chr4 : 175,469,549 – 175,469,915
366 bp 62 TFs 1 linked gene
This 366 bp open chromatin element is linked to ENSG00000249945 and is bound by 62 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000249945 2.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:175,464,549 – 175,474,915
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
62 transcription factors
Source
Cell type
AHR 1 dataset
ChIP MCF-7_TCDD_45min GSE90550.AHR.MCF-7_TCDD_45min 206 bp overlap
AR 2 datasets
ChIP MCF-7 ERP001226.AR.MCF-7 177 bp overlap
ChIP myofibroblast GSE90772.AR.myofibroblast 296 bp overlap
ARID1A 7 datasets
ChIP 12Z GSE129781.ARID1A.12Z 340 bp overlap
ChIP MCF-7 GSE123284.ARID1A.MCF-7 359 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 366 bp overlap
ChIP MCF-7_DCDT GSE123284.ARID1A.MCF-7_DCDT 308 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 207 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 86 bp overlap
ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 337 bp overlap
BAF155 1 dataset
ChIP VCaP_shERG GSE110655.BAF155.VCaP_shERG 262 bp overlap
BRD2 16 datasets
ChIP MDA-MB-231_BAZ2AsiRNA GSE116879.BRD2.MDA-MB-231_BAZ2AsiRNA 366 bp overlap
ChIP MDA-MB-231_BAZ2BsiRNA GSE116879.BRD2.MDA-MB-231_BAZ2BsiRNA 366 bp overlap
ChIP MDA-MB-231_DMSO GSE116879.BRD2.MDA-MB-231_DMSO 365 bp overlap
ChIP MDA-MB-231_DMSO_rDNA GSE116879.BRD2.MDA-MB-231_DMSO_rDNA 365 bp overlap
ChIP MDA-MB-231_JQ1 GSE116879.BRD2.MDA-MB-231_JQ1 121 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801 GSE116879.BRD2.MDA-MB-231_JQ1_MGSK2801 223 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801_rDNA GSE116879.BRD2.MDA-MB-231_JQ1_MGSK2801_rDNA 223 bp overlap
ChIP MDA-MB-231_JQ1_rDNA GSE116879.BRD2.MDA-MB-231_JQ1_rDNA 121 bp overlap
ChIP MDA-MB-231_MGSK2801 GSE116879.BRD2.MDA-MB-231_MGSK2801 366 bp overlap
ChIP MDA-MB-231_MGSK2801_rDNA GSE116879.BRD2.MDA-MB-231_MGSK2801_rDNA 366 bp overlap
ChIP MDA-MB-231_NTsiRNA GSE116879.BRD2.MDA-MB-231_NTsiRNA 366 bp overlap
ChIP MDA-MB-231_NTsiRNA_JQ1 GSE116879.BRD2.MDA-MB-231_NTsiRNA_JQ1 366 bp overlap
ChIP SK-MEL-147 GSE94488.BRD2.SK-MEL-147 263 bp overlap
ChIP SUM159PT_DMSO GSE116879.BRD2.SUM159PT_DMSO 366 bp overlap
ChIP SUM159PT_JQ1 GSE116879.BRD2.SUM159PT_JQ1 275 bp overlap
ChIP SUM159PT_MGSK2801 GSE116879.BRD2.SUM159PT_MGSK2801 362 bp overlap
BRD4 17 datasets
ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 208 bp overlap
ChIP MCF-7_ARID1A-KO GSE123284.BRD4.MCF-7_ARID1A-KO 366 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 366 bp overlap
ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 148 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 306 bp overlap
ChIP MDA-MB-231_JQ1-neg_L GSE136151.BRD4.MDA-MB-231_JQ1-neg_L 366 bp overlap
ChIP SUM159PT_100nMtrametinib_1h GSE87418.BRD4.SUM159PT_100nMtrametinib_1h 366 bp overlap
ChIP SUM159PT_100nMtrametinib_4h GSE87418.BRD4.SUM159PT_100nMtrametinib_4h 366 bp overlap
ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 333 bp overlap
ChIP SUM159PT_100nMtrametinib_8h GSE87418.BRD4.SUM159PT_100nMtrametinib_8h 366 bp overlap
ChIP SUM159PT_30nMbortezomib_8h GSE87418.BRD4.SUM159PT_30nMbortezomib_8h 338 bp overlap
