chr11:63,503,095–63,503,560

chr11 : 63,503,095 – 63,503,560

465 bp 72 TFs 6 linked genes

This 465 bp open chromatin element is linked to 6 target genes and is bound by 72 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LGALS12		2.8 kb	Proximal	Proximity
PLAAT5		12.1 kb	Distal	Multiome
PLAAT3		111.1 kb	Distal	Multiome
ATL3		168.4 kb	Distal	Multiome
RTN3		178.2 kb	Distal	Multiome
ZFTA		265.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

72 transcription factors

ARID1B 1 dataset

ChIP K-562 ENCSR822CCM.ARID1B.K-562 279 bp overlap

BCL11A 1 dataset

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 54 bp overlap

BRD3 4 datasets

ChIP H-1_DE GSE126661.BRD3.H-1_DE 70 bp overlap

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 120 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 137 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 185 bp overlap

BRD4 5 datasets

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 66 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 92 bp overlap

ChIP MV4-11-B_DMSO GSE101821.BRD4.MV4-11-B_DMSO 241 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 155 bp overlap

ChIP OCI-AML3 GSE104745.BRD4.OCI-AML3 149 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 278 bp overlap

ChIP K562 ENCFF673OEZ 116 bp overlap

Motif DE_48h DE_48h-CTCF_MA0139.2 15 bp overlap

CUX1 3 datasets

Motif DE_48h DE_48h-CUX1_MA0754.3 9 bp overlap

ChIP K-562 ENCSR000EFO.CUX1.K-562 157 bp overlap

ChIP K562 ENCFF057AIX 345 bp overlap

Motif DE_48h DE_48h-CUX2_MA0755.2 9 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 111 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 160 bp overlap

EP300 1 dataset

ChIP tibial nerve ENCFF346AYA 137 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 392 bp overlap

ChIP DE DE-FOXA2-2 425 bp overlap

GABPA 1 dataset

ChIP HL-60 ENCFF515BEZ 65 bp overlap

GATA1 1 dataset

ChIP K-562 GSE107726.GATA1.K-562 322 bp overlap

GATA2 1 dataset

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 465 bp overlap

ChIP DE DE-GATA4-2 465 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 277 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 385 bp overlap

GATA5 1 dataset

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP DE DE-GATA6-1 465 bp overlap

ChIP DE DE-GATA6-2 465 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 460 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 465 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 465 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 465 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 465 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 465 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 465 bp overlap

ChIP foregut GSE117136.GATA6.foregut 346 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 334 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 364 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 417 bp overlap

Gata3 2 datasets

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

HDAC8 1 dataset

ChIP K-562 ENCSR835TCD.HDAC8.K-562 465 bp overlap

HOXB4 2 datasets

Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap

Motif DE_48h DE_48h-HOXB4_MA1499.2 6 bp overlap

HOXC4 2 datasets

Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap

Motif DE_48h DE_48h-HOXC4_MA1504.2 6 bp overlap

HOXD4 2 datasets

Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap

Motif DE_48h DE_48h-HOXD4_MA1507.2 6 bp overlap

Hand1 1 dataset

Motif DE_48h DE_48h-Hand1_MA2123.1 9 bp overlap

JMJD1C 1 dataset

ChIP NB4 GSE63484.JMJD1C.NB4 101 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 437 bp overlap

KDM1A 1 dataset

ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 115 bp overlap

LDB1 3 datasets

ChIP K-562 GSE142227.LDB1.K-562 311 bp overlap

ChIP Kasumi-1_ctrl GSE121280.LDB1.Kasumi-1_ctrl 54 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 115 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 430 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 232 bp overlap

NFYB 2 datasets

ChIP K-562 ENCSR000EGQ.NFYB.K-562 283 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 206 bp overlap

NKX6-3 2 datasets

Motif DE_24h DE_24h-NKX6-3_MA1530.2 8 bp overlap

Motif DE_48h DE_48h-NKX6-3_MA1530.2 8 bp overlap

NR2F1 1 dataset

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 271 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 140 bp overlap

NR2F6 1 dataset

ChIP K562 ENCFF674RQA 390 bp overlap

Nfat5 1 dataset

Motif DE_48h DE_48h-Nfat5_MA0606.3 8 bp overlap

ONECUT1 3 datasets

Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap

ChIP H9 ERP004206.ONECUT1.H9 194 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 465 bp overlap

ONECUT2 2 datasets

ChIP AGS_Overexpression GSE113045.ONECUT2.AGS_Overexpression 187 bp overlap

Motif DE_48h DE_48h-ONECUT2_MA0756.3 8 bp overlap

POLR2A 2 datasets

ChIP NB4 ENCFF780KAX 161 bp overlap

ChIP spleen ENCFF044PYR 102 bp overlap

POU1F1 3 datasets

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap

Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap

POU2F1 3 datasets

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

Motif DE_48h DE_48h-POU2F1_MA0785.2 9 bp overlap

Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap

POU2F2 3 datasets

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap

Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap

POU3F1 3 datasets

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif DE_48h DE_48h-POU3F1_MA0786.2 10 bp overlap

Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap

POU3F2 3 datasets

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap

Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap

POU3F3 3 datasets

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap

Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap

POU5F1 1 dataset

ChIP DE_D1 DED1-OCT4_Batch_II 359 bp overlap

POU5F1B 3 datasets

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_48h DE_48h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_60h DE_60h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 297 bp overlap

POU6F1 2 datasets

Motif DE_24h DE_24h-POU6F1_MA1549.2 7 bp overlap

Motif DE_48h DE_48h-POU6F1_MA1549.2 7 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 150 bp overlap

Prdm14 1 dataset

Motif DE_48h DE_48h-Prdm14_MA1998.2 8 bp overlap

RBM39 2 datasets

ChIP K-562 ENCSR764OXF.RBM39.K-562 113 bp overlap

ChIP K-562 GSE120104.RBM39.K-562 102 bp overlap

RUNX1 5 datasets

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 65 bp overlap

ChIP HL-60 GSE107553.RUNX1.HL-60 96 bp overlap

ChIP Kasumi-1 GSE45738.RUNX1.Kasumi-1 158 bp overlap

ChIP Kasumi-1 GSE62847.RUNX1.Kasumi-1 117 bp overlap

ChIP NB4 GSE81992.RUNX1.NB4 115 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 153 bp overlap

ChIP HL-60 GSE107553.SKI.HL-60 85 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 364 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 465 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 465 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 465 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 465 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 465 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 465 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 465 bp overlap

SMARCA4 1 dataset

ChIP hiPSC GSE124903.SMARCA4.hiPSC 164 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 168 bp overlap

SOX15 1 dataset

Motif DE_48h DE_48h-SOX15_MA1152.2 7 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 406 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 465 bp overlap

SPI1 2 datasets

ChIP U-937 GSE128834.SPI1.U-937 54 bp overlap

ChIP primary-monocyte_18h_donorO GSE128834.SPI1.primary-monocyte_18h_donorO 82 bp overlap

SREBP2 2 datasets

ChIP monocyte GSE129202.SREBP2.monocyte 72 bp overlap

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 144 bp overlap

Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TAL1 2 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 102 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 189 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 126 bp overlap

TRPS1 2 datasets

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

ZNF639 1 dataset

ChIP K562 ENCFF271FQR 219 bp overlap

ZNF652 1 dataset

Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap

ZNF740 1 dataset

ChIP K562 ENCFF913GVQ 303 bp overlap