chr4 : 77,128,136 77,129,079
943 bp 73 TFs 3 linked genes
This 943 bp open chromatin element is linked to CCNG2, CCNI, and SEPTIN11 and is bound by 73 transcription factors.
Linked Genes
3 genes
Gene Expression Dist. to TSS Distance Link type
CCNG2 28.6 kb Distal Multiome
CCNI 52.6 kb Distal Multiome
SEPTIN11 178.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:77,123,136 – 77,134,079
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
73 transcription factors
Source
Cell type
ASCL1 1 dataset
ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 124 bp overlap
Ascl2 5 datasets
Motif DE_36h DE_36h-Ascl2_MA0816.1 10 bp overlap
Motif DE_48h DE_48h-Ascl2_MA0816.1 10 bp overlap
Motif DE_48h DE_48h-Ascl2_MA0816.1 10 bp overlap
Motif DE_60h DE_60h-Ascl2_MA0816.1 10 bp overlap
Motif DE_60h DE_60h-Ascl2_MA0816.1 10 bp overlap
BCL6 1 dataset
ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 186 bp overlap
BHLHE22 9 datasets
Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_36h DE_36h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_48h DE_48h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap
Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap
BRD4 1 dataset
ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 476 bp overlap
Bhlha15 3 datasets
Motif DE_36h DE_36h-Bhlha15_MA1472.3 8 bp overlap
Motif DE_48h DE_48h-Bhlha15_MA1472.3 8 bp overlap
Motif DE_60h DE_60h-Bhlha15_MA1472.3 8 bp overlap
CASZ1 1 dataset
ChIP rhabdomyosarcoma_Trametinib GSE126143.CASZ1.rhabdomyosarcoma_Trametinib 328 bp overlap
CHD4 1 dataset
ChIP SCMC GSE155861.CHD4.SCMC 422 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 292 bp overlap
DACH1 1 dataset
ChIP K-562 ENCSR030TJP.DACH1.K-562 401 bp overlap
DMRT3 9 datasets
Motif DE_36h DE_36h-DMRT3_MA0610.2 7 bp overlap
Motif DE_36h DE_36h-DMRT3_MA0610.2 7 bp overlap
Motif DE_48h DE_48h-DMRT3_MA0610.2 7 bp overlap
Motif DE_48h DE_48h-DMRT3_MA0610.2 7 bp overlap
Motif DE_48h DE_48h-DMRT3_MA0610.2 7 bp overlap
Motif DE_60h DE_60h-DMRT3_MA0610.2 7 bp overlap
Motif DE_60h DE_60h-DMRT3_MA0610.2 7 bp overlap
Motif DE_60h DE_60h-DMRT3_MA0610.2 7 bp overlap
Motif DE_72h DE_72h-DMRT3_MA0610.2 7 bp overlap
ESRRA 2 datasets
Motif DE_48h DE_48h-ESRRA_MA0592.4 9 bp overlap
Motif DE_60h DE_60h-ESRRA_MA0592.4 9 bp overlap
EZH2 1 dataset
ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 224 bp overlap
FEZF1 3 datasets
ChIP HEK293 ENCFF528YED 271 bp overlap
ChIP HEK293 ENCSR827NWO.FEZF1.HEK293 361 bp overlap
ChIP HEK293 GSE76494.FEZF1.HEK293 251 bp overlap
FOXP2 4 datasets
Motif DE_36h DE_36h-FOXP2_MA0593.2 9 bp overlap
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
Motif DE_60h DE_60h-FOXP2_MA0593.2 9 bp overlap
Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 571 bp overlap
ChIP DE DE-GATA4-2 543 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 516 bp overlap
ChIP DE DE-GATA6-2 449 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 435 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 551 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 336 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 734 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 509 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 343 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 292 bp overlap
Gata3 3 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HDAC2 2 datasets
ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 312 bp overlap
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 470 bp overlap
HDAC3 1 dataset
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 396 bp overlap
IRF1 1 dataset
ChIP K-562_EPZ GSE129380.IRF1.K-562_EPZ 253 bp overlap
ISL2 3 datasets
Motif DE_36h DE_36h-ISL2_MA0914.2 6 bp overlap
Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap
Motif DE_60h DE_60h-ISL2_MA0914.2 6 bp overlap
KLF1 7 datasets
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_36h DE_36h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap
Motif DE_60h DE_60h-KLF1_MA0493.3 8 bp overlap
Motif DE_72h DE_72h-KLF1_MA0493.3 8 bp overlap
KLF2 7 datasets
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_36h DE_36h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap
