chr4 : 112,908,446 – 112,908,917

471 bp 92 TFs 0 linked genes

This 471 bp open chromatin element has no linked target genes and is bound by 92 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

92 transcription factors

Arid5a 1 dataset

Motif DE_36h DE_36h-Arid5a_MA0602.2 8 bp overlap

BRD2 1 dataset

ChIP HCC1806_BAZ2BsiRNA GSE116879.BRD2.HCC1806_BAZ2BsiRNA 190 bp overlap

CHD7 2 datasets

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 183 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 191 bp overlap

CLOCK 1 dataset

ChIP BA40_0 GSE96659.CLOCK.BA40_0 151 bp overlap

CREB1 1 dataset

Motif DE_36h DE_36h-CREB1_MA0018.5 8 bp overlap

DUX4 2 datasets

Motif DE_24h DE_24h-DUX4_MA0468.1 11 bp overlap

Motif DE_36h DE_36h-DUX4_MA0468.1 11 bp overlap

Dmrt1 1 dataset

Motif DE_24h DE_24h-Dmrt1_MA1603.2 9 bp overlap

E2F3 1 dataset

Motif DE_36h DE_36h-E2F3_MA0469.4 14 bp overlap

E2F7 1 dataset

Motif DE_36h DE_36h-E2F7_MA0758.1 14 bp overlap

EHF 2 datasets

Motif DE_24h DE_24h-EHF_MA0598.4 9 bp overlap

Motif DE_36h DE_36h-EHF_MA0598.4 9 bp overlap

ELF1 3 datasets

Motif DE_24h DE_24h-ELF1_MA0473.4 9 bp overlap

Motif DE_36h DE_36h-ELF1_MA0473.4 9 bp overlap

ChIP SK-N-MC_SHFLI_96H GSE61944.ELF1.SK-N-MC_SHFLI_96H 392 bp overlap

ELF3 2 datasets

Motif DE_24h DE_24h-ELF3_MA0640.3 9 bp overlap

Motif DE_36h DE_36h-ELF3_MA0640.3 9 bp overlap

ELK4 2 datasets

Motif DE_24h DE_24h-ELK4_MA0076.3 9 bp overlap

Motif DE_36h DE_36h-ELK4_MA0076.3 9 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 223 bp overlap

ERF::FOXI1 2 datasets

Motif DE_24h DE_24h-ERFFOXI1_MA1935.2 10 bp overlap

Motif DE_36h DE_36h-ERFFOXI1_MA1935.2 10 bp overlap

ERG 1 dataset

ChIP RWPE-1 GSE114241.ERG.RWPE-1 338 bp overlap

ETV1 2 datasets

Motif DE_24h DE_24h-ETV1_MA0761.3 9 bp overlap

Motif DE_36h DE_36h-ETV1_MA0761.3 9 bp overlap

ETV2::FOXI1 2 datasets

Motif DE_24h DE_24h-ETV2FOXI1_MA1942.2 11 bp overlap

Motif DE_36h DE_36h-ETV2FOXI1_MA1942.2 11 bp overlap

Erg 2 datasets

Motif DE_24h DE_24h-Erg_MA0474.4 10 bp overlap

Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap

FLI1 7 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 471 bp overlap

ChIP A-673_2_KRAB_eSOX2_1 GSE106914.FLI1.A-673_2_KRAB_eSOX2_1 224 bp overlap

ChIP A-673_D11 GSE129155.FLI1.A-673_D11 387 bp overlap

ChIP A-673_D14 GSE129155.FLI1.A-673_D14 381 bp overlap

ChIP A-673_D17 GSE129155.FLI1.A-673_D17 452 bp overlap

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 123 bp overlap

ChIP HUVEC-C GSE109695.FLI1.HUVEC-C 150 bp overlap

FLI1::FOXI1 2 datasets

Motif DE_24h DE_24h-FLI1FOXI1_MA1950.2 11 bp overlap

Motif DE_36h DE_36h-FLI1FOXI1_MA1950.2 11 bp overlap

FOS 2 datasets

ChIP endothelial cell of umbilical vein ENCFF415XBG 319 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 454 bp overlap

FOXJ2::ELF1 2 datasets

Motif DE_24h DE_24h-FOXJ2ELF1_MA1952.2 11 bp overlap

Motif DE_36h DE_36h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXO1::ELF1 2 datasets

Motif DE_24h DE_24h-FOXO1ELF1_MA1953.2 13 bp overlap

Motif DE_36h DE_36h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXO1::ELK1 2 datasets

Motif DE_24h DE_24h-FOXO1ELK1_MA1954.2 13 bp overlap

Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap

FOXO1::ELK3 2 datasets

Motif DE_24h DE_24h-FOXO1ELK3_MA1955.2 13 bp overlap

Motif DE_36h DE_36h-FOXO1ELK3_MA1955.2 13 bp overlap

GABPA 2 datasets

Motif DE_24h DE_24h-GABPA_MA0062.4 10 bp overlap

Motif DE_36h DE_36h-GABPA_MA0062.4 10 bp overlap

GABPB1 1 dataset

ChIP K-562 ENCSR138YYY.GABPB1.K-562 227 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 265 bp overlap

GATA6 7 datasets

ChIP DE DE-GATA6-2 278 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 384 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 444 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 468 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 342 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 455 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 459 bp overlap

GFI1 1 dataset

Motif DE_36h DE_36h-GFI1_MA0038.3 11 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 221 bp overlap

Hic1 1 dataset

Motif DE_36h DE_36h-Hic1_MA0739.2 8 bp overlap

IKZF1 2 datasets

Motif DE_24h DE_24h-IKZF1_MA1508.2 8 bp overlap

Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap

IKZF2 1 dataset

Motif DE_24h DE_24h-IKZF2_MA2326.1 6 bp overlap

Ikzf3 2 datasets

Motif DE_24h DE_24h-Ikzf3_MA1992.2 9 bp overlap

Motif DE_36h DE_36h-Ikzf3_MA1992.2 9 bp overlap

JUN 6 datasets

ChIP DE_D1 S08-DE-d1-JUN-exp1 471 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 346 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 446 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 270 bp overlap

ChIP HAEC_IL1b_4h GSE89970.JUN.HAEC_IL1b_4h 129 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 471 bp overlap

JUND 1 dataset

ChIP SK-N-SH ENCSR000BSK.JUND.SK-N-SH 167 bp overlap

LMO2 1 dataset

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 265 bp overlap

MAF::NFE2 2 datasets

Motif DE_24h DE_24h-MAFNFE2_MA0501.2 11 bp overlap

Motif DE_36h DE_36h-MAFNFE2_MA0501.2 11 bp overlap

MAFG::NFE2L1 2 datasets

Motif DE_24h DE_24h-MAFGNFE2L1_MA0089.3 11 bp overlap

Motif DE_36h DE_36h-MAFGNFE2L1_MA0089.3 11 bp overlap

MAFK 2 datasets

Motif DE_24h DE_24h-MAFK_MA0496.4 10 bp overlap

Motif DE_36h DE_36h-MAFK_MA0496.4 10 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 402 bp overlap

MSC 1 dataset

Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 291 bp overlap

MYOD1 1 dataset

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 181 bp overlap

Mafg 2 datasets

Motif DE_24h DE_24h-Mafg_MA0659.4 12 bp overlap

Motif DE_36h DE_36h-Mafg_MA0659.4 12 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 183 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 179 bp overlap

NEUROD1 3 datasets

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 159 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 343 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 244 bp overlap

NFIC 1 dataset

ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 199 bp overlap

NFYA 2 datasets

Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap

Motif DE_36h DE_36h-NFYA_MA0060.4 8 bp overlap

NFYB 2 datasets

Motif DE_24h DE_24h-NFYB_MA0502.3 9 bp overlap

Motif DE_36h DE_36h-NFYB_MA0502.3 9 bp overlap

NFYC 2 datasets

Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap

Motif DE_36h DE_36h-NFYC_MA1644.2 7 bp overlap

NR2C1 1 dataset

Motif DE_36h DE_36h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_36h DE_36h-NR2C2_MA1536.2 6 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 394 bp overlap

Nfe2l2 2 datasets

Motif DE_24h DE_24h-Nfe2l2_MA0150.3 11 bp overlap

Motif DE_36h DE_36h-Nfe2l2_MA0150.3 11 bp overlap

Nr1H2 1 dataset

Motif DE_36h DE_36h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_36h DE_36h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_36h DE_36h-Nr1h3_MA2337.1 6 bp overlap

