chr5 : 55,029,649 – 55,030,875
1,226 bp 91 TFs 5 linked genes
This 1.2 kb open chromatin element is linked to 5 target genes and is bound by 91 transcription factors.
Linked Genes
5 genes
Distance
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
GZMK at TSS At TSS Proximity
GPX8 129.8 kb Distal Multiome
CCNO-DT 203.6 kb Distal Multiome
DHX29 277.3 kb Distal Multiome
MTREX 277.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:55,024,649 – 55,035,875
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
91 transcription factors
Source
Cell type
AR 1 dataset
ChIP 22Rv1_pLKO GSE109748.AR.22Rv1_pLKO 163 bp overlap
BCL11A 3 datasets
ChIP H1 ENCFF836SSR 177 bp overlap
ChIP WA01 ENCSR000BMJ.BCL11A.WA01 235 bp overlap
ChIP WA01 ENCSR000BIP.BCL11A.WA01 145 bp overlap
Bcl11B 1 dataset
Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap
CDK6 1 dataset
ChIP KB_IL GSE52469.CDK6.KB_IL 100 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 418 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF844FIP 251 bp overlap
Crx 2 datasets
Motif DE_60h DE_60h-Crx_MA0467.3 6 bp overlap
Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 385 bp overlap
EP300 3 datasets
ChIP H1 ENCFF927IYK 297 bp overlap
ChIP WA01 ENCSR000BKK.EP300.WA01 194 bp overlap
ChIP hESC GSE17917.EP300.hESC 293 bp overlap
EZH2 1 dataset
ChIP neural progenitor cell ENCFF018MKA 845 bp overlap
EZH2_phosphoT487 1 dataset
ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 216 bp overlap
FOXA1 2 datasets
ChIP MCF-7 ENCSR126YEB.FOXA1.MCF-7 59 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 265 bp overlap
FOXA2 4 datasets
ChIP DE DE-FOXA2-1 768 bp overlap
ChIP DE DE-FOXA2-2 870 bp overlap
ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 287 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 266 bp overlap
FOXE1 2 datasets
Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap
Motif DE_72h DE_72h-FOXE1_MA1487.3 12 bp overlap
FOXL2 2 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 130 bp overlap
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 210 bp overlap
FOXN3 3 datasets
Motif DE_48h DE_48h-FOXN3_MA1489.1 8 bp overlap
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
Motif DE_72h DE_72h-FOXN3_MA1489.1 8 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 359 bp overlap
GATA1 3 datasets
Motif DE_48h DE_48h-GATA1_MA0035.5 7 bp overlap
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
Motif DE_72h DE_72h-GATA1_MA0035.5 7 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 622 bp overlap
ChIP DE DE-GATA4-2 699 bp overlap
ChIP foregut GSE117136.GATA4.foregut 503 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 566 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 350 bp overlap
GATA6 7 datasets
ChIP DE DE-GATA6-1 593 bp overlap
ChIP DE DE-GATA6-2 697 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 570 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 476 bp overlap
ChIP foregut GSE117136.GATA6.foregut 491 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 446 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 330 bp overlap
GSC 2 datasets
Motif DE_60h DE_60h-GSC_MA0648.2 6 bp overlap
Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_60h DE_60h-GSC2_MA0891.2 6 bp overlap
Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap
Gfi1B 1 dataset
Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap
HDAC2 2 datasets
ChIP pre-B-cell GSE107886.HDAC2.pre-B-cell 245 bp overlap
ChIP pre-B-cell GSE107886.HDAC2.pre-B-cell 73 bp overlap
HNF4A 1 dataset
Motif DE_72h DE_72h-HNF4A_MA0114.5 9 bp overlap
HNF4G 1 dataset
Motif DE_72h DE_72h-HNF4G_MA0484.3 9 bp overlap
IKZF1 2 datasets
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 390 bp overlap
ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 105 bp overlap
IKZF3 1 dataset
ChIP pre-B-cell GSE107886.IKZF3.pre-B-cell 308 bp overlap
IRF5 1 dataset
Motif DE_72h DE_72h-IRF5_MA1420.1 14 bp overlap
Irf1 3 datasets
Motif DE_48h DE_48h-Irf1_MA0050.4 11 bp overlap
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
Motif DE_72h DE_72h-Irf1_MA0050.4 11 bp overlap
KLF14 3 datasets
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
Motif DE_60h DE_60h-KLF14_MA0740.2 9 bp overlap
Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap
KMT2A 1 dataset
ChIP L826 GSE83671.KMT2A.L826 191 bp overlap
MEF2A 2 datasets
Motif DE_60h DE_60h-MEF2A_MA0052.5 10 bp overlap
Motif DE_72h DE_72h-MEF2A_MA0052.5 10 bp overlap
MEF2B 2 datasets
Motif DE_60h DE_60h-MEF2B_MA0660.1 12 bp overlap
Motif DE_72h DE_72h-MEF2B_MA0660.1 12 bp overlap
MEF2C 2 datasets
Motif DE_60h DE_60h-MEF2C_MA0497.2 11 bp overlap
Motif DE_72h DE_72h-MEF2C_MA0497.2 11 bp overlap
MEF2D 2 datasets
Motif DE_60h DE_60h-MEF2D_MA0773.1 12 bp overlap
Motif DE_72h DE_72h-MEF2D_MA0773.1 12 bp overlap
MEIS1 3 datasets
Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
MTA2 1 dataset
ChIP pre-B-cell GSE107886.MTA2.pre-B-cell 201 bp overlap
MZF1 3 datasets
Motif DE_48h DE_48h-MZF1_MA0056.3 8 bp overlap
Motif DE_60h DE_60h-MZF1_MA0056.3 8 bp overlap
Motif DE_72h DE_72h-MZF1_MA0056.3 8 bp overlap
NANOG 2 datasets
ChIP WA01 ENCSR000BMT.NANOG.WA01 146 bp overlap
ChIP hESC GSE18292.NANOG.hESC 198 bp overlap
NFATC3 3 datasets
Motif DE_48h DE_48h-NFATC3_MA0625.3 6 bp overlap
Motif DE_60h DE_60h-NFATC3_MA0625.3 6 bp overlap
Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap
NR4A1 1 dataset
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
NR4A2 1 dataset
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
Nfatc1 3 datasets
Motif DE_48h DE_48h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_60h DE_60h-Nfatc1_MA0624.3 6 bp overlap
Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_72h DE_72h-Nr1h3Rxra_MA0494.2 16 bp overlap
OTX1 2 datasets
Motif DE_60h DE_60h-OTX1_MA0711.2 6 bp overlap
Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap
OTX2 3 datasets
Motif DE_60h DE_60h-OTX2_MA0712.3 7 bp overlap
Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap
ChIP WTC11 ENCFF634NAO 245 bp overlap
PHF8 2 datasets
ChIP A549 ENCFF815XUD 473 bp overlap
ChIP A549 ENCFF815XUD 274 bp overlap
PITX1 2 datasets
Motif DE_60h DE_60h-PITX1_MA0682.3 6 bp overlap
Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_60h DE_60h-PITX2_MA1547.2 8 bp overlap
Motif DE_72h DE_72h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_60h DE_60h-PITX3_MA0714.2 6 bp overlap
Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap
PKNOX1 3 datasets
Motif DE_48h DE_48h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_60h DE_60h-PKNOX1_MA0782.3 10 bp overlap
Motif DE_72h DE_72h-PKNOX1_MA0782.3 10 bp overlap
Pparg::Rxra 3 datasets
Motif DE_48h DE_48h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_60h DE_60h-PpargRxra_MA0065.3 13 bp overlap
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
RARA 3 datasets
Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap
ChIP hiPSC_D3 GSE109172.RARA.hiPSC_D3 489 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 434 bp overlap
RARA::RXRA 2 datasets
Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap
Motif DE_72h DE_72h-RARARXRA_MA0159.1 17 bp overlap
RFX2 3 datasets
Motif DE_48h DE_48h-RFX2_MA0600.3 14 bp overlap
Motif DE_60h DE_60h-RFX2_MA0600.3 14 bp overlap
Motif DE_72h DE_72h-RFX2_MA0600.3 14 bp overlap
RFX5 3 datasets
