chr5 : 143,345,889 – 143,346,435
546 bp 75 TFs 1 linked gene
This 546 bp open chromatin element is linked to NR3C1 and is bound by 75 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NR3C1 57.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:143,340,889 – 143,351,435
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
75 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP 12Z GSE129781.ARID1A.12Z 152 bp overlap
ARID3A 1 dataset
ChIP GM12878 ENCSR778UBR.ARID3A.GM12878 174 bp overlap
BCLAF1 1 dataset
ChIP GM12878 ENCFF655JCD 285 bp overlap
BORCS8-MEF2B,MEF2B 1 dataset
ChIP GM12878 ENCFF427QAI 119 bp overlap
BRD4 1 dataset
ChIP GM15850_PA1_JQ1 GSE99402.BRD4.GM15850_PA1_JQ1 126 bp overlap
CEBPD 5 datasets
Motif DE_36h DE_36h-CEBPD_MA0836.3 8 bp overlap
Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap
Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap
Motif DE_72h DE_72h-CEBPD_MA0836.3 8 bp overlap
ChIP K-562 ENCSR000BVY.CEBPD.K-562 113 bp overlap
CTCF 1 dataset
ChIP GM12869 ENCSR000DRJ.CTCF.GM12869 98 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 303 bp overlap
ESR1 24 datasets
Motif DE_36h DE_36h-ESR1_MA0112.4 15 bp overlap
Motif DE_48h DE_48h-ESR1_MA0112.4 15 bp overlap
Motif DE_60h DE_60h-ESR1_MA0112.4 15 bp overlap
Motif DE_72h DE_72h-ESR1_MA0112.4 15 bp overlap
ChIP MCF-7 GSE76893.ESR1.MCF-7 174 bp overlap
ChIP MCF-7 GSE103023.ESR1.MCF-7 241 bp overlap
ChIP MCF-7 GSE45822.ESR1.MCF-7 178 bp overlap
ChIP MCF-7-Luc_E2 GSE78284.ESR1.MCF-7-Luc_E2 178 bp overlap
ChIP MCF-7_4OH-Tam GSE117941.ESR1.MCF-7_4OH-Tam 196 bp overlap
ChIP MCF-7_ARID1A-KO_clone14 GSE123284.ESR1.MCF-7_ARID1A-KO_clone14 166 bp overlap
ChIP MCF-7_DMSO GSE125594.ESR1.MCF-7_DMSO 294 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 94 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 325 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 165 bp overlap
ChIP MCF-7_G6274 GSE117941.ESR1.MCF-7_G6274 214 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 211 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 136 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 165 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 180 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 212 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 186 bp overlap
ChIP MCF-7_shFbxo_E2_4OHT GSE119702.ESR1.MCF-7_shFbxo_E2_4OHT 147 bp overlap
ChIP MCF-7_shFbxo_OHT GSE119702.ESR1.MCF-7_shFbxo_OHT 147 bp overlap
ChIP MCF-7_shTEAD4 GSE125594.ESR1.MCF-7_shTEAD4 241 bp overlap
ESR1_D538G 1 dataset
ChIP MCF-7_dox_E2 GSE94493.ESR1_D538G.MCF-7_dox_E2 208 bp overlap
ESR1_Y537N 3 datasets
ChIP MCF-7_E2_talen GSE94493.ESR1_Y537N.MCF-7_E2_talen 186 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 319 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 181 bp overlap
ESR1_Y537S 2 datasets
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 287 bp overlap
ChIP MCF-7_dox GSE94493.ESR1_Y537S.MCF-7_dox 302 bp overlap
ESR1_pS118 1 dataset
ChIP MCF-7_E2_sc GSE117569.ESR1_pS118.MCF-7_E2_sc 344 bp overlap
ESR2 5 datasets
Motif DE_36h DE_36h-ESR2_MA0258.2 15 bp overlap
Motif DE_48h DE_48h-ESR2_MA0258.2 15 bp overlap
Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap
Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap
ChIP MDA-MB-231_estradiol GSE108979.ESR2.MDA-MB-231_estradiol 296 bp overlap
ESRRA 4 datasets
Motif DE_36h DE_36h-ESRRA_MA0592.4 9 bp overlap
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
ESRRB 4 datasets
Motif DE_36h DE_36h-ESRRB_MA0141.4 10 bp overlap
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
Motif DE_60h DE_60h-ESRRB_MA0141.4 10 bp overlap
Motif DE_72h DE_72h-ESRRB_MA0141.4 10 bp overlap
ETV5::DRGX 4 datasets
Motif DE_36h DE_36h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_60h DE_60h-ETV5DRGX_MA1944.2 12 bp overlap
Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap
EWSR1-FLI1 4 datasets
Motif DE_36h DE_36h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_60h DE_60h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
FOXA1 1 dataset
ChIP MCF-7 GSE81714.FOXA1.MCF-7 207 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 327 bp overlap
ChIP DE DE-FOXA2-1 546 bp overlap
ChIP DE DE-FOXA2-2 401 bp overlap
FOXL2 4 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 302 bp overlap
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 280 bp overlap
ChIP KGN_1513 GSE138496.FOXL2.KGN_1513 184 bp overlap
ChIP SVOG-3e_DOX-WT GSE126171.FOXL2.SVOG-3e_DOX-WT 265 bp overlap
GATA1 6 datasets
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 242 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 134 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
GATA2 6 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 286 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 414 bp overlap
ChIP K562 ENCFF830LLA 546 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 237 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 347 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 244 bp overlap
GATA3 2 datasets
ChIP MCF-7 GSE133072.GATA3.MCF-7 205 bp overlap
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 250 bp overlap
GATA4 5 datasets
ChIP A-549 GSE85002.GATA4.A-549 212 bp overlap
ChIP DE DE-GATA4-1 513 bp overlap
ChIP DE DE-GATA4-2 546 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 441 bp overlap
ChIP foregut GSE117136.GATA4.foregut 411 bp overlap
GATA6 6 datasets
ChIP DE DE-GATA6-1 501 bp overlap
ChIP DE DE-GATA6-2 517 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 546 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 301 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 481 bp overlap
ChIP foregut GSE117136.GATA6.foregut 378 bp overlap
GPS2 1 dataset
ChIP hMADS_D0_E GSE152517.GPS2.hMADS_D0_E 149 bp overlap
GRHL2 4 datasets
Motif DE_36h DE_36h-GRHL2_MA1105.3 8 bp overlap
Motif DE_48h DE_48h-GRHL2_MA1105.3 8 bp overlap
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
Hmx3 4 datasets
Motif DE_36h DE_36h-Hmx3_MA0898.2 9 bp overlap
Motif DE_48h DE_48h-Hmx3_MA0898.2 9 bp overlap
Motif DE_60h DE_60h-Hmx3_MA0898.2 9 bp overlap
Motif DE_72h DE_72h-Hmx3_MA0898.2 9 bp overlap
IKZF2 1 dataset
ChIP GM12878 ENCFF918AID 352 bp overlap
ISL2 3 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
KDM1A 1 dataset
ChIP SH-SY5Y_B3 GSE58258.KDM1A.SH-SY5Y_B3 180 bp overlap
MAFK 4 datasets
Motif DE_36h DE_36h-MAFK_MA0496.4 10 bp overlap
Motif DE_48h DE_48h-MAFK_MA0496.4 10 bp overlap
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
Motif DE_72h DE_72h-MAFK_MA0496.4 10 bp overlap
MEF2A 2 datasets
ChIP GM12878 ENCFF652BHX 109 bp overlap
ChIP GM12878 ENCSR000BKB.MEF2A.GM12878 68 bp overlap
MEF2B 1 dataset
ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 162 bp overlap
MEIS1 4 datasets
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MEIS2 2 datasets
ChIP K-562 ENCSR851BNE.MEIS2.K-562 281 bp overlap
ChIP K562 ENCFF320GSD 145 bp overlap
MLLT1 1 dataset
ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 264 bp overlap
MNT 1 dataset
ChIP Hep-G2 ENCSR730TBC.MNT.Hep-G2 196 bp overlap
MTA2 2 datasets
ChIP GM12878 ENCFF615CWQ 310 bp overlap
ChIP GM12878 ENCSR293QAR.MTA2.GM12878 354 bp overlap
Mafg 4 datasets
Motif DE_36h DE_36h-Mafg_MA0659.4 12 bp overlap
Motif DE_48h DE_48h-Mafg_MA0659.4 12 bp overlap
Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap
Motif DE_72h DE_72h-Mafg_MA0659.4 12 bp overlap
NKX2-3 3 datasets
Motif DE_36h DE_36h-NKX2-3_MA0672.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-3_MA0672.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-3_MA0672.2 8 bp overlap
