chr4 : 110,641,211 – 110,641,759
548 bp 68 TFs 1 linked gene
This 548 bp open chromatin element is linked to PITX2 and is bound by 68 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PITX2 8.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:110,636,211 – 110,646,759
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
68 transcription factors
Source
Cell type
ASH2L 2 datasets
ChIP H1 ENCFF399KAM 548 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 532 bp overlap
Ahr::Arnt 2 datasets
Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap
Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap
BCOR 3 datasets
ChIP WA01 GSE104690.BCOR.WA01 548 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 476 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 424 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 548 bp overlap
CBX7 2 datasets
ChIP hESC GSE133412.CBX7.hESC 240 bp overlap
ChIP hESC_TKO GSE133412.CBX7.hESC_TKO 239 bp overlap
CHD1 1 dataset
ChIP WA01 ENCSR000AQK.CHD1.WA01 517 bp overlap
CTBP2 2 datasets
ChIP H1 ENCFF329MAX 482 bp overlap
ChIP WA01 ENCSR000EUO.CTBP2.WA01 488 bp overlap
CTCF 2 datasets
Motif DE_12h DE_12h-CTCF_MA1929.2 31 bp overlap
ChIP HUDEP-2_30min GSE104676.CTCF.HUDEP-2_30min 63 bp overlap
E2F6 3 datasets
Motif DE_12h DE_12h-E2F6_MA0471.3 8 bp overlap
ChIP H1 ENCFF785DWK 401 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 213 bp overlap
EGR1 1 dataset
ChIP A-375 GSE116190.EGR1.A-375 331 bp overlap
ERG 2 datasets
ChIP SKNO-1 GSE23730.ERG.SKNO-1 278 bp overlap
ChIP aortic-endothelial-cell_D16 GSE139377.ERG.aortic-endothelial-cell_D16 186 bp overlap
EZH2 17 datasets
ChIP GM23338 ENCFF613YON 343 bp overlap
ChIP H1 ENCFF232NZA 548 bp overlap
ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 201 bp overlap
ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 159 bp overlap
ChIP LNCaP GSE39459.EZH2.LNCaP 546 bp overlap
ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 302 bp overlap
ChIP THP-1 GSE135024.EZH2.THP-1 519 bp overlap
ChIP astrocyte ENCFF365JTP 548 bp overlap
ChIP astrocyte ENCFF365JTP 401 bp overlap
ChIP astrocyte ENCFF365JTP 66 bp overlap
ChIP endothelial cell of umbilical vein ENCFF539AKL 548 bp overlap
ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 548 bp overlap
ChIP fibroblast_LUNG ENCSR000ARO.EZH2.fibroblast_LUNG 548 bp overlap
ChIP mammary epithelial cell ENCFF224GAI 476 bp overlap
ChIP neural ENCSR511CUH.EZH2.neural 356 bp overlap
ChIP neural progenitor cell ENCFF018MKA 104 bp overlap
ChIP neural progenitor cell ENCFF472NFV 548 bp overlap
FEZF2 2 datasets
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
FOXA1 1 dataset
ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 507 bp overlap
FOXA2 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 51 bp overlap
FOXJ3 1 dataset
ChIP HepG2 ENCFF430OSX 50 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 466 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 377 bp overlap
GATA4 2 datasets
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 59 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 282 bp overlap
GATA6 1 dataset
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 54 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 234 bp overlap
INSM1 1 dataset
Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap
JARID2 6 datasets
ChIP EDOMIPS2 GSE48516.JARID2.EDOMIPS2 253 bp overlap
ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 548 bp overlap
ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 548 bp overlap
ChIP UTEIPS11 GSE48516.JARID2.UTEIPS11 312 bp overlap
ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 327 bp overlap
ChIP UTEIPS7 GSE48516.JARID2.UTEIPS7 548 bp overlap
JUN 1 dataset
ChIP HUES-8 GSE109524.JUN.HUES-8 175 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 398 bp overlap
KDM5B 1 dataset
ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 133 bp overlap
KLF13 1 dataset
Motif DE_12h DE_12h-KLF13_MA0657.2 17 bp overlap
MAZ 1 dataset
Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap
MCRS1 1 dataset
