chr4 : 52,304,701 – 52,305,742
1,041 bp 86 TFs 1 linked gene
This 1.0 kb open chromatin element is linked to SGCB and is bound by 86 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
SGCB 266.9 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:52,299,701 – 52,310,742
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
86 transcription factors
Source
Cell type
Arid3a 1 dataset
Motif DE_60h DE_60h-Arid3a_MA0151.1 6 bp overlap
BRD4 1 dataset
ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 194 bp overlap
E2F6 1 dataset
Motif DE_48h DE_48h-E2F6_MA0471.3 8 bp overlap
E2F8 1 dataset
Motif DE_48h DE_48h-E2F8_MA0865.3 9 bp overlap
EOMES 3 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
Motif DE_60h DE_60h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 265 bp overlap
ESR1 2 datasets
Motif DE_48h DE_48h-ESR1_MA0112.4 15 bp overlap
ChIP U2OS_E2 GSE26110.ESR1.U2OS_E2 129 bp overlap
ESRRB 1 dataset
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
EZH2 1 dataset
ChIP LNCaP GSE39459.EZH2.LNCaP 195 bp overlap
Esrrg 1 dataset
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
FOSL2 2 datasets
Motif DE_48h DE_48h-FOSL2_MA0478.2 10 bp overlap
Motif DE_60h DE_60h-FOSL2_MA0478.2 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 768 bp overlap
ChIP DE DE-FOXA2-2 630 bp overlap
FOXG1 1 dataset
Motif DE_60h DE_60h-FOXG1_MA0613.1 8 bp overlap
FOXN3 1 dataset
Motif DE_60h DE_60h-FOXN3_MA1489.1 8 bp overlap
GATA1 4 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 229 bp overlap
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 59 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 207 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 134 bp overlap
GATA2 2 datasets
Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 292 bp overlap
GATA4 10 datasets
ChIP DE DE-GATA4-1 836 bp overlap
ChIP DE DE-GATA4-2 873 bp overlap
Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 240 bp overlap
ChIP foregut GSE117136.GATA4.foregut 490 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 513 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 500 bp overlap
GATA5 2 datasets
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 822 bp overlap
ChIP DE DE-GATA6-2 856 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 546 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 769 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 881 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 736 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 639 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 854 bp overlap
ChIP foregut GSE117136.GATA6.foregut 554 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 345 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
HMBOX1 1 dataset
Motif DE_60h DE_60h-HMBOX1_MA0895.2 7 bp overlap
IKZF1 1 dataset
Motif DE_60h DE_60h-IKZF1_MA1508.2 8 bp overlap
IRF3 1 dataset
Motif DE_60h DE_60h-IRF3_MA1418.2 17 bp overlap
Irf1 1 dataset
Motif DE_60h DE_60h-Irf1_MA0050.4 11 bp overlap
KLF4 1 dataset
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 159 bp overlap
MGA 2 datasets
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
Motif DE_60h DE_60h-MGA_MA0801.1 8 bp overlap
MGA::EVX1 2 datasets
Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap
Motif DE_60h DE_60h-MGAEVX1_MA1960.2 11 bp overlap
Mecom 1 dataset
Motif DE_60h DE_60h-Mecom_MA0029.2 11 bp overlap
NR2C1 1 dataset
Motif DE_48h DE_48h-NR2C1_MA1535.2 6 bp overlap
NR2C2 1 dataset
Motif DE_48h DE_48h-NR2C2_MA1536.2 6 bp overlap
NR2F1 1 dataset
Motif DE_48h DE_48h-NR2F1_MA0017.3 12 bp overlap
NR2F2 1 dataset
Motif DE_48h DE_48h-NR2F2_MA1111.2 7 bp overlap
NR3C1 1 dataset
ChIP U2OS_SHHIC5 GSE65847.NR3C1.U2OS_SHHIC5 143 bp overlap
NR4A1 1 dataset
Motif DE_48h DE_48h-NR4A1_MA1112.3 8 bp overlap
NR4A2 1 dataset
Motif DE_48h DE_48h-NR4A2_MA0160.3 8 bp overlap
NR5A1 1 dataset
Motif DE_48h DE_48h-NR5A1_MA1540.3 12 bp overlap
Nr1H2 1 dataset
Motif DE_48h DE_48h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 1 dataset
Motif DE_48h DE_48h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 1 dataset
Motif DE_48h DE_48h-Nr1h3_MA2337.1 6 bp overlap
PAX5 1 dataset
ChIP fetal_testis GSE100639.PAX5.fetal_testis 165 bp overlap
PAX8 2 datasets