NKX2-4 3 datasets
Motif DE_36h DE_36h-NKX2-4_MA2003.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-4_MA2003.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap
NKX2-8 3 datasets
Motif DE_36h DE_36h-NKX2-8_MA0673.2 8 bp overlap
Motif DE_48h DE_48h-NKX2-8_MA0673.2 8 bp overlap
Motif DE_60h DE_60h-NKX2-8_MA0673.2 8 bp overlap
NR2F1 4 datasets
Motif DE_36h DE_36h-NR2F1_MA1538.1 15 bp overlap
Motif DE_48h DE_48h-NR2F1_MA1538.1 15 bp overlap
Motif DE_60h DE_60h-NR2F1_MA1538.1 15 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1538.1 15 bp overlap
NR3C1 1 dataset
ChIP A-549 ENCSR000BHG.NR3C1.A-549 124 bp overlap
Nkx2-1 4 datasets
Motif DE_36h DE_36h-Nkx2-1_MA1994.2 7 bp overlap
Motif DE_48h DE_48h-Nkx2-1_MA1994.2 7 bp overlap
Motif DE_60h DE_60h-Nkx2-1_MA1994.2 7 bp overlap
Motif DE_72h DE_72h-Nkx2-1_MA1994.2 7 bp overlap
Nkx3-1 4 datasets
Motif DE_36h DE_36h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_48h DE_48h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_60h DE_60h-Nkx3-1_MA0124.3 7 bp overlap
Motif DE_72h DE_72h-Nkx3-1_MA0124.3 7 bp overlap
Nkx3-2 4 datasets
Motif DE_36h DE_36h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_60h DE_60h-Nkx3-2_MA0122.4 10 bp overlap
Motif DE_72h DE_72h-Nkx3-2_MA0122.4 10 bp overlap
Nr5A2 4 datasets
Motif DE_36h DE_36h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_72h DE_72h-Nr5A2_MA0505.3 9 bp overlap
PBX2 2 datasets
ChIP K-562 ENCSR263DFP.PBX2.K-562 266 bp overlap
ChIP K562 ENCFF286KMN 417 bp overlap
POLR2A 1 dataset
ChIP GM12892 ENCFF245LYF 440 bp overlap
PRDM6 1 dataset
ChIP HEK293 ENCSR892QHR.PRDM6.HEK293 402 bp overlap
RELA 1 dataset
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 214 bp overlap
REST 3 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap
RUNX3 1 dataset
ChIP GM12878 ENCFF395WHA 77 bp overlap
Runx1 4 datasets
Motif DE_36h DE_36h-Runx1_MA0002.3 9 bp overlap
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
SMAD2-3 2 datasets
ChIP HGrC1_C134W-TGF GSE138496.SMAD2-3.HGrC1_C134W-TGF 207 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 445 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 506 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 462 bp overlap
SMAD3 1 dataset
ChIP endoderm GSE29422.SMAD3.endoderm 265 bp overlap
SMAD4 2 datasets
ChIP HGrC1_C134W GSE138496.SMAD4.HGrC1_C134W 210 bp overlap
ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap
SNAI2 1 dataset
ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 170 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 330 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 430 bp overlap
Spi1 4 datasets
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 266 bp overlap
TBX18 2 datasets
ChIP K-562 ENCSR385IUC.TBX18.K-562 317 bp overlap
ChIP K562 ENCFF473CJK 351 bp overlap
TERF1 1 dataset
ChIP LCL GSE55053.TERF1.LCL 142 bp overlap
TRIM22 1 dataset
ChIP GM12878 ENCSR637QAM.TRIM22.GM12878 313 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 326 bp overlap
ZKSCAN3 3 datasets
Motif DE_48h DE_48h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_60h DE_60h-ZKSCAN3_MA1973.2 14 bp overlap
Motif DE_72h DE_72h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF211 4 datasets
Motif DE_36h DE_36h-ZNF211_MA1974.2 10 bp overlap
Motif DE_48h DE_48h-ZNF211_MA1974.2 10 bp overlap
Motif DE_60h DE_60h-ZNF211_MA1974.2 10 bp overlap
Motif DE_72h DE_72h-ZNF211_MA1974.2 10 bp overlap
ZNF317 4 datasets
Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF35 4 datasets
Motif DE_36h DE_36h-ZNF35_MA2333.1 7 bp overlap
Motif DE_48h DE_48h-ZNF35_MA2333.1 7 bp overlap
Motif DE_60h DE_60h-ZNF35_MA2333.1 7 bp overlap
Motif DE_72h DE_72h-ZNF35_MA2333.1 7 bp overlap
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