chr1:31,647,107–31,647,947

chr1 : 31,647,107 – 31,647,947

840 bp 49 TFs 6 linked genes

This 840 bp open chromatin element is linked to 6 target genes and is bound by 49 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PEF1-AS1		2.1 kb	Proximal	Proximity
ENSG00000264078		2.4 kb	Proximal	Proximity
PEF1		2.5 kb	Proximal	Proximity
SPOCD1		168.4 kb	Distal	Multiome
SERINC2		234.4 kb	Distal	Multiome
PTP4A2		290.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

49 transcription factors

ChIP HepG2 ENCFF423EJH 377 bp overlap

ChIP HCC1395 GSE63581.BRD4.HCC1395 360 bp overlap

ChIP leiomyoma_PT886 GSE128230.CDK8.leiomyoma_PT886 98 bp overlap

CEBPB 1 dataset

ChIP IMR-90 ENCFF468UGY 251 bp overlap

CREB1 1 dataset

ChIP Hep-G2 ENCSR000BVL.CREB1.Hep-G2 113 bp overlap

CTCF 39 datasets

ChIP AG04449 ENCFF248MBD 181 bp overlap

ChIP AG09309 ENCFF478XPS 277 bp overlap

ChIP AG10803 ENCFF549AQK 257 bp overlap

ChIP BJ ENCFF434HEC 311 bp overlap

ChIP BJ ENCSR000DQI.CTCF.BJ 245 bp overlap

ChIP IMR-90 ENCFF887MRH 245 bp overlap

ChIP IMR-90 ENCSR000EFI.CTCF.IMR-90 185 bp overlap

ChIP IMR-90_Ctrl GSE125639.CTCF.IMR-90_Ctrl 217 bp overlap

ChIP aorta_thoracic ENCSR668BTN.CTCF.aorta_thoracic 646 bp overlap

ChIP artery_tibial ENCSR699BEK.CTCF.artery_tibial 408 bp overlap

ChIP ascending aorta ENCFF138DXQ 385 bp overlap

ChIP ascending aorta ENCFF440JQB 345 bp overlap

ChIP ascending-aorta ENCSR846JKO.CTCF.ascending-aorta 291 bp overlap

ChIP ascending-aorta ENCSR555DCD.CTCF.ascending-aorta 223 bp overlap

ChIP astrocyte ENCSR000AOO.CTCF.astrocyte 197 bp overlap

ChIP breast epithelium ENCFF080KNR 437 bp overlap

ChIP breast_epithelium ENCSR661NXJ.CTCF.breast_epithelium 259 bp overlap

ChIP chondrocyte ENCFF134ORZ 383 bp overlap

ChIP chondrocyte ENCFF134ORZ 581 bp overlap

ChIP coronary artery ENCFF483TFF 195 bp overlap

ChIP coronary-artery ENCSR175FLL.CTCF.coronary-artery 291 bp overlap

ChIP fibroblast of the aortic adventitia ENCFF639DMR 217 bp overlap

ChIP fibroblast_AORTIC_ADVENTITIA ENCSR000DPY.CTCF.fibroblast_AORTIC_ADVENTITIA 193 bp overlap

ChIP fibroblast_LUNG ENCSR000DPM.CTCF.fibroblast_LUNG 121 bp overlap

ChIP fibroblast_PEDAL_DIGIT_SKIN ENCSR000DPP.CTCF.fibroblast_PEDAL_DIGIT_SKIN 127 bp overlap

ChIP fibroblast_PULMONARY_ARTERY ENCSR000DUX.CTCF.fibroblast_PULMONARY_ARTERY 124 bp overlap

ChIP fibroblast_SKIN_ABDOMEN ENCSR000DPV.CTCF.fibroblast_SKIN_ABDOMEN 191 bp overlap

ChIP fibroblast_SKIN_LEG ENCSR000DPG.CTCF.fibroblast_SKIN_LEG 172 bp overlap

ChIP lower leg skin ENCFF055ALO 365 bp overlap

ChIP osteoblast ENCFF491ZJZ 425 bp overlap

ChIP osteoblast ENCSR000APF.CTCF.osteoblast 282 bp overlap

ChIP placenta ENCFF029PHY 461 bp overlap

ChIP skin_lower-leg ENCSR252XWG.CTCF.skin_lower-leg 221 bp overlap

ChIP thoracic aorta ENCFF012WJQ 417 bp overlap

ChIP thoracic aorta ENCFF166PKA 203 bp overlap

ChIP thoracic-aorta ENCSR549TXG.CTCF.thoracic-aorta 367 bp overlap

ChIP tibial artery ENCFF882IXS 397 bp overlap

ChIP tibial-artery ENCSR079YAP.CTCF.tibial-artery 278 bp overlap

ChIP uterus ENCFF631BWF 305 bp overlap

CTCFL 1 dataset

ChIP FT282 GSE131931.CTCFL.FT282 192 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.DPF2.BIN-67_lentivirus-SMARCA4 197 bp overlap

EBF1 4 datasets

ChIP ASC GSE54889.EBF1.ASC 117 bp overlap

ChIP GM12878 ENCFF813OXE 172 bp overlap

ChIP MUTUL GSE75503.EBF1.MUTUL 198 bp overlap

ChIP NALM-6 GSE126300.EBF1.NALM-6 313 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 454 bp overlap

EP300 1 dataset

ChIP fibroblast_senescent GSE106146.EP300.fibroblast_senescent 186 bp overlap

ESR1 2 datasets

ChIP T-47D_PROG GSE68355.ESR1.T-47D_PROG 324 bp overlap

ChIP T-47D_siCont-IL6 GSE126004.ESR1.T-47D_siCont-IL6 241 bp overlap

ChIP Hep-G2 ENCSR681WHQ.ETS1.Hep-G2 162 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 727 bp overlap

ChIP DE DE-FOXA2-2 642 bp overlap

FOXK2 1 dataset

ChIP Hep-G2 ENCSR171FUX.FOXK2.Hep-G2 202 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 840 bp overlap

ChIP DE DE-GATA4-2 840 bp overlap

ChIP foregut GSE117136.GATA4.foregut 663 bp overlap

GATA6 6 datasets

ChIP DE DE-GATA6-1 840 bp overlap

ChIP DE DE-GATA6-2 840 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 256 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 756 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 791 bp overlap

ChIP foregut GSE117136.GATA6.foregut 647 bp overlap

Hand1::Tcf3 1 dataset

Motif DE_72h DE_72h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_72h DE_72h-Hmx2_MA0897.2 15 bp overlap

ChIP SK-N-SH ENCFF285GEQ 485 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 236 bp overlap

ChIP IMR-90 ENCSR000EFF.MAZ.IMR-90 112 bp overlap

MED1 6 datasets

ChIP hMSC-TERT4_4h GSE104537.MED1.hMSC-TERT4_4h 279 bp overlap

ChIP hMSC-TERT4_osteoblast-4H GSE113253.MED1.hMSC-TERT4_osteoblast-4H 422 bp overlap

ChIP hMSC-TERT4_osteoblast-D1 GSE113253.MED1.hMSC-TERT4_osteoblast-D1 293 bp overlap

ChIP hMSC-TERT4_osteoblast-D3 GSE113253.MED1.hMSC-TERT4_osteoblast-D3 481 bp overlap

ChIP hMSC-TERT4_osteoblast-D7 GSE113253.MED1.hMSC-TERT4_osteoblast-D7 499 bp overlap

ChIP hMSC-TERT4_undifferentiated GSE113253.MED1.hMSC-TERT4_undifferentiated 386 bp overlap