Motif DE_48h DE_48h-PAX8_MA2094.1 16 bp overlap
Motif DE_60h DE_60h-PAX8_MA2094.1 16 bp overlap
PAX9 2 datasets
Motif DE_48h DE_48h-PAX9_MA0781.2 16 bp overlap
Motif DE_60h DE_60h-PAX9_MA0781.2 16 bp overlap
PLAG1 1 dataset
Motif DE_48h DE_48h-PLAG1_MA0163.1 14 bp overlap
POU2F1::SOX2 2 datasets
Motif DE_48h DE_48h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_60h DE_60h-POU2F1SOX2_MA1962.1 17 bp overlap
PPARG 1 dataset
Motif DE_48h DE_48h-PPARG_MA0066.2 19 bp overlap
Pgr 1 dataset
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
Pou5f1::Sox2 2 datasets
Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap
Ppara 1 dataset
Motif DE_48h DE_48h-Ppara_MA2338.1 7 bp overlap
RARA 1 dataset
Motif DE_48h DE_48h-RARA_MA0729.1 18 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 859 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 802 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 744 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 161 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 621 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 650 bp overlap
SP5 1 dataset
Motif DE_48h DE_48h-SP5_MA1965.2 6 bp overlap
Spi1 1 dataset
Motif DE_60h DE_60h-Spi1_MA0080.7 13 bp overlap
Stat2 2 datasets
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
TAL1 2 datasets
ChIP CD34 GSE52924.TAL1.CD34 106 bp overlap
ChIP CHRF28811 ERP008568.TAL1.CHRF28811 226 bp overlap
TBR1 2 datasets
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
Motif DE_60h DE_60h-TBR1_MA0802.2 9 bp overlap
TBX1 2 datasets
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
Motif DE_60h DE_60h-TBX1_MA0805.1 8 bp overlap
TBX15 2 datasets
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
Motif DE_60h DE_60h-TBX15_MA0803.1 8 bp overlap
TBX18 2 datasets
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
Motif DE_60h DE_60h-TBX18_MA1565.2 9 bp overlap
TBX2 2 datasets
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
Motif DE_60h DE_60h-TBX2_MA0688.2 9 bp overlap
TBX20 2 datasets
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
Motif DE_60h DE_60h-TBX20_MA0689.1 11 bp overlap
TBX21 2 datasets
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
Motif DE_60h DE_60h-TBX21_MA0690.3 10 bp overlap
TBX3 2 datasets
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
Motif DE_60h DE_60h-TBX3_MA1566.3 9 bp overlap
TBX4 2 datasets
Motif DE_48h DE_48h-TBX4_MA0806.1 8 bp overlap
Motif DE_60h DE_60h-TBX4_MA0806.1 8 bp overlap
TBX5 2 datasets
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
Motif DE_60h DE_60h-TBX5_MA0807.1 8 bp overlap
TCF7L1 1 dataset
Motif DE_60h DE_60h-TCF7L1_MA1421.1 12 bp overlap
TFDP1 1 dataset
Motif DE_48h DE_48h-TFDP1_MA1122.2 8 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
Tbx6 2 datasets
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
Motif DE_60h DE_60h-Tbx6_MA1567.3 9 bp overlap
Tfcp2l1 3 datasets
Motif DE_48h DE_48h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_60h DE_60h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_60h DE_60h-Tfcp2l1_MA0145.2 14 bp overlap
ZBTB6 2 datasets
Motif DE_48h DE_48h-ZBTB6_MA1581.2 9 bp overlap
Motif DE_60h DE_60h-ZBTB6_MA1581.2 9 bp overlap
ZFP42 2 datasets
Motif DE_48h DE_48h-ZFP42_MA1651.2 13 bp overlap
Motif DE_60h DE_60h-ZFP42_MA1651.2 13 bp overlap
ZNF135 2 datasets
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
Motif DE_48h DE_48h-ZNF135_MA1587.1 14 bp overlap
ZNF143 1 dataset
Motif DE_48h DE_48h-ZNF143_MA0088.2 16 bp overlap
ZNF184 1 dataset
Motif DE_60h DE_60h-ZNF184_MA2120.1 13 bp overlap
ZNF213 1 dataset
Motif DE_48h DE_48h-ZNF213_MA2121.1 12 bp overlap
ZNF24 1 dataset
Motif DE_60h DE_60h-ZNF24_MA1124.1 13 bp overlap
ZNF257 1 dataset
Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap
ZNF460 1 dataset
Motif DE_48h DE_48h-ZNF460_MA1596.1 16 bp overlap
ZNF558 1 dataset
Motif DE_60h DE_60h-ZNF558_MA2335.1 29 bp overlap
ZNF652 1 dataset
Motif DE_60h DE_60h-ZNF652_MA1657.2 9 bp overlap
ZNF680 1 dataset
Motif DE_60h DE_60h-ZNF680_MA1729.2 11 bp overlap
ZNF701 1 dataset
Motif DE_48h DE_48h-ZNF701_MA1987.2 17 bp overlap
ZNF766 1 dataset
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
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