chr13 : 79,859,849 – 79,860,792
943 bp 100 TFs 1 linked gene
This 943 bp open chromatin element is linked to SPRY2 and is bound by 100 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SPRY2 480.7 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr13:79,854,849 – 79,865,792
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
100 transcription factors
Source
Cell type
Arid5a 1 dataset
Motif DE_12h DE_12h-Arid5a_MA0602.2 8 bp overlap
CDK9 1 dataset
ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 197 bp overlap
CDX1 2 datasets
Motif DE_12h DE_12h-CDX1_MA0878.3 10 bp overlap
Motif DE_48h DE_48h-CDX1_MA0878.3 10 bp overlap
CDX2 3 datasets
Motif DE_12h DE_12h-CDX2_MA0465.3 8 bp overlap
Motif DE_48h DE_48h-CDX2_MA0465.3 8 bp overlap
ChIP LS180_125 GSE31939.CDX2.LS180_125 148 bp overlap
CDX4 2 datasets
Motif DE_12h DE_12h-CDX4_MA1473.2 9 bp overlap
Motif DE_48h DE_48h-CDX4_MA1473.2 9 bp overlap
CEBPA 1 dataset
Motif DE_12h DE_12h-CEBPA_MA0102.5 10 bp overlap
EHF 5 datasets
Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap
Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap
Motif DE_12h DE_12h-EHF_MA0598.4 9 bp overlap
Motif DE_24h DE_24h-EHF_MA0598.4 9 bp overlap
Motif DE_48h DE_48h-EHF_MA0598.4 9 bp overlap
ELF1 3 datasets
Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap
Motif DE_12h DE_12h-ELF1_MA0473.4 9 bp overlap
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
ELF2 3 datasets
Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap
Motif DE_12h DE_12h-ELF2_MA1483.3 10 bp overlap
Motif DE_48h DE_48h-ELF2_MA1483.3 10 bp overlap
ELF3 5 datasets
Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap
Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap
Motif DE_12h DE_12h-ELF3_MA0640.3 9 bp overlap
Motif DE_24h DE_24h-ELF3_MA0640.3 9 bp overlap
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
ELF4 1 dataset
Motif DE_12h DE_12h-ELF4_MA0641.1 12 bp overlap
ERF 2 datasets
Motif DE_12h DE_12h-ERF_MA0760.2 9 bp overlap
Motif DE_48h DE_48h-ERF_MA0760.2 9 bp overlap
ERF::FOXI1 3 datasets
Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_12h DE_12h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap
ERF::FOXO1 4 datasets
Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_12h DE_12h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_24h DE_24h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
ERF::HOXB13 1 dataset
Motif DE_12h DE_12h-ERFHOXB13_MA1937.2 13 bp overlap
ETS1 2 datasets
Motif DE_12h DE_12h-ETS1_MA0098.4 9 bp overlap
Motif DE_48h DE_48h-ETS1_MA0098.4 9 bp overlap
ETV1 3 datasets
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
Motif DE_12h DE_12h-ETV1_MA0761.3 9 bp overlap
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
ETV2 2 datasets
Motif DE_12h DE_12h-ETV2_MA0762.2 9 bp overlap
Motif DE_48h DE_48h-ETV2_MA0762.2 9 bp overlap
ETV2::DRGX 1 dataset
Motif DE_12h DE_12h-ETV2DRGX_MA1940.2 12 bp overlap
ETV2::FOXI1 3 datasets
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_12h DE_12h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV2::HOXB13 1 dataset
Motif DE_12h DE_12h-ETV2HOXB13_MA1943.2 13 bp overlap
ETV5::DRGX 3 datasets
Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_12h DE_12h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_12h DE_12h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_24h DE_24h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 2 datasets
Motif DE_12h DE_12h-Elf5_MA0136.4 8 bp overlap
Motif DE_24h DE_24h-Elf5_MA0136.4 8 bp overlap
Erg 4 datasets
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
Motif DE_12h DE_12h-Erg_MA0474.4 10 bp overlap
Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FLI1 2 datasets
Motif DE_12h DE_12h-FLI1_MA0475.3 9 bp overlap
Motif DE_48h DE_48h-FLI1_MA0475.3 9 bp overlap
FLI1::DRGX 3 datasets
Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_12h DE_12h-FLI1DRGX_MA1949.2 14 bp overlap
Motif DE_48h DE_48h-FLI1DRGX_MA1949.2 14 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_12h DE_12h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 346 bp overlap