ChIP Huh-7 GSE97411.MCRS1.Huh-7 245 bp overlap
MYBL2 1 dataset
Motif DE_12h DE_12h-MYBL2_MA0777.1 15 bp overlap
MYC 1 dataset
ChIP CD34 GSE85488.MYC.CD34 113 bp overlap
NANOG 4 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 548 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 383 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 321 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 337 bp overlap
NELFE 1 dataset
ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 216 bp overlap
Nr2e3 1 dataset
Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap
ONECUT1 1 dataset
ChIP H9 ERP004206.ONECUT1.H9 120 bp overlap
PATZ1 1 dataset
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
PAX6 1 dataset
ChIP EndoC-betaH2 GSE87530.PAX6.EndoC-betaH2 179 bp overlap
POU5F1 6 datasets
ChIP BG03 GSE21614.POU5F1.BG03 159 bp overlap
ChIP DE_D1 DED1-OCT4_Batch_II 406 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 354 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 196 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 115 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 377 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 252 bp overlap
Plagl1 1 dataset
Motif DE_12h DE_12h-Plagl1_MA1615.2 8 bp overlap
RAD21 1 dataset
ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 235 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 308 bp overlap
RNF2 1 dataset
ChIP H1 ENCFF239FFS 280 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 548 bp overlap
SMARCA4 3 datasets
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 309 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 285 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 344 bp overlap
SMARCB1 1 dataset
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 382 bp overlap
SMC3 1 dataset
ChIP neural ENCSR404BPV.SMC3.neural 265 bp overlap
SOX2 1 dataset
ChIP hiPSC GSE56567.SOX2.hiPSC 261 bp overlap
SUZ12 8 datasets
ChIP Aska-SS GSE108025.SUZ12.Aska-SS 436 bp overlap
ChIP H1 ENCFF881NFR 548 bp overlap
ChIP HEK293T_PCGF1356fl GSE119618.SUZ12.HEK293T_PCGF1356fl 204 bp overlap
ChIP HEK293T_PCGF135fl GSE119618.SUZ12.HEK293T_PCGF135fl 119 bp overlap
ChIP HEK293T_PCGF2fl GSE119618.SUZ12.HEK293T_PCGF2fl 125 bp overlap
ChIP LNCaP GSE39459.SUZ12.LNCaP 407 bp overlap
ChIP NT2-D1 ENCSR000EXH.SUZ12.NT2-D1 342 bp overlap
ChIP WA01 ENCSR000ATS.SUZ12.WA01 450 bp overlap
TCF12 1 dataset
ChIP H1 ENCFF203EBH 61 bp overlap
TET2 1 dataset
ChIP Jurkat_RUNX1KD GSE85524.TET2.Jurkat_RUNX1KD 229 bp overlap
TFAP2A 2 datasets
Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap
Motif DE_12h DE_12h-TFAP2A_MA0872.1 13 bp overlap
TFAP2B 2 datasets
Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap
Motif DE_12h DE_12h-TFAP2B_MA0813.1 13 bp overlap
TFAP2C 3 datasets
Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap
Motif DE_12h DE_12h-TFAP2C_MA0815.1 13 bp overlap
ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 536 bp overlap
TFAP2E 1 dataset
Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap
TFDP1 1 dataset
Motif DE_12h DE_12h-TFDP1_MA1122.2 8 bp overlap
Vdr 1 dataset
Motif DE_12h DE_12h-Vdr_MA0693.4 7 bp overlap
YY1 2 datasets
ChIP Huh-7 GSE97411.YY1.Huh-7 386 bp overlap
ChIP WA01 ENCSR000BKD.YY1.WA01 242 bp overlap
ZKSCAN3 1 dataset
Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF143 1 dataset
ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 180 bp overlap
ZNF148 1 dataset
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
ZNF213 2 datasets
Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap
Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap
ZNF324 1 dataset
Motif DE_12h DE_12h-ZNF324_MA1977.2 14 bp overlap
ZNF407 1 dataset
ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 155 bp overlap
ZNF460 1 dataset
Motif DE_12h DE_12h-ZNF460_MA1596.1 16 bp overlap
ZNF737 1 dataset
ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 190 bp overlap
ZNF816 1 dataset
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 169 bp overlap
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