chr5 : 109,857,449 – 109,858,346
897 bp 79 TFs 1 linked gene
This 897 bp open chromatin element is linked to MAN2A1 and is bound by 79 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MAN2A1 3.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:109,852,449 – 109,863,346
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
79 transcription factors
Source
Cell type
ASCL1 1 dataset
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 161 bp overlap
Atf3 1 dataset
Motif DE_60h DE_60h-Atf3_MA1988.2 7 bp overlap
BACH1 2 datasets
ChIP H1 ENCFF282VDB 321 bp overlap
ChIP WA01 ENCSR000EBQ.BACH1.WA01 266 bp overlap
BATF 1 dataset
Motif DE_60h DE_60h-BATF_MA1634.2 7 bp overlap
BATF3 1 dataset
Motif DE_60h DE_60h-BATF3_MA0835.3 7 bp overlap
BATF::JUN 1 dataset
Motif DE_60h DE_60h-BATFJUN_MA0462.3 7 bp overlap
BCL6 2 datasets
ChIP CD4 GSE59933.BCL6.CD4 119 bp overlap
ChIP CD4 GSE59933.BCL6.CD4 127 bp overlap
BNC2 1 dataset
Motif DE_60h DE_60h-BNC2_MA1928.2 7 bp overlap
BRD3 1 dataset
ChIP MM1-S GSE43743.BRD3.MM1-S 707 bp overlap
BRD4 14 datasets
ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 444 bp overlap
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 216 bp overlap
ChIP MM1-S_DMSO GSE42161.BRD4.MM1-S_DMSO 897 bp overlap
ChIP MM1-S_JQ1_150NM GSE49224.BRD4.MM1-S_JQ1_150NM 563 bp overlap
ChIP MM1-S_JQ1_150NM GSE49224.BRD4.MM1-S_JQ1_150NM 121 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 72 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 562 bp overlap
ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 897 bp overlap
ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 867 bp overlap
ChIP MM1-S_JQ1_5UM GSE42355.BRD4.MM1-S_JQ1_5UM 521 bp overlap
ChIP MOLT-4_DMSO GSE79288.BRD4.MOLT-4_DMSO 212 bp overlap
ChIP T-cell_DMSO GSE138084.BRD4.T-cell_DMSO 553 bp overlap
ChIP T-cell_iBET GSE138084.BRD4.T-cell_iBET 469 bp overlap
ChIP T-cell_iBET-BD1 GSE138084.BRD4.T-cell_iBET-BD1 387 bp overlap
BRF1 1 dataset
ChIP H9_Activin GSE94418.BRF1.H9_Activin 148 bp overlap
Bach1::Mafk 1 dataset
Motif DE_60h DE_60h-Bach1Mafk_MA0591.2 12 bp overlap
CDK8 1 dataset
ChIP MM1-S GSE43743.CDK8.MM1-S 702 bp overlap
CDK9 6 datasets
ChIP MM1-S_DMSO GSE42161.CDK9.MM1-S_DMSO 455 bp overlap
ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 338 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 110 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 282 bp overlap
ChIP MM1-S_JQ1_50NM GSE49224.CDK9.MM1-S_JQ1_50NM 226 bp overlap
ChIP MOLT-4_JQ1 GSE79288.CDK9.MOLT-4_JQ1 185 bp overlap
CEBPA 2 datasets
ChIP HepG2 ENCFF175DFS 305 bp overlap
ChIP liver ERP002306.CEBPA.liver 223 bp overlap
CTCF 3 datasets
ChIP MM.1S ENCFF869JMQ 421 bp overlap
ChIP MM1-S ENCSR402IDP.CTCF.MM1-S 220 bp overlap
ChIP islet ERP004003.CTCF.islet 198 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF364PUR 251 bp overlap
EMSY 1 dataset
ChIP K562 ENCFF511ZZZ 255 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 251 bp overlap
ERG 1 dataset
ChIP Jurkat GSE49091.ERG.Jurkat 145 bp overlap
ETS1 1 dataset
ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 205 bp overlap
FOSL1 1 dataset
Motif DE_60h DE_60h-FOSL1_MA0477.3 9 bp overlap
FOSL2 1 dataset
Motif DE_60h DE_60h-FOSL2_MA0478.2 10 bp overlap
FOXA1 3 datasets
ChIP HepG2 ENCFF207NVJ 281 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 351 bp overlap
ChIP prostate-cancer_PDX_136 GSE130408.FOXA1.prostate-cancer_PDX_136 127 bp overlap
FOXA2 7 datasets
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 536 bp overlap
ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 281 bp overlap