ChIP DE DE-FOXA2-2 264 bp overlap
FOXB1 1 dataset
Motif DE_12h DE_12h-FOXB1_MA0845.1 11 bp overlap
FOXD3 2 datasets
Motif DE_12h DE_12h-FOXD3_MA0041.3 14 bp overlap
Motif DE_48h DE_48h-FOXD3_MA0041.3 14 bp overlap
FOXJ2::ELF1 3 datasets
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_12h DE_12h-FOXJ2ELF1_MA1952.2 11 bp overlap
Motif DE_48h DE_48h-FOXJ2ELF1_MA1952.2 11 bp overlap
FOXO1::ELF1 2 datasets
Motif DE_12h DE_12h-FOXO1ELF1_MA1953.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELF1_MA1953.2 13 bp overlap
FOXO1::ELK1 2 datasets
Motif DE_12h DE_12h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::FLI1 2 datasets
Motif DE_12h DE_12h-FOXO1FLI1_MA1956.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1FLI1_MA1956.2 13 bp overlap
GABPA 4 datasets
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
Motif DE_12h DE_12h-GABPA_MA0062.4 10 bp overlap
Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
GATA3 1 dataset
ChIP Jurkat GSE76181.GATA3.Jurkat 232 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 430 bp overlap
ChIP DE DE-GATA4-2 624 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 460 bp overlap
ChIP DE DE-GATA6-2 599 bp overlap
Motif DE_12h DE_12h-GATA6_MA1104.3 8 bp overlap
Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 635 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 760 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 717 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 452 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 756 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 681 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 322 bp overlap
Gata3 2 datasets
Motif DE_12h DE_12h-Gata3_MA0037.5 8 bp overlap
Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap
HAND2 2 datasets
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif DE_48h DE_48h-HAND2_MA1638.2 6 bp overlap
HOXB13 2 datasets
Motif DE_12h DE_12h-HOXB13_MA0901.3 9 bp overlap
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
Hand1 3 datasets
Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap
Motif DE_24h DE_24h-Hand1_MA2123.1 9 bp overlap
Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap
Hmga1 1 dataset
Motif DE_12h DE_12h-Hmga1_MA2124.1 8 bp overlap
Hnf1A 2 datasets
Motif DE_12h DE_12h-Hnf1A_MA1991.2 10 bp overlap
Motif DE_24h DE_24h-Hnf1A_MA1991.2 10 bp overlap
Hoxa13 2 datasets
Motif DE_12h DE_12h-Hoxa13_MA0650.4 8 bp overlap
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
Hoxd13 2 datasets
Motif DE_12h DE_12h-Hoxd13_MA0909.4 7 bp overlap
Motif DE_48h DE_48h-Hoxd13_MA0909.4 7 bp overlap
IKZF1 2 datasets
Motif DE_12h DE_12h-IKZF1_MA1508.2 8 bp overlap
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Isl1 3 datasets
Motif DE_12h DE_12h-Isl1_MA1608.2 7 bp overlap
Motif DE_24h DE_24h-Isl1_MA1608.2 7 bp overlap
Motif DE_48h DE_48h-Isl1_MA1608.2 7 bp overlap
JUN 4 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 554 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 561 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 447 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 493 bp overlap
LIN54 1 dataset
Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap
LMO1 1 dataset
ChIP Jurkat GSE94391.LMO1.Jurkat 191 bp overlap
Lhx3 1 dataset
Motif DE_12h DE_12h-Lhx3_MA0135.2 12 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
MYB 1 dataset
ChIP Jurkat GSE59657.MYB.Jurkat 350 bp overlap
Mecom 2 datasets
Motif DE_12h DE_12h-Mecom_MA0029.2 11 bp overlap
Motif DE_24h DE_24h-Mecom_MA0029.2 11 bp overlap
NANOG 2 datasets
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 342 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 203 bp overlap
NEUROD1 2 datasets
Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
Neurod2 2 datasets
Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Nfatc2 2 datasets
Motif DE_12h DE_12h-Nfatc2_MA0152.3 8 bp overlap
Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap
OLIG2 1 dataset
Motif DE_12h DE_12h-OLIG2_MA0678.1 10 bp overlap
