chr15 : 47,189,160 – 47,189,664

504 bp 91 TFs 1 linked gene

This 504 bp open chromatin element is linked to SEMA6D and is bound by 91 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
SEMA6D		5.1 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

91 transcription factors

BARHL1 1 dataset

Motif DE_12h DE_12h-BARHL1_MA0877.4 6 bp overlap

BARHL2 1 dataset

Motif DE_12h DE_12h-BARHL2_MA0635.2 6 bp overlap

BCOR 2 datasets

ChIP WA01 GSE104690.BCOR.WA01 230 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 210 bp overlap

CHD7 1 dataset

ChIP H1 ENCFF126NLU 504 bp overlap

Crx 1 dataset

Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap

DMRTC2 1 dataset

Motif DE_12h DE_12h-DMRTC2_MA1479.2 11 bp overlap

DPRX 1 dataset

Motif DE_12h DE_12h-DPRX_MA1480.2 9 bp overlap

EOMES 1 dataset

Motif DE_12h DE_12h-EOMES_MA0800.2 9 bp overlap

EP300 3 datasets

ChIP H1 ENCFF927IYK 297 bp overlap

ChIP WA01 ENCSR000BKK.EP300.WA01 171 bp overlap

ChIP neural cell ENCFF442QNK 358 bp overlap

FERD3L 1 dataset

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

FIGLA 1 dataset

Motif DE_12h DE_12h-FIGLA_MA0820.2 6 bp overlap

FOXA1 2 datasets

ChIP LNCaP_L388M_shFOXA1 GSE128883.FOXA1.LNCaP_L388M_shFOXA1 165 bp overlap

ChIP T-47D_JC4745 GSE126004.FOXA1.T-47D_JC4745 182 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 269 bp overlap

ChIP DE DE-FOXA2-2 239 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 205 bp overlap

FOXD2 2 datasets

Motif DE_12h DE_12h-FOXD2_MA0847.4 11 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 387 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 229 bp overlap

GSC 1 dataset

Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap

HMBOX1 1 dataset

Motif DE_12h DE_12h-HMBOX1_MA0895.2 7 bp overlap

IRF2 1 dataset

ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 155 bp overlap

ISL2 1 dataset

Motif DE_12h DE_12h-ISL2_MA0914.2 6 bp overlap

KLF4 1 dataset

ChIP WA09 GSE105028.KLF4.WA09 275 bp overlap

MEIS1 2 datasets

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MEIS2 1 dataset

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

MEIS3 1 dataset

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

MGA 1 dataset

Motif DE_12h DE_12h-MGA_MA0801.1 8 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 294 bp overlap

MYBL1 1 dataset

Motif DE_12h DE_12h-MYBL1_MA0776.1 12 bp overlap

MYOD1 1 dataset

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 223 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 280 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 504 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 430 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 316 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 504 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 504 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 504 bp overlap

ChIP hESC GSE20650.NANOG.hESC 265 bp overlap

ChIP hESC GSE18292.NANOG.hESC 167 bp overlap

NEUROD1 1 dataset

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 155 bp overlap

NIPBL 2 datasets

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 228 bp overlap

ChIP hESC_activin GSE64758.NIPBL.hESC_activin 221 bp overlap

ONECUT1 1 dataset

ChIP H9 ERP004206.ONECUT1.H9 219 bp overlap

OSR1 1 dataset

Motif DE_12h DE_12h-OSR1_MA1542.2 8 bp overlap

OTX1 1 dataset

Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap

OTX2 2 datasets

Motif DE_12h DE_12h-OTX2_MA0712.3 7 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

PAX3 1 dataset

Motif DE_12h DE_12h-PAX3_MA1546.2 14 bp overlap

PBX1 1 dataset

Motif DE_12h DE_12h-PBX1_MA0070.2 9 bp overlap

PBX3 1 dataset

Motif DE_12h DE_12h-PBX3_MA1114.2 11 bp overlap

PITX1 1 dataset

Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap

PITX2 1 dataset

Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap

PITX3 1 dataset

Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap

PKNOX1 1 dataset

Motif DE_12h DE_12h-PKNOX1_MA0782.3 10 bp overlap

PKNOX2 1 dataset

Motif DE_12h DE_12h-PKNOX2_MA0783.1 12 bp overlap

POU2F1 1 dataset

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F3 1 dataset

Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

POU3F4 1 dataset

Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap

POU5F1 11 datasets

Motif DE_12h DE_12h-POU5F1_MA1115.2 7 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 414 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 448 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 250 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 224 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 176 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 411 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 486 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 166 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 146 bp overlap