ChIP Caco-2 GSE66218.FOXA2.Caco-2 164 bp overlap
ChIP DE DE-FOXA2-1 741 bp overlap
ChIP DE DE-FOXA2-2 772 bp overlap
ChIP liver ENCSR080XEY.FOXA2.liver 172 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 380 bp overlap
FOXK1 1 dataset
ChIP Hep-G2 ENCSR603BJQ.FOXK1.Hep-G2 165 bp overlap
GATA1 2 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 166 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 125 bp overlap
GATA4 5 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 273 bp overlap
ChIP DE DE-GATA4-1 605 bp overlap
ChIP DE DE-GATA4-2 651 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 417 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 498 bp overlap
GATA6 5 datasets
ChIP DE DE-GATA6-1 524 bp overlap
ChIP DE DE-GATA6-2 593 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 342 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 329 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 426 bp overlap
HNF4A 2 datasets
ChIP liver ENCFF354NRH 405 bp overlap
ChIP liver ERP002306.HNF4A.liver 136 bp overlap
JUN::JUNB 1 dataset
Motif DE_60h DE_60h-JUNJUNB_MA1132.2 8 bp overlap
JUNB 2 datasets
ChIP CD4 GSE116695.JUNB.CD4 326 bp overlap
Motif DE_60h DE_60h-JUNB_MA0490.3 9 bp overlap
Jun 1 dataset
Motif DE_60h DE_60h-Jun_MA0489.3 8 bp overlap
KDM1A 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 271 bp overlap
KMT2A 1 dataset
ChIP blood_cord GSE83671.KMT2A.blood_cord 391 bp overlap
LMO1 1 dataset
ChIP Jurkat GSE94391.LMO1.Jurkat 304 bp overlap
MAF 3 datasets
ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 451 bp overlap
Motif DE_60h DE_60h-MAF_MA1520.2 13 bp overlap
ChIP lymphocyte_Th17_IL10+_Day5 GSE101389.MAF.lymphocyte_Th17_IL10+_Day5 254 bp overlap
MAF::NFE2 1 dataset
Motif DE_60h DE_60h-MAFNFE2_MA0501.2 11 bp overlap
MAFA 1 dataset
Motif DE_60h DE_60h-MAFA_MA1521.2 13 bp overlap
MAFB 1 dataset
ChIP islet ERP004003.MAFB.islet 403 bp overlap
MAFF 6 datasets
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
ChIP HeLa-S3 ENCFF783SBT 277 bp overlap
ChIP HeLa-S3 ENCSR140DSL.MAFF.HeLa-S3 180 bp overlap
ChIP HepG2 ENCFF452YUT 199 bp overlap
ChIP K-562 ENCSR000EGI.MAFF.K-562 168 bp overlap
ChIP K562 ENCFF071YKK 281 bp overlap
MAFG 2 datasets
ChIP K-562 ENCSR818DQV.MAFG.K-562 442 bp overlap
ChIP K562 ENCFF455EEO 445 bp overlap
MAFG::NFE2L1 1 dataset
Motif DE_60h DE_60h-MAFGNFE2L1_MA0089.3 11 bp overlap
MAFK 14 datasets
ChIP A549 ENCFF371EPR 286 bp overlap
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
Motif DE_60h DE_60h-MAFK_MA0496.4 10 bp overlap
ChIP H1 ENCFF854XWE 285 bp overlap
ChIP Hep-G2 ENCSR000EDZ.MAFK.Hep-G2 247 bp overlap
ChIP HepG2 ENCFF743ZOF 181 bp overlap
ChIP HepG2 ENCFF767LDG 257 bp overlap
ChIP IMR-90 ENCFF336DHZ 149 bp overlap
ChIP K-562 ENCSR000EGX.MAFK.K-562 162 bp overlap
ChIP K562 ENCFF380WHM 281 bp overlap
ChIP MCF-7 ENCFF558JLG 361 bp overlap
ChIP MCF-7 ENCSR555PBN.MAFK.MCF-7 284 bp overlap
ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 214 bp overlap
ChIP WA01 ENCSR000EBS.MAFK.WA01 270 bp overlap
MED1 7 datasets
ChIP MM1-S_BIORU GSE45984.MED1.MM1-S_BIORU 718 bp overlap
ChIP MM1-S_DMSO GSE36354.MED1.MM1-S_DMSO 643 bp overlap
ChIP MM1-S_DMSO GSE36354.MED1.MM1-S_DMSO 204 bp overlap
ChIP MM1-S_JQ1_5000NM GSE49224.MED1.MM1-S_JQ1_5000NM 313 bp overlap
ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 605 bp overlap
ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 757 bp overlap
ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 652 bp overlap
MYB 2 datasets
ChIP CD4_Th1 GSE72266.MYB.CD4_Th1 513 bp overlap
ChIP Jurkat GSE59657.MYB.Jurkat 360 bp overlap