ChIP SUM159PT_DMSO_48h GSE87418.BRD4.SUM159PT_DMSO_48h 199 bp overlap
ChIP SUM159PT_DMSO_72h GSE87418.BRD4.SUM159PT_DMSO_72h 341 bp overlap
ChIP SUM159PT_DMSO_8h GSE87418.BRD4.SUM159PT_DMSO_8h 366 bp overlap
ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 260 bp overlap
ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 366 bp overlap
ChIP SUM159PT_shMYC_dox_48h GSE87418.BRD4.SUM159PT_shMYC_dox_48h 366 bp overlap
BRD9 3 datasets
ChIP MDA-MB-231_DMSO GSE116879.BRD9.MDA-MB-231_DMSO 241 bp overlap
ChIP MDA-MB-231_JQ1_MGSK2801 GSE116879.BRD9.MDA-MB-231_JQ1_MGSK2801 162 bp overlap
ChIP MDA-MB-231_MGSK2801 GSE116879.BRD9.MDA-MB-231_MGSK2801 352 bp overlap
CBX1 1 dataset
ChIP Hep-G2 ENCSR819WZE.CBX1.Hep-G2 260 bp overlap
CREBBP 2 datasets
ChIP MCF-7 ERP000901.CREBBP.MCF-7 187 bp overlap
ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 119 bp overlap
EBF3 1 dataset
Motif DE_12h DE_12h-EBF3_MA1637.2 9 bp overlap
ERF::HOXB13 1 dataset
Motif DE_12h DE_12h-ERFHOXB13_MA1937.2 13 bp overlap
ESR1 16 datasets
ChIP MCF-7 GSE41561.ESR1.MCF-7 177 bp overlap
ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.ESR1.MCF-7_ARID1A-KO_4-OHT 174 bp overlap
ChIP MCF-7_D538G_DMSO GSE148277.ESR1.MCF-7_D538G_DMSO 241 bp overlap
ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 317 bp overlap
ChIP MCF-7_E2_talen GSE94493.ESR1.MCF-7_E2_talen 191 bp overlap
ChIP MCF-7_PROG GSE68355.ESR1.MCF-7_PROG 211 bp overlap
ChIP MCF-7_RAD001 GSE103023.ESR1.MCF-7_RAD001 190 bp overlap
ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 317 bp overlap
ChIP MCF-7_estradiol-DHT_4h GSE99626.ESR1.MCF-7_estradiol-DHT_4h 331 bp overlap
ChIP MCF-7_estradiol-Dex_4h GSE99626.ESR1.MCF-7_estradiol-Dex_4h 181 bp overlap
ChIP MCF-7_estradiol_45min GSE99626.ESR1.MCF-7_estradiol_45min 175 bp overlap
ChIP MCF-7_estradiol_4h GSE99626.ESR1.MCF-7_estradiol_4h 363 bp overlap
ChIP MCF-7_jc5849 GSE126004.ESR1.MCF-7_jc5849 309 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 312 bp overlap
ChIP MCF-7_jc5856 GSE126004.ESR1.MCF-7_jc5856 258 bp overlap
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.ESR1.MCF-7_parental_4-hydroxytamoxifen 227 bp overlap
ESR1_Y537N 2 datasets
ChIP MCF-7_dox GSE94493.ESR1_Y537N.MCF-7_dox 235 bp overlap
ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 238 bp overlap
ESR1_Y537S 1 dataset
ChIP MCF-7_E2 GSE94493.ESR1_Y537S.MCF-7_E2 172 bp overlap
ESRRA 2 datasets
ChIP BT-474_EGF GSE81651.ESRRA.BT-474_EGF 176 bp overlap
ChIP BT-474_HRG GSE81651.ESRRA.BT-474_HRG 284 bp overlap
Ebf2 1 dataset
Motif DE_12h DE_12h-Ebf2_MA1604.2 9 bp overlap
FOXA1 15 datasets
ChIP 22Rv1 GSE96652.FOXA1.22Rv1 366 bp overlap
ChIP 22Rv1_CST GSE123618.FOXA1.22Rv1_CST 175 bp overlap
ChIP 22Rv1_CST_Crispr-36 GSE123618.FOXA1.22Rv1_CST_Crispr-36 122 bp overlap
ChIP 22Rv1_CST_Crispr_WT3 GSE123618.FOXA1.22Rv1_CST_Crispr_WT3 209 bp overlap
ChIP MCF-7 GSE81714.FOXA1.MCF-7 354 bp overlap
ChIP MCF-7 GSE72249.FOXA1.MCF-7 181 bp overlap
ChIP MCF-7 GSE80808.FOXA1.MCF-7 217 bp overlap
ChIP MCF-7_4OH-Tam GSE75201.FOXA1.MCF-7_4OH-Tam 116 bp overlap