POU5F1B 1 dataset

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

PRDM14 1 dataset

ChIP hESC GSE138674.PRDM14.hESC 206 bp overlap

PRDM6 1 dataset

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 266 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1620.2 8 bp overlap

RBPJ 1 dataset

Motif DE_12h DE_12h-RBPJ_MA1116.2 6 bp overlap

RELA 1 dataset

ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 120 bp overlap

RFX2 1 dataset

Motif DE_12h DE_12h-RFX2_MA0600.3 14 bp overlap

RFX5 1 dataset

Motif DE_12h DE_12h-RFX5_MA0510.3 14 bp overlap

RHOXF1 1 dataset

Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap

RNF2 3 datasets

ChIP HUES-64 GSE104059.RNF2.HUES-64 236 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 503 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 237 bp overlap

RUNX1 1 dataset

ChIP 697 GSE138031.RUNX1.697 233 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 301 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 361 bp overlap

SMAD2_3 2 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 309 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 289 bp overlap

SMARCA4 5 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 504 bp overlap

ChIP WA09 GSE105028.SMARCA4.WA09 245 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 243 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 332 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 290 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 220 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 280 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 303 bp overlap

SNAI2 1 dataset

Motif DE_12h DE_12h-SNAI2_MA0745.3 8 bp overlap

SNAI3 1 dataset

Motif DE_12h DE_12h-SNAI3_MA1559.2 9 bp overlap

SOX2 2 datasets

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 199 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 334 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 155 bp overlap

Stat5a::Stat5b 1 dataset

Motif DE_12h DE_12h-Stat5aStat5b_MA0519.2 9 bp overlap

TBR1 1 dataset

Motif DE_12h DE_12h-TBR1_MA0802.2 9 bp overlap

TBX1 1 dataset

Motif DE_12h DE_12h-TBX1_MA0805.1 8 bp overlap

TBX15 1 dataset

Motif DE_12h DE_12h-TBX15_MA0803.1 8 bp overlap

TBX18 1 dataset

Motif DE_12h DE_12h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_12h DE_12h-TBX2_MA0688.2 9 bp overlap

TBX21 1 dataset

Motif DE_12h DE_12h-TBX21_MA0690.3 10 bp overlap

TBX3 1 dataset

Motif DE_12h DE_12h-TBX3_MA1566.3 9 bp overlap

TBX4 1 dataset

Motif DE_12h DE_12h-TBX4_MA0806.1 8 bp overlap

TBX5 1 dataset

Motif DE_12h DE_12h-TBX5_MA0807.1 8 bp overlap

TGIF1 1 dataset

Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap

TGIF2 1 dataset

Motif DE_12h DE_12h-TGIF2_MA0797.1 12 bp overlap

TGIF2LX 1 dataset

Motif DE_12h DE_12h-TGIF2LX_MA1571.1 12 bp overlap

TGIF2LY 1 dataset

Motif DE_12h DE_12h-TGIF2LY_MA1572.1 12 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 382 bp overlap

Tbx6 1 dataset

Motif DE_12h DE_12h-Tbx6_MA1567.3 9 bp overlap

ZBTB32 1 dataset

Motif DE_12h DE_12h-ZBTB32_MA1580.1 10 bp overlap

ZEB1 1 dataset

Motif DE_12h DE_12h-ZEB1_MA0103.4 6 bp overlap

ZNF449 1 dataset

ChIP HEK293 ENCSR738SLS.ZNF449.HEK293 105 bp overlap

ZNF547 1 dataset

Motif DE_12h DE_12h-ZNF547_MA2334.1 13 bp overlap

ZNF75A 1 dataset

Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap