chr4 : 25,696,358 – 25,696,698

340 bp 83 TFs 0 linked genes

This 340 bp open chromatin element has no linked target genes and is bound by 83 transcription factors.

Linked Genes

No linked genes

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

ATF2 1 dataset

Motif DE_72h DE_72h-ATF2_MA1632.2 10 bp overlap

Ahr::Arnt 1 dataset

Motif DE_72h DE_72h-AhrArnt_MA0006.2 5 bp overlap

BCL6 1 dataset

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 301 bp overlap

BRD4 2 datasets

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 314 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 201 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 254 bp overlap

CREB1 1 dataset

Motif DE_72h DE_72h-CREB1_MA0018.5 8 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF335XTP 290 bp overlap

Crx 1 dataset

Motif DE_72h DE_72h-Crx_MA0467.3 6 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 306 bp overlap

EZH2 1 dataset

ChIP dermal-fibroblast_Untransformed GSE126396.EZH2.dermal-fibroblast_Untransformed 265 bp overlap

FEZF2 1 dataset

Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap

FOSL2 1 dataset

Motif DE_72h DE_72h-FOSL2_MA0478.2 10 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 340 bp overlap

ChIP DE DE-FOXA2-2 340 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 186 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 155 bp overlap

GATA1::TAL1 1 dataset

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 3 datasets

Motif DE_72h DE_72h-GATA2_MA0036.4 7 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 241 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 276 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 206 bp overlap

GATA4 8 datasets

ChIP DE DE-GATA4-1 340 bp overlap

ChIP DE DE-GATA4-2 340 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP Hep-G2 GSE135714.GATA4.Hep-G2 168 bp overlap

ChIP foregut GSE117136.GATA4.foregut 330 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 340 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 263 bp overlap

GATA6 18 datasets

ChIP AGS GSE51705.GATA6.AGS 179 bp overlap

ChIP DE DE-GATA6-1 340 bp overlap

ChIP DE DE-GATA6-2 340 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 288 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 278 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 313 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 340 bp overlap

ChIP ESO-26 GSE132680.GATA6.ESO-26 314 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 340 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 340 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 287 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 257 bp overlap

ChIP foregut GSE117136.GATA6.foregut 340 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 336 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 340 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 340 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 288 bp overlap

GSC 1 dataset

Motif DE_72h DE_72h-GSC_MA0648.2 6 bp overlap

GSC2 1 dataset

Motif DE_72h DE_72h-GSC2_MA0891.2 6 bp overlap

Gata3 1 dataset

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HDAC2 1 dataset

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 285 bp overlap

HNF4A 3 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 122 bp overlap

Motif DE_72h DE_72h-HNF4A_MA1494.2 14 bp overlap

ChIP GP5D GSE51234.HNF4A.GP5D 340 bp overlap

Hnf1A 1 dataset

Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap

ID3 1 dataset

ChIP K-562 ENCSR005NMT.ID3.K-562 136 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 199 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 186 bp overlap

KDM1A 1 dataset

ChIP K-562 GSE117944.KDM1A.K-562 140 bp overlap

KLF5 1 dataset

ChIP GP5D GSE51234.KLF5.GP5D 333 bp overlap

MAML1 1 dataset

ChIP SCC_4h GSE156486.MAML1.SCC_4h 220 bp overlap

MITF 4 datasets

ChIP 501-mel GSE137522.MITF.501-mel 183 bp overlap

ChIP 501-mel_20ng_K243R GSE137522.MITF.501-mel_20ng_K243R 187 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 197 bp overlap

ChIP K-562 ENCSR797SWM.MITF.K-562 137 bp overlap

MNT 1 dataset

ChIP Hep-G2 ENCSR261EDU.MNT.Hep-G2 141 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 260 bp overlap

MYB 1 dataset

Motif DE_72h DE_72h-MYB_MA0100.4 6 bp overlap

MYC 1 dataset

ChIP GP5D GSE51234.MYC.GP5D 313 bp overlap

NEUROD1 3 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 192 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 331 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 160 bp overlap

NIPBL 2 datasets

ChIP GP5D GSE51234.NIPBL.GP5D 340 bp overlap

ChIP GP5D_SIRAD21 GSE51234.NIPBL.GP5D_SIRAD21 290 bp overlap

NR1H2::RXRA 1 dataset

Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2C1 1 dataset

Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap

NR2C2 1 dataset

Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap

Nr1H2 1 dataset

Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap

Nr1H4 1 dataset

Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap

Nr1h3 1 dataset

Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap

OTX1 1 dataset

Motif DE_72h DE_72h-OTX1_MA0711.2 6 bp overlap

OTX2 1 dataset

Motif DE_72h DE_72h-OTX2_MA0712.3 7 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 233 bp overlap

PDX1 2 datasets

ChIP hiPSC GSE125768.PDX1.hiPSC 220 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 150 bp overlap

PITX1 1 dataset

Motif DE_72h DE_72h-PITX1_MA0682.3 6 bp overlap

PITX3 1 dataset

Motif DE_72h DE_72h-PITX3_MA0714.2 6 bp overlap

Pparg::Rxra 1 dataset

Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap

RAD21 1 dataset

ChIP GP5D GSE51234.RAD21.GP5D 264 bp overlap

RHOXF1 1 dataset

Motif DE_72h DE_72h-RHOXF1_MA0719.2 6 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 190 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 340 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 340 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 340 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 286 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 137 bp overlap

SMC3 1 dataset

ChIP GP5D GSE51234.SMC3.GP5D 318 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 290 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 339 bp overlap

SOX4 1 dataset

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Sox6 1 dataset

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Sox7 1 dataset

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

TAL1 3 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 216 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 157 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 148 bp overlap

TCF7L1 1 dataset

Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap

TCF7L2 1 dataset

Motif DE_72h DE_72h-TCF7L2_MA0523.2 9 bp overlap

TFAP2A 2 datasets

Motif DE_72h DE_72h-TFAP2A_MA0003.5 9 bp overlap

ChIP WA09 GSE105081.TFAP2A.WA09 234 bp overlap

TFAP2B 1 dataset

Motif DE_72h DE_72h-TFAP2B_MA0812.2 9 bp overlap

TFAP2C 3 datasets

Motif DE_72h DE_72h-TFAP2C_MA0814.3 9 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 258 bp overlap

ChIP WA09 GSE105081.TFAP2C.WA09 148 bp overlap

TFAP2E 1 dataset

Motif DE_72h DE_72h-TFAP2E_MA1569.2 9 bp overlap

TFE3 1 dataset

ChIP K562 ENCFF697ABG 173 bp overlap

THRA 1 dataset

Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap

THRB 1 dataset

Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 154 bp overlap

TRPS1 2 datasets

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

ChIP MCF-7 GSE133072.TRPS1.MCF-7 256 bp overlap

USF2 2 datasets

ChIP K-562 ENCSR359NFW.USF2.K-562 141 bp overlap

ChIP K562 ENCFF306QPU 269 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 117 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 213 bp overlap

Zfp809 1 dataset

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap