chrX:103,766,973–103,767,614

chrX : 103,766,973 – 103,767,614

641 bp 82 TFs 6 linked genes

This 641 bp open chromatin element is linked to 6 target genes and is bound by 82 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PLP1		9.3 kb	Proximal	Proximity
MORF4L2		79.2 kb	Distal	Multiome
TMSB15B		152.0 kb	Distal	Multiome
TCEAL3		159.3 kb	Distal	Multiome
TCEAL4		181.7 kb	Distal	Multiome
ENSG00000234405		276.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

82 transcription factors

ARNT::HIF1A 2 datasets

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

Motif DE_24h DE_24h-ARNTHIF1A_MA0259.2 5 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BCL6B 3 datasets

Motif DE_12h DE_12h-BCL6B_MA0731.1 17 bp overlap

Motif DE_24h DE_24h-BCL6B_MA0731.1 17 bp overlap

Motif DE_36h DE_36h-BCL6B_MA0731.1 17 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 149 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 231 bp overlap

CEBPA 1 dataset

Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap

CEBPD 1 dataset

Motif DE_12h DE_12h-CEBPD_MA0836.3 8 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 306 bp overlap

CTCF 2 datasets

Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap

Motif DE_24h DE_24h-CTCF_MA1929.2 31 bp overlap

Motif DE_12h DE_12h-FOS_MA1951.2 13 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 324 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 319 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 604 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 429 bp overlap

GLIS3 2 datasets

Motif DE_12h DE_12h-GLIS3_MA0737.1 14 bp overlap

Motif DE_24h DE_24h-GLIS3_MA0737.1 14 bp overlap

HAND2 1 dataset

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

HIF1A 2 datasets

Motif DE_12h DE_12h-HIF1A_MA1106.2 6 bp overlap

Motif DE_24h DE_24h-HIF1A_MA1106.2 6 bp overlap

Motif DE_12h DE_12h-Irf1_MA0050.4 11 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 253 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 423 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 394 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 307 bp overlap

KLF1 4 datasets

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

Motif DE_24h DE_24h-KLF1_MA0493.3 8 bp overlap

KLF10 3 datasets

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

Motif DE_24h DE_24h-KLF10_MA1511.2 9 bp overlap

KLF14 3 datasets

Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

Motif DE_24h DE_24h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif DE_24h DE_24h-KLF16_MA0741.1 11 bp overlap

KLF17 2 datasets

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

Motif DE_24h DE_24h-KLF17_MA1514.2 14 bp overlap

KLF2 4 datasets

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

Motif DE_24h DE_24h-KLF2_MA1515.2 8 bp overlap

KLF4 4 datasets

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap

Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap

Motif DE_24h DE_24h-KLF4_MA0039.5 8 bp overlap

KLF5 4 datasets

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF5_MA0599.1 10 bp overlap

Motif DE_24h DE_24h-KLF9_MA1107.3 11 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MGA::EVX1 1 dataset

Motif DE_12h DE_12h-MGAEVX1_MA1960.2 11 bp overlap

MXI1 2 datasets

Motif DE_12h DE_12h-MXI1_MA1108.3 6 bp overlap

Motif DE_24h DE_24h-MXI1_MA1108.3 6 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 306 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 305 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFATC3 3 datasets

Motif DE_12h DE_12h-NFATC3_MA0625.3 6 bp overlap

Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap

Motif DE_36h DE_36h-NFATC3_MA0625.3 6 bp overlap

NFATC4 3 datasets

Motif DE_12h DE_12h-NFATC4_MA1525.3 9 bp overlap

Motif DE_24h DE_24h-NFATC4_MA1525.3 9 bp overlap

Motif DE_36h DE_36h-NFATC4_MA1525.3 9 bp overlap

NR2F1 2 datasets

Motif DE_12h DE_12h-NR2F1_MA0017.3 12 bp overlap

Motif DE_24h DE_24h-NR2F1_MA0017.3 12 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

Nfat5 3 datasets

Motif DE_12h DE_12h-Nfat5_MA0606.3 8 bp overlap

Motif DE_24h DE_24h-Nfat5_MA0606.3 8 bp overlap

Motif DE_36h DE_36h-Nfat5_MA0606.3 8 bp overlap

Nfatc1 3 datasets

Motif DE_12h DE_12h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap

Motif DE_36h DE_36h-Nfatc1_MA0624.3 6 bp overlap

Nfatc2 3 datasets

Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap

Motif DE_36h DE_36h-Nfatc2_MA0152.3 8 bp overlap

Nr2F6 2 datasets

Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap

Motif DE_24h DE_24h-Nr2F6_MA0728.1 15 bp overlap

PATZ1 3 datasets

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

Motif DE_24h DE_24h-PATZ1_MA1961.2 11 bp overlap

ChIP T-47D_R5020-A1 GSE126859.PGR.T-47D_R5020-A1 188 bp overlap

ChIP T-47D_R5020-MTVL GSE126859.PGR.T-47D_R5020-MTVL 167 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 400 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 437 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 271 bp overlap

Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap

RELA 2 datasets

ChIP CD4_Th1_BAY GSE62482.RELA.CD4_Th1_BAY 116 bp overlap

Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap

REST 24 datasets

ChIP GM23338 ENCFF024TCL 265 bp overlap

ChIP GM23338 ENCSR871KYB.REST.GM23338 195 bp overlap

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP HEK293 ENCFF073DOT 265 bp overlap

ChIP HEK293 ENCSR896UBV.REST.HEK293 361 bp overlap

ChIP HeLa-S3 ENCFF911DTC 245 bp overlap

ChIP HeLa-S3 ENCSR000BMN.REST.HeLa-S3 204 bp overlap

ChIP Hep-G2 ENCSR000BJL.REST.Hep-G2 132 bp overlap

ChIP Hep-G2 ENCSR000BOT.REST.Hep-G2 129 bp overlap

ChIP Ishikawa ENCFF456OHV 401 bp overlap

ChIP Ishikawa ENCSR000BUU.REST.Ishikawa 169 bp overlap

ChIP K-562 ENCSR000BMW.REST.K-562 134 bp overlap

ChIP MCF-7 ENCFF893RRD 345 bp overlap

ChIP MCF-7 ENCSR000BSP.REST.MCF-7 178 bp overlap

ChIP PANC-1 ENCSR000BPK.REST.PANC-1 246 bp overlap

ChIP PANC-1 ENCSR000BUP.REST.PANC-1 224 bp overlap

ChIP PANC-1 ENCSR000BJO.REST.PANC-1 190 bp overlap

ChIP PFSK-1 ENCFF845VHA 321 bp overlap

ChIP PFSK1 ENCSR000BOX.REST.PFSK1 212 bp overlap

ChIP Panc1 ENCFF518EEQ 481 bp overlap

ChIP Panc1 ENCFF518EEQ 283 bp overlap

ChIP SK-N-SH ENCFF635KBN 257 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 251 bp overlap

ChIP hiPSC_IA12 GSE106870.REST.hiPSC_IA12 193 bp overlap

RREB1 2 datasets

Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap

Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap

Rarg 2 datasets

Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap

Motif DE_24h DE_24h-Rarg_MA0859.2 15 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 503 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 348 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 87 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 337 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 353 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 641 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 347 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 182 bp overlap

SMARCC1 1 dataset

ChIP hiPSC GSE124903.SMARCC1.hiPSC 191 bp overlap

SOX10 2 datasets

Motif DE_12h DE_12h-SOX10_MA0442.3 6 bp overlap

Motif DE_24h DE_24h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 400 bp overlap

Motif DE_24h DE_24h-SP3_MA0746.3 11 bp overlap

Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap

Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 246 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 192 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 310 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 243 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 138 bp overlap

TBX19 1 dataset

Motif DE_12h DE_12h-TBX19_MA0804.2 17 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 484 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 330 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 262 bp overlap

TWIST1 1 dataset

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

Motif DE_12h DE_12h-Wt1_MA1627.2 10 bp overlap

Motif DE_24h DE_24h-Wt1_MA1627.2 10 bp overlap

ChIP NT2-D1 ENCSR000EXG.YY1.NT2-D1 97 bp overlap

Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap

ZFP42 1 dataset

Motif DE_12h DE_12h-ZFP42_MA1651.2 13 bp overlap

ZIC4 2 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap

ZIC5 2 datasets

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

Motif DE_24h DE_24h-ZIC5_MA1584.2 15 bp overlap

ZNF143 3 datasets

Motif DE_12h DE_12h-ZNF143_MA0088.2 16 bp overlap

Motif DE_24h DE_24h-ZNF143_MA0088.2 16 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 171 bp overlap

ZNF263 1 dataset

Motif DE_12h DE_12h-ZNF263_MA0528.3 7 bp overlap

ZNF341 3 datasets

Motif DE_12h DE_12h-ZNF341_MA1655.2 8 bp overlap

Motif DE_24h DE_24h-ZNF341_MA1655.2 8 bp overlap

Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap

ZNF418 3 datasets

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

Motif DE_12h DE_12h-ZNF418_MA1980.1 15 bp overlap

Motif DE_24h DE_24h-ZNF418_MA1980.1 15 bp overlap

ZNF449 5 datasets

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

Motif DE_12h DE_12h-ZNF449_MA1656.2 10 bp overlap

Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap

Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap

Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap

ZNF528 2 datasets

Motif DE_12h DE_12h-ZNF528_MA1597.1 17 bp overlap

Motif DE_24h DE_24h-ZNF528_MA1597.1 17 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF667 2 datasets

Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap

Motif DE_24h DE_24h-ZNF667_MA1984.2 11 bp overlap

ZNF707 3 datasets

Motif DE_12h DE_12h-ZNF707_MA1715.1 15 bp overlap

Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap

Motif DE_24h DE_24h-ZNF707_MA1715.1 15 bp overlap

ZNF784 3 datasets

Motif DE_12h DE_12h-ZNF784_MA1717.2 8 bp overlap

Motif DE_24h DE_24h-ZNF784_MA1717.2 8 bp overlap

Motif DE_36h DE_36h-ZNF784_MA1717.2 8 bp overlap

ZSCAN22 1 dataset

ChIP HEK293 GSE76494.ZSCAN22.HEK293 192 bp overlap