OLIG3 1 dataset
Motif DE_12h DE_12h-OLIG3_MA0827.1 10 bp overlap
PAX6 1 dataset
Motif DE_12h DE_12h-PAX6_MA0069.1 14 bp overlap
PHOX2B 1 dataset
Motif DE_12h DE_12h-PHOX2B_MA0681.3 12 bp overlap
POU1F1 1 dataset
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
POU2F2 1 dataset
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
POU3F1 1 dataset
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
POU3F2 1 dataset
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
POU3F3 1 dataset
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
POU5F1B 1 dataset
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
PPARA::RXRA 1 dataset
Motif DE_12h DE_12h-PPARARXRA_MA1148.2 17 bp overlap
PROP1 1 dataset
Motif DE_12h DE_12h-PROP1_MA0715.1 11 bp overlap
Prdm14 2 datasets
Motif DE_12h DE_12h-Prdm14_MA1998.2 8 bp overlap
Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap
Ptf1A 2 datasets
Motif DE_12h DE_12h-Ptf1A_MA1618.2 9 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1618.2 9 bp overlap
RREB1 1 dataset
Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap
RUNX1 2 datasets
ChIP Jurkat GSE68976.RUNX1.Jurkat 226 bp overlap
ChIP Jurkat GSE76181.RUNX1.Jurkat 211 bp overlap
SMAD2 1 dataset
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 346 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 790 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 781 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 773 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 766 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 763 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 743 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 737 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 573 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 254 bp overlap
SP5 3 datasets
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
Motif DE_36h DE_36h-SP5_MA1965.2 6 bp overlap
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
SPIB 2 datasets
Motif DE_12h DE_12h-SPIB_MA0081.3 13 bp overlap
Motif DE_24h DE_24h-SPIB_MA0081.3 13 bp overlap
SREBF2 2 datasets
Motif DE_12h DE_12h-SREBF2_MA0596.1 10 bp overlap
Motif DE_24h DE_24h-SREBF2_MA0596.1 10 bp overlap
SRF 1 dataset
Motif DE_12h DE_12h-SRF_MA0083.3 16 bp overlap
Sox6 2 datasets
Motif DE_12h DE_12h-Sox6_MA0515.1 10 bp overlap
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Spi1 2 datasets
Motif DE_12h DE_12h-Spi1_MA0080.7 13 bp overlap
Motif DE_24h DE_24h-Spi1_MA0080.7 13 bp overlap
Stat6 2 datasets
Motif DE_12h DE_12h-Stat6_MA0520.2 10 bp overlap
Motif DE_24h DE_24h-Stat6_MA0520.2 10 bp overlap
TAL1 1 dataset
ChIP MOLT-3 GSE59657.TAL1.MOLT-3 192 bp overlap
TCF7L1 2 datasets
Motif DE_12h DE_12h-TCF7L1_MA1421.1 12 bp overlap
Motif DE_24h DE_24h-TCF7L1_MA1421.1 12 bp overlap
TCF7L2 4 datasets
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_12h DE_12h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_24h DE_24h-TCF7L2_MA0523.2 9 bp overlap
Motif DE_24h DE_24h-TCF7L2_MA0523.2 9 bp overlap
TRPS1 2 datasets
Motif DE_12h DE_12h-TRPS1_MA1970.2 8 bp overlap
Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap
ZBTB18 2 datasets
Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
ZFP14 3 datasets
Motif DE_12h DE_12h-ZFP14_MA1972.1 15 bp overlap
Motif DE_36h DE_36h-ZFP14_MA1972.1 15 bp overlap
Motif DE_48h DE_48h-ZFP14_MA1972.1 15 bp overlap
ZKSCAN5 1 dataset
Motif DE_12h DE_12h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF136 1 dataset
Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap
ZNF175 2 datasets
Motif DE_12h DE_12h-ZNF175_MA2332.1 9 bp overlap
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
ZNF675 2 datasets
Motif DE_12h DE_12h-ZNF675_MA1714.2 19 bp overlap
Motif DE_24h DE_24h-ZNF675_MA1714.2 19 bp overlap
ZNF75A 1 dataset
Motif DE_12h DE_12h-ZNF75A_MA2097.1 12 bp overlap
ZSCAN16 2 datasets
Motif DE_12h DE_12h-ZSCAN16_MA2100.1 18 bp overlap
Motif DE_48h DE_48h-ZSCAN16_MA2100.1 18 bp overlap
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