chr8 : 11,288,724 – 11,289,361

637 bp 70 TFs 2 linked genes

This 637 bp open chromatin element is linked to ENSG00000280273 and MTMR9 and is bound by 70 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000280273		3.7 kb	Proximal	Proximity
MTMR9		3.9 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

70 transcription factors

ATF2 1 dataset

ChIP HEK293 ENCSR217HTK.ATF2.HEK293 53 bp overlap

ATF3 3 datasets

ChIP K-562 ENCSR632DCH.ATF3.K-562 101 bp overlap

ChIP K-562 ENCSR028UIU.ATF3.K-562 78 bp overlap

ChIP K562 ENCFF604FPV 58 bp overlap

BRD1 1 dataset

ChIP HUES-64 GSE104059.BRD1.HUES-64 94 bp overlap

Cebpa 3 datasets

ChIP BLaER1 ENCFF093OYK 299 bp overlap

ChIP BLaER1 ENCFF274GAT 276 bp overlap

ChIP BLaER1 ENCFF844FIP 284 bp overlap

EOMES 1 dataset

Motif DE_24h DE_24h-EOMES_MA0800.2 9 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_24h DE_24h-ETV5HOXA2_MA1948.2 12 bp overlap

FOS 1 dataset

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 54 bp overlap

FOSL1 1 dataset

ChIP K562 ENCFF455MKD 183 bp overlap

GATA6 2 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 263 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 74 bp overlap

GLIS1 2 datasets

ChIP HEK293 ENCFF299RSE 457 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 464 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 250 bp overlap

HOXA3 1 dataset

Motif DE_24h DE_24h-HOXA3_MA2119.1 7 bp overlap

HOXA4 1 dataset

Motif DE_24h DE_24h-HOXA4_MA1496.2 7 bp overlap

HOXB4 1 dataset

Motif DE_24h DE_24h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_24h DE_24h-HOXC4_MA1504.2 6 bp overlap

HOXD12::ELK1 1 dataset

Motif DE_24h DE_24h-HOXD12ELK1_MA1958.2 13 bp overlap

HOXD4 1 dataset

Motif DE_24h DE_24h-HOXD4_MA1507.2 6 bp overlap

IRF1 1 dataset

ChIP K-562 ENCSR854MCV.IRF1.K-562 242 bp overlap

JUN 4 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 592 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 494 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 388 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 275 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 245 bp overlap

KLF8 2 datasets

ChIP HEK293 ENCFF929IAJ 125 bp overlap

ChIP HEK293 ENCSR635NOQ.KLF8.HEK293 155 bp overlap

MAFG 1 dataset

ChIP K-562 ENCSR818DQV.MAFG.K-562 85 bp overlap

MLLT1 1 dataset

ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 356 bp overlap

NANOG 2 datasets

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 285 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 146 bp overlap

NKX6-1 1 dataset

Motif DE_24h DE_24h-NKX6-1_MA0674.2 7 bp overlap

NKX6-3 1 dataset

Motif DE_24h DE_24h-NKX6-3_MA1530.2 8 bp overlap

NR3C1 1 dataset

ChIP T47D-A1-2_Dex GSE112491.NR3C1.T47D-A1-2_Dex 165 bp overlap

Nr2F6 1 dataset

Motif DE_24h DE_24h-Nr2F6_MA0728.1 15 bp overlap

Nr2e1 1 dataset

Motif DE_24h DE_24h-Nr2e1_MA0676.1 9 bp overlap

OSR2 1 dataset

ChIP HEK293 ENCSR324LTM.OSR2.HEK293 224 bp overlap

PGR 3 datasets

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 77 bp overlap

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 57 bp overlap

ChIP T-47D_R5020-MTVL GSE126859.PGR.T-47D_R5020-MTVL 98 bp overlap

POU4F1 1 dataset

Motif DE_24h DE_24h-POU4F1_MA0790.2 12 bp overlap

POU4F2 1 dataset

Motif DE_24h DE_24h-POU4F2_MA0683.2 15 bp overlap

POU4F3 1 dataset

Motif DE_24h DE_24h-POU4F3_MA0791.2 12 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 600 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 152 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 537 bp overlap

PRDM1 1 dataset

Motif DE_24h DE_24h-PRDM1_MA0508.4 7 bp overlap

PRDM6 2 datasets

ChIP HEK293 ENCFF283AJL 54 bp overlap

ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 70 bp overlap

RARA 1 dataset

Motif DE_24h DE_24h-RARA_MA0729.1 18 bp overlap

Rarb 1 dataset

Motif DE_24h DE_24h-Rarb_MA0857.1 16 bp overlap

Rarg 2 datasets

Motif DE_24h DE_24h-Rarg_MA0859.2 15 bp overlap

Motif DE_24h DE_24h-Rarg_MA0860.1 17 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 341 bp overlap

SMAD2_3 3 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 407 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 189 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 383 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 395 bp overlap

SP7 1 dataset

ChIP HEK293 ENCSR468IJT.SP7.HEK293 96 bp overlap

SREBF1 1 dataset

Motif DE_24h DE_24h-SREBF1_MA0595.1 10 bp overlap

SREBF2 1 dataset

Motif DE_24h DE_24h-SREBF2_MA0596.1 10 bp overlap

TBR1 1 dataset

Motif DE_24h DE_24h-TBR1_MA0802.2 9 bp overlap

TBX18 1 dataset

Motif DE_24h DE_24h-TBX18_MA1565.2 9 bp overlap

TBX2 1 dataset

Motif DE_24h DE_24h-TBX2_MA0688.2 9 bp overlap

TBX20 1 dataset

Motif DE_24h DE_24h-TBX20_MA0689.1 11 bp overlap

TBX21 3 datasets

Motif DE_24h DE_24h-TBX21_MA0690.3 10 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 53 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 101 bp overlap

TBX3 1 dataset

Motif DE_24h DE_24h-TBX3_MA1566.3 9 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 108 bp overlap

TRIM28 1 dataset

ChIP hESC GSE115387.TRIM28.hESC 55 bp overlap

Tbx6 1 dataset

Motif DE_24h DE_24h-Tbx6_MA1567.3 9 bp overlap

WT1 2 datasets

ChIP HEK293 ENCFF906HIR 216 bp overlap

ChIP HEK293 ENCSR966PJJ.WT1.HEK293 335 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 66 bp overlap

ZBTB8A 1 dataset

ChIP HEK293 ENCFF303WRD 160 bp overlap

ZEB2 1 dataset

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 59 bp overlap

ZKSCAN5 1 dataset

Motif DE_24h DE_24h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF189 4 datasets

ChIP HEK293 ENCFF638TIB 113 bp overlap

ChIP HEK293 ENCFF638TIB 158 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 140 bp overlap

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 143 bp overlap

ZNF257 1 dataset

Motif DE_24h DE_24h-ZNF257_MA1710.2 10 bp overlap

ZNF362 2 datasets

ChIP HEK293 ENCFF436CGE 205 bp overlap

ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 156 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 156 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 144 bp overlap

ZNF664 1 dataset

ChIP HEK293 ENCSR714LZQ.ZNF664.HEK293 176 bp overlap

ZNF75A 1 dataset

Motif DE_24h DE_24h-ZNF75A_MA2097.1 12 bp overlap

ZNF768 1 dataset

ChIP HepG2 ENCFF388QCK 402 bp overlap

ZNF770 2 datasets

ChIP HEK293 ENCFF468FCG 281 bp overlap

ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 315 bp overlap