MYBL2 1 dataset
ChIP A-673 GSE119971.MYBL2.A-673 336 bp overlap
MYC 1 dataset
ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 311 bp overlap
Mafb 1 dataset
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Mafg 1 dataset
Motif DE_60h DE_60h-Mafg_MA0659.4 12 bp overlap
NANOG 1 dataset
ChIP hESC GSE18292.NANOG.hESC 101 bp overlap
NCOR1 1 dataset
ChIP LS180 GSE39277.NCOR1.LS180 131 bp overlap
NEUROD1 2 datasets
ChIP D283-Med GSE92582.NEUROD1.D283-Med 411 bp overlap
ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 422 bp overlap
NKX3-1 1 dataset
ChIP islet ERP004003.NKX3-1.islet 287 bp overlap
NOTCH1 1 dataset
ChIP HPBALL GSE39263.NOTCH1.HPBALL 388 bp overlap
NRL 1 dataset
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Nfe2l2 1 dataset
Motif DE_60h DE_60h-Nfe2l2_MA0150.3 11 bp overlap
PBX3 1 dataset
Motif DE_60h DE_60h-PBX3_MA1114.2 11 bp overlap
PDX1 3 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 276 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 266 bp overlap
ChIP islet ERP001456.PDX1.islet 221 bp overlap
PKNOX1 1 dataset
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
POLR2A 1 dataset
ChIP spleen ENCFF446ZGT 521 bp overlap
RAD21 2 datasets
ChIP hiPSC_parental-line GSE106870.RAD21.hiPSC_parental-line 127 bp overlap
ChIP liver ENCFF522JHE 401 bp overlap
RELA 11 datasets
ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 190 bp overlap
ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 194 bp overlap
ChIP aortic-endothelial-cell_IL1B_D2 GSE139377.RELA.aortic-endothelial-cell_IL1B_D2 213 bp overlap
ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 167 bp overlap
ChIP aortic-endothelial-cell_IL1B_D22 GSE139377.RELA.aortic-endothelial-cell_IL1B_D22 219 bp overlap
ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 219 bp overlap
ChIP aortic-endothelial-cell_IL1B_D27 GSE139377.RELA.aortic-endothelial-cell_IL1B_D27 167 bp overlap
ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 170 bp overlap
ChIP aortic-endothelial-cell_IL1B_D40 GSE139377.RELA.aortic-endothelial-cell_IL1B_D40 167 bp overlap
ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 226 bp overlap
ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 255 bp overlap
RUNX1 2 datasets
ChIP Jurkat GSE68976.RUNX1.Jurkat 459 bp overlap
ChIP Jurkat GSE76181.RUNX1.Jurkat 336 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 404 bp overlap
SMARCA4 1 dataset
ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 245 bp overlap
SOX13 1 dataset
ChIP HepG2 ENCFF062VSQ 357 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 385 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 223 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 244 bp overlap
SP1 1 dataset
ChIP liver ENCFF597LFJ 485 bp overlap
SPI1 1 dataset
ChIP DC_LPS GSE123347.SPI1.DC_LPS 132 bp overlap
SREBF1 1 dataset
Motif DE_60h DE_60h-SREBF1_MA0595.1 10 bp overlap
STAT3 1 dataset
ChIP Th1_IL-6_HyIL6 GSE130810.STAT3.Th1_IL-6_HyIL6 206 bp overlap
STAT5B 2 datasets
ChIP CD8_H9 GSE64713.STAT5B.CD8_H9 481 bp overlap
ChIP CD8_IL2 GSE64713.STAT5B.CD8_IL2 491 bp overlap
TBP 1 dataset
Motif DE_60h DE_60h-TBP_MA0108.3 7 bp overlap
TBX21 3 datasets
ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 265 bp overlap
ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 108 bp overlap
ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 570 bp overlap
ZNF143 1 dataset
ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 183 bp overlap
ZNF316 1 dataset
ChIP K562 ENCFF838QCD 301 bp overlap
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