dataset

Motif DE_12h DE_12h-ZNF558_MA2335.1 29 bp overlap

ZNF574 1 dataset

Motif DE_12h DE_12h-ZNF574_MA1982.2 14 bp overlap

ZNF577 1 dataset

ChIP HEK293 ENCSR776MDR.ZNF577.HEK293 143 bp overlap

ZNF610 1 dataset

Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap

ZNF708 2 datasets

Motif DE_12h DE_12h-ZNF708_MA1730.2 9 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Zfp809 1 dataset

Motif DE_12h DE_12h-Zfp809_MA2125.1 9 bp overlap