Motif DE_60h DE_60h-KLF2_MA1515.2 8 bp overlap
Motif DE_72h DE_72h-KLF2_MA1515.2 8 bp overlap
KLF4 7 datasets
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_36h DE_36h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap
Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap
Motif DE_60h DE_60h-KLF4_MA0039.5 8 bp overlap
Motif DE_72h DE_72h-KLF4_MA0039.5 8 bp overlap
KLF5 7 datasets
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_36h DE_36h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap
Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap
MAFF 4 datasets
Motif DE_36h DE_36h-MAFF_MA0495.4 11 bp overlap
Motif DE_48h DE_48h-MAFF_MA0495.4 11 bp overlap
Motif DE_60h DE_60h-MAFF_MA0495.4 11 bp overlap
Motif DE_72h DE_72h-MAFF_MA0495.4 11 bp overlap
MSC 7 datasets
Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap
Motif DE_36h DE_36h-MSC_MA0665.1 10 bp overlap
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
Motif DE_48h DE_48h-MSC_MA0665.1 10 bp overlap
Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap
Motif DE_60h DE_60h-MSC_MA0665.1 10 bp overlap
Motif DE_72h DE_72h-MSC_MA0665.1 10 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 594 bp overlap
MYF5 3 datasets
Motif DE_36h DE_36h-MYF5_MA1641.2 8 bp overlap
Motif DE_48h DE_48h-MYF5_MA1641.2 8 bp overlap
Motif DE_60h DE_60h-MYF5_MA1641.2 8 bp overlap
MYOD1 7 datasets
Motif DE_36h DE_36h-MYOD1_MA0499.3 9 bp overlap
Motif DE_48h DE_48h-MYOD1_MA0499.3 9 bp overlap
Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap
ChIP RD GSE137168.MYOD1.RD 206 bp overlap
ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 322 bp overlap
ChIP RH4 GSE83726.MYOD1.RH4 468 bp overlap
ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 376 bp overlap
MYOG 2 datasets
ChIP RH4 GSE83726.MYOG.RH4 238 bp overlap
ChIP RH4_DMSO-6H GSE116344.MYOG.RH4_DMSO-6H 301 bp overlap
Mafb 4 datasets
Motif DE_36h DE_36h-Mafb_MA0117.3 11 bp overlap
Motif DE_48h DE_48h-Mafb_MA0117.3 11 bp overlap
Motif DE_60h DE_60h-Mafb_MA0117.3 11 bp overlap
Motif DE_72h DE_72h-Mafb_MA0117.3 11 bp overlap
NEUROD1 3 datasets
Motif DE_36h DE_36h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_48h DE_48h-NEUROD1_MA1109.2 8 bp overlap
Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap
NEUROG2 1 dataset
ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 230 bp overlap
NHLH1 2 datasets
Motif DE_48h DE_48h-NHLH1_MA0048.3 9 bp overlap
Motif DE_60h DE_60h-NHLH1_MA0048.3 9 bp overlap
NRL 4 datasets
Motif DE_36h DE_36h-NRL_MA0842.3 12 bp overlap
Motif DE_48h DE_48h-NRL_MA0842.3 12 bp overlap
Motif DE_60h DE_60h-NRL_MA0842.3 12 bp overlap
Motif DE_72h DE_72h-NRL_MA0842.3 12 bp overlap
Neurod2 12 datasets
Motif DE_36h DE_36h-Neurod2_MA0668.3 8 bp overlap
Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap
Motif DE_36h DE_36h-Neurod2_MA1993.2 6 bp overlap
Motif DE_48h DE_48h-Neurod2_MA0668.3 8 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_48h DE_48h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap
Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap
Nr5A2 2 datasets
Motif DE_48h DE_48h-Nr5A2_MA0505.3 9 bp overlap
Motif DE_60h DE_60h-Nr5A2_MA0505.3 9 bp overlap
OSR2 2 datasets
Motif DE_48h DE_48h-OSR2_MA1646.2 8 bp overlap
Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap
Olig2 9 datasets
Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap
Motif DE_36h DE_36h-Olig2_MA1997.2 6 bp overlap
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_48h DE_48h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap
Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap
POLR2A 1 dataset
ChIP prostate gland ENCFF881OMH 417 bp overlap
Ptf1A 7 datasets
Motif DE_36h DE_36h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_36h DE_36h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_48h DE_48h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap
Motif DE_72h DE_72h-Ptf1A_MA1619.2 8 bp overlap
RAD21 1 dataset
ChIP RH4 GSE83726.RAD21.RH4 292 bp overlap
RBBP4 1 dataset
ChIP SCMC GSE155861.RBBP4.SCMC 620 bp overlap
REST 2 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
RORA 2 datasets