ChIP MCF-7_DOX-neg GSE124654.FOXA1.MCF-7_DOX-neg 306 bp overlap
ChIP MCF-7_JC4690 GSE126004.FOXA1.MCF-7_JC4690 333 bp overlap
ChIP MCF-7_JC4692 GSE126004.FOXA1.MCF-7_JC4692 301 bp overlap
ChIP MCF-7_JC4693 GSE126004.FOXA1.MCF-7_JC4693 225 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 303 bp overlap
ChIP ZR-75-1_vehicle_ab2 GSE112969.FOXA1.ZR-75-1_vehicle_ab2 250 bp overlap
ChIP ZR751_E2_TAM ERP000380.FOXA1.ZR751_E2_TAM 164 bp overlap
FOXA2 2 datasets
ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 228 bp overlap
ChIP PANC-1 GSE119930.FOXA2.PANC-1 261 bp overlap
FOXE1 1 dataset
Motif DE_12h DE_12h-FOXE1_MA1487.3 12 bp overlap
FOXN3 1 dataset
Motif DE_12h DE_12h-FOXN3_MA1489.1 8 bp overlap
GATA2 2 datasets
ChIP ESF GSE108408.GATA2.ESF 174 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 175 bp overlap
GATA3 2 datasets
ChIP MCF-7_E2 GSE29073.GATA3.MCF-7_E2 144 bp overlap
ChIP T-47D ENCSR000BMX.GATA3.T-47D 122 bp overlap
GRHL2 1 dataset
ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 281 bp overlap
HDAC1 1 dataset
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 260 bp overlap
HDAC2 1 dataset
ChIP MCF-7 ENCSR000BTP.HDAC2.MCF-7 157 bp overlap
HIF1A 1 dataset
ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 227 bp overlap
JUND 1 dataset
ChIP HCT-116 ENCSR000BSA.JUND.HCT-116 136 bp overlap
KDM5B 1 dataset
ChIP HCC2157 GSE46055.KDM5B.HCC2157 225 bp overlap
MAX 1 dataset
ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 265 bp overlap
MED1 3 datasets
ChIP MCF-7_SHCTR GSE60270.MED1.MCF-7_SHCTR 60 bp overlap
ChIP VCaP_Veh GSE125245.MED1.VCaP_Veh 213 bp overlap
ChIP hMSC-TERT4_undifferentiated GSE113253.MED1.hMSC-TERT4_undifferentiated 263 bp overlap
MYCN 1 dataset
ChIP SH-EP_pRRL-MYCN GSE111905.MYCN.SH-EP_pRRL-MYCN 91 bp overlap
NELFE 1 dataset
ChIP HeLa GSE125534.NELFE.HeLa 338 bp overlap
NFIB 4 datasets
ChIP MCF-7 ENCFF799WGQ 262 bp overlap
ChIP MCF-7 ENCFF925CGH 175 bp overlap
ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 301 bp overlap
ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 284 bp overlap
NFIC 2 datasets
ChIP SK-N-SH ENCFF965AKM 300 bp overlap
ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 276 bp overlap
NR3C1 2 datasets
ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 236 bp overlap
ChIP HeLa-B2_P65KD_TA_TNFA GSE24518.NR3C1.HeLa-B2_P65KD_TA_TNFA 118 bp overlap
NRF1 1 dataset
ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 205 bp overlap
NRIP1 2 datasets
ChIP MCF-7 ERP005838.NRIP1.MCF-7 182 bp overlap
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 210 bp overlap
PGR 1 dataset
ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 197 bp overlap
PHIP 1 dataset
ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 366 bp overlap
POU2F1 1 dataset
ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 317 bp overlap
POU2F2 1 dataset
ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 185 bp overlap
RAD21 1 dataset
ChIP MCF-7 GSE72082.RAD21.MCF-7 121 bp overlap
RB1 1 dataset
ChIP MCF-7_siH1.2 GSE98728.RB1.MCF-7_siH1.2 176 bp overlap
RELA 3 datasets
ChIP HeLa-B2_DMSO GSE24518.RELA.HeLa-B2_DMSO 141 bp overlap