Motif DE_48h DE_48h-RFX5_MA0510.3 14 bp overlap
Motif DE_60h DE_60h-RFX5_MA0510.3 14 bp overlap
Motif DE_72h DE_72h-RFX5_MA0510.3 14 bp overlap
RHOXF1 2 datasets
Motif DE_60h DE_60h-RHOXF1_MA0719.2 6 bp overlap
Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap
RNF2 1 dataset
ChIP A-549 ENCSR798EGJ.RNF2.A-549 65 bp overlap
RUNX1 2 datasets
ChIP 697 GSE138031.RUNX1.697 314 bp overlap
ChIP NALM-6 GSE126300.RUNX1.NALM-6 287 bp overlap
RUNX2 1 dataset
Motif DE_72h DE_72h-RUNX2_MA0511.2 9 bp overlap
Rarb 1 dataset
Motif DE_72h DE_72h-Rarb_MA0858.1 17 bp overlap
Rarg 1 dataset
Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap
Runx1 1 dataset
Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 564 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 235 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 329 bp overlap
SMAD3 2 datasets
ChIP LX2_CALCIPOTRIOL_TGFB1 GSE38103.SMAD3.LX2_CALCIPOTRIOL_TGFB1 166 bp overlap
ChIP endoderm GSE29422.SMAD3.endoderm 187 bp overlap
SMARCA4 2 datasets
ChIP hiPSC GSE124903.SMARCA4.hiPSC 270 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 202 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 229 bp overlap
SOX10 3 datasets
Motif DE_48h DE_48h-SOX10_MA0442.3 6 bp overlap
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 367 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 528 bp overlap
SOX2 4 datasets
ChIP HNSC GSE69479.SOX2.HNSC 569 bp overlap
ChIP hESC GSE18292.SOX2.hESC 141 bp overlap
ChIP hESC GSE18292.SOX2.hESC 95 bp overlap
ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 322 bp overlap
SOX21 1 dataset
ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 308 bp overlap
SOX4 3 datasets
Motif DE_48h DE_48h-SOX4_MA0867.3 8 bp overlap
Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 174 bp overlap
SP3 3 datasets
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
Motif DE_60h DE_60h-SP3_MA0746.3 11 bp overlap
Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap
SP4 3 datasets
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap
Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap
SREBF2 3 datasets
Motif DE_48h DE_48h-SREBF2_MA0596.1 10 bp overlap
Motif DE_60h DE_60h-SREBF2_MA0596.1 10 bp overlap
Motif DE_72h DE_72h-SREBF2_MA0596.1 10 bp overlap
Sox17 3 datasets
Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap
Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap
Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap
Sox6 3 datasets
Motif DE_48h DE_48h-Sox6_MA0515.1 10 bp overlap
Motif DE_60h DE_60h-Sox6_MA0515.1 10 bp overlap
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Sox7 3 datasets
Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap
Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap
Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 497 bp overlap
ZIC4 3 datasets
Motif DE_48h DE_48h-ZIC4_MA0751.2 14 bp overlap
Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap
Motif DE_72h DE_72h-ZIC4_MA0751.2 14 bp overlap
ZNF317 3 datasets
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF320 2 datasets
Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap
Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap
ZNF384 2 datasets
Motif DE_60h DE_60h-ZNF384_MA1125.2 8 bp overlap
Motif DE_72h DE_72h-ZNF384_MA1125.2 8 bp overlap
ZNF440 1 dataset
ChIP HEK293T GSE78099.ZNF440.HEK293T 245 bp overlap
ZNF449 3 datasets
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZSCAN29 3 datasets
Motif DE_48h DE_48h-ZSCAN29_MA1602.2 11 bp overlap
Motif DE_60h DE_60h-ZSCAN29_MA1602.2 11 bp overlap
Motif DE_72h DE_72h-ZSCAN29_MA1602.2 11 bp overlap
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