Motif DE_48h DE_48h-RORA_MA0071.1 10 bp overlap
Motif DE_60h DE_60h-RORA_MA0071.1 10 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 286 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 540 bp overlap
SOX17_M 2 datasets
ChIP DE_D2 DED2-SOX17-M_Batch_II 301 bp overlap
ChIP DE_D2 DED2-SOX17-M_Batch_II 83 bp overlap
SOX8 2 datasets
ChIP RH4 GSE116344.SOX8.RH4 219 bp overlap
ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 208 bp overlap
SREBP2 1 dataset
ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 284 bp overlap
TAL1::TCF3 3 datasets
Motif DE_36h DE_36h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_48h DE_48h-TAL1TCF3_MA0091.2 10 bp overlap
Motif DE_60h DE_60h-TAL1TCF3_MA0091.2 10 bp overlap
TCF3 1 dataset
ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 168 bp overlap
TCF4 1 dataset
ChIP GEN2-2 GSE76147.TCF4.GEN2-2 111 bp overlap
TFAP4 10 datasets
Motif DE_36h DE_36h-TFAP4_MA0691.1 10 bp overlap
Motif DE_36h DE_36h-TFAP4_MA0691.1 10 bp overlap
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
Motif DE_48h DE_48h-TFAP4_MA0691.1 10 bp overlap
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
Motif DE_60h DE_60h-TFAP4_MA0691.1 10 bp overlap
Motif DE_72h DE_72h-TFAP4_MA0691.1 10 bp overlap
ChIP K562 ENCFF727PXG 467 bp overlap
ChIP K562 ENCFF727PXG 545 bp overlap
ChIP Kasumi-1 GSE45738.TFAP4.Kasumi-1 471 bp overlap
TFAP4::FLI1 6 datasets
Motif DE_36h DE_36h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_48h DE_48h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_48h DE_48h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_60h DE_60h-TFAP4FLI1_MA1967.2 14 bp overlap
Motif DE_72h DE_72h-TFAP4FLI1_MA1967.2 14 bp overlap
THRB 2 datasets
Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap
Motif DE_60h DE_60h-THRB_MA1576.2 18 bp overlap
TRPS1 3 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tcf12 9 datasets
Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap
Motif DE_36h DE_36h-Tcf12_MA0521.3 6 bp overlap
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_48h DE_48h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap
Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap
Tcf21 7 datasets
Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap
Motif DE_36h DE_36h-Tcf21_MA0832.2 10 bp overlap
Motif DE_48h DE_48h-Tcf21_MA0832.2 10 bp overlap
Motif DE_48h DE_48h-Tcf21_MA0832.2 10 bp overlap
Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap
Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap
Motif DE_72h DE_72h-Tcf21_MA0832.2 10 bp overlap
Twist2 9 datasets
Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap
Motif DE_36h DE_36h-Twist2_MA0633.3 6 bp overlap
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_48h DE_48h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap
Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap
ZBTB12 3 datasets
Motif DE_36h DE_36h-ZBTB12_MA1649.2 7 bp overlap
Motif DE_48h DE_48h-ZBTB12_MA1649.2 7 bp overlap
Motif DE_60h DE_60h-ZBTB12_MA1649.2 7 bp overlap
ZBTB18 3 datasets
Motif DE_36h DE_36h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_48h DE_48h-ZBTB18_MA0698.2 11 bp overlap
Motif DE_60h DE_60h-ZBTB18_MA0698.2 11 bp overlap
ZFHX2 1 dataset
ChIP HEK293 ENCFF167TUA 455 bp overlap
ZNF317 4 datasets
Motif DE_36h DE_36h-ZNF317_MA1593.2 8 bp overlap
Motif DE_48h DE_48h-ZNF317_MA1593.2 8 bp overlap
Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap
Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap
ZNF341 3 datasets
Motif DE_36h DE_36h-ZNF341_MA1655.2 8 bp overlap
Motif DE_48h DE_48h-ZNF341_MA1655.2 8 bp overlap
Motif DE_60h DE_60h-ZNF341_MA1655.2 8 bp overlap
ZNF449 5 datasets
Motif DE_36h DE_36h-ZNF449_MA1656.2 10 bp overlap
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap
Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap
Motif DE_72h DE_72h-ZNF449_MA1656.2 10 bp overlap
ZNF682 4 datasets
Motif DE_36h DE_36h-ZNF682_MA1599.2 11 bp overlap
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
Motif DE_60h DE_60h-ZNF682_MA1599.2 11 bp overlap
Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap
ZNF684 1 dataset
Motif DE_48h DE_48h-ZNF684_MA1600.2 14 bp overlap