chr3:184,558,752–184,559,234

chr3 : 184,558,752 – 184,559,234

482 bp 58 TFs 9 linked genes

This 482 bp open chromatin element is linked to 9 target genes and is bound by 58 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
EPHB3		2.5 kb	Proximal	Proximity
MAGEF1		153.2 kb	Distal	Multiome
ENSG00000272970		153.3 kb	Distal	Multiome
POLR2H		197.2 kb	Distal	Multiome
CLCN2		197.3 kb	Distal	Multiome
FAM131A		223.0 kb	Distal	Multiome
EIF4G1		244.4 kb	Distal	Multiome
VPS8		253.3 kb	Distal	Multiome
PSMD2		259.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

58 transcription factors

ChIP VCaP_DHT24H GSE58428.AR.VCaP_DHT24H 52 bp overlap

ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 241 bp overlap

ChIP VCaP_DHT24H_SHRUNX1 GSE58428.AR.VCaP_DHT24H_SHRUNX1 94 bp overlap

ARID1A 2 datasets

ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 62 bp overlap

ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 111 bp overlap

ASH2L 2 datasets

ChIP VCaP GSE60841.ASH2L.VCaP 71 bp overlap

ChIP VCaP_R1881 GSE60841.ASH2L.VCaP_R1881 69 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 160 bp overlap

BAF155 1 dataset

ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 112 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 250 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 254 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 344 bp overlap

BRD4 9 datasets

ChIP COLO-205 GSE73319.BRD4.COLO-205 482 bp overlap

ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 83 bp overlap

ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 120 bp overlap

ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 76 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 89 bp overlap

ChIP MCF-7_ARID1A-KO GSE123284.BRD4.MCF-7_ARID1A-KO 412 bp overlap

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 267 bp overlap

ChIP VCaP_Darolutamide GSE148358.BRD4.VCaP_Darolutamide 62 bp overlap

ChIP VCaP_R1881 GSE148358.BRD4.VCaP_R1881 100 bp overlap

CBFA2T3 1 dataset

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 208 bp overlap

ChIP HeLa-S3 ENCSR219MKK.DEK.HeLa-S3 136 bp overlap

ChIP PDAC GSE64557.ELF3.PDAC 86 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 289 bp overlap

EP300 1 dataset

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 369 bp overlap

ChIP VCaP GSE83650.ERG.VCaP 59 bp overlap

ChIP VCaP GSE98809.ERG.VCaP 59 bp overlap

ChIP VCaP_DHT GSE79128.ERG.VCaP_DHT 66 bp overlap

ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 128 bp overlap

ChIP MCF-7_DHT GSE99626.ESR1.MCF-7_DHT 93 bp overlap

ChIP WTC11 ENCFF812SCD 316 bp overlap

EZH2 3 datasets

ChIP SU-DHL-6 GSE134136.EZH2.SU-DHL-6 170 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 94 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 149 bp overlap

FOXA1 3 datasets

ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 77 bp overlap

ChIP LS180 GSE140533.FOXA1.LS180 205 bp overlap

ChIP VCaP_ETOH24H GSE58428.FOXA1.VCaP_ETOH24H 54 bp overlap

FOXA2 3 datasets

ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 69 bp overlap

ChIP DE DE-FOXA2-1 294 bp overlap

ChIP DE DE-FOXA2-2 385 bp overlap

GABPA 1 dataset

ChIP MCF-7 ENCFF735CHO 73 bp overlap

GABPB1 1 dataset

ChIP HepG2 ENCFF315AWN 75 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 482 bp overlap

ChIP DE DE-GATA4-2 482 bp overlap

ChIP foregut GSE117136.GATA4.foregut 437 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 482 bp overlap

ChIP DE DE-GATA6-2 482 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 419 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 481 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 482 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 476 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 482 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 422 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 165 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 482 bp overlap

ChIP foregut GSE117136.GATA6.foregut 468 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 331 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF939VKA 236 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 169 bp overlap

HNF4A 2 datasets

ChIP GP5D GSE51234.HNF4A.GP5D 92 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 363 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 142 bp overlap

JARID2 2 datasets

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 200 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 150 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 315 bp overlap

ChIP GP5D GSE51234.KLF5.GP5D 117 bp overlap

MED1 3 datasets

ChIP VCaP GSE148358.MED1.VCaP 389 bp overlap

ChIP VCaP_Darolutamide GSE148358.MED1.VCaP_Darolutamide 214 bp overlap

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 482 bp overlap

ChIP GP5D GSE51234.MYC.GP5D 144 bp overlap

NANOG 7 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 310 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 213 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 285 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 252 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 240 bp overlap

ChIP hESC GSE18292.NANOG.hESC 280 bp overlap

ChIP hESC GSE20650.NANOG.hESC 175 bp overlap

POU2F1 1 dataset

ChIP 22Rv1_Veh GSE123565.POU2F1.22Rv1_Veh 282 bp overlap

POU5F1 7 datasets

ChIP H1 ENCFF698ZAP 183 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 278 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 482 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 189 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 159 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 353 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 218 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 238 bp overlap

ChIP MCF-7 ENCFF782EZS 62 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 128 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 214 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 223 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 438 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 402 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 329 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 316 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 338 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 302 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 336 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 392 bp overlap

SMAD3 4 datasets

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 207 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 148 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 205 bp overlap

ChIP hESC GSE29422.SMAD3.hESC 157 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 287 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 233 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 227 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 239 bp overlap

SMARCC1 3 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 334 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 171 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 273 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 284 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 482 bp overlap

SOX2 3 datasets

ChIP H9 GSE46837.SOX2.H9 278 bp overlap

ChIP hESC GSE18292.SOX2.hESC 95 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 290 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 186 bp overlap

STAT3 1 dataset

ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 174 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 272 bp overlap

TAL1 3 datasets

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 165 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 279 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 222 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 120 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 142 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 160 bp overlap

ZNF217 2 datasets

ChIP MCF-7 ENCFF379OSU 112 bp overlap

ChIP MCF-7 ENCSR465XQW.ZNF217.MCF-7 68 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 144 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 107 bp overlap