ONECUT1 2 datasets

Motif DE_24h DE_24h-ONECUT1_MA0679.3 9 bp overlap

Motif DE_36h DE_36h-ONECUT1_MA0679.3 9 bp overlap

RELA 1 dataset

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 168 bp overlap

RORA 2 datasets

Motif DE_36h DE_36h-RORA_MA0071.1 10 bp overlap

Motif DE_36h DE_36h-RORA_MA0072.2 11 bp overlap

RORB 1 dataset

Motif DE_36h DE_36h-RORB_MA1150.2 10 bp overlap

RORC 1 dataset

Motif DE_36h DE_36h-RORC_MA1151.2 10 bp overlap

RUNX1 1 dataset

ChIP MV4-11 GSE79899.RUNX1.MV4-11 145 bp overlap

RUNX3 1 dataset

Motif DE_36h DE_36h-RUNX3_MA0684.3 8 bp overlap

Rarb 1 dataset

Motif DE_36h DE_36h-Rarb_MA0858.1 17 bp overlap

Rhox11 1 dataset

Motif DE_36h DE_36h-Rhox11_MA0629.2 9 bp overlap

SMAD2 1 dataset

Motif DE_36h DE_36h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 381 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 471 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 471 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 433 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 465 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 471 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 392 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 397 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 179 bp overlap

SMAD4 1 dataset

ChIP HGrC1_EV GSE138496.SMAD4.HGrC1_EV 129 bp overlap

SMARCA4 5 datasets

ChIP TTC-1240 GSE124903.SMARCA4.TTC-1240 254 bp overlap

ChIP TTC-1240_R377H GSE124903.SMARCA4.TTC-1240_R377H 471 bp overlap

ChIP TTC-1240_SMARCB1-FL GSE124903.SMARCA4.TTC-1240_SMARCB1-FL 283 bp overlap

ChIP TTC-1240_delC GSE124903.SMARCA4.TTC-1240_delC 371 bp overlap

ChIP TTC-1240_empty GSE124903.SMARCA4.TTC-1240_empty 353 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 308 bp overlap

SMARCC1 4 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 180 bp overlap

ChIP TTC-1240_SMARCB1-FL GSE124903.SMARCC1.TTC-1240_SMARCB1-FL 214 bp overlap

ChIP TTC-1240_delC GSE124903.SMARCC1.TTC-1240_delC 471 bp overlap

ChIP TTC-1240_empty GSE124903.SMARCC1.TTC-1240_empty 306 bp overlap

SOX10 1 dataset

Motif DE_24h DE_24h-SOX10_MA0442.3 6 bp overlap

SOX8 1 dataset

ChIP RH4 GSE116344.SOX8.RH4 220 bp overlap

SPI1 6 datasets

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 371 bp overlap

ChIP CTV-1_delQA GSE128835.SPI1.CTV-1_delQA 184 bp overlap

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 166 bp overlap

ChIP HL-60 ENCFF645GBT 271 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 189 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 171 bp overlap

SREBF2 2 datasets

Motif DE_24h DE_24h-SREBF2_MA0596.1 10 bp overlap

Motif DE_36h DE_36h-SREBF2_MA0596.1 10 bp overlap

T 1 dataset

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 231 bp overlap

TCF12 1 dataset

ChIP SK-N-SH ENCFF147AHB 295 bp overlap

TEAD4 2 datasets

Motif DE_24h DE_24h-TEAD4_MA0809.3 8 bp overlap

Motif DE_36h DE_36h-TEAD4_MA0809.3 8 bp overlap

THRB 3 datasets

Motif DE_24h DE_24h-THRB_MA1575.2 17 bp overlap

Motif DE_36h DE_36h-THRB_MA1575.2 17 bp overlap

Motif DE_36h DE_36h-THRB_MA1576.2 18 bp overlap

Tcf21 1 dataset

Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap

YY1 1 dataset

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 274 bp overlap

ZKSCAN5 2 datasets

Motif DE_24h DE_24h-ZKSCAN5_MA1652.2 9 bp overlap

Motif DE_36h DE_36h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF263 1 dataset

ChIP HEK293 GSE76494.ZNF263.HEK293 125 bp overlap

ZNF274 1 dataset

Motif DE_24h DE_24h-ZNF274_MA1592.2 12 bp overlap

Zic1::Zic2 2 datasets

Motif DE_24h DE_24h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_36h DE_36h-Zic1Zic2_MA1628.2 7 bp overlap

Zic3 2 datasets

Motif DE_24h DE_24h-Zic3_MA0697.3 7 bp overlap

Motif DE_36h DE_36h-Zic3_MA0697.3 7 bp overlap