ChIP BJ GSE36570.MYC.BJ 130 bp overlap

NCOR1 1 dataset

ChIP HepG2 ENCFF685NAH 185 bp overlap

NKX2-2 1 dataset

Motif DE_72h DE_72h-NKX2-2_MA1645.2 8 bp overlap

NKX2-5 1 dataset

Motif DE_72h DE_72h-NKX2-5_MA0063.3 7 bp overlap

ChIP T-47D_PROG GSE68355.PGR.T-47D_PROG 267 bp overlap

ChIP T-47D_R5020 GSE68355.PGR.T-47D_R5020 249 bp overlap

ChIP T-47D_R5020-A1 GSE126859.PGR.T-47D_R5020-A1 241 bp overlap

ChIP T-47D_R5020-MTVL GSE126859.PGR.T-47D_R5020-MTVL 166 bp overlap

POLR2A 1 dataset

ChIP breast epithelium ENCFF065JSZ 129 bp overlap

PRDM15 2 datasets

ChIP Hep-G2 ENCSR011INW.PRDM15.Hep-G2 360 bp overlap

ChIP HepG2 ENCFF259LUZ 288 bp overlap

RCOR1 1 dataset

ChIP IMR-90 ENCSR000EFG.RCOR1.IMR-90 188 bp overlap

RELA 2 datasets

ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 150 bp overlap

ChIP HeLa-B2_TA_TNFA GSE24518.RELA.HeLa-B2_TA_TNFA 251 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 232 bp overlap

ChIP Hep-G2 ENCSR754MUD.SKI.Hep-G2 50 bp overlap

SMAD2 2 datasets

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

ChIP endoderm GSE29422.SMAD2.endoderm 241 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 840 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 360 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 840 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 840 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 227 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 217 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 840 bp overlap

STAT3 6 datasets

ChIP A139 GSE85579.STAT3.A139 282 bp overlap

ChIP HCC1187 GSE152203.STAT3.HCC1187 205 bp overlap

ChIP T-47D_JC4753 GSE126004.STAT3.T-47D_JC4753 216 bp overlap

ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 249 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 271 bp overlap

ChIP T-47D_JC5062 GSE126004.STAT3.T-47D_JC5062 294 bp overlap

TEAD1 3 datasets

ChIP H69 GSE62274.TEAD1.H69 154 bp overlap

ChIP adipocyte GSE140782.TEAD1.adipocyte 319 bp overlap

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 157 bp overlap

TEAD3 1 dataset

ChIP HepG2 ENCFF054UUL 371 bp overlap

TEAD4 7 datasets

ChIP BJ_fibroblast GSE114367.TEAD4.BJ_fibroblast 214 bp overlap

ChIP BJ_fibroblast_CD13-neg GSE114367.TEAD4.BJ_fibroblast_CD13-neg 191 bp overlap

ChIP Hep-G2 ENCSR000BRP.TEAD4.Hep-G2 223 bp overlap

ChIP HepG2 ENCFF006QNB 431 bp overlap

ChIP HepG2 ENCFF250NXO 155 bp overlap

ChIP SNU-216 GSE44416.TEAD4.SNU-216 155 bp overlap

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 372 bp overlap

YAP1 2 datasets

ChIP MCF-10A GSE97972.YAP1.MCF-10A 274 bp overlap

ChIP hiPSC GSE111930.YAP1.hiPSC 229 bp overlap

ZNF121 4 datasets

ChIP HEK293 ENCFF839FUF 238 bp overlap

ChIP Hep-G2 ENCSR945QEW.ZNF121.Hep-G2 155 bp overlap

ChIP HepG2 ENCFF343YSL 225 bp overlap

ChIP K562 ENCFF314GND 248 bp overlap

ZNF19 1 dataset

ChIP HEK293T GSE78099.ZNF19.HEK293T 272 bp overlap

ZNF573 1 dataset

ChIP HEK293T GSE78099.ZNF573.HEK293T 185 bp overlap

ZSCAN21 1 dataset

Motif DE_72h DE_72h-ZSCAN21_MA2336.1 7 bp overlap