ChIP HeLa-B2_TNFA GSE24518.RELA.HeLa-B2_TNFA 167 bp overlap
ChIP MCF-7_E2_45m GSE67295.RELA.MCF-7_E2_45m 167 bp overlap
Rhox11 1 dataset
Motif DE_12h DE_12h-Rhox11_MA0629.2 9 bp overlap
SIN3A 1 dataset
ChIP MCF-7 ENCSR000BUM.SIN3A.MCF-7 267 bp overlap
SMAD3 3 datasets
ChIP HCC1954 GSE104760.SMAD3.HCC1954 336 bp overlap
ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 296 bp overlap
ChIP NCI-H441_SIITTF1 GSE51509.SMAD3.NCI-H441_SIITTF1 76 bp overlap
SMARCA4 10 datasets
ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 178 bp overlap
ChIP A-549_AG15687 GSE132290.SMARCA4.A-549_AG15687 205 bp overlap
ChIP A-549_AG15688 GSE132290.SMARCA4.A-549_AG15688 366 bp overlap
ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 82 bp overlap
ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 92 bp overlap
ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 100 bp overlap
ChIP MCF-7 GSE123284.SMARCA4.MCF-7 366 bp overlap
ChIP MCF-7 GSE140185.SMARCA4.MCF-7 74 bp overlap
ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 192 bp overlap
ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 366 bp overlap
SMARCB1 5 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 366 bp overlap
ChIP MCF-7_DCDT GSE123284.SMARCB1.MCF-7_DCDT 354 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.SMARCB1.MCF-7_Fulvestrant 257 bp overlap
ChIP MCF-7_JQ1 GSE123284.SMARCB1.MCF-7_JQ1 307 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 361 bp overlap
SPDEF 1 dataset
ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 178 bp overlap
SS18-SSX 1 dataset
ChIP fibroblast_23aa-SSX-Tail GSE139053.SS18-SSX.fibroblast_23aa-SSX-Tail 247 bp overlap
STAG1 2 datasets
ChIP HeLa GSE126990.STAG1.HeLa 366 bp overlap
ChIP HeLa-Kyoto GSE138405.STAG1.HeLa-Kyoto 366 bp overlap
STAT3 3 datasets
ChIP BT-474 GSE152203.STAT3.BT-474 151 bp overlap
ChIP MCF-7 GSE152203.STAT3.MCF-7 159 bp overlap
ChIP MDA-MB-231 GSE152203.STAT3.MDA-MB-231 196 bp overlap
TEAD4 2 datasets
ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 366 bp overlap
ChIP PC-9_2DF_DMSO GSE131687.TEAD4.PC-9_2DF_DMSO 84 bp overlap
TFAP2A 3 datasets
ChIP MCF-7 GSE60270.TFAP2A.MCF-7 186 bp overlap
ChIP MCF-7_E2 GSE60270.TFAP2A.MCF-7_E2 268 bp overlap
ChIP WA09 GSE105081.TFAP2A.WA09 166 bp overlap
TFAP2B 1 dataset
Motif DE_12h DE_12h-TFAP2B_MA0812.2 9 bp overlap
TFAP2C 4 datasets
ChIP HCC1954 GSE126897.TFAP2C.HCC1954 321 bp overlap
ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 285 bp overlap
ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 289 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 248 bp overlap
TRPS1 1 dataset
ChIP MCF-7 GSE133072.TRPS1.MCF-7 91 bp overlap
TWIST1 1 dataset
ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 151 bp overlap
YY1AP1 2 datasets
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 366 bp overlap
ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 366 bp overlap
ZMYND8 1 dataset
ChIP MDA-MB-231 GSE108833.ZMYND8.MDA-MB-231 366 bp overlap
ZNF770 1 dataset
Motif DE_12h DE_12h-ZNF770_MA2099.1 8 